AutismKB 2.0

Annotation Detail for NUCB2


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:NUCB2 ( NEFA )
Gene Full Name: nucleobindin 2
Band: 11p15.1
Quick LinksEntrez ID:4925; OMIM: 608020; Uniprot ID:NUCB2_HUMAN; ENSEMBL ID: ENSG00000070081; HGNC ID: 8044
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C063002 2,3-dimethoxy-1,4-naphthoquinone 2,3-dimethoxy-1,4-naphthoquinone results in decreased expression of NUCB2 mRNAdecreases expression 17547211
C016403 2,4-dinitrotoluene 2,4-dinitrotoluene affects the expression of NUCB2 mRNAaffects expression 21346803
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene affects the expression of NUCB2 mRNAaffects expression 21346803
D000082 Acetaminophen Acetaminophen affects the expression of NUCB2 mRNAaffects expression 17562736
D000643 Ammonium Chloride Ammonium Chloride affects the expression of NUCB2 mRNAaffects expression 16483693
C006632 arsenic trioxide arsenic trioxide results in decreased expression of NUCB2 mRNAdecreases expression 17547211
D002104 Cadmium Cadmium results in decreased expression of NUCB2 mRNAdecreases expression 17547211
D019256 Cadmium Chloride Cadmium Chloride results in decreased expression of NUCB2 mRNAdecreases expression 17547211
D002118 Calcium KT 5720 inhibits the reaction [NUCB2 protein results in increased import of Calcium]decreases reaction|increases import 17627999
D002857 Chromium Chromium results in decreased expression of NUCB2 mRNAdecreases expression 17547211
D016572 Cyclosporine Cyclosporine results in increased expression of NUCB2 mRNAincreases expression 20106945
D004041 Dietary Fats Dietary Fats results in increased expression of NUCB2 mRNAincreases expression 18042831
D004051 Diethylhexyl Phthalate Diethylhexyl Phthalate results in decreased expression of NUCB2 proteindecreases expression 16400681
D004128 Dimethylnitrosamine Dimethylnitrosamine results in decreased expression of NUCB2 mRNAdecreases expression 17547211
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of NUCB2 mRNAincreases expression 17942748
D004997 Ethinyl Estradiol [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of NUCB2 mRNAaffects cotreatment|increases expression 17942748
D005419 Flavonoids Flavonoids results in decreased expression of NUCB2 mRNAdecreases expression 18035473
D017313 Fenretinide Fenretinide results in increased expression of NUCB2 mRNAincreases expression 16671099
C057416 KT 5720 KT 5720 inhibits the reaction [NUCB2 protein results in increased import of Calcium]decreases reaction|increases import 17627999
D015741 Metribolone Metribolone results in increased expression of NUCB2 mRNAincreases expression 17010196
C022838 nickel chloride nickel chloride results in decreased expression of NUCB2 mRNAdecreases expression 17547211
C014707 nitrosobenzylmethylamine nitrosobenzylmethylamine results in increased expression of NUCB2 mRNAincreases expression 17616710
C041786 palm oil palm oil results in increased expression of NUCB2 mRNAincreases expression 18042831
D011192 Potassium Dichromate Potassium Dichromate results in decreased expression of NUCB2 mRNAdecreases expression 17547211
D013629 Tamoxifen Tamoxifen results in increased expression of NUCB2 mRNAincreases expression 17555576
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of NUCB2 mRNAaffects cotreatment|increases expression 17942748
D014302 Trinitrobenzenesulfonic Acid Trinitrobenzenesulfonic Acid results in increased expression of NUCB2 mRNAincreases expression 17982090
C025643 vinclozolin vinclozolin affects the expression of NUCB2 mRNAaffects expression 19015723
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Tamoxifen 4.3214745880
MESH:D000014 Abnormalities, Drug-Induced Diethylhexyl Phthalate 7.956734493
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 7.9511752688 15322242 14514962
MESH:D000138 Acidosis Ammonium Chloride 3.3318287403
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.7117505938
MESH:D000230 Adenocarcinoma arsenic trioxide 9.7519825857 11798837
MESH:D000230 Adenocarcinoma Dimethylnitrosamine 9.7516033868
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 9.7514692618
MESH:D000230 Adenocarcinoma Fenretinide 9.7510697514
MESH:D000236 Adenoma Dimethylnitrosamine 3.4219555203
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 3.1516835633
MESH:D000740 Anemia Tetrachlorodibenzodioxin 2.7511748828
MESH:D000799 Angioedema Acetaminophen 3.6110982225
MESH:D001008 Anxiety Disorders vinclozolin 3.4619015723
MESH:D001161 Arteriosclerosis Dietary Fats 9.1615238619
