AutismKB 2.0

Annotation Detail for OPCML


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Basic Information Top
Gene Symbol:OPCML ( IGLON1,OBCAM,OPCM )
Gene Full Name: opioid binding protein/cell adhesion molecule-like
Band: 11q25
Quick LinksEntrez ID:4978; OMIM: 600632; Uniprot ID:OPCM_HUMAN; ENSEMBL ID: ENSG00000183715; HGNC ID: 8143
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
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Desease Name
Ovarian cancer, somatic
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C006632 arsenic trioxide arsenic trioxide results in increased expression of OPCML mRNAincreases expression 20458559
D005419 Flavonoids Flavonoids results in increased expression of OPCML mRNAincreases expression 18035473
C025643 vinclozolin vinclozolin affects the expression of OPCML mRNAaffects expression 19015723
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000230 Adenocarcinoma arsenic trioxide 2.3611798837 19825857
MESH:D001008 Anxiety Disorders vinclozolin 4.0019015723
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 4.1516206674
OMIM:604370 BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 1 marker/mechanism
MESH:D002051 Burkitt Lymphoma arsenic trioxide 4.8611589617
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 1.9815073043 14691202 11135700 16217749 15553829
MESH:D002291 Carcinoma, Papillary arsenic trioxide 5.7419014326
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 4.5712490120
MESH:D015179 Colorectal Neoplasms arsenic trioxide 1.8720501625
MESH:D023903 Coronary Restenosis arsenic trioxide 4.7712609071
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 1.8910525206
MESH:D003456 Cryptorchidism vinclozolin 4.9314966744
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 4.6315213294
MESH:D004938 Esophageal Neoplasms arsenic trioxide 2.3912903497
MESH:D005234 Fatty Liver arsenic trioxide 3.7715073043
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 4.8516904648
MESH:D030342 Genetic Diseases, Inborn vinclozolin 5.6816973722
MESH:D005832 Genital Diseases, Male vinclozolin 6.1716417039
MESH:D007248 Infertility, Male vinclozolin 3.3216467254
MESH:D007249 Inflammation Flavonoids 2.8417296493
MESH:D007938 Leukemia arsenic trioxide 3.0115070760
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 4.2817077332 12560223
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 5.0516972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 3.7514633726
MESH:D007951 Leukemia, Myeloid arsenic trioxide 4.2419077051
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 2.1916467208 20471514 19850784 17050201 16968895
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 3.4819642359 12679006 12018890 16966277 15213294 11161223 9834237 17869043 17649720 15622746 16823087 15336539 16891316 19075265 19035177 16330433 17712046 19225113 11468182 12712474 16112521 17107899 15748426 16331271 17217047
MESH:D015458 Leukemia, T-Cell arsenic trioxide 4.9416882451
MESH:D007984 Leydig Cell Tumor vinclozolin 5.4716417039
MESH:D008113 Liver Neoplasms arsenic trioxide 2.4714682389
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 2.9820377131
MESH:D008133 Long QT Syndrome arsenic trioxide 3.6915213294
MESH:D008175 Lung Neoplasms arsenic trioxide 1.8719825857 11798837
MESH:D009101 Multiple Myeloma arsenic trioxide 3.4114977855 19417148 11468182 19549372 15949261
MESH:D009182 Mycosis Fungoides arsenic trioxide 5.5418349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 3.3616882451 16105982
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 4.5416624393
MESH:D009436 Neural Tube Defects arsenic trioxide 3.3810525206
MESH:D010051 Ovarian Neoplasms marker/mechanism
MESH:D010051 Ovarian Neoplasms arsenic trioxide 2.5116624393 12452020 19769630
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 2.6415580305
MESH:D010235 Paraganglioma arsenic trioxide 4.6919927285
MESH:D011297 Prenatal Exposure Delayed Effects vinclozolin 4.6418220299 18042343 19015723
MESH:D011469 Prostatic Diseases vinclozolin 5.6818220299
MESH:D011471 Prostatic Neoplasms arsenic trioxide 3.2019131511
MESH:D011472 Prostatitis vinclozolin 5.6818629315
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 4.5416646077
MESH:D013274 Stomach Neoplasms arsenic trioxide 1.8617007042
MESH:D013964 Thyroid Neoplasms arsenic trioxide 3.4319014326
MESH:D016171 Torsades de Pointes arsenic trioxide 4.7015213294
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 2.6112973940 20435036 12845720 11780464
No data
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA31930
    • No data
    Releated disease ID Related disease Name
    PA443319Alzheimer Disease
    Releated drug ID Related drug Name
    PA450626nicotine
    Drug Bank Top

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    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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