AutismKB 2.0

Annotation Detail for NTF3


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Basic Information Top
Gene Symbol:NTF3 ( HDNF,MGC129711,NGF-2,NGF2,NT3 )
Gene Full Name: neurotrophin 3
Band: 12p13.31
Quick LinksEntrez ID:4908; OMIM: 162660; Uniprot ID:NTF3_HUMAN; ENSEMBL ID: ENSG00000185652; HGNC ID: 8023
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa04010MAPK signaling pathway
hsa04722Neurotrophin signaling pathway
No data
Pathway IDPathway Name
200182Trk receptor signaling mediated by the MAPK pathway
200128Neurotrophic factor-mediated Trk receptor signaling
200103p75(NTR)-mediated signaling
No data
No data
Related Diseases/Disorders Top
No data
No data
Desease Name
Alzheimer's disease
PSYCH
NEUROLOGICAL
schizophrenia
No data
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C014024 2,4,5,2',4',5'-hexachlorobiphenyl [3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in decreased expression of NTF3 mRNAaffects cotreatment|decreases expression 16984957
C023035 3,4,5,3',4'-pentachlorobiphenyl [3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in decreased expression of NTF3 mRNAaffects cotreatment|decreases expression 16984957
D020106 Acrylamide NTF3 protein inhibits the reaction [Acrylamide results in decreased activity of CHAT protein]decreases activity|decreases reaction 11779407
D000643 Ammonium Chloride Ammonium Chloride affects the expression of NTF3 mRNAaffects expression 16483693
D019324 beta-Naphthoflavone [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of NTF3 mRNAaffects cotreatment|decreases expression 18164116
D004390 Chlorpyrifos Chlorpyrifos results in decreased expression of NTF3 mRNAdecreases expression 18502319
D004052 Diethylnitrosamine [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of NTF3 mRNAaffects cotreatment|decreases expression 18164116
D004958 Estradiol Estradiol results in increased expression of NTF3 proteinincreases expression 15570173
D004958 Estradiol Progesterone inhibits the reaction [Estradiol results in increased expression of NTF3 protein]decreases reaction|increases expression 15570173
D005839 Gentamicins NTF3 protein results in decreased susceptibility to Gentamicinsdecreases response to substance 18024279
D009151 Mustard Gas IL10 protein affects the reaction [Mustard Gas affects the expression of NTF3 mRNA]affects expression|affects reaction 16173061
D009151 Mustard Gas Mustard Gas results in decreased expression of NTF3 mRNAdecreases expression 16173061
D010672 Phenytoin Phenytoin results in decreased expression of NTF3 mRNAdecreases expression 7841657
D011374 Progesterone Progesterone inhibits the reaction [Estradiol results in increased expression of NTF3 protein]decreases reaction|increases expression 15570173
D013749 Tetrachlorodibenzodioxin AHR gene mutant form inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of NTF3 mRNA]decreases expression|decreases reaction 16984957
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of NTF3 mRNAdecreases expression 16984957
D014212 Tretinoin [NTF3 protein co-treated with Tretinoin] results in increased expression of DLG4 proteinaffects cotreatment|increases expression 16996685
D014212 Tretinoin [NTF3 protein co-treated with Tretinoin] results in increased expression of MAP2 proteinaffects cotreatment|increases expression 16996685
D014212 Tretinoin [NTF3 protein co-treated with Tretinoin] results in increased expression of NES proteinaffects cotreatment|increases expression 16996685
D014212 Tretinoin [NTF3 protein co-treated with Tretinoin] results in increased expression of NTRK3 mRNAaffects cotreatment|increases expression 16996685