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 9.1611256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 2.5315885639
MESH:D050197 Atherosclerosis Cadmium 3.5115687053
MESH:D001321 Autistic Disorder Acetaminophen 1.4418445737
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 8.2816206674
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 8.2812125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.5615340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.6215746008
MESH:D001932 Brain Neoplasms Fenretinide 4.1516187019
MESH:D001943 Breast Neoplasms Chromium 2.2915986119
MESH:D001943 Breast Neoplasms Dietary Fats 2.2920435547
MESH:D001943 Breast Neoplasms Fenretinide 2.2916601279
MESH:D001943 Breast Neoplasms Tamoxifen 2.2919011961 18629630 19200415 18984771 20390343 11161223 20859285 19221464 16873071 19189212 19410462 19115204 19084267 20135344 18997820 19189210 18821012 20544844 19244106 18351453 17049068 16202921 15668708 18815881 19066611 15565566 19288272 18855134 19487384 19142967 19289846 17893378 19059307 19155303 17261762 19103187 21138602 20005174 18425577 21152245 17242785 16818667 17440819 16273361 20065188
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 2.2920435547
MESH:D002051 Burkitt Lymphoma arsenic trioxide 4.1211589617
MESH:D002277 Carcinoma Dimethylnitrosamine 7.7619555203
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 7.7616835633
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 4.2819066611
MESH:D006528 Carcinoma, Hepatocellular 2,4-dinitrotoluene 10.8916705839
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 10.8916705839
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 10.893084413
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 10.8911135700 16217749 15073043 14691202 15553829
MESH:D006528 Carcinoma, Hepatocellular Fenretinide 10.8916270382 17159502
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 10.8916924424
MESH:D002291 Carcinoma, Papillary arsenic trioxide 4.6419014326
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 3.9212490120
MESH:D002294 Carcinoma, Squamous Cell Dimethylnitrosamine 5.0016033868
MESH:D002294 Carcinoma, Squamous Cell Fenretinide 5.0016274795
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 3.4217572228
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.2418670907 16120746 18850075
MESH:D002386 Cataract Acetaminophen 2.4510977129
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 10.376135515
MESH:D002471 Cell Transformation, Neoplastic Cadmium 10.3717332340
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 10.3712371664
MESH:D018290 Cervical Intraepithelial Neoplasia Fenretinide 5.2516154183
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 2.9716835633
MESH:D002779 Cholestasis Cyclosporine 7.2219486331
MESH:D002779 Cholestasis Ethinyl Estradiol 7.2216919318 11677210 17333356 17681005 16105132 15861022 17110522
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 2.0115340226 15668235 12621046 8697196 16354765
MESH:D003092 Colitis Trinitrobenzenesulfonic Acid 4.3211698051 16867261 16782535 18023891 18200517 17936198 16804969 17991707 16474422
MESH:D003093 Colitis, Ulcerative Trinitrobenzenesulfonic Acid 3.3717276891
MESH:D015179 Colorectal Neoplasms arsenic trioxide 2.7420501625
MESH:D015179 Colorectal Neoplasms Fenretinide 2.7417273769
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 2.8714669216 17141729
MESH:D023903 Coronary Restenosis arsenic trioxide 3.9712609071
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 2.4010525206
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 2.4010048152 15322242 20055451
MESH:D003456 Cryptorchidism vinclozolin 4.1214966744
MESH:D003490 Cyanosis 2,4-dinitrotoluene 10.1418551238
MESH:D003490 Cyanosis 2,6-dinitrotoluene 10.1418551238
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 3.8815213294
MESH:D003711 Demyelinating Diseases Tamoxifen 4.1419031437
MESH:D017449 Dermatitis, Allergic Contact Potassium Dichromate 4.0916823706
MESH:D003876 Dermatitis, Atopic Diethylhexyl Phthalate 3.9416882537
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 1.6117107852
MESH:D003928 Diabetic Nephropathies Tamoxifen 3.2919279558
MESH:D056486 Drug-Induced Liver Injury 2,4-dinitrotoluene 11.2621346803 18551238
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 11.2618551238 21346803
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 11.2614550746 11421492 2444490 17522070 11743745 16109766 19739265 16081117 19416960 16781746 18713872 16177239 12540782 17906064 12153990 14725611 11461765 12958197 15619225 10915739 10774834 16485898 19923254 12705907 10663392 14986274 11739529 18071297 19420014 12392966 19164858 19085960 11529661 15968718 12594235 11287661 16227642 17562736 11834606 16393943 19370779
