AutismKB 2.0

Annotation Detail for NTF4


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Basic Information Top
Gene Symbol:NTF4 ( GLC10,GLC1O,NT-4/5,NT4,NT5,NTF5 )
Gene Full Name: neurotrophin 4
Band: 19q13.3
Quick LinksEntrez ID:4909; OMIM: 162662; Uniprot ID:NTF4_HUMAN; ENSEMBL ID: ENSG00000167744; HGNC ID: 8024
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa04010MAPK signaling pathway
hsa04722Neurotrophin signaling pathway
No data
Pathway IDPathway Name
200128Neurotrophic factor-mediated Trk receptor signaling
200103p75(NTR)-mediated signaling
No data
No data
Related Diseases/Disorders Top
No data
No data
No data
No data
Desease Name
Glaucoma 1, open angle, 1O
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000643 Ammonium Chloride Ammonium Chloride affects the expression of NTF4 mRNAaffects expression 16483693
D001104 Arbutin Arbutin results in decreased expression of NTF4 mRNAdecreases expression 17103032
D004026 Dieldrin Dieldrin results in increased expression of NTF4 mRNAincreases expression 19130878
D009532 Nickel Nickel results in decreased expression of NTF4 mRNAdecreases expression 19130878
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000138 Acidosis Ammonium Chloride 4.1918287403
MESH:D055371 Acute Lung Injury Nickel 5.0416166738
MESH:D001321 Autistic Disorder marker/mechanism 16289943 11357950
MESH:D001943 Breast Neoplasms Dieldrin 2.9215770527 11859874
MESH:D001943 Breast Neoplasms Nickel 2.9215986119
MESH:D017449 Dermatitis, Allergic Contact Nickel 4.5017244072 17100760 19470301
MESH:D003877 Dermatitis, Contact Nickel 5.102952479
OMIM:613100 GLAUCOMA 1, OPEN ANGLE, O marker/mechanism
MESH:D015658 HIV Infections Nickel 3.9917263646
MESH:D007247 Infertility, Female Dieldrin 5.4010630421
MESH:D007249 Inflammation Nickel 3.6016166738
MESH:D008113 Liver Neoplasms Dieldrin 3.468742319 9539021
MESH:D008607 Mental Retardation marker/mechanism 11357950
MESH:D009369 Neoplasms Dieldrin 3.638820588
MESH:D010300 Parkinson Disease Dieldrin 3.6417291500 16809432 11181820 11445065 16112328
Pathway ID Pathway Name
KEGG:04010 MAPK signaling pathway
KEGG:04722 Neurotrophin signaling pathway
Pharmacogenomics Knowledge Base Top
Drug Bank Top

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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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