AutismKB 2.0

Annotation Detail for OPRK1


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Basic Information Top
Gene Symbol:OPRK1 ( KOR,OPRK )
Gene Full Name: opioid receptor, kappa 1
Band: 8q11.23
Quick LinksEntrez ID:4986; OMIM: 165196; Uniprot ID:OPRK_HUMAN; ENSEMBL ID: ENSG00000082556; HGNC ID: 8154
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa04080Neuroactive ligand-receptor interaction
Pathway IDPathway Name
Signaling by GPCR
No data
Pathway IDPathway Name
P00026Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
P00027Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway
No data
Related Diseases/Disorders Top
No data
No data
Desease Name
CHEMDEPENDENCY
alcohol abuse
heroin abuse
No data
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C017487 2-mercaptoacetate OPRK1 exon affects the susceptibility to 2-mercaptoacetateaffects response to substance 10802031
C523979 3-(3-dimethylamino-1-ethyl-2-methylpropyl)phenol 3-(3-dimethylamino-1-ethyl-2-methylpropyl)phenol binds to OPRK1 proteinaffects binding 17656655
D000081 Acetamides Acetamides analog binds to OPRK1 proteinaffects binding 16263278
D015081 2-Naphthylamine 2-Naphthylamine results in decreased expression of OPRK1 mRNAdecreases expression 18247414
D000643 Ammonium Chloride Ammonium Chloride affects the expression of OPRK1 mRNAaffects expression 16483693
D001464 Barium 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer inhibits the reaction [OPRK1 protein results in increased transport of Barium]decreases reaction|increases transport 12031848
D001464 Barium OPRK1 protein affects the transport of Bariumaffects transport 12031848
D001564 Benzo(a)pyrene Benzo(a)pyrene results in decreased expression of OPRK1 mRNAdecreases expression 18247414
D002713 Chlorine Chlorine results in decreased expression of OPRK1 mRNAdecreases expression 18636392
D002713 Chlorine [Ozone co-treated with Chlorine] affects the expression of OPRK1 mRNAaffects cotreatment|affects expression 18636392
D003513 Cycloheximide Cycloheximide results in increased expression of OPRK1 mRNAincreases expression 19684285
D003513 Cycloheximide [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of OPRK1 mRNAaffects cotreatment|increases expression 19684285
D019900 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer inhibits the reaction [OPRK1 protein results in increased transport of Barium]decreases reaction|increases transport 12031848
D019900 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer binds to and results in increased activity of OPRK1 proteinaffects binding|increases activity 18562623
D004399 Dynorphins Dynorphins analog binds to OPRK1 proteinaffects binding 11270320
D004399 Dynorphins Dynorphins binds to and results in increased activity of OPRK1 proteinaffects binding|increases activity 11676193
D004399 Dynorphins norbinaltorphimine inhibits the reaction [Dynorphins binds to and results in increased activity of OPRK1 protein]affects binding|decreases reaction|increases activity 11676193
D000431 Ethanol Ethanol results in decreased expression of OPRK1 mRNAdecreases expression 17934066
D000431 Ethanol fomepizole inhibits the reaction [Ethanol results in decreased expression of OPRK1 mRNA]decreases expression|decreases reaction 17934066
C010238 fomepizole fomepizole inhibits the reaction [Ethanol results in decreased expression of OPRK1 mRNA]decreases expression|decreases reaction 17934066
C106014 gedunin gedunin results in decreased expression of OPRK1 mRNAdecreases expression 17010675
C058468 ICI 199441 ICI 199441 analog binds to and results in increased activity of OPRK1 proteinaffects binding|increases activity 15863335
C058468 ICI 199441 ICI 199441 binds to and results in increased activity of OPRK1 proteinaffects binding|increases activity 15863335
D008070 Lipopolysaccharides Lipopolysaccharides results in decreased expression of OPRK1 mRNAdecreases expression 18977430