MESH:D056486 Drug-Induced Liver Injury Dimethylnitrosamine 11.268172417
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 11.2620420201
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 3.8719426721
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.5911462148
MESH:D050171 Dyslipidemias Dietary Fats 3.2918367378
MESH:D004487 Edema Tetrachlorodibenzodioxin 2.1811000095 12711302
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 3.6718230668 15322242 16714409
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 8.2212538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 8.2219031437
MESH:D016889 Endometrial Neoplasms Tamoxifen 2.9017893378 19155303 20544844 16202921
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 2.829294722 10568697
MESH:D004938 Esophageal Neoplasms arsenic trioxide 7.0712903497
MESH:D004938 Esophageal Neoplasms Dimethylnitrosamine 7.0717016578
MESH:D004938 Esophageal Neoplasms nitrosobenzylmethylamine 7.0716805852 16510608 15547721 15264214 15150132 15623463 15878914 16704527 15547733
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 2.8411564622
MESH:D005234 Fatty Liver arsenic trioxide 22.4615073043
MESH:D005234 Fatty Liver Cyclosporine 22.4619224547
MESH:D005234 Fatty Liver Dietary Fats 22.4619551842 17967931 19004024 18296743
MESH:D005234 Fatty Liver Ethinyl Estradiol 22.4615345470
MESH:D005234 Fatty Liver Tamoxifen 22.4614986274 19224547
MESH:D052776 Female Urogenital Diseases Tamoxifen 3.1016709447
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.2311858732
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 4.3014745880
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 3.9519069698
MESH:D005355 Fibrosis Cyclosporine 19.3212168785 12639820
MESH:D005355 Fibrosis Dietary Fats 19.3218296743
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 19.3220067830
MESH:D005355 Fibrosis Trinitrobenzenesulfonic Acid 19.3217994277
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 4.0416904648
MESH:D005756 Gastritis Acetaminophen 3.4416983495
MESH:D030342 Genetic Diseases, Inborn vinclozolin 4.7016973722
MESH:D005832 Genital Diseases, Male vinclozolin 5.0716417039
MESH:D005885 Gingival Hyperplasia Cyclosporine 3.998708960
MESH:D005909 Glioblastoma Fenretinide 3.7516187019
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.3610696789
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 2.2111294989 10048152
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.1915720958
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.1311000095
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 2.6715340226 16120746 12621046
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.818697196 16354765 15340226 18606429 16959395
MESH:D006930 Hyperalgesia Acetaminophen 2.5216870215
MESH:D006937 Hypercholesterolemia Dietary Fats 3.3921332399
MESH:D006949 Hyperlipidemias Dietary Fats 3.4021332399
MESH:D006973 Hypertension Cyclosporine 4.6610903974
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 4.6618850075 18670907
MESH:D007021 Hypospadias Ethinyl Estradiol 3.5816945680 16569931
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.2512013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 6.1617937319
MESH:D007248 Infertility, Male vinclozolin 6.1616467254
MESH:D007249 Inflammation Dietary Fats 10.9820412841
MESH:D007249 Inflammation Flavonoids 10.9817296493
MESH:D007249 Inflammation Tamoxifen 10.9819457130
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 10.9812878042 12200463
MESH:D015212 Inflammatory Bowel Diseases Trinitrobenzenesulfonic Acid 3.4918200517
MESH:D007333 Insulin Resistance Dietary Fats 2.9611836018 18457598
MESH:D007410 Intestinal Diseases Trinitrobenzenesulfonic Acid 4.3817994277
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 3.1316580747
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.2115604871
MESH:D007674 Kidney Diseases Acetaminophen 22.1912587719 15629191
MESH:D007674 Kidney Diseases Cadmium 22.1916226777 16962696 16322080
MESH:D007674 Kidney Diseases Cadmium Chloride 22.1916962696
MESH:D007674 Kidney Diseases Chromium 22.1917934191
MESH:D007674 Kidney Diseases Cyclosporine 22.1918776723 8314463 10903974
MESH:D007674 Kidney Diseases Potassium Dichromate 22.1919665454
MESH:D007680 Kidney Neoplasms 2,4-dinitrotoluene 16.2316705839
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 16.2316705839
MESH:D007680 Kidney Neoplasms Cyclosporine 16.2312371664
MESH:D007680 Kidney Neoplasms Tamoxifen 16.2318625569
