AutismKB 2.0

Annotation Detail for ATP5A1


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Basic Information Top
Gene Symbol:ATP5A1 ( ATP5A,ATP5AL2,ATPM,MOM2,OMR,ORM,hATP1 )
Gene Full Name: ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle
Band: 18q21.1
Quick LinksEntrez ID:498; OMIM: 164360; Uniprot ID:ATPA_HUMAN; ENSEMBL ID: ENSG00000152234; HGNC ID: 823
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa05016Huntington's disease
hsa05010Alzheimer's disease
hsa05012Parkinson's disease
hsa00190Oxidative phosphorylation
hsa01100Metabolic pathways
Pathway IDPathway Name
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncou
No data
Pathway IDPathway Name
P02721ATP synthesis
No data
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1740Alzheimer's disease
2120Rabies
No data
No data
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene affects the expression of ATP5A1 mRNAaffects expression 21346803
C472791 3-(4'-hydroxy-3'-adamantylbiphenyl-4-yl)acrylic acid 3-(4'-hydroxy-3'-adamantylbiphenyl-4-yl)acrylic acid results in decreased expression of ATP5A1 mRNAdecreases expression 12958071
D000082 Acetaminophen Acetaminophen affects the expression of ATP5A1 mRNAaffects expression 17562736
D000082 Acetaminophen Acetaminophen results in decreased expression of ATP5A1 proteindecreases expression 11752693
D000171 Acrolein Acrolein affects the metabolism of ATP5A1 proteinaffects metabolic processing 17921335
D000643 Ammonium Chloride Ammonium Chloride affects the expression of ATP5A1 mRNAaffects expression 16483693
C006632 arsenic trioxide arsenic trioxide results in decreased expression of ATP5A1 mRNAdecreases expression 15949261
C006632 arsenic trioxide arsenic trioxide results in decreased expression of ATP5A1 mRNAdecreases expression 19422848
C099555 CD 437 CD 437 results in decreased expression of ATP5A1 mRNAdecreases expression 12958071
C444299 diindolylmethane diindolylmethane inhibits the reaction [Estradiol results in increased expression of ATP5A1 mRNA]decreases reaction|increases expression 11179685
D004958 Estradiol diindolylmethane inhibits the reaction [Estradiol results in increased expression of ATP5A1 mRNA]decreases reaction|increases expression 11179685
D004958 Estradiol Estradiol results in increased expression of ATP5A1 mRNAincreases expression 11179685
D004958 Estradiol Tetrachlorodibenzodioxin inhibits the reaction [Estradiol results in increased expression of ATP5A1 mRNA]decreases reaction|increases expression 11179685
D004997 Ethinyl Estradiol Ethinyl Estradiol affects the expression of ATP5A1 mRNAaffects expression 17555576
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of ATP5A1 mRNAincreases expression 17942748
D004997 Ethinyl Estradiol [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of ATP5A1 mRNAaffects cotreatment|increases expression 17942748
D005419 Flavonoids Flavonoids results in decreased expression of ATP5A1 mRNAdecreases expression 18035473
D005996 Nitroglycerin Nitroglycerin results in decreased expression of ATP5A1 mRNAdecreases expression 12102619
C059514 resveratrol resveratrol binds to and results in decreased activity of [ATP5B protein binds to ATP5A1 protein binds to ATP5C1 protein]affects binding|decreases activity 17698806
D013629 Tamoxifen Tamoxifen affects the expression of ATP5A1 mRNAaffects expression 17555576
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin inhibits the reaction [Estradiol results in increased expression of ATP5A1 mRNA]decreases reaction|increases expression 11179685
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of ATP5A1 mRNAaffects cotreatment|increases expression 17942748
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of ATP5A1 mRNAincreases expression 17942748
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of ATP5A1 proteindecreases expression 16548065
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Tamoxifen 4.6114745880
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 2.9011752688 14514962 15322242
MESH:D000138 Acidosis Ammonium Chloride 3.6118287403
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 4.0017505938
MESH:D058186 Acute Kidney Injury resveratrol 3.8816538975
MESH:D055371 Acute Lung Injury Acrolein 4.7420525806 21297076
MESH:D000230 Adenocarcinoma arsenic trioxide 7.0811798837 19825857
MESH:D000230 Adenocarcinoma Estradiol 7.0811473722
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 7.0814692618
MESH:D000236 Adenoma resveratrol 3.3315688382
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 3.4316835633
MESH:D000544 Alzheimer Disease Acrolein 4.7117570602 14715435 15207723
MESH:D000544 Alzheimer Disease resveratrol 4.7116162502 16183991
MESH:D000740 Anemia Tetrachlorodibenzodioxin 2.9711748828
MESH:D000799 Angioedema Acetaminophen 3.9110982225
MESH:D001161 Arteriosclerosis Acrolein 10.4615014928
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 10.4611256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 7.4215885639
MESH:D001169 Arthritis, Experimental resveratrol 7.4217115116
MESH:D050197 Atherosclerosis Acrolein 7.2116037261 16126721 17363696
MESH:D050197 Atherosclerosis resveratrol 7.2116873680 17967414
MESH:D001321 Autistic Disorder Acetaminophen 1.4218445737
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 9.0616206674
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 9.0612125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.8515340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.7815746008
MESH:D002545 Brain Ischemia resveratrol 4.3317600658
MESH:D001943 Breast Neoplasms Estradiol 1.9512948864 17261762 17018787 19861407 18497071 17289903 14630087 16675129
MESH:D001943 Breast Neoplasms resveratrol 1.9516393696 17651959 17534123
MESH:D001943 Breast Neoplasms Tamoxifen 1.9517049068 17242785 15565566 17893378 21138602 16202921 17261762 18997820 19084267 19221464 19487384 11161223 20390343 16818667 19189210 19244106 20544844 19189212 19410462 20135344 19115204 18815881 15668708 18351453 18425577 19155303 21152245 19011961 19200415 18629630 19289846 20065188 16873071 19066611 19288272 16273361 19103187 18821012 20005174 18855134 17440819 19059307 18984771 19142967 20859285
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 1.9520435547
MESH:D002051 Burkitt Lymphoma arsenic trioxide 4.3611589617
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 4.5116111702
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.8216835633
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 4.5519066611
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 11.4616705839
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 11.463084413
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 11.4611135700 14691202 15553829 16217749 15073043
MESH:D006528 Carcinoma, Hepatocellular Estradiol 11.4616924424
MESH:D006528 Carcinoma, Hepatocellular resveratrol 11.4619321006 16227395
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 11.4616924424
MESH:D018827 Carcinoma, Lewis Lung resveratrol 4.6416675471
MESH:D002291 Carcinoma, Papillary arsenic trioxide 4.9419014326
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 4.1412490120
MESH:D002294 Carcinoma, Squamous Cell resveratrol 2.7216227395
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 3.6417572228
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.3818670907 16120746 18850075
MESH:D002318 Cardiovascular Diseases resveratrol 3.4915458977
MESH:D002386 Cataract Acetaminophen 2.6010977129
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 6.736135515
MESH:D002471 Cell Transformation, Neoplastic Estradiol 6.7318566989
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 3.1916835633
MESH:D002779 Cholestasis Ethinyl Estradiol 2.8917110522 16105132 17333356 15861022 17681005 11677210 16919318
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 2.1115340226 8697196 15668235 16354765 12621046
MESH:D003092 Colitis resveratrol 4.1716474422
MESH:D003110 Colonic Neoplasms resveratrol 2.4616338953
MESH:D015179 Colorectal Neoplasms Acrolein 3.6317597105
MESH:D015179 Colorectal Neoplasms arsenic trioxide 3.6320501625
MESH:D015179 Colorectal Neoplasms resveratrol 3.6316550006
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 3.0814669216 17141729
MESH:D003327 Coronary Disease resveratrol 3.7716507316
MESH:D023903 Coronary Restenosis arsenic trioxide 4.2212609071
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 2.4810525206
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 2.4815322242 10048152 20055451
MESH:D003490 Cyanosis 2,6-dinitrotoluene 4.0618551238
MESH:D003556 Cystitis Acrolein 5.4512161096
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 4.1315213294
MESH:D003711 Demyelinating Diseases Tamoxifen 4.4019031437
MESH:D003921 Diabetes Mellitus, Experimental resveratrol 3.7916873680
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 1.6717107852
MESH:D003928 Diabetic Nephropathies Estradiol 15.1819279558
MESH:D003928 Diabetic Nephropathies resveratrol 15.1816286809
MESH:D003928 Diabetic Nephropathies Tamoxifen 15.1819279558
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 6.1618551238 21346803
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 6.1614725611 15619225 12705907 11421492 11461765 2444490 18071297 16081117 11743745 19085960 11287661 19420014 16781746 19164858 11529661 11834606 19739265 16109766 19416960 12958197 10915739 16177239 11739529 12594235 12153990 19923254 12540782 15968718 18713872 16227642 14550746 17522070 10774834 17906064 10663392 14986274 19370779 17562736 16485898 12392966 16393943
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 6.1620420201
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.1619426721
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.7811462148
MESH:D004487 Edema resveratrol 6.968985016
MESH:D004487 Edema Tetrachlorodibenzodioxin 6.9612711302 11000095
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 3.9615322242 18230668 16714409
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 15.5812538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental resveratrol 15.5817872969
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 15.5819031437
MESH:D016889 Endometrial Neoplasms Estradiol 7.4518566989 19148513 11473722
MESH:D016889 Endometrial Neoplasms Tamoxifen 7.4517893378 20544844 16202921 19155303
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 3.059294722 10568697
MESH:D020345 Enterocolitis, Necrotizing resveratrol 4.8917923197
MESH:D004938 Esophageal Neoplasms arsenic trioxide 2.3212903497
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 3.0311564622
MESH:D005234 Fatty Liver arsenic trioxide 13.2915073043
MESH:D005234 Fatty Liver Ethinyl Estradiol 13.2915345470
MESH:D005234 Fatty Liver Tamoxifen 13.2919224547 14986274
MESH:D052776 Female Urogenital Diseases Tamoxifen 3.2516709447
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.5011858732
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 4.5814745880
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 4.2319069698
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 2.9920067830
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 4.3016904648
MESH:D005756 Gastritis Acetaminophen 3.7416983495
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.6610696789
MESH:D006261 Headache Nitroglycerin 5.2511554966 11284996
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 2.3411294989 10048152
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.3611000095
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 2.9316120746 12621046 15340226
MESH:D006558 Herpes Genitalis Estradiol 5.0915709030
MESH:D006561 Herpes Simplex resveratrol 4.2316876885
MESH:D019584 Hot Flashes Estradiol 3.8117088409
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 4.118697196 16959395 16354765 18606429 15340226
MESH:D006930 Hyperalgesia Acetaminophen 2.7216870215
MESH:D006937 Hypercholesterolemia resveratrol 4.0317188708
MESH:D006949 Hyperlipidemias resveratrol 4.0616873680
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 1.9118850075 18670907
MESH:D017379 Hypertrophy, Left Ventricular resveratrol 4.3317488730
MESH:D007021 Hypospadias Ethinyl Estradiol 3.8516569931 16945680
MESH:D020244 Infarction, Middle Cerebral Artery resveratrol 4.6917600658
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.4912013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 2.5017937319
MESH:D007249 Inflammation Flavonoids 12.1017296493
MESH:D007249 Inflammation resveratrol 12.1016366677
MESH:D007249 Inflammation Tamoxifen 12.1019457130
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 12.1012200463 12878042
MESH:D007251 Influenza, Human resveratrol 4.6116624496
MESH:D007333 Insulin Resistance Estradiol 2.9816393666 16627594
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 3.3616580747
MESH:D007674 Kidney Diseases Acetaminophen 10.2715629191 12587719
MESH:D007674 Kidney Diseases Acrolein 10.2712488133
MESH:D007674 Kidney Diseases Estradiol 10.2715618244
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 12.5516705839
MESH:D007680 Kidney Neoplasms Estradiol 12.5515610895
MESH:D007680 Kidney Neoplasms Tamoxifen 12.5518625569
MESH:D007938 Leukemia arsenic trioxide 2.8415070760
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 3.8212560223 17077332
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 4.3616972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 3.4514633726
MESH:D007951 Leukemia, Myeloid arsenic trioxide 3.7919077051
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 2.1420471514 17050201 16968895 16467208 19850784
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 7.8516966277 16112521 15748426 16823087 16331271 17107899 15622746 19035177 15336539 17712046 16330433 12712474 19225113 17649720 12679006 9834237 19075265 17217047 11161223 11468182 17869043 19642359 16891316 12018890 15213294
MESH:D015473 Leukemia, Promyelocytic, Acute resveratrol 7.8516087638
MESH:D015458 Leukemia, T-Cell arsenic trioxide 4.3916882451
MESH:D008064 Lipidoses Tamoxifen 3.1715342952 17567588
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 3.4514716833 14659978
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 3.4518564211
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 3.4512878042
MESH:D008107 Liver Diseases Acetaminophen 1.6311587558 12969438 16610002 19784758 12587719 16611625 19460945 19014921
MESH:D017114 Liver Failure, Acute Acetaminophen 3.2617185352 16871587
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 14.367678174
MESH:D008113 Liver Neoplasms arsenic trioxide 14.3614682389
MESH:D008113 Liver Neoplasms resveratrol 14.3619812893 19321006 19073162 20405173
MESH:D008113 Liver Neoplasms Tamoxifen 14.3616684651
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 14.3616984957
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 9.906135515 2876786 2876784
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 9.9020377131
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 9.9012151625
MESH:D008133 Long QT Syndrome arsenic trioxide 3.3715213294
MESH:D008171 Lung Diseases Acrolein 4.2311504702
MESH:D008175 Lung Neoplasms arsenic trioxide 3.4011798837 19825857
MESH:D008175 Lung Neoplasms Tamoxifen 3.4018625569
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 3.4019555203 11884234
MESH:D016393 Lymphoma, B-Cell resveratrol 4.3317088997
MESH:D008228 Lymphoma, Non-Hodgkin resveratrol 3.8914749477
MESH:D015674 Mammary Neoplasms, Animal resveratrol 10.1715688416
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 10.1719428831
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 10.1117203775 16891317 11408345 11807958
MESH:D008325 Mammary Neoplasms, Experimental resveratrol 10.118985016 11606380
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 10.1114580682 19196722 19196723 11731420 16827153
MESH:D020149 Manganese Poisoning Estradiol 12.8619453300
MESH:D020149 Manganese Poisoning Tamoxifen 12.8619453300
MESH:D008545 Melanoma resveratrol 3.4517992120
MESH:D008545 Melanoma Tamoxifen 3.4519393235 12393984
MESH:D018328 Melanoma, Amelanotic Tamoxifen 4.2315990972
MESH:D008546 Melanoma, Experimental Acetaminophen 11.1219513568
MESH:D008546 Melanoma, Experimental Acrolein 11.1210803710
MESH:D008659 Metabolic Diseases resveratrol 4.4117112576
MESH:D008708 Methemoglobinemia Nitroglycerin 4.763537620
MESH:D020326 Migraine without Aura Nitroglycerin 5.1614659530
MESH:D009101 Multiple Myeloma arsenic trioxide 7.4919549372 15949261 11468182 14977855 19417148
MESH:D009101 Multiple Myeloma resveratrol 7.4914749477 16490592 16267019 17049120 17935668 17164350
MESH:D009134 Muscular Atrophy, Spinal resveratrol 4.9217962980
MESH:D009182 Mycosis Fungoides arsenic trioxide 4.7318349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 3.1616882451 16105982
MESH:D009203 Myocardial Infarction Nitroglycerin 6.3814729435
MESH:D009203 Myocardial Infarction resveratrol 6.3817015251 17188708 16317513 16525036 16456233 17125593
MESH:D017202 Myocardial Ischemia resveratrol 9.0817015251 17125593
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 9.0812213967
MESH:D015428 Myocardial Reperfusion Injury Estradiol 3.3016810080
MESH:D009205 Myocarditis resveratrol 4.8117322642
MESH:D009336 Necrosis 2,6-dinitrotoluene 3.9118551238 7678174
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 4.0016624393
MESH:D009362 Neoplasm Metastasis Tamoxifen 2.5519393235
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.5219410462
MESH:D009369 Neoplasms Acrolein 3.5517329238
MESH:D009374 Neoplasms, Experimental resveratrol 4.048985016
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 4.0619200415 19196722 19189210
MESH:D009389 Neovascularization, Pathologic Estradiol 3.7817289903
MESH:D009393 Nephritis Acrolein 6.3512653641
MESH:D009421 Nervous System Malformations Estradiol 9.5911399458 16427766
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 9.5914600291
MESH:D009436 Neural Tube Defects arsenic trioxide 3.1310525206
MESH:D019636 Neurodegenerative Diseases Acetaminophen 14.3518514411
MESH:D019636 Neurodegenerative Diseases Acrolein 14.3511342003
MESH:D019636 Neurodegenerative Diseases resveratrol 14.3517652729
MESH:D020078 Neurogenic Inflammation resveratrol 4.4317929310
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 3.4616049721
MESH:D015663 Osteoporosis, Postmenopausal resveratrol 4.2917513867
MESH:D010051 Ovarian Neoplasms arsenic trioxide 8.0512452020 16624393 19769630
MESH:D010051 Ovarian Neoplasms CD 437 8.0517474084
MESH:D010051 Ovarian Neoplasms Estradiol 8.0519401270
MESH:D010146 Pain Acetaminophen 2.4116870215
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 2.5315580305
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.7211578682
MESH:D010235 Paraganglioma arsenic trioxide 4.1919927285
MESH:D010300 Parkinson Disease Acrolein 3.6017690948
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.3112520081
MESH:D010787 Photosensitivity Disorders Acrolein 5.8011550810
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.5918163543
MESH:D011297 Prenatal Exposure Delayed Effects resveratrol 9.7616679765
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 9.7611896295 11399792 11118676 11222880
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 3.9120887781
MESH:D011471 Prostatic Neoplasms arsenic trioxide 2.0819131511
MESH:D011471 Prostatic Neoplasms Estradiol 2.0816740699
MESH:D011471 Prostatic Neoplasms resveratrol 2.0817718901 17636462 15767336 17804756 16731767 17675339
MESH:D011471 Prostatic Neoplasms Tamoxifen 2.0815067354
MESH:D011537 Pruritus Ethinyl Estradiol 3.3615861022 16919318
MESH:D051437 Renal Insufficiency Acrolein 5.0512732208
MESH:D051436 Renal Insufficiency, Chronic resveratrol 5.6516325855
MESH:D015427 Reperfusion Injury resveratrol 3.2817058453 16314181 15827377 16317513 17520802
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.8718990726
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 4.0016646077
MESH:D012640 Seizures 2,6-dinitrotoluene 2.5518551238
MESH:D012878 Skin Neoplasms resveratrol 5.768985016 15837718
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 5.7616192470
MESH:D013088 Spermatocele Ethinyl Estradiol 11.7716709447
MESH:D013088 Spermatocele Tamoxifen 11.7716709447
MESH:D013119 Spinal Cord Injuries Tamoxifen 4.0919457130
MESH:D013274 Stomach Neoplasms arsenic trioxide 1.8617007042
MESH:D020521 Stroke Acrolein 4.5816269634
OMIM:601367 STROKE, ISCHEMIC resveratrol 4.5116321402
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.6511994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.1815669648
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.9612697716
MESH:D013964 Thyroid Neoplasms arsenic trioxide 3.1119014326
MESH:D013978 Tibial Fractures Estradiol 4.7519048282
MESH:D014062 Tongue Neoplasms resveratrol 4.2416227395
MESH:D016171 Torsades de Pointes arsenic trioxide 4.0115213294
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 12.0716049721
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 12.0712845720 20435036 12973940 11780464
MESH:D001749 Urinary Bladder Neoplasms CD 437 12.0716720286
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 12.078653321 17572228 16712894
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 4.3710091137
MESH:D014581 Urticaria Acetaminophen 3.0110982225
MESH:D002583 Uterine Cervical Neoplasms resveratrol 4.1317473185
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 9.6214692618
MESH:D014594 Uterine Neoplasms resveratrol 9.6217044934
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.6612125929
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.5714671159 15869587
MESH:D018487 Ventricular Dysfunction, Left resveratrol 4.3417488730
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.3115886252
Pathway ID Pathway Name
KEGG:05010 Alzheimer's disease
KEGG:05016 Huntington's disease
KEGG:01100 Metabolic pathways
KEGG:00190 Oxidative phosphorylation
KEGG:05012 Parkinson's disease
REACT:6305 Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA25115
    • No data
    No data
    Releated drug ID Related drug Name
    PA165291922doxorubicinol
    Drug Bank Top
    Drugbank ID Action Drug Name Description
    DB04216 - Quercetin Antioxidants
    DB07384 - 1-ACETYL-2-CARBOXYPIPERIDINE
    DB07394 - AUROVERTIN B
    DB08399 - PICEATANNOL
    DB08629 - N1-(2-AMINO-4-METHYLPENTYL)OCTAHYDRO-PYRROLO[1,2-A] PYRIMIDINE
    No data
    No data
    No data

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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