D008070 Lipopolysaccharides Lipopolysaccharides results in increased expression of OPRK1 mRNAincreases expression 18977430
D009020 Morphine Morphine inhibits the reaction [Zymosan results in decreased expression of OPRK1 mRNA]decreases expression|decreases reaction 15979727
C058380 naloxone benzoylhydrazone naloxone benzoylhydrazone binds to and results in increased activity of OPRK1 proteinaffects binding|increases activity 11676193
C058380 naloxone benzoylhydrazone norbinaltorphimine inhibits the reaction [naloxone benzoylhydrazone binds to and results in increased activity of OPRK1 protein]affects binding|decreases reaction|increases activity 11676193
D009538 Nicotine Nicotine results in decreased expression of OPRK1 mRNAdecreases expression 18247414
C051844 norbinaltorphimine norbinaltorphimine binds to and results in decreased activity of OPRK1 proteinaffects binding|decreases activity 15456805
C051844 norbinaltorphimine norbinaltorphimine inhibits the reaction [Dynorphins binds to and results in increased activity of OPRK1 protein]affects binding|decreases reaction|increases activity 11676193
C051844 norbinaltorphimine norbinaltorphimine inhibits the reaction [naloxone benzoylhydrazone binds to and results in increased activity of OPRK1 protein]affects binding|decreases reaction|increases activity 11676193
C051844 norbinaltorphimine norbinaltorphimine binds to and results in decreased activity of OPRK1 proteinaffects binding|decreases activity 16954126
10802031
D010126 Ozone Ozone results in increased expression of OPRK1 mRNAincreases expression 12763052
D010126 Ozone [Ozone co-treated with Chlorine] affects the expression of OPRK1 mRNAaffects cotreatment|affects expression 18636392
D010852 Picrotoxin Picrotoxin results in increased expression of OPRK1 mRNAincreases expression 15170462
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of OPRK1 mRNAaffects cotreatment|increases expression 19684285
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of OPRK1 mRNAincreases expression 19684285
C050414 tripterine tripterine results in decreased expression of OPRK1 mRNAdecreases expression 17010675
C111212 TRK 820 TRK 820 binds to and results in increased activity of OPRK1 proteinaffects binding|increases activity 16919318
C045444 U 69593 U 69593 binds to and results in increased activity of OPRK1 proteinaffects binding|increases activity 15456805
C045444 U 69593 U 69593 binds to and results in increased activity of OPRK1 proteinaffects binding|increases activity 16954126
D015054 Zymosan Zymosan results in decreased expression of OPRK1 mRNAdecreases expression 18977430
D015054 Zymosan Morphine inhibits the reaction [Zymosan results in decreased expression of OPRK1 mRNA]decreases expression|decreases reaction 15979727
D015054 Zymosan Zymosan results in decreased expression of OPRK1 mRNAdecreases expression 15979727
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Ethanol 7.7118926900 17676605
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 7.7111752688 15322242 14514962
MESH:D000138 Acidosis Ammonium Chloride 9.7118287403
MESH:D000138 Acidosis Ethanol 9.7111192467
MESH:D055371 Acute Lung Injury Chlorine 8.7820601635
MESH:D055371 Acute Lung Injury Lipopolysaccharides 8.7811850527 18653653
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 1.9320127859 20464547
MESH:D000236 Adenoma Benzo(a)pyrene 2.526695378
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 3.1516835633
MESH:D020268 Alcohol-Induced Disorders, Nervous System Ethanol 5.0915451039 15451040
MESH:D000544 Alzheimer Disease Nicotine 4.4616627626
MESH:D000544 Alzheimer Disease Ozone 4.4615513908
MESH:D000740 Anemia Tetrachlorodibenzodioxin 8.3311748828
MESH:D000740 Anemia Zymosan 8.3318664788
MESH:D000853 Anophthalmos Ethanol 4.5915513904
MESH:D001008 Anxiety Disorders Ethanol 3.8311141031
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 3.8519183758
MESH:D001169 Arthritis, Experimental Zymosan 3.9815142272 15188379 17659584 15944321 16872482
MESH:D001172 Arthritis, Rheumatoid Ozone 2.5115570426
MESH:D001249 Asthma Ozone 2.5716373670 17854713
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 2.8412125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.5615340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.6215746008
MESH:D002545 Brain Ischemia Morphine 4.9219211983
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 1.9417474063 20146248
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 1.9420435547
MESH:D016535 Bronchial Hyperreactivity Ozone 3.5015516495 14754758 18417511 17626835 18315731 19059883 16777450
MESH:D002056 Burns Ethanol 4.4316374292
MESH:D002100 Cachexia Ozone 4.5116183385
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.6216835633
MESH:D006528 Carcinoma, Hepatocellular Ethanol 2.3715763234 18788625 15289165
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 1.9920419170
MESH:D006332 Cardiomegaly Ethanol 6.4319332462
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 6.4318850075 18670907 16120746
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 2.9716835633
MESH:D002971 Cleft Lip Ethanol 3.4715513904
MESH:D002972 Cleft Palate Ethanol 5.6315513904
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 5.6316354765 15340226 15668235 8697196 12621046
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 2.8714669216 17141729
MESH:D019465 Craniofacial Abnormalities Ethanol 2.5611873399 15451039 15513904 19302082 10194807 15451040 11198716
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 2.5620055451 10048152 15322242
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 1.6117107852
MESH:D003967 Diarrhea 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer 8.662540324
MESH:D003967 Diarrhea Morphine 8.662540324
MESH:D056486 Drug-Induced Liver Injury Ethanol 3.7111566570
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 3.7120420201
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.5911462148
MESH:D004417 Dyspnea Chlorine 4.3920016425
MESH:D020821 Dystonic Disorders Nicotine 5.7017881519
MESH:D004487 Edema Tetrachlorodibenzodioxin 6.4211000095 12711302
MESH:D004487 Edema Zymosan 6.427907874
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 3.6715322242 16714409 18230668
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 2.829294722 10568697
MESH:D019446 Endotoxemia Lipopolysaccharides 4.1717637181 15821434 15328337
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 4.4016530937
MESH:D004938 Esophageal Neoplasms Ethanol 4.4016704527
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 2.8411564622
MESH:D005234 Fatty Liver Ethanol 3.5319236843 18620774 16409862
MESH:D005235 Fatty Liver, Alcoholic Ethanol 5.4317920746
MESH:D005310 Fetal Alcohol Syndrome Ethanol 5.0716946407 15451040 15513904 10194807
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.2311858732
MESH:D005334 Fever Lipopolysaccharides 3.829205823 11852909
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 2.7320067830
MESH:D005739 Gas Poisoning Chlorine 4.7820016425
MESH:D005756 Gastritis Ethanol 4.4615046732
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.3610696789
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 6.0520471113
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 6.0510048152 11294989
MESH:D006463 Hemolytic-Uremic Syndrome Lipopolysaccharides 4.1916366002
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.1311000095
MESH:D006505 Hepatitis Zymosan 4.4819110552
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 2.6716120746 12621046 15340226
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.8118606429 15340226 16354765 8697196 16959395
MESH:D006930 Hyperalgesia Ethanol 3.5418783367
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 1.8218670907 18850075
MESH:D007249 Inflammation Lipopolysaccharides 7.8012878042 17963957 17237260 9205823 17255318
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 7.8012878042 12200463
MESH:D007249 Inflammation Zymosan 7.8011289658 8014878
MESH:D019189 Iron Metabolism Disorders Lipopolysaccharides 4.4217255318
MESH:D043183 Irritable Bowel Syndrome Zymosan 5.6117553498
MESH:D007569 Jaw Abnormalities Ethanol 9.4415513904
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 9.4416580747
MESH:D007859 Learning Disorders Ethanol 3.9915451040
MESH:D007970 Leukopenia Lipopolysaccharides 4.4715821434
MESH:D017880 Limb Deformities, Congenital Ethanol 3.6517676605
MESH:D008103 Liver Cirrhosis Ethanol 3.2515289165
MESH:D008104 Liver Cirrhosis, Alcoholic Ethanol 4.8718295389
MESH:D008106 Liver Cirrhosis, Experimental Ethanol 3.4318166357
MESH:D008106 Liver Cirrhosis, Experimental Lipopolysaccharides 3.4312878042
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 3.4312878042
MESH:D008108 Liver Diseases, Alcoholic Ethanol 4.4317347304 17207112
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 4.0421137059 20195826
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 4.0416984957
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 1.9712151625
MESH:D008171 Lung Diseases Ozone 3.2319066396 8266340
MESH:D055370 Lung Injury Lipopolysaccharides 8.4921114838
MESH:D055370 Lung Injury Ozone 8.4920417186
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 3.2420135361 18569708 17053015 20464547 20064080 18816296 6695378 20869020 18520028
MESH:D008175 Lung Neoplasms Ozone 3.247614698 8597069
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 3.2411884234 19555203
MESH:D008569 Memory Disorders Ethanol 3.9715451040 18411066
MESH:D008679 Metaplasia Ozone 4.8710496685
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 3.0216381670
MESH:D009102 Multiple Organ Failure Zymosan 4.9915213630 12130978 15834315 18160304 17724436 15259001 10890648 10479408 15241586 12879239
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 2.8412213967
MESH:D009369 Neoplasms Benzo(a)pyrene 5.0411141357
MESH:D009369 Neoplasms Nicotine 5.0416365874
MESH:D009389 Neovascularization, Pathologic Nicotine 4.7716365874
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 3.0014600291
MESH:D010146 Pain 3-(3-dimethylamino-1-ethyl-2-methylpropyl)phenol 11.1217656655
MESH:D010146 Pain 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer 11.1218699797
MESH:D010146 Pain Morphine 11.1215275824 16273134 20225289 18699797 15215642 6776300
MESH:D010190 Pancreatic Neoplasms Ethanol 2.8912384795
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.0212520081
MESH:D010538 Peritonitis Ozone 9.6716369182
MESH:D010538 Peritonitis Zymosan 9.6718557954 17371808 18760300 15979727 14761945 19641140 19088179 18977430 15259001 17826846 11985352
MESH:D011014 Pneumonia Lipopolysaccharides 10.3411605937 12224865
MESH:D011014 Pneumonia Ozone 10.3418381685 18929643 18007984
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.3418163543
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 2.9611118676 11399792 11222880 11896295
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 3.0417292933
MESH:D011537 Pruritus TRK 820 6.6416919318
MESH:D015427 Reperfusion Injury Morphine 4.0219211983
MESH:D012120 Respiration Disorders Chlorine 4.9818579056
MESH:D012130 Respiratory Hypersensitivity Lipopolysaccharides 3.5810835634
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.6218990726
MESH:D012640 Seizures Ethanol 9.359754883
MESH:D012640 Seizures Nicotine 9.3517873105
MESH:D012640 Seizures Picrotoxin 9.358954991 8635557
MESH:D018805 Sepsis Zymosan 4.4611441115
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 5.1210029692 19755658
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 5.1216192470
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 2.472093021 20155912
MESH:D013274 Stomach Neoplasms Ethanol 2.4718456281
MESH:D013276 Stomach Ulcer Ethanol 3.339211565 16755016 9562338 11906479 17189318 17918041
MESH:D013375 Substance Withdrawal Syndrome Ethanol 4.069754883
MESH:D013921 Thrombocytopenia Lipopolysaccharides 3.9715821434
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.6712697716
OMIM:188890 TOBACCO ADDICTION, SUSCEPTIBILITY TO Nicotine 4.5616785264 16720336 11259349
MESH:D014029 Tobacco Use Disorder Nicotine 5.2217979512 18305452 18041664 15735609
MESH:D001749 Urinary Bladder Neoplasms 2-Naphthylamine 5.2011144890
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 5.2017053015
MESH:D014605 Uveitis Zymosan 5.1711006244
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.3612125929
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.0215886252
Pathway ID Pathway Name
KEGG:04080 Neuroactive ligand-receptor interaction
REACT:14797 Signaling by GPCR
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA31943
  • Releated gene ID Related gene Name
    PA30729MECP2
    Releated disease ID Related disease Name
    PA444460Heroin Dependence
    No data
    Drug Bank Top
    Drugbank ID Action Drug Name Description
    DB00193 agonist Tramadol Narcotics;Analgesics;Analgesics, Opioid
    DB00295 agonist Paregorique Narcotics;Analgesics;Opiate Agonists;Analgesics, Opioid
    DB00318 partial agonist Co-codamol Narcotics;Analgesics;Opiate Agonists;Antitussives;Analgesics, Opioid;Antitussive Agents
    DB00321 agonist Triavil Tab Adrenergic Uptake Inhibitors;Analgesics, Non-Narcotic;Antidepressive Agents, Tricyclic
    DB00327 agonist Hydromorphone Narcotics;Analgesics, Opioid
    DB00370 agonist Mirtazapine Histamine H1 Antagonists;Adrenergic alpha-Antagonists;Antidepressive Agents, Tricyclic
    DB00454 - Meperidine Narcotics;Analgesics;Adjuvants, Anesthesia;Opiate Agonists;Analgesics, Opioid;Adjuvants
    DB00497 agonist Tylox Narcotics;Opiate Agonists;Antitussives;Analgesics, Opioid
    DB00611 agonist Butorphanol Narcotics;Analgesics, Opioid;Antitussive Agents;Narcotic Antagonists
    DB00647 antagonist Propoxyphene Narcotics;Analgesics;Antitussives;Analgesics, Opioid
    DB00652 agonist Talwin Narcotics;Adjuvants, Anesthesia;Analgesics, Opioid;Narcotic Antagonists
    DB00704 antagonist Naltrexone Anti-craving Agents;Narcotic Antagonists;Depressants;Alcohol Antagonists;Opiate Antagonists
    DB00708 other Sufentanil Narcotics;Adjuvants, Anesthesia;Anesthetics, Intravenous;Opiate Agonists;Analgesics, Opioid
    DB00813 agonist Innovar Injection Narcotics;Analgesics;Adjuvants, Anesthesia;Anesthetics;Anesthetics, Intravenous;Opiate Agonists;Analgesics, Opioid;Adjuvants
    DB00825 agonist Zilactin-lip Antipruritics
    DB00836 agonist Loperamide Antidiarrheals
    DB00844 agonist Nalbuphine Narcotics;Analgesics, Opioid;Narcotic Antagonists
    DB00854 agonist Levorphanol Narcotics;Analgesics, Opioid
    DB00899 agonist Remifentanil Hypnotics and Sedatives;Anesthetics, Intravenous;Analgesics, Opioid
    DB00921 antagonist Buprenorphine Narcotics;Analgesics, Opioid;Narcotic Antagonists
    DB01183 antagonist Naloxone Antinarcotic Agents;Narcotic Antagonists;Depressants;Opiate Antagonists
    DB01209 antagonist Dezocine Analgesics, Opioid
    DB01439 agonist 3-Methylthiofentanyl Analgesics, Opioid
    DB01452 agonist Heroin Narcotics;Analgesics;Analgesics, Opioid
    DB01497 agonist Etorphine Hypnotics and Sedatives;Narcotics;Analgesics, Opioid
    DB01535 agonist Carfentanil Analgesics, Opioid
    DB01548 antagonist Diprenorphine Narcotic Antagonists
    DB01565 agonist Dihydromorphine Narcotics;Analgesics, Opioid
    DB01571 agonist 3-Methylfentanyl Hypnotics and Sedatives;Analgesics
    DB06274 antagonist Alvimopan Opiate Antagonists
    No data
    No data
    No data

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018