AutismKB 2.0

Annotation Detail for ORM2


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Basic Information Top
Gene Symbol:ORM2 ( AGP-B,AGP-B',AGP2 )
Gene Full Name: orosomucoid 2
Band: 9q32
Quick LinksEntrez ID:5005; OMIM: 138610; Uniprot ID:A1AG2_HUMAN; ENSEMBL ID: ENSG00000228278; HGNC ID: 8499
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C009505 4,4'-diaminodiphenylmethane 4,4'-diaminodiphenylmethane results in increased expression of ORM2 mRNAincreases expression 18648102
D000082 Acetaminophen Acetaminophen affects the expression of ORM2 mRNAaffects expression 17562736
15606129
D000082 Acetaminophen Acetaminophen results in decreased expression of ORM2 mRNAdecreases expression 11264010
C109238 acyline acyline results in decreased expression of ORM2 mRNAdecreases expression 17510436
C053342 brevetoxin brevetoxin analog results in decreased expression of ORM2 mRNAdecreases expression 14529743
C019304 ciprofibrate ciprofibrate results in decreased expression of ORM2 mRNAdecreases expression 12771043
D016572 Cyclosporine Cyclosporine results in decreased expression of ORM2 mRNAdecreases expression 20106945
D003907 Dexamethasone [Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of ORM2 mRNAaffects cotreatment|increases expression 16054899
D003907 Dexamethasone EGF protein inhibits the reaction [[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of ORM2 mRNA]affects cotreatment|decreases reaction|increases expression 16054899
D003907 Dexamethasone Tetrachlorodibenzodioxin inhibits the reaction [[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of ORM2 mRNA]affects cotreatment|decreases reaction|increases expression 16054899
D004052 Diethylnitrosamine Diethylnitrosamine results in increased expression of ORM2 mRNAincreases expression 12771043
D011345 Fenofibrate Fenofibrate results in decreased expression of ORM2 mRNAdecreases expression 11798191
D015056 1-Methyl-3-isobutylxanthine [Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of ORM2 mRNAaffects cotreatment|increases expression 16054899
D015056 1-Methyl-3-isobutylxanthine EGF protein inhibits the reaction [[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of ORM2 mRNA]affects cotreatment|decreases reaction|increases expression 16054899
D015056 1-Methyl-3-isobutylxanthine Tetrachlorodibenzodioxin inhibits the reaction [[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of ORM2 mRNA]affects cotreatment|decreases reaction|increases expression 16054899
D008070 Lipopolysaccharides Lipopolysaccharides results in increased expression of ORM2 mRNAincreases expression 17321000
C042763 olive oil olive oil analog affects the expression of ORM2 mRNAaffects expression 17349074
C023036 perfluorooctanoic acid perfluorooctanoic acid results in decreased expression of ORM2 mRNAdecreases expression 18467677
C023036 perfluorooctanoic acid PPARA protein promotes the reaction [perfluorooctanoic acid results in decreased expression of ORM2 mRNA]decreases expression|increases reaction 18467677
D010634 Phenobarbital NR1I3 protein affects the reaction [Phenobarbital results in increased expression of ORM2 mRNA]affects reaction|increases expression 19482888
D010634 Phenobarbital Phenobarbital results in increased expression of ORM2 mRNAincreases expression 19482888
19270015
C006253 pirinixic acid pirinixic acid results in decreased expression of ORM2 mRNAdecreases expression 11798191
18467677
20059764
17321000
C006253 pirinixic acid pirinixic acid results in increased expression of ORM2 mRNAincreases expression 18445702
C006253 pirinixic acid PPARA protein affects the reaction [pirinixic acid results in decreased expression of ORM2 mRNA]affects reaction|decreases expression 17321000
C006253 pirinixic acid PPARA protein promotes the reaction [pirinixic acid results in decreased expression of ORM2 mRNA]decreases expression|increases reaction 20059764
18467677
C089730 rosiglitazone [Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of ORM2 mRNAaffects cotreatment|increases expression 16054899
C089730 rosiglitazone EGF protein inhibits the reaction [[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of ORM2 mRNA]affects cotreatment|decreases reaction|increases expression 16054899
C089730 rosiglitazone Tetrachlorodibenzodioxin inhibits the reaction [[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of ORM2 mRNA]affects cotreatment|decreases reaction|increases expression 16054899
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin inhibits the reaction [[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of ORM2 mRNA]affects cotreatment|decreases reaction|increases expression 16054899
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Phenobarbital 8.276195326
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 8.2715322242 11752688 14514962
MESH:D055371 Acute Lung Injury Lipopolysaccharides 8.9811850527 18653653
MESH:D055371 Acute Lung Injury pirinixic acid 8.9818653653
MESH:D000236 Adenoma 4,4'-diaminodiphenylmethane 6.633712494
MESH:D000236 Adenoma Diethylnitrosamine 6.636695378 10737359
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 24.8216434500 19052882 18056438 17620307 17162532 19061943
MESH:D018248 Adenoma, Liver Cell Phenobarbital 24.8217620307
MESH:D018248 Adenoma, Liver Cell pirinixic acid 24.8216434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 24.8216835633
MESH:D000544 Alzheimer Disease rosiglitazone 2.8519621015
