AutismKB 2.0

Annotation Detail for ATP2B3


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Basic Information Top
Gene Symbol:ATP2B3 ( PMCA3,PMCA3a )
Gene Full Name: ATPase, Ca++ transporting, plasma membrane 3
Band: Xq28
Quick LinksEntrez ID:492; OMIM: 300014; Uniprot ID:AT2B3_HUMAN; ENSEMBL ID: ENSG00000067842; HGNC ID: 816
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa04020Calcium signaling pathway
hsa04970Salivary secretion
hsa04972Pancreatic secretion
Pathway IDPathway Name
Hemostasis
No data
No data
No data
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000643 Ammonium Chloride Ammonium Chloride affects the expression of ATP2B3 mRNAaffects expression 16483693
D004997 Ethinyl Estradiol Ethinyl Estradiol results in decreased expression of ATP2B3 mRNAdecreases expression 15834898
D005419 Flavonoids Flavonoids results in decreased expression of ATP2B3 mRNAdecreases expression 18035473
D018038 Sodium Selenite Sodium Selenite results in decreased expression of ATP2B3 mRNAdecreases expression 18175754
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000138 Acidosis Ammonium Chloride 4.1918287403
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 4.6617505938
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 1.8814692618
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 4.0211256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 2.8915885639
MESH:D002779 Cholestasis Ethinyl Estradiol 3.1717681005 15861022 17333356 16105132 11677210 16919318 17110522
MESH:D019457 Chromosome Breakage Sodium Selenite 5.3115894690
MESH:D003920 Diabetes Mellitus Sodium Selenite 4.1516285004
MESH:D056486 Drug-Induced Liver Injury Sodium Selenite 2.3615131321
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 3.6912538720
MESH:D005234 Fatty Liver Ethinyl Estradiol 3.2415345470
MESH:D007021 Hypospadias Ethinyl Estradiol 4.3716945680 16569931
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.9212013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 2.7317937319
MESH:D007249 Inflammation Flavonoids 2.8217296493
MESH:D007333 Insulin Resistance Sodium Selenite 3.5214714311
MESH:D016393 Lymphoma, B-Cell Sodium Selenite 4.5214737004
MESH:D016584 Panic Disorder Ethinyl Estradiol 4.1511578682
MESH:D011471 Prostatic Neoplasms Sodium Selenite 3.3318760546
MESH:D011537 Pruritus Ethinyl Estradiol 3.9415861022 16919318
MESH:D013088 Spermatocele Ethinyl Estradiol 4.6616709447
MESH:D019851 Thrombophilia Ethinyl Estradiol 4.0811994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.5215669648
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 3.8014692618
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.9714671159 15869587
Pathway ID Pathway Name
KEGG:04020 Calcium signaling pathway
REACT:604 Hemostasis
KEGG:04972 Pancreatic secretion
KEGG:04970 Salivary secretion
REACT:15518 Transmembrane transport of small molecules
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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