MESH:D007683 Kidney Tubular Necrosis, Acute Calcium 4.8116316344
MESH:D007938 Leukemia arsenic trioxide 2.7215070760
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 3.5912560223 17077332
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 4.0816972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 3.2614633726
MESH:D007951 Leukemia, Myeloid arsenic trioxide 3.5619077051
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 2.1016968895 16467208 19850784 17050201 20471514
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 3.0711468182 16891316 17649720 17869043 16330433 19225113 19075265 11161223 9834237 15213294 16112521 16966277 17712046 15622746 15748426 12679006 12712474 12018890 15336539 17217047 16823087 19642359 19035177 16331271 17107899
MESH:D015458 Leukemia, T-Cell arsenic trioxide 4.1316882451
MESH:D007972 Leukoplakia, Oral Fenretinide 5.8116707609
MESH:D007984 Leydig Cell Tumor vinclozolin 4.5016417039
MESH:D008064 Lipidoses Tamoxifen 2.9917567588 15342952
MESH:D008103 Liver Cirrhosis Dietary Fats 2.7518296743
MESH:D008106 Liver Cirrhosis, Experimental Dimethylnitrosamine 3.3818637143 14568256 16603200 15864749 15138612 15842777 15161499 16544323 15577212 15763062 14659978 15099470 17881167 18237412 15723089 15383259 15591649 15067225 15798949 14726149 12925901 17348192 15744066 17201889 17534399 18095165 18629640 17432682 16570917 18371158 14643895 15081153 16009107 15298665 18239293 17196135 16169303 12918455 18567088 18210741 17203207 17036385 15571005 15479170 15504291 17640959 15793283 16270385 17198567 18364076 17724770 17465448 16627068 15339415 15086199 17719030 14709902 17666798 16042886 15942678 15733078 15492853 18672772 15366600 15369754
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 3.3818564211
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 3.3812878042
MESH:D008107 Liver Diseases Acetaminophen 1.5819460945 12587719 12969438 16610002 19784758 11587558 16611625 19014921
MESH:D017114 Liver Failure, Acute Acetaminophen 9.0117185352 16871587
MESH:D017114 Liver Failure, Acute Dimethylnitrosamine 9.0117457977
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 16.857678174
MESH:D008113 Liver Neoplasms arsenic trioxide 16.8514682389
MESH:D008113 Liver Neoplasms Diethylhexyl Phthalate 16.8511940454
MESH:D008113 Liver Neoplasms Dimethylnitrosamine 16.8515890375 3113478
MESH:D008113 Liver Neoplasms Tamoxifen 16.8516684651
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 16.8516984957
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 12.982876784 6135515 2876786
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 12.9820377131
MESH:D008114 Liver Neoplasms, Experimental Dimethylnitrosamine 12.9815603536 1848544 6150874
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 12.9812151625
MESH:D008133 Long QT Syndrome arsenic trioxide 3.1815213294
MESH:D008175 Lung Neoplasms arsenic trioxide 4.6311798837 19825857
MESH:D008175 Lung Neoplasms Dimethylnitrosamine 4.6319555203 16061637 11884234
MESH:D008175 Lung Neoplasms Tamoxifen 4.6318625569
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 4.6311884234 19555203
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 3.5319428831
MESH:D008325 Mammary Neoplasms, Experimental Fenretinide 5.8610697514
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 5.8611731420 19196722 16827153 19196723 14580682
MESH:D020149 Manganese Poisoning Tamoxifen 4.3219453300
MESH:D008545 Melanoma Fenretinide 3.4816270382
MESH:D008545 Melanoma Tamoxifen 3.4819393235 12393984
MESH:D018328 Melanoma, Amelanotic Tamoxifen 3.9515990972
MESH:D008546 Melanoma, Experimental Acetaminophen 3.3419513568
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.5616801185
MESH:D009062 Mouth Neoplasms Fenretinide 4.1416274795
MESH:D009101 Multiple Myeloma arsenic trioxide 2.9514977855 19417148 15949261 19549372 11468182
MESH:D009182 Mycosis Fungoides arsenic trioxide 4.4418349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 3.0116882451 16105982
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 2.8412213967
MESH:D009336 Necrosis 2,4-dinitrotoluene 9.5818551238
MESH:D009336 Necrosis 2,6-dinitrotoluene 9.5818551238 7678174
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 3.7416624393
MESH:D009362 Neoplasm Metastasis Tamoxifen 2.4619393235
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.4419410462
MESH:D009369 Neoplasms Fenretinide 3.1917353921 15958647
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 3.7719189210 19200415 19196722
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.2117954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.0918481113 19348381