MESH:D000740 Anemia Tetrachlorodibenzodioxin 2.9311748828
MESH:D000799 Angioedema Acetaminophen 3.8410982225
MESH:D001169 Arthritis, Experimental Dexamethasone 3.5217659584
MESH:D050197 Atherosclerosis olive oil 4.3216216721
MESH:D001321 Autistic Disorder Acetaminophen 1.4218445737
MESH:D001660 Biliary Tract Diseases 4,4'-diaminodiphenylmethane 5.021440618 11289319
MESH:D001778 Blood Coagulation Disorders pirinixic acid 8.7119483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 8.7112125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.7915340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.7515746008
MESH:D001943 Breast Neoplasms Diethylnitrosamine 1.9717474063
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 1.9720435547
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.7816835633
MESH:D006528 Carcinoma, Hepatocellular 4,4'-diaminodiphenylmethane 6.533581430 7296757
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 6.533084413
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 6.5319335982 20727157 16698587 16569478 19171122 17055752 18971187 17162532 21159647 19383236 20512989 16502159 19394651 16328049 16288022 3084413 16830150 18665156 19519916 19208518 3581430 10672840 20524982 17761372 18978308 16681979 17173139 16878318 19822196 19701751 18506893 20432363 20007298 19919837 17428255 18210153 17138121 18788625 16807293 19107877 11831363 18056438 19418558 19052882 17978847 20214788 20935162 10737359 16540662 16935385 20084675 20101231 18785209 18393292 16779866 18494052 20514400 18691550 19539802
MESH:D006528 Carcinoma, Hepatocellular Phenobarbital 6.5320007298 20935162 17173139 6705139 1701930
MESH:D002292 Carcinoma, Renal Cell 4,4'-diaminodiphenylmethane 2.667296757
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.3518850075 18670907 16120746
MESH:D002318 Cardiovascular Diseases olive oil 4.5216216721
MESH:D002386 Cataract Acetaminophen 2.5710977129
MESH:D002471 Cell Transformation, Neoplastic 4,4'-diaminodiphenylmethane 11.077505956
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 11.0712371664
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 11.0717174075 7505956 21159647 2727394
MESH:D002493 Central Nervous System Diseases Phenobarbital 4.244080065
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 9.2619052882
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 9.2616835633
MESH:D002779 Cholestasis 4,4'-diaminodiphenylmethane 13.299022650 19486331
MESH:D002779 Cholestasis Cyclosporine 13.2919486331
MESH:D002779 Cholestasis pirinixic acid 13.2919176532
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 2.0916354765 15668235 15340226 8697196 12621046
MESH:D003110 Colonic Neoplasms Dexamethasone 2.4915824018
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 3.0417141729 14669216
MESH:D019465 Craniofacial Abnormalities Dexamethasone 2.6117728286
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 2.6110048152 20055451 15322242
MESH:D017449 Dermatitis, Allergic Contact 4,4'-diaminodiphenylmethane 7.0012868966 11298694 2524372 8970840 18759878 11906362 8156756 14531868
MESH:D017449 Dermatitis, Allergic Contact Dexamethasone 7.0012438553
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.4118249437
MESH:D003877 Dermatitis, Contact 4,4'-diaminodiphenylmethane 3.473621924 2952479
MESH:D003920 Diabetes Mellitus rosiglitazone 4.2817446233
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 7.1420387270
MESH:D003924 Diabetes Mellitus, Type 2 rosiglitazone 7.1412642470
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 7.1417107852
MESH:D003967 Diarrhea Dexamethasone 3.687237001
MESH:D056486 Drug-Induced Liver Injury 4,4'-diaminodiphenylmethane 8.8918648102 1440618 9653073 18289764 18692083 16192314 6482804 9022650 11289319 8291058 7440962 6679447 9328219
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 8.8916781746 11287661 19370779 15968718 11743745 15619225 12705907 16109766 19164858 16227642 14725611 11834606 17562736 17522070 10663392 19085960 2444490 14986274 11461765 17906064 18071297 19420014 18713872 11421492 19923254 19416960 12392966 10915739 16393943 10774834 12540782 16177239 11739529 19739265 11529661 16081117 12153990 12958197 12594235 14550746 16485898
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 8.8919107877
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 8.8920420201
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.1019426721
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.7411462148
MESH:D050171 Dyslipidemias Fenofibrate 4.4116707586
MESH:D004421 Dystonia Phenobarbital 3.991851702
MESH:D004485 Eczema Dexamethasone 4.4412438553
MESH:D004487 Edema Dexamethasone 21.4919703484
MESH:D004487 Edema perfluorooctanoic acid 21.4912083418 17259670
MESH:D004487 Edema pirinixic acid 21.4912083418
MESH:D004487 Edema rosiglitazone 21.4912083418
MESH:D004487 Edema Tetrachlorodibenzodioxin 21.4911000095 12711302
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 3.9015322242 16714409 18230668
MESH:D016889 Endometrial Neoplasms Fenofibrate 4.0816569247
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 3.0010568697 9294722
MESH:D019446 Endotoxemia Lipopolysaccharides 4.3917637181 15328337 15821434
MESH:D004831 Epilepsies, Myoclonic Phenobarbital 4.093659116
MESH:D004828 Epilepsies, Partial Phenobarbital 3.873922381 11558140
MESH:D004827 Epilepsy Phenobarbital 2.8820417680
MESH:D004832