D014212 Tretinoin [Tretinoin co-treated with BDNF protein co-treated with NTF3 protein] results in decreased expression of MAP2 proteinaffects cotreatment|decreases expression 16646665
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Phenytoin 8.9610563481 6195326 3425630 8986270 9118846 9677735
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 8.9614514962 15322242 11752688
MESH:D000138 Acidosis Ammonium Chloride 3.6418287403
MESH:D058186 Acute Kidney Injury Gentamicins 4.6011274264
MESH:D000230 Adenocarcinoma Estradiol 2.1111473722
MESH:D000236 Adenoma beta-Naphthoflavone 6.9819389873
MESH:D000236 Adenoma Diethylnitrosamine 6.9810737359 6695378
MESH:D018248 Adenoma, Liver Cell 3,4,5,3',4'-pentachlorobiphenyl 18.0216628245
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 18.0218056438 17620307 17162532 19052882 19061943 16434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 18.0216835633
MESH:D000382 Agricultural Workers' Diseases Chlorpyrifos 4.4211874814 16611668 17119214
MESH:D000505 Alopecia Tretinoin 3.6615955085
MESH:D000740 Anemia Tetrachlorodibenzodioxin 3.0011748828
MESH:D001169 Arthritis, Experimental Tretinoin 3.1116412693
MESH:D001172 Arthritis, Rheumatoid Tretinoin 2.2716292516
MESH:D001249 Asthma Mustard Gas 5.0310378619
MESH:D001249 Asthma Tretinoin 5.0316456186
MESH:D050197 Atherosclerosis Phenytoin 3.9515136057
MESH:D001321 Autistic Disorder marker/mechanism 16289943
MESH:D001471 Barrett Esophagus Tretinoin 4.4716935849
MESH:D001768 Blister Mustard Gas 5.2419167455
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 9.1212125929
MESH:D001778 Blood Coagulation Disorders Tretinoin 9.1216206674 16197459
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.8915340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.8015746008
MESH:D020201 Brain Hemorrhage, Traumatic Progesterone 5.4317868700
MESH:D001930 Brain Injuries Progesterone 4.3315665606 15845082 15380490
MESH:D001943 Breast Neoplasms Acrylamide 2.9918183576 16253758
MESH:D001943 Breast Neoplasms Diethylnitrosamine 2.9917474063
MESH:D001943 Breast Neoplasms Estradiol 2.9912948864 19861407 14630087 17261762 17289903 18497071 16675129 17018787
MESH:D001943 Breast Neoplasms Progesterone 2.9917614352 15562024 16175315
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 2.9920435547
MESH:D001943 Breast Neoplasms Tretinoin 2.9916443354 16166294 16873071
MESH:D001989 Bronchiolitis Obliterans Mustard Gas 5.2415286001
MESH:D029481 Bronchitis, Chronic Mustard Gas 5.0717687719 10378619
MESH:D001997 Bronchopulmonary Dysplasia Tretinoin 4.6716813970
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 4.5516111702
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.8416835633
MESH:D018236 Carcinoma, Embryonal Tretinoin 5.2616168501
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 4.6318393292 16540662 17428255 20512989 20101231 19919837 20084675 20727157 20524982 16288022 19394651 16328049 20007298 19539802 18785209 18788625 17761372 17138121 16807293 19208518 19335982 17173139 17162532 16698587 16681979 16935385 18691550 18506893 19519916 16569478 18056438 18210153 20432363 19171122 18971187 20514400 18494052 17978847 19052882 16502159 20935162 19701751 16779866 3084413 11831363 16878318 19418558 17055752 21159647 10672840 10737359 16830150 3581430 20214788 18665156 18978308 19383236 19107877 19822196
MESH:D006528 Carcinoma, Hepatocellular Estradiol 4.6316924424
MESH:D006528 Carcinoma, Hepatocellular Tretinoin 4.631917145
MESH:D002294 Carcinoma, Squamous Cell Tretinoin 2.3016096774 16051514
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.3916120746 18850075 18670907
MESH:D002386 Cataract Tretinoin 3.1217460283
MESH:D002418 Cattle Diseases Acrylamide 5.5512510666
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 6.827505956 17174075 2727394 21159647
MESH:D002471 Cell Transformation, Neoplastic Estradiol 6.8218566989
MESH:D002493 Central Nervous System Diseases Phenytoin 5.374080065
MESH:D018290 Cervical Intraepithelial Neoplasia Tretinoin 4.6716129372
MESH:D018281 Cholangiocarcinoma 3,4,5,3',4'-pentachlorobiphenyl 16.5116628245
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 16.5119052882
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 16.5116835633
OMIM:601042 CHOREOATHETOSIS/SPASTICITY, EPISODIC Phenytoin 5.9511748493
MESH:D002822 Choriocarcinoma Tretinoin 5.2616461808
MESH:D002971 Cleft Lip Phenytoin 4.182227380
MESH:D002972 Cleft Palate Phenytoin 10.041687470 6856622 10789828 2227380 3877104 6862529
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 10.048697196 12621046 15340226 15668235 16354765
MESH:D002972 Cleft Palate Tretinoin 10.049407595
MESH:D003092 Colitis Tretinoin 3.7817035595
MESH:D003103 Coloboma Phenytoin 5.219212184
MESH:D000013 Congenital Abnormalities Phenytoin 9.5510627286
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 9.5514669216 17141729
MESH:D019465 Craniofacial Abnormalities 3,4,5,3',4'-pentachlorobiphenyl 5.5617686920
MESH:D019465 Craniofacial Abnormalities Phenytoin 5.569212184 8986270 19952982
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 5.5610048152 20055451 15322242
MESH:D019465 Craniofacial Abnormalities Tretinoin 5.569142499 14991402 9211117 17551590 9224671 9664655 9125849 16925845 8800419 10589399
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 4.2620387270
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 4.2617107852
MESH:D003928 Diabetic Nephropathies Estradiol 3.4619279558
MESH:D003929 Diabetic Neuropathies therapeutic 11779407
MESH:D003929 Diabetic Neuropathies Progesterone 4.5617187935
MESH:D004314 Down Syndrome marker/mechanism 16289943
OMIM:607208 DRAVET SYNDROME Phenytoin 5.4611748493
MESH:D003875 Drug Eruptions Phenytoin 5.5715024534
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 3.7819107877
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 3.7820420201
MESH:D004362 Drug Toxicity Gentamicins 8.5311033412 15033597
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 8.5311462148
MESH:D004487 Edema Mustard Gas 7.0211428647 9260866 11402378 11428631
MESH:D004487 Edema Tetrachlorodibenzodioxin 7.0212711302 11000095
MESH:D004489 Edema, Cardiac 3,4,5,3',4'-pentachlorobiphenyl 21.7017686920
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 21.7016714409 18230668 15322242
MESH:D004489 Edema, Cardiac Tretinoin 21.7018230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Phenytoin 9.8017654737
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Progesterone 9.8017692515
MESH:D016889 Endometrial Neoplasms Estradiol 7.5311473722 19148513 18566989
MESH:D016889 Endometrial Neoplasms Tretinoin 7.5316569247
MESH:D004715 Endometriosis Progesterone 9.1016134523
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 9.109294722 10568697
MESH:D004816 Epidermal Necrolysis, Toxic Phenytoin 5.2620235791
MESH:D004820 Epidermolysis Bullosa Phenytoin 6.331399206 6251365
MESH:D004828 Epilepsies, Partial Phenytoin 5.0111558140 17116037
MESH:D004827 Epilepsy Phenytoin 3.9620417680 11434505 821787
MESH:D017029 Epilepsy, Complex Partial Phenytoin 5.377750514
MESH:D004830 Epilepsy, Tonic-Clonic Phenytoin 5.153659116