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 3.0014600291
MESH:D009436 Neural Tube Defects arsenic trioxide 2.9710525206
MESH:D019636 Neurodegenerative Diseases Acetaminophen 2.6918514411
MESH:D009472 Neuronal Ceroid-Lipofuscinoses Fenretinide 5.4516303764
MESH:D009765 Obesity Dietary Fats 2.2318674790 17217161 21332399 18457598 20132043 16723640 20518802 19632207 11836018
MESH:D009784 Occupational Diseases 2,4-dinitrotoluene 8.2312819281 16049721
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 8.2316049721
MESH:D010024 Osteoporosis Calcium 3.6417882678
MESH:D010051 Ovarian Neoplasms arsenic trioxide 4.9619769630 12452020 16624393
MESH:D010051 Ovarian Neoplasms Fenretinide 4.9616133793
MESH:D010146 Pain Acetaminophen 2.2116870215
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 5.3415580305
MESH:D010190 Pancreatic Neoplasms Fenretinide 5.3415580305
MESH:D010195 Pancreatitis Trinitrobenzenesulfonic Acid 3.9917698068
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.4711578682
MESH:D010235 Paraganglioma arsenic trioxide 3.9519927285
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.0212520081
MESH:D016491 Peripheral Vascular Diseases Cadmium 5.1515687053
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.3418163543
MESH:D011230 Precancerous Conditions Cyclosporine 3.0312371664
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 8.7311118676 11399792 11896295 11222880
MESH:D011297 Prenatal Exposure Delayed Effects vinclozolin 8.7319015723 18042343 18220299
MESH:D011469 Prostatic Diseases vinclozolin 4.7018220299
MESH:D011471 Prostatic Neoplasms marker/mechanism 17013881
MESH:D011471 Prostatic Neoplasms arsenic trioxide 2.1919131511
MESH:D011471 Prostatic Neoplasms Cadmium 2.1917075824
MESH:D011471 Prostatic Neoplasms Fenretinide 2.1917024972
MESH:D011471 Prostatic Neoplasms Tamoxifen 2.1915067354
MESH:D011472 Prostatitis vinclozolin 4.7018629315
MESH:D011537 Pruritus Ethinyl Estradiol 3.0916919318 15861022
MESH:D011565 Psoriasis Cyclosporine 2.1516882103
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.6218990726
MESH:D012162 Retinal Degeneration Fenretinide 4.2316303925
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 3.7416646077
MESH:D012640 Seizures 2,4-dinitrotoluene 5.3618551238
MESH:D012640 Seizures 2,6-dinitrotoluene 5.3618551238
MESH:D012878 Skin Neoplasms Fenretinide 5.5316467112
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 5.5316192470
MESH:D013088 Spermatocele Ethinyl Estradiol 10.7916709447
MESH:D013088 Spermatocele Tamoxifen 10.7916709447
MESH:D013119 Spinal Cord Injuries Tamoxifen 3.8119457130
MESH:D013158 Splenic Diseases Dimethylnitrosamine 5.0412587719
MESH:D013274 Stomach Neoplasms arsenic trioxide 3.4117007042
MESH:D013274 Stomach Neoplasms Dimethylnitrosamine 3.4116033868
MESH:D013274 Stomach Neoplasms nitrosobenzylmethylamine 3.4117575124 12958204
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.4111994571
MESH:D013927 Thrombosis Ethinyl Estradiol 2.9615669648
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.6712697716
MESH:D013964 Thyroid Neoplasms arsenic trioxide 2.9219014326
MESH:D016171 Torsades de Pointes arsenic trioxide 3.7315213294
MESH:D001749 Urinary Bladder Neoplasms 2,4-dinitrotoluene 14.8516049721
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 14.8516049721
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 14.8520435036 12973940 11780464 12845720
MESH:D001749 Urinary Bladder Neoplasms Fenretinide 14.8516720286
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 14.8516712894 17572228 8653321
MESH:D014571 Urologic Neoplasms 2,4-dinitrotoluene 11.2210091137
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 11.2210091137
MESH:D014581 Urticaria Acetaminophen 2.7710982225
MESH:D002583 Uterine Cervical Neoplasms Fenretinide 4.3616154183
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 3.0814692618
MESH:D014605 Uveitis Cyclosporine 3.751336536
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.3612125929
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.3314671159 15869587
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.0215886252
MESH:D015430 Weight Gain Dietary Fats 3.5516723640
MESH:D014985 Xerophthalmia Cyclosporine 4.2117120751
No data
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA31826
    • No data
    Releated disease ID Related disease Name
    PA446155Precursor Cell Lymphoblastic Leukemia-Lymphoma
    No data
    Drug Bank Top

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


    Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved