AutismKB 2.0

Annotation Detail for ACO2


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:ACO2 ( ACONM,MGC20605,MGC33908 )
Gene Full Name: aconitase 2, mitochondrial
Band: 22q13.2
Quick LinksEntrez ID:50; OMIM: 100850; Uniprot ID:ACON_HUMAN; ENSEMBL ID: ENSG00000100412; HGNC ID: 118
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Pathway IDPathway Name
ANARESP1-PWYrespiration (anaerobic)
PWY-5690TCA cycle variation III (eukaryotic)
Pathway IDPathway Name
hsa00630Glyoxylate and dicarboxylate metabolism
hsa00020Citrate cycle (TCA cycle)
hsa01100Metabolic pathways
Pathway IDPathway Name
Pyruvate metabolism and Citric Acid (TCA) cycle
No data
No data
Pathway IDPathway Name
500713Citric acid cycle (TCA cycle)
Related Diseases/Disorders Top
No data
Desease IDDesease Name
2053Colon cancer
2120Rabies
No data
No data
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C015802 2,6-dichloro-4-nitrophenol 2,6-dichloro-4-nitrophenol results in decreased expression of ACO2 mRNAdecreases expression 11227219
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene affects the expression of ACO2 mRNAaffects expression 21346803
C024709 2,6-di-tert-butyl-4-methylene-2,5-cyclohexadienone 2,6-di-tert-butyl-4-methylene-2,5-cyclohexadienone binds to ACO2 proteinaffects binding 16533022
C009505 4,4'-diaminodiphenylmethane 4,4'-diaminodiphenylmethane results in increased expression of ACO2 mRNAincreases expression 18648102
C035207 4-amino-2,6-dinitrotoluene 4-amino-2,6-dinitrotoluene affects the expression of ACO2 mRNAaffects expression 21346803
D000535 Aluminum Aluminum results in decreased expression of and results in decreased activity of ACO2 proteindecreases activity|decreases expression 16906525
D000535 Aluminum Aluminum promotes the reaction [Nitroprusside results in decreased activity of ACO2 protein]decreases activity|increases reaction 12470706
D000535 Aluminum Aluminum results in decreased activity of ACO2 proteindecreases activity 12470706
D000638 Amiodarone Amiodarone affects the expression of ACO2 mRNAaffects expression 19483382
D000643 Ammonium Chloride Ammonium Chloride affects the expression of ACO2 mRNAaffects expression 16483693
C006632 arsenic trioxide arsenic trioxide results in decreased expression of ACO2 proteindecreases expression 19364129
D001553 Benzbromarone Benzbromarone affects the expression of ACO2 mRNAaffects expression 19483382
D002104 Cadmium Cadmium results in decreased activity of ACO2 proteindecreases activity 17170147
D019343 Citric Acid [Citric Acid co-treated with zinc chloride] results in decreased activity of ACO2 proteinaffects cotreatment|decreases activity 16624386
D002994 Clofibrate Clofibrate affects the expression of ACO2 mRNAaffects expression 19483382
D018750 6-Cyano-7-nitroquinoxaline-2,3-dione 6-Cyano-7-nitroquinoxaline-2,3-dione inhibits the reaction [Kainic Acid results in decreased activity of ACO2 protein]decreases activity|decreases reaction 11520895
D003676 Deferoxamine Deferoxamine results in decreased expression of ACO2 proteindecreases expression 17469137
16568477
D004052 Diethylnitrosamine Diethylnitrosamine results in increased expression of ACO2 mRNAincreases expression 17942915
D004052 Diethylnitrosamine MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of ACO2 mRNA]decreases reaction|increases expression 17942915
D004317 Doxorubicin Doxorubicin results in decreased expression of ACO2 proteindecreases expression 16144979
D004317 Doxorubicin Doxorubicin results in decreased activity of ACO2 proteindecreases activity 15792986
D005001 Ethionine Ethionine affects the expression of ACO2 mRNAaffects expression 19483382
C013531 ferric ammonium citrate ferric ammonium citrate inhibits the reaction [manganese chloride results in decreased activity of ACO2 protein]decreases activity|decreases reaction 16625280
C013531 ferric ammonium citrate ferric ammonium citrate inhibits the reaction [Manganese results in decreased activity of ACO2 protein]decreases activity|decreases reaction 16625280
C013531 ferric ammonium citrate ferric ammonium citrate results in increased activity of ACO2 proteinincreases activity 16625280
D005485 Flutamide Flutamide analog results in decreased expression of ACO2 mRNAdecreases expression 17702527
D005485 Flutamide Flutamide results in decreased expression of ACO2 mRNAdecreases expression 17702527
D005947 Glucose [Glucose co-treated with Oxygen] affects the activity of ACO2 proteinaffects activity|affects cotreatment 11520895
D005947 Glucose manganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [[Glucose co-treated with Oxygen] affects the activity of ACO2 protein]affects activity|affects cotreatment|decreases reaction 11520895
D005947 Glucose manganese tetrakis-(N-ethyl-2 pyridyl) porphyrin inhibits the reaction [[Glucose co-treated with Oxygen] affects the activity of ACO2 protein]affects activity|affects cotreatment|decreases reaction 11520895
D006427 Hemin Hemin results in increased expression of ACO2 proteinincreases expression 16568477
D007501 Iron Iron inhibits the reaction [manganese chloride results in decreased activity of ACO2 protein]decreases activity|decreases reaction 9675333
D007501 Iron Iron inhibits the reaction [Manganese results in decreased activity of ACO2 protein]decreases activity|decreases reaction 9675333
D007608 Kainic Acid 6-Cyano-7-nitroquinoxaline-2,3-dione inhibits the reaction [Kainic Acid results in decreased activity of ACO2 protein]decreases activity|decreases reaction 11520895
D007608 Kainic Acid Kainic Acid results in decreased activity of ACO2 proteindecreases activity 11520895
D007608 Kainic Acid manganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [Kainic Acid results in decreased activity of ACO2 protein]decreases activity|decreases reaction 11520895
D001556 Lindane Lindane results in increased expression of ACO2 mRNAincreases expression 17785943
D008345 Manganese ferric ammonium citrate inhibits the reaction [Manganese results in decreased activity of ACO2 protein]decreases activity|decreases reaction 16625280
D008345 Manganese Manganese results in decreased activity of ACO2 proteindecreases activity 16625280
D008345 Manganese Manganese results in decreased expression of ACO2 mRNAdecreases expression 16625280
D008345 Manganese Manganese results in decreased expression of ACO2 proteindecreases expression 16625280
D008345 Manganese Iron inhibits the reaction [Manganese results in decreased activity of ACO2 protein]decreases activity|decreases reaction 9675333
D008345 Manganese Manganese results in decreased activity of ACO2 proteindecreases activity 9675333
17469137
C025340 manganese chloride ferric ammonium citrate inhibits the reaction [manganese chloride results in decreased activity of ACO2 protein]decreases activity|decreases reaction 16625280
C025340 manganese chloride manganese chloride results in decreased activity of ACO2 proteindecreases activity 16625280
C025340 manganese chloride manganese chloride results in decreased expression of ACO2 mRNAdecreases expression 16625280
C025340 manganese chloride manganese chloride results in decreased expression of ACO2 proteindecreases expression 16625280
C025340 manganese chloride Iron inhibits the reaction [manganese chloride results in decreased activity of ACO2 protein]decreases activity|decreases reaction 9675333
C025340 manganese chloride manganese chloride results in decreased activity of ACO2 proteindecreases activity 9675333
C097284 manganese(III)-tetrakis(4-benzoic acid)porphyrin manganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [[Glucose co-treated with Oxygen] affects the activity of ACO2 protein]affects activity|affects cotreatment|decreases reaction 11520895
C097284 manganese(III)-tetrakis(4-benzoic acid)porphyrin manganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [Kainic Acid results in decreased activity of ACO2 protein]decreases activity|decreases reaction 11520895
C520506 manganese tetrakis-(N-ethyl-2 pyridyl) porphyrin manganese tetrakis-(N-ethyl-2 pyridyl) porphyrin inhibits the reaction [[Glucose co-treated with Oxygen] affects the activity of ACO2 protein]affects activity|affects cotreatment|decreases reaction 11520895
D015655 1-Methyl-4-phenylpyridinium 1-Methyl-4-phenylpyridinium results in decreased activity of ACO2 proteindecreases activity 11520895
C022838 nickel chloride nickel chloride results in decreased activity of ACO2 proteindecreases activity 17018869
D009599 Nitroprusside Aluminum promotes the reaction [Nitroprusside results in decreased activity of ACO2 protein]decreases activity|increases reaction 12470706
D009599 Nitroprusside Nitroprusside results in decreased activity of ACO2 proteindecreases activity 12470706
D009853 Omeprazole Omeprazole affects the expression of ACO2 mRNAaffects expression 19483382
D010100 Oxygen [Glucose co-treated with Oxygen] affects the activity of ACO2 proteinaffects activity|affects cotreatment 11520895
D010100 Oxygen manganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [[Glucose co-treated with Oxygen] affects the activity of ACO2 protein]affects activity|affects cotreatment|decreases reaction 11520895
D010100 Oxygen manganese tetrakis-(N-ethyl-2 pyridyl) porphyrin inhibits the reaction [[Glucose co-treated with Oxygen] affects the activity of ACO2 protein]affects activity|affects cotreatment|decreases reaction 11520895
D010269 Paraquat Paraquat results in decreased activity of ACO2 proteindecreases activity 15234109
D010269 Paraquat SNCA protein inhibits the reaction [Paraquat results in decreased activity of ACO2 protein]decreases activity|decreases reaction 15234109
D010269 Paraquat Paraquat results in decreased activity of ACO2 proteindecreases activity 11520895
C023036 perfluorooctanoic acid perfluorooctanoic acid results in increased expression of ACO2 mRNAincreases expression 16221955
C006253 pirinixic acid pirinixic acid results in increased expression of ACO2 mRNAincreases expression 18445702
18301758
17950772
C006253 pirinixic acid PPARA protein promotes the reaction [pirinixic acid results in increased expression of ACO2 mRNA]increases expression|increases reaction 17950772
C006253 pirinixic acid pirinixic acid affects the expression of ACO2 mRNAaffects expression 19483382
D011441 Propylthiouracil Propylthiouracil affects the expression of ACO2 mRNAaffects expression 19483382
D012402 Rotenone Rotenone results in decreased expression of ACO2 mRNAdecreases expression 17702527
D012402 Rotenone Rotenone results in decreased activity of ACO2 proteindecreases activity 11520895
D012643 Selenium Selenium results in increased expression of ACO2 mRNAincreases expression 19244175
D012645 Selenomethionine Selenomethionine affects the expression of ACO2 mRNAaffects expression 17222674
C009250 sevoflurane sevoflurane affects the expression of ACO2 mRNAaffects expression 15967596
D013853 Thioacetamide Thioacetamide affects the expression of ACO2 mRNAaffects expression 19483382
D014810 Vitamin E Vitamin E results in increased expression of ACO2 mRNAincreases expression 19244175
D015032 Zinc Zinc binds to ACO2 proteinaffects binding 15913554
C016837 zinc chloride [Citric Acid co-treated with zinc chloride] results in decreased activity of ACO2 proteinaffects cotreatment|decreases activity 16624386
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced 4-amino-2,6-dinitrotoluene 3.477525203
MESH:D000138 Acidosis Ammonium Chloride 3.0718287403
MESH:D000169 Acrodermatitis Zinc 4.9116889938 17190629 17202136
MESH:D055371 Acute Lung Injury Oxygen 7.7416759491
MESH:D055371 Acute Lung Injury pirinixic acid 7.7418653653
MESH:D000230 Adenocarcinoma arsenic trioxide 4.0819825857 11798837
MESH:D000230 Adenocarcinoma Doxorubicin 4.0817418594
MESH:D000236 Adenoma 4,4'-diaminodiphenylmethane 5.683712494
MESH:D000236 Adenoma Diethylnitrosamine 5.6810737359 6695378
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 8.4817620307 16434500 19052882 19061943 18056438 17162532
MESH:D018248 Adenoma, Liver Cell pirinixic acid 8.4816434500
MESH:D000382 Agricultural Workers' Diseases Lindane 7.3712661182
MESH:D000382 Agricultural Workers' Diseases Paraquat 7.3711874814
MESH:D000419 Albuminuria Doxorubicin 4.0821441931
MESH:D019896 alpha 1-Antitrypsin Deficiency Iron 5.1616640825
MESH:D000544 Alzheimer Disease Aluminum 6.1817662457 10721010
MESH:D000544 Alzheimer Disease Iron 6.1816563566 16640825
MESH:D000544 Alzheimer Disease Zinc 6.1816325427 17119284 16580781 16410023
MESH:D000740 Anemia Iron 3.9516434484 16566752
MESH:D018798 Anemia, Iron-Deficiency Iron 4.2217147795 16569441 17375513 17162259 17163184
MESH:D000755 Anemia, Sickle Cell Zinc 4.4416916123
MESH:D000756 Anemia, Sideroblastic Iron 15.3716910769
MESH:D000756 Anemia, Sideroblastic Manganese 15.3716910769
MESH:D000756 Anemia, Sideroblastic manganese chloride 15.3716910769
MESH:D000860 Anoxia Oxygen 4.5720872349
MESH:D001145 Arrhythmias, Cardiac Amiodarone 7.8418057881 18218290 20041841
MESH:D001145 Arrhythmias, Cardiac Iron 7.8416604332
MESH:D001249 Asthma Zinc 2.7917085522
MESH:D001260 Ataxia Telangiectasia Iron 4.9615336622
MESH:D050197 Atherosclerosis Cadmium 9.5215687053
MESH:D050197 Atherosclerosis Iron 9.5216640825 16632123
MESH:D050197 Atherosclerosis Oxygen 9.5216391483
MESH:D001281 Atrial Fibrillation Amiodarone 3.5419698954 18651412
MESH:D001321 Autistic Disorder Iron 2.8517352947
MESH:D001424 Bacterial Infections Iron 4.7116640825
MESH:D001660 Biliary Tract Diseases 4,4'-diaminodiphenylmethane 4.5211289319 1440618
MESH:D001778 Blood Coagulation Disorders Amiodarone 49.6219483382
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 49.6216206674
MESH:D001778 Blood Coagulation Disorders Benzbromarone 49.6219483382
MESH:D001778 Blood Coagulation Disorders Clofibrate 49.6219483382
MESH:D001778 Blood Coagulation Disorders Ethionine 49.6219483382
MESH:D001778 Blood Coagulation Disorders Omeprazole 49.6219483382
MESH:D001778 Blood Coagulation Disorders pirinixic acid 49.6219483382
MESH:D001778 Blood Coagulation Disorders Propylthiouracil 49.6219483382
MESH:D001778 Blood Coagulation Disorders Thioacetamide 49.6219483382
MESH:D019046 Bone Marrow Neoplasms Doxorubicin 4.2014601052
MESH:D001930 Brain Injuries Nitroprusside 9.9914637104
MESH:D001930 Brain Injuries Zinc 9.9917109824
MESH:D001932 Brain Neoplasms Doxorubicin 3.3917150277
MESH:D001943 Breast Neoplasms Deferoxamine 2.2215993339
MESH:D001943 Breast Neoplasms Diethylnitrosamine 2.2217474063
MESH:D001943 Breast Neoplasms Doxorubicin 2.2219526202 16595493 18695136 15634643 15136595 15692762 16264153 17426702 17983394 16826403 16115903 16935488 18628466 16322301 18382427 15567936 17369602 15939500 15668708 15993339 18234424 16096432 15994142 11325840
MESH:D001943 Breast Neoplasms Lindane 2.2214688026
MESH:D001943 Breast Neoplasms Oxygen 2.2217263869
MESH:D002051 Burkitt Lymphoma arsenic trioxide 3.8811589617
MESH:D002252 Carbon Tetrachloride Poisoning Vitamin E 3.4616050911
MESH:D002276 Carcinoid Tumor Doxorubicin 4.3116051944
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 12.5516705839
MESH:D006528 Carcinoma, Hepatocellular 4,4'-diaminodiphenylmethane 12.553581430 7296757
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 12.5511135700 16217749 14691202 15073043 15553829
MESH:D006528 Carcinoma, Hepatocellular Benzbromarone 12.551701930
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 12.5520007298 19171122 17162532 17428255 19418558 11831363 16830150 19519916 18665156 19822196 20214788 18785209 16502159 16807293 16328049 20935162 19208518 16288022 19383236 17138121 18056438 16779866 20432363 19394651 10737359 17761372 18971187 3581430 20101231 21159647 18691550 17173139 16698587 19335982 16540662 17978847 16935385 20084675 20727157 18506893 19107877 18393292 20512989 18788625 16569478 19701751 18978308 19919837 20524982 16878318 16681979 19052882 18494052 10672840 20514400 19539802 18210153 17055752 3084413
MESH:D006528 Carcinoma, Hepatocellular Doxorubicin 12.5516023760 16234567 18059187 17876044
MESH:D006528 Carcinoma, Hepatocellular Thioacetamide 12.5517997003
MESH:D002291 Carcinoma, Papillary arsenic trioxide 4.3819014326
MESH:D002292 Carcinoma, Renal Cell 4,4'-diaminodiphenylmethane 5.727296757
MESH:D002292 Carcinoma, Renal Cell Doxorubicin 5.7216201981 1485588
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 3.6912490120
MESH:D002294 Carcinoma, Squamous Cell Doxorubicin 4.466189445
MESH:D002294 Carcinoma, Squamous Cell Zinc 4.4616543248
MESH:D009202 Cardiomyopathies Doxorubicin 7.0716612575 15811867 17974986 16278810 17382496 16109756 17924179 16952015 17007740 17928571 17329180 15505089 15476868 16269455 16364871 16731534 16455267 18627295 17519947 16651473 16242529 17351982 17131338 15792986 17308081
MESH:D009202 Cardiomyopathies Iron 7.0716640825
MESH:D002311 Cardiomyopathy, Dilated Amiodarone 8.5415710769 19225199
MESH:D002311 Cardiomyopathy, Dilated Doxorubicin 8.5416243910 17334414
MESH:D002311 Cardiomyopathy, Dilated Iron 8.5416604332
MESH:D002318 Cardiovascular Diseases Zinc 3.3216936243
MESH:D002341 Carotid Artery Thrombosis Amiodarone 4.6018974383
MESH:D002386 Cataract 4-amino-2,6-dinitrotoluene 3.3314694615
MESH:D002418 Cattle Diseases Citric Acid 5.761108409
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 17.486135515
MESH:D002471 Cell Transformation, Neoplastic 4,4'-diaminodiphenylmethane 17.487505956
MESH:D002471 Cell Transformation, Neoplastic Cadmium 17.4817332340
MESH:D002471 Cell Transformation, Neoplastic Clofibrate 17.481399818
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 17.482727394 17174075 21159647 7505956
MESH:D002637 Chest Pain Omeprazole 4.6115447763
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 8.3719052882
MESH:D018281 Cholangiocarcinoma Thioacetamide 8.3718291259
MESH:D002779 Cholestasis 4,4'-diaminodiphenylmethane 6.639022650 19486331
MESH:D002779 Cholestasis pirinixic acid 6.6319176532
MESH:D003092 Colitis Selenium 3.3117936198
MESH:D003110 Colonic Neoplasms Iron 2.8016640825
MESH:D015179 Colorectal Neoplasms arsenic trioxide 2.4620501625
MESH:D015179 Colorectal Neoplasms Doxorubicin 2.4618259882 18802399
MESH:D000013 Congenital Abnormalities 4-amino-2,6-dinitrotoluene 3.7515095906
MESH:D023903 Coronary Restenosis arsenic trioxide 3.7212609071
MESH:D003371 Cough Citric Acid 5.709413022
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 3.5610525206
MESH:D019465 Craniofacial Abnormalities Vitamin E 3.5619769572
MESH:D019465 Craniofacial Abnormalities Zinc 3.5619302082
MESH:D003490 Cyanosis 2,6-dinitrotoluene 3.5418551238
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 3.6515213294
MESH:D017449 Dermatitis, Allergic Contact 4,4'-diaminodiphenylmethane 2.3612868966 8970840 8156756 11298694 2524372 11906362 18759878 14531868
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.1818249437
MESH:D003877 Dermatitis, Contact 4,4'-diaminodiphenylmethane 3.043621924 2952479
MESH:D003920 Diabetes Mellitus Iron 8.2716640825 16604332
MESH:D003920 Diabetes Mellitus Zinc 8.2716479319
MESH:D003922 Diabetes Mellitus, Type 1 Iron 3.1916506275
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 4.2720387270
MESH:D003924 Diabetes Mellitus, Type 2 Iron 4.2716506275
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 19.2221346803 18551238
MESH:D056486 Drug-Induced Liver Injury 4,4'-diaminodiphenylmethane 19.229653073 7440962 6482804 6679447 9022650 16192314 8291058 9328219 18648102 1440618 18692083 18289764 11289319
MESH:D056486 Drug-Induced Liver Injury 4-amino-2,6-dinitrotoluene 19.2221346803
MESH:D056486 Drug-Induced Liver Injury Amiodarone 19.2215265979 18218290
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 19.2219107877
MESH:D056486 Drug-Induced Liver Injury Doxorubicin 19.2217416283
MESH:D056486 Drug-Induced Liver Injury Selenium 19.2215131321
MESH:D056486 Drug-Induced Liver Injury Thioacetamide 19.2212963478
MESH:D004362 Drug Toxicity Doxorubicin 3.3118602426
MESH:D004381 Duodenal Ulcer Omeprazole 3.8716613094 17151854 21218061 15991576
MESH:D050171 Dyslipidemias Clofibrate 3.7116707586
MESH:D004417 Dyspnea Oxygen 4.3420016425
MESH:C538011 Eales disease Vitamin E 4.219068938
MESH:D004487 Edema perfluorooctanoic acid 5.5712083418 17259670
MESH:D004487 Edema pirinixic acid 5.5712083418
MESH:D016889 Endometrial Neoplasms Doxorubicin 3.1317359293
MESH:D004716 Endometritis Citric Acid 6.241108409
MESH:D004719 Endomyocardial Fibrosis Doxorubicin 4.6618037988
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 4.6216302075
MESH:D004938 Esophageal Neoplasms 4,4'-diaminodiphenylmethane 6.453581430
MESH:D004938 Esophageal Neoplasms arsenic trioxide 6.4512903497
MESH:D004938 Esophageal Neoplasms Zinc 6.4516543248
MESH:D005218 Fat Necrosis Thioacetamide 5.2216456712
MESH:D005234 Fatty Liver Amiodarone 25.0914986274
MESH:D005234 Fatty Liver arsenic trioxide 25.0915073043
MESH:D005234 Fatty Liver Clofibrate 25.0919224547
MESH:D005234 Fatty Liver Diethylnitrosamine 25.0921071580 20387270
MESH:D005234 Fatty Liver Iron 25.0916640825
MESH:D005234 Fatty Liver pirinixic acid 25.0920131406 19236843
MESH:D005350 Fibroma 4,4'-diaminodiphenylmethane 4.526705139
MESH:D018222 Fibromatosis, Aggressive Doxorubicin 4.1019069698
MESH:D005621 Friedreich Ataxia Iron 4.9516604332 16640825
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 3.8016904648
MESH:D005739 Gas Poisoning Oxygen 4.7220016425
MESH:D005756 Gastritis Zinc 4.3017241300
MESH:D005909 Glioblastoma Doxorubicin 6.4917150277
MESH:D005909 Glioblastoma Manganese 6.4917043766
MESH:D005911 Gliosis Paraquat 4.6711124998
MESH:D006042 Goiter 4,4'-diaminodiphenylmethane 3.597505956
MESH:D006130 Growth Disorders Zinc 3.6417217573
MESH:D006258 Head and Neck Neoplasms Doxorubicin 3.1915692506
MESH:D006330 Heart Defects, Congenital Vitamin E 2.7216080930
MESH:D006331 Heart Diseases Doxorubicin 3.1416495754 16707910 18006777 18674790 17875725 16330681 16244372 12587719 16244371 17888722 16144979 14766674 16879835
MESH:D006333 Heart Failure Doxorubicin 14.3317481944
MESH:D006333 Heart Failure pirinixic acid 14.3320558911
MESH:D006333 Heart Failure Selenium 14.3317162251
MESH:D006333 Heart Failure Zinc 14.3317162251
MESH:D006335 Heart Injuries Zinc 5.2717074742
MESH:D016481 Helicobacter Infections Zinc 4.0817241300
MESH:D006394 Hemangiosarcoma Doxorubicin 3.4715692506
MESH:D006432 Hemochromatosis Iron 4.1317236123 17053826 16640825 16574947 16604332 17255318
MESH:D006486 Hemosiderosis Iron 4.7216604332
MESH:D006501 Hepatic Encephalopathy Thioacetamide 4.1418665440 17276928 15929193
MESH:D006505 Hepatitis 4,4'-diaminodiphenylmethane 7.926705139
MESH:D006505 Hepatitis Thioacetamide 7.9216456712
MESH:D006525 Hepatitis, Viral, Human Iron 4.9716640825
MESH:D006527 Hepatolenticular Degeneration Iron 9.7217182432
MESH:D006527 Hepatolenticular Degeneration Zinc 9.7217276780
MESH:D006529 Hepatomegaly Amiodarone 16.8915265979
MESH:D006529 Hepatomegaly Iron 16.8916890145
MESH:D006529 Hepatomegaly perfluorooctanoic acid 16.893609246
MESH:D006529 Hepatomegaly pirinixic acid 16.8919772884 18467677 16221962 19176532
MESH:D006548 Hernia, Diaphragmatic Vitamin E 2.5216863852 16490937
MESH:D015658 HIV Infections Iron 3.4016597321
MESH:D006689 Hodgkin Disease Doxorubicin 3.0118501091 15147373 17606976
MESH:D019584 Hot Flashes Vitamin E 3.4814716179
MESH:D006930 Hyperalgesia perfluorooctanoic acid 3.4712083418
MESH:D017588 Hyperandrogenism Flutamide 4.9615356085
MESH:D006937 Hypercholesterolemia Amiodarone 3.449751232 8137927
MESH:D006943 Hyperglycemia pirinixic acid 2.7620558911
MESH:D006965 Hyperplasia 4,4'-diaminodiphenylmethane 3.4615034207
MESH:D007006 Hypogonadism Iron 4.0516640825
MESH:D007037 Hypothyroidism Amiodarone 16.7518020914 17991464
MESH:D007037 Hypothyroidism Iron 16.7516640825
MESH:D007037 Hypothyroidism Propylthiouracil 16.7518031379 8137927
MESH:D007248 Infertility, Male Paraquat 2.934850670
MESH:D007249 Inflammation Aluminum 7.0816052892
MESH:D007249 Inflammation Diethylnitrosamine 7.0818785209
MESH:D007249 Inflammation perfluorooctanoic acid 7.0812083418
MESH:D007251 Influenza, Human Selenium 9.3116624496
MESH:D007251 Influenza, Human Vitamin E 9.3116624496
MESH:D007333 Insulin Resistance pirinixic acid 2.3116306350
MESH:D019189 Iron Metabolism Disorders Iron 4.5917163184
MESH:D007511 Ischemia Zinc 4.1616584753
MESH:D007565 Jaundice 4,4'-diaminodiphenylmethane 4.528074119 9022650
MESH:D007674 Kidney Diseases Cadmium 12.1216962696 16226777 16322080
MESH:D007674 Kidney Diseases Doxorubicin 12.1216775033 15369732 15699352
MESH:D007674 Kidney Diseases Vitamin E 12.1212488133
MESH:D007674 Kidney Diseases Zinc 12.1216960431
MESH:D007676 Kidney Failure, Chronic Doxorubicin 14.2416707910
MESH:D007676 Kidney Failure, Chronic Selenium 14.2416518626
MESH:D007676 Kidney Failure, Chronic Zinc 14.2416518626
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 6.0516705839
MESH:D007680 Kidney Neoplasms 4,4'-diaminodiphenylmethane 6.056582329
MESH:D007859 Learning Disorders sevoflurane 4.3019212262
MESH:D016773 Leishmaniasis, Cutaneous Omeprazole 3.7019248655
MESH:D007938 Leukemia arsenic trioxide 2.5815070760
MESH:D004915 Leukemia, Erythroblastic, Acute Doxorubicin 4.6616085563
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 3.3612560223 17077332
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 3.8216972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 3.0614633726
MESH:D007951 Leukemia, Myeloid arsenic trioxide 3.3319077051
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 4.0520471514 16968895 16467208 19850784 17050201
MESH:D015470 Leukemia, Myeloid, Acute Deferoxamine 4.0520368581
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 2.8916112521 12679006 19225113 16331271 17649720 15748426 16823087 12018890 11161223 15622746 15213294 17869043 16966277 17217047 16891316 15336539 19075265 12712474 11468182 19035177 17107899 16330433 17712046 9834237 19642359
MESH:D015458 Leukemia, T-Cell arsenic trioxide 3.8916882451
MESH:D020961 Lewy Body Disease Iron 4.9516563566
MESH:D007984 Leydig Cell Tumor perfluorooctanoic acid 4.748812269
MESH:D008064 Lipidoses Amiodarone 3.1615342952 17567588
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 6.0018665156 18407596 20032147 19638242 18522880
MESH:D008103 Liver Cirrhosis Iron 6.0016640825
MESH:D008105 Liver Cirrhosis, Biliary 4,4'-diaminodiphenylmethane 2.889327722 15034207
MESH:D008106 Liver Cirrhosis, Experimental Doxorubicin 4.4016439617 16595196
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 4.4015474484
MESH:D008106 Liver Cirrhosis, Experimental Thioacetamide 4.4016511523 18395095 12175628 15288473 12557150 18263696 16097051 12679928 18615449 15078482 15465738 14739098 16343077 17127702 10677585 12531686 12891558 11682029 18606216 18416461 15288472 11481614 17355460 16098781 16489207 15075984 17292413 15334695 15362042 16126171 17050028 18458672 12085344 16248980 18380797 15095483 11172339 17629604 15158331 18032466 15716488 15474484 18031379 18295389 15316131
MESH:D008106 Liver Cirrhosis, Experimental Vitamin E 4.4016169303
MESH:D008107 Liver Diseases Diethylnitrosamine 8.3017034775
MESH:D008107 Liver Diseases Hemin 8.3017173083
MESH:D008107 Liver Diseases Lindane 8.301715830
MESH:D008107 Liver Diseases Thioacetamide 8.3016337175 18374380 15158337
MESH:D008108 Liver Diseases, Alcoholic Iron 4.5316737972 17207112
MESH:D017114 Liver Failure, Acute Thioacetamide 3.8912479984 15313186 17276928 15633222
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 15.277678174
MESH:D008113 Liver Neoplasms arsenic trioxide 15.2714682389
MESH:D008113 Liver Neoplasms Diethylnitrosamine 15.2721278145 20101389 19426721 21071580 19499222 19996281 18644402 2422723 18754104 19427195 18977376 19254457 19638242 19090486 19690152 15175105 20492335 18648771 20452335 20118626 20405173 19642983 19812893 20501860 10737359 21167192 19073162 20434301 19256749 19850985 12771043 19551842 9163691 19294768 12112319 16942905 20137499 20583210 19833225 19255062 21047994 15885732 2862719 18978307
MESH:D008113 Liver Neoplasms Iron 15.2716640825 20302851
MESH:D008113 Liver Neoplasms perfluorooctanoic acid 15.2714757943 18709148
MESH:D008113 Liver Neoplasms pirinixic acid 15.2720007298 16377806 15890375
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 15.302876786 6135515 2876784
MESH:D008114 Liver Neoplasms, Experimental 4,4'-diaminodiphenylmethane 15.303712494 6587162 1399818 598648
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 15.3020377131
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 15.3018308698 19009564 19519916 16267830 18253720 19539802 18164116 18544905 21159647 3124819 9362446 18079962 2563599 17942915 18282651 18775883 17174075 18093689 16842330 19004024 19126423 17854601
MESH:D008114 Liver Neoplasms, Experimental Doxorubicin 15.3017085340 16842330
MESH:D008133 Long QT Syndrome Amiodarone 6.9511989578 15350150 17391786
MESH:D008133 Long QT Syndrome arsenic trioxide 6.9515213294
MESH:D008171 Lung Diseases Aluminum 10.6216052892
MESH:D008171 Lung Diseases Amiodarone 10.6212587719
MESH:D008171 Lung Diseases Vitamin E 10.6216863852
MESH:D017563 Lung Diseases, Interstitial Amiodarone 3.9818516814
MESH:D055370 Lung Injury Oxygen 4.0418339021
MESH:D008175 Lung Neoplasms arsenic trioxide 5.8219825857 11798837
MESH:D008175 Lung Neoplasms Diethylnitrosamine 5.826695378 21163286 20512841 20970405
MESH:D008175 Lung Neoplasms Doxorubicin 5.8217418594 6189445
MESH:D008175 Lung Neoplasms Iron 5.8216640825
MESH:D008175 Lung Neoplasms Vitamin E 5.8211062179
MESH:D008223 Lymphoma Doxorubicin 3.1116098063
MESH:D008228 Lymphoma, Non-Hodgkin Doxorubicin 3.3917654614
MESH:D016399 Lymphoma, T-Cell Doxorubicin 4.0915621674
MESH:D008268 Macular Degeneration Iron 3.7016640825
MESH:D008325 Mammary Neoplasms, Experimental Doxorubicin 8.2415458769
MESH:D008325 Mammary Neoplasms, Experimental Selenium 8.2415318939
MESH:D008325 Mammary Neoplasms, Experimental Zinc 8.2412773700
MESH:D020149 Manganese Poisoning Manganese 5.0216551646 16568477 19453300
MESH:D008545 Melanoma Doxorubicin 3.5216827129
MESH:D008545 Melanoma Glucose 3.5214993021
MESH:D008569 Memory Disorders sevoflurane 4.2919212262
MESH:D008654 Mesothelioma Doxorubicin 5.5717638057
MESH:D008654 Mesothelioma Selenium 5.5715107826
MESH:D028361 Mitochondrial Diseases Doxorubicin 4.0615792986
MESH:D009069 Movement Disorders Manganese 4.5616551646
MESH:D052016 Mucositis Doxorubicin 4.3017415656
MESH:D009101 Multiple Myeloma arsenic trioxide 2.7611468182 14977855 19549372 19417148 15949261
MESH:D020528 Multiple Sclerosis, Chronic Progressive Aluminum 12.8517086897
MESH:D020528 Multiple Sclerosis, Chronic Progressive Iron 12.8517086897
MESH:D020529 Multiple Sclerosis, Relapsing-Remitting Aluminum 5.8817086897
MESH:D009135 Muscular Diseases pirinixic acid 3.0316239165
MESH:D009181 Mycoses Amiodarone 11.4912754197 17974566
MESH:D009181 Mycoses Iron 11.4916640825
MESH:D009182 Mycosis Fungoides arsenic trioxide 4.1718349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 2.8516105982 16882451
MESH:D009203 Myocardial Infarction Doxorubicin 4.9715857846 19429709
MESH:D009203 Myocardial Infarction pirinixic acid 4.9719151258
MESH:D017202 Myocardial Ischemia Iron 4.0616604332
MESH:D015428 Myocardial Reperfusion Injury Iron 7.3616604332
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 7.3616411023
MESH:D009336 Necrosis 2,6-dinitrotoluene 3.3818551238 7678174
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 3.5016624393
MESH:D009362 Neoplasm Metastasis 4,4'-diaminodiphenylmethane 8.253581430
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 8.253581430 9029167
MESH:D009362 Neoplasm Metastasis Doxorubicin 8.2518259882
MESH:D009369 Neoplasms Lindane 4.4212807735 16818664
MESH:D009369 Neoplasms pirinixic acid 4.4217405874
MESH:D009401 Nephrosis Doxorubicin 4.2916899518 16636307
MESH:D009404 Nephrotic Syndrome Doxorubicin 8.3815640375 16889571
MESH:D009404 Nephrotic Syndrome Iron 8.3817178036
MESH:D009410 Nerve Degeneration 1-Methyl-4-phenylpyridinium 17.0117433543
MESH:D009410 Nerve Degeneration Manganese 17.0116551646
MESH:D009410 Nerve Degeneration Paraquat 17.0116893418
MESH:D009410 Nerve Degeneration Rotenone 17.0117356569 18619942 15790535
MESH:D009436 Neural Tube Defects 4,4'-diaminodiphenylmethane 6.166679447
MESH:D009436 Neural Tube Defects arsenic trioxide 6.1610525206
MESH:D009447 Neuroblastoma Doxorubicin 3.0015555623
MESH:D019636 Neurodegenerative Diseases 1-Methyl-4-phenylpyridinium 12.1116353238
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 12.1120387270
MESH:D019636 Neurodegenerative Diseases Iron 12.1117296847 16604332
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 4.6220387270
MESH:D052556 Niemann-Pick Disease, Type C Clofibrate 10.489802331
MESH:D052556 Niemann-Pick Disease, Type C perfluorooctanoic acid 10.489802331
MESH:D009765 Obesity pirinixic acid 1.6820558911
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 12.7116049721
MESH:D009784 Occupational Diseases 4,4'-diaminodiphenylmethane 12.714026338 6482804
MESH:D009784 Occupational Diseases 4-amino-2,6-dinitrotoluene 12.7114694615
MESH:D009902 Optic Neuritis 4,4'-diaminodiphenylmethane 4.523988306
MESH:D010003 Osteoarthritis Iron 3.6616640825
MESH:D010024 Osteoporosis Iron 3.5516648989 16640825
MESH:D012516 Osteosarcoma Doxorubicin 3.7215930896
MESH:D010051 Ovarian Neoplasms arsenic trioxide 2.2519769630 16624393 12452020
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 4.6215580305
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 4.6216540662
MESH:D010212 Papilloma 4,4'-diaminodiphenylmethane 7.897296757
MESH:D010212 Papilloma Iron 7.8912065085
MESH:D010235 Paraganglioma arsenic trioxide 3.7119927285
MESH:D020447 Parasomnias Iron 5.5217352947
MESH:D010300 Parkinson Disease 1-Methyl-4-phenylpyridinium 14.1917433543
MESH:D010300 Parkinson Disease Iron 14.1916563566 16640825
MESH:D010300 Parkinson Disease Manganese 14.1911181820
MESH:D010300 Parkinson Disease Paraquat 14.1911124998 15824117 11445065 11181820 12911755 16140633 16510128 15451049
MESH:D010300 Parkinson Disease Rotenone 14.1919114014 15451049 11535288 18191903 19232380 16140633 16412576 18619942 11445065
MESH:D010302 Parkinson Disease, Secondary Paraquat 3.9616190885
MESH:D020734 Parkinsonian Disorders Manganese 8.1016140633
MESH:D020734 Parkinsonian Disorders Rotenone 8.1018197244 15927086 15795934 15574749
MESH:D016491 Peripheral Vascular Diseases Cadmium 4.8915687053
MESH:D010787 Photosensitivity Disorders 4,4'-diaminodiphenylmethane 3.976228378
MESH:D003557 Phyllodes Tumor Doxorubicin 4.6617983394
MESH:D010900 Pituitary Diseases Iron 5.1716604332
MESH:D010954 Plasmacytoma Selenium 4.3915087411
MESH:D010997 Pleural Neoplasms Doxorubicin 4.6617638057
MESH:D011014 Pneumonia Paraquat 3.9712504350
MESH:D011041 Poisoning Iron 3.8516604332
MESH:D011085 Polycystic Ovary Syndrome Flutamide 4.5715356085
MESH:D017119 Porphyria Cutanea Tarda Iron 4.5216640825
MESH:D011230 Precancerous Conditions Diethylnitrosamine 3.142563599
MESH:D011225 Pre-Eclampsia Iron 8.2816640825
MESH:D011225 Pre-Eclampsia Zinc 8.2817114810
MESH:D011297 Prenatal Exposure Delayed Effects perfluorooctanoic acid 3.9117132714
MESH:D011471 Prostatic Neoplasms arsenic trioxide 2.0219131511
MESH:D011471 Prostatic Neoplasms Cadmium 2.0217075824
MESH:D011471 Prostatic Neoplasms Doxorubicin 2.0215897917 18437689 16868541 16729912 16888761 15749863
MESH:D011471 Prostatic Neoplasms Flutamide 2.023169114
MESH:D011471 Prostatic Neoplasms Lindane 2.0212661182 14688026
MESH:D011471 Prostatic Neoplasms Vitamin E 2.0215084515
MESH:D011471 Prostatic Neoplasms Zinc 2.0216606632 16517595 16700911 12429649
MESH:D011528 Protozoan Infections Iron 5.5216640825
MESH:D011645 Puerperal Infection Citric Acid 6.241108409
MESH:D011658 Pulmonary Fibrosis Amiodarone 5.1411597910 12832656 12490602
MESH:D011658 Pulmonary Fibrosis Paraquat 5.1417997886 16324872
MESH:D051437 Renal Insufficiency Doxorubicin 3.7517922066
MESH:D015427 Reperfusion Injury pirinixic acid 2.1319058328
MESH:D012128 Respiratory Distress Syndrome, Adult Oxygen 7.9617627322 18339021
MESH:D012128 Respiratory Distress Syndrome, Adult Paraquat 7.9611700416
MESH:D012135 Respiratory Sounds Paraquat 3.5811874814
MESH:D012148 Restless Legs Syndrome Iron 4.1816930377
MESH:D012162 Retinal Degeneration 4,4'-diaminodiphenylmethane 12.853692021
MESH:D012162 Retinal Degeneration Paraquat 12.8516458197
MESH:D012162 Retinal Degeneration Zinc 12.8516584753
MESH:D012174 Retinitis Pigmentosa manganese(III)-tetrakis(4-benzoic acid)porphyrin 4.4516849425
MESH:D012509 Sarcoma Doxorubicin 3.5717203757 16767912 18313854 15625365 15675481 17710206
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 8.7416646077
MESH:D012512 Sarcoma, Ewing's Doxorubicin 8.7414601052 16326096
MESH:D012514 Sarcoma, Kaposi Doxorubicin 4.3017846226
MESH:D012640 Seizures 2,6-dinitrotoluene 8.2218551238
MESH:D012640 Seizures Kainic Acid 8.2217827730 19414003 16336964 19186208 10686065 18657176 14637104 1641125 15686955
MESH:D012640 Seizures Lindane 8.227539098 15475178 12842176
OMIM:609620 SHORT QT SYNDROME 1 Amiodarone 4.6018724381
MESH:D012871 Skin Diseases Vitamin E 2.3018709164
MESH:D012878 Skin Neoplasms Doxorubicin 8.3615692506
MESH:D012878 Skin Neoplasms Glucose 8.3614993021
MESH:D012878 Skin Neoplasms Iron 8.3612065085
MESH:D012893 Sleep Disorders Kainic Acid 5.2119414003
MESH:D012983 Soft Tissue Neoplasms Doxorubicin 4.0915625365 17203757 16767912
MESH:D013272 Stomach Diseases Omeprazole 4.1318545984
MESH:D013274 Stomach Neoplasms arsenic trioxide 2.3017007042
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 2.3018456281
MESH:D013276 Stomach Ulcer Amiodarone 6.1618087811
MESH:D013276 Stomach Ulcer Omeprazole 6.1618237397 17977527 10750652 16755016 11906479 15991576
MESH:D020521 Stroke Vitamin E 3.1316517955
MESH:D013398 Sudden Infant Death Iron 11.6916640825
MESH:D013398 Sudden Infant Death Oxygen 11.6912563064
MESH:D013610 Tachycardia Amiodarone 9.6411238279
MESH:D013610 Tachycardia Nitroprusside 9.6415306635
MESH:D017180 Tachycardia, Ventricular Amiodarone 3.7319225199
MESH:D013959 Thyroid Diseases Amiodarone 4.2619731979
MESH:D013964 Thyroid Neoplasms 4,4'-diaminodiphenylmethane 18.531399818 7505956 6582329 3712494 6587162
MESH:D013964 Thyroid Neoplasms arsenic trioxide 18.5319014326
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 18.537505956
MESH:D013964 Thyroid Neoplasms Doxorubicin 18.5316010429 17909728
MESH:D013964 Thyroid Neoplasms Propylthiouracil 18.5315710170
MESH:D013971 Thyrotoxicosis Amiodarone 4.3818020914 19584973
MESH:D014062 Tongue Neoplasms Zinc 3.9816543248
MESH:D016171 Torsades de Pointes Amiodarone 8.6417467628 11989578
MESH:D016171 Torsades de Pointes arsenic trioxide 8.6415213294
MESH:D014376 Tuberculosis Iron 3.7716597321
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 10.1716049721
MESH:D001749 Urinary Bladder Neoplasms 4,4'-diaminodiphenylmethane 10.178074119
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 10.1712973940 20435036 12845720 11780464
MESH:D001749 Urinary Bladder Neoplasms Doxorubicin 10.1717653716
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 3.8310091137
MESH:D018487 Ventricular Dysfunction, Left Doxorubicin 3.7516364871 17638931 17678736 17334414
Pathway ID Pathway Name
KEGG:00020 Citrate cycle (TCA cycle)
KEGG:00630 Glyoxylate and dicarboxylate metabolism
KEGG:01100 Metabolic pathways
REACT:1046 Pyruvate metabolism and Citric Acid (TCA) cycle
Pharmacogenomics Knowledge Base Top
Drug Bank Top
Drugbank ID Action Drug Name Description
DB01727 - Isocitric Acid
DB03964 - 4-Hydroxy-Aconitate Ion
DB04072 - Alpha-Methylisocitric Acid
DB04351 - Aconitate Ion
DB04562 - Tricarballylic Acid
No data
No data
No data

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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