MESH:D004890 Erythema Mustard Gas 5.249357497
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 5.2116302075
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 8.9711564622
MESH:D005124 Eye Abnormalities Tretinoin 8.979664655 16938888
MESH:D005234 Fatty Liver Diethylnitrosamine 3.2421071580 20387270
MESH:D005313 Fetal Death Phenytoin 10.9810627286
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 10.9811858732
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 8.8620067830
MESH:D005355 Fibrosis Tretinoin 8.8617994277
MESH:D005885 Gingival Hyperplasia Phenytoin 5.759029455
MESH:D019214 Gingival Overgrowth Phenytoin 6.3316390469 14659971
MESH:D005909 Glioblastoma Tretinoin 3.0417312396
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.6910696789
MESH:D006258 Head and Neck Neoplasms Tretinoin 3.2216096774
MESH:D034381 Hearing Loss therapeutic 18024279
MESH:D034381 Hearing Loss Gentamicins 4.9317868369 15968427 18024279 19130971
MESH:D006317 Hearing Loss, Noise-Induced Tretinoin 5.2616084493
MESH:D006330 Heart Defects, Congenital 3,4,5,3',4'-pentachlorobiphenyl 11.4620471113 17686920
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 11.4610048152 11294989
MESH:D006330 Heart Defects, Congenital Tretinoin 11.469664655 14991402
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.3911000095
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 2.9615340226 12621046 16120746
MESH:D006558 Herpes Genitalis Estradiol 5.1315709030
MESH:D019584 Hot Flashes Estradiol 3.8517088409
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 4.148697196 18606429 15340226 16354765 16959395
MESH:D006930 Hyperalgesia Tretinoin 3.2516870215
MESH:D053565 Hypercalciuria Gentamicins 5.7917652376
MESH:D017681 Hypereosinophilic Syndrome Tretinoin 4.6416778211
MESH:D020138 Hyperhomocysteinemia Phenytoin 4.7210459572
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 1.9218850075 18670907
MESH:D020244 Infarction, Middle Cerebral Artery Progesterone 4.4715869954
MESH:D007247 Infertility, Female Acrylamide 5.2611020651
MESH:D007248 Infertility, Male Acrylamide 4.2615355880 12507653 11020651 15749267
MESH:D007249 Inflammation Diethylnitrosamine 12.2118785209
MESH:D007249 Inflammation Mustard Gas 12.2117524151 11428631 11428620 11402378 8975870 16001271 9260866 9357497 11428647
MESH:D007249 Inflammation Progesterone 12.2115869954
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 12.2112200463 12878042
MESH:D007333 Insulin Resistance Estradiol 3.0016627594 16393666
MESH:D007410 Intestinal Diseases Tretinoin 3.8417994277
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 10.1216580747
MESH:D007569 Jaw Abnormalities Tretinoin 10.1217551590 15992940
MESH:D007673 Kidney Cortex Necrosis Gentamicins 5.8218842672
MESH:D007674 Kidney Diseases Estradiol 6.5815618244
MESH:D007674 Kidney Diseases Gentamicins 6.5818289764 17934191 19349640
MESH:D007680 Kidney Neoplasms Estradiol 3.0215610895
MESH:D007683 Kidney Tubular Necrosis, Acute Gentamicins 5.4811231351
MESH:D016773 Leishmaniasis, Cutaneous Gentamicins 4.5110219319
MESH:D007938 Leukemia Tretinoin 2.7917143497
MESH:D007951 Leukemia, Myeloid Tretinoin 3.7519285840 16932348 16482212
MESH:D015470 Leukemia, Myeloid, Acute Tretinoin 2.0816294345 19850784 17596541
MESH:D015473 Leukemia, Promyelocytic, Acute Tretinoin 3.1917712046 16788101 16891316 17301526 17339181 16331271 9834237 17506722 19035177 16823087 19642359 16935935 17217047 16766008 17649720 17368321 17107899 16140955 19075265 17294898 17361223 12679006 15748426 19225113 19029980
MESH:D017880 Limb Deformities, Congenital Tretinoin 3.349224671
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 2.8520032147 18665156 18407596 18522880 19638242
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 3.4714716833 14659978
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 3.4712878042
MESH:D008106 Liver Cirrhosis, Experimental Tretinoin 3.4718397230 16248980
MESH:D008107 Liver Diseases Chlorpyrifos 6.9015991261
MESH:D008107 Liver Diseases Diethylnitrosamine 6.9017034775
MESH:D008107 Liver Diseases Phenytoin 6.9014986274
MESH:D008113 Liver Neoplasms 2,4,5,2',4',5'-hexachlorobiphenyl 10.9416835634 18644402
MESH:D008113 Liver Neoplasms beta-Naphthoflavone 10.9421295105 19389873
MESH:D008113 Liver Neoplasms Diethylnitrosamine 10.9418978307 21278145 15885732 19294768 20118626 18648771 18754104 19255062 19642983 20101389 16942905 20583210 19812893 18644402 20501860 20434301 20452335 19499222 19090486 20137499 21071580 19690152 20405173 19254457 21047994 18977376 19833225 19638242 2422723 19850985 2862719 19996281 19073162 12112319 19551842 21167192 9163691 19426721 20492335 15175105 19427195 12771043 19256749 10737359
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 10.9416984957
MESH:D008114 Liver Neoplasms, Experimental beta-Naphthoflavone 10.0618164116
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 10.0619126423 16267830 18253720 18282651 19004024 19539802 18093689 19009564 18164116 16842330 17942915 18308698 9362446 17854601 2563599 18775883 19519916 18079962 18544905 21159647 3124819 17174075
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 10.0612151625
MESH:D008171 Lung Diseases Mustard Gas 3.4818702808 18161513
MESH:D008175 Lung Neoplasms Diethylnitrosamine 3.4620512841 20970405 21163286 6695378
MESH:D008175 Lung Neoplasms Mustard Gas 3.468781369 3148597
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 3.4619555203 11884234
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 6.1711807958 16891317 11408345 17203775
MESH:D008325 Mammary Neoplasms, Experimental Progesterone 6.1717203775 11408345
MESH:D020149 Manganese Poisoning Estradiol 4.5819453300
MESH:D008527 Medulloblastoma Tretinoin 2.8017453147
MESH:D008545 Melanoma Tretinoin 1.9516752155
MESH:D008591 Meningomyelocele Tretinoin 4.5016940565
MESH:D008607 Mental Retardation Phenytoin 3.689212184
MESH:D009137 Muscular Dystrophy, Animal Gentamicins 6.3718694830
MESH:D009190 Myelodysplastic Syndromes Tretinoin 3.1117596541
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 3.0612213967
MESH:D015428 Myocardial Reperfusion Injury Estradiol 3.3216810080
MESH:D020191 Myoclonic Epilepsies, Progressive Phenytoin 5.6017484760
MESH:D009224 Myotonia Congenita Phenytoin 5.491896199
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 2.593581430 9029167
MESH:D009369 Neoplasms 2,4,5,2',4',5'-hexachlorobiphenyl 5.628820588
MESH:D009369 Neoplasms Tretinoin 5.6216594593 16946489
MESH:D009389 Neovascularization, Pathologic Estradiol 3.8117289903
MESH:D009410 Nerve Degeneration Acrylamide 4.7311264303 12387367 12387366
MESH:D009422 Nervous System Diseases Acrylamide 5.0312164553 12507653
MESH:D009421 Nervous System Malformations Estradiol 16.7216427766 11399458
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 16.7214600291
MESH:D009421 Nervous System Malformations Tretinoin 16.729125849
MESH:D009436 Neural Tube Defects Phenytoin 7.799118846
MESH:D009436 Neural Tube Defects Tretinoin 7.799142499
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 3.3920387270
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 5.2120387270
MESH:D020258 Neurotoxicity Syndromes Chlorpyrifos 4.2015081274
MESH:D009503 Neutropenia Mustard Gas 4.0316761898 7688884
MESH:D010018 Osteomalacia Phenytoin 5.4917016548
MESH:D010051 Ovarian Neoplasms Estradiol 7.9819401270
MESH:D010051 Ovarian Neoplasms Progesterone 7.9817393432 16525653
MESH:D010051 Ovarian Neoplasms Tretinoin 7.9816936753
MESH:D010146 Pain Phenytoin 7.3215215642
MESH:D010146 Pain Tretinoin 7.3216870215
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 5.3116540662
MESH:D010190 Pancreatic Neoplasms Tretinoin 5.3115976015
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.3512520081
MESH:D010523 Peripheral Nervous System Diseases Acrylamide 5.1711510240
MESH:D011041 Poisoning Mustard Gas 3.8515727166
MESH:D017689 Polydactyly Phenytoin 5.099212184
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.6218163543
MESH:D011230 Precancerous Conditions Diethylnitrosamine 3.602563599
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 3.2711399792 11118676 11222880 11896295
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 3.9420887781
MESH:D011471 Prostatic Neoplasms Estradiol 3.0816740699
MESH:D011507 Proteinuria Gentamicins 9.7415033597
MESH:D011507 Proteinuria Tretinoin 9.7416636307
MESH:D011537 Pruritus Mustard Gas 4.1718058305
MESH:D019310 Pseudolymphoma Phenytoin 5.648603615 12752131 1419762
MESH:D011625 Pterygium Tretinoin 4.8816723453
MESH:D011658 Pulmonary Fibrosis Mustard Gas 2.9410334151 17894541 17620002 17266442 17720292
MESH:D051437 Renal Insufficiency Gentamicins 5.0715728788 17132701
MESH:D012135 Respiratory Sounds Chlorpyrifos 4.7117119214 11874814 16611668
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.9018990726
MESH:D012140 Respiratory Tract Diseases Chlorpyrifos 4.9916611668 17119214
MESH:D012173 Retinitis Gentamicins 6.3718644591
MESH:D012208 Rhabdomyosarcoma Tretinoin 4.1616283617 16116481
MESH:D012468 Salivary Gland Neoplasms Progesterone 2.8718045962
MESH:D012559 Schizophrenia marker/mechanism 18572319
MESH:D012640 Seizures Phenytoin 3.779844417 3137016 19919933 10029267 16876388 3691417 11044598 15946322
MESH:D012729 Sex Chromosome Aberrations Chlorpyrifos 6.196418539
MESH:D012871 Skin Diseases Mustard Gas 2.7316961503 15451306 12880345
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 5.6416192470
MESH:D012878 Skin Neoplasms Tretinoin 5.6416467112
MESH:D013119 Spinal Cord Injuries Progesterone 4.3615862959 16503802
MESH:D013262 Stevens-Johnson Syndrome Phenytoin 5.2320235791
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 2.4318456281
MESH:D013274 Stomach Neoplasms Tretinoin 2.4317261132
MESH:D013733 Testicular Diseases Acrylamide 5.3115864552
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 4.0012697716
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 7.317505956
MESH:D013964 Thyroid Neoplasms Tretinoin 7.3117045167 16026305
MESH:D013978 Tibial Fractures Estradiol 4.7819048282
MESH:D014062 Tongue Neoplasms Tretinoin 3.8416051514
MESH:D014376 Tuberculosis Tretinoin 3.2616040207
MESH:D002583 Uterine Cervical Neoplasms Tretinoin 3.7316129372
MESH:D014604 Uveal Neoplasms Tretinoin 4.7116752155
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.6912125929
MESH:D015837 Vestibular Diseases Gentamicins 5.5818776599
MESH:D014820 Vitiligo Tretinoin 4.1216761959
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.3515886252
MESH:D009396 Wilms Tumor Tretinoin 4.0216287080
Pathway ID Pathway Name
KEGG:04010 MAPK signaling pathway
KEGG:04722 Neurotrophin signaling pathway
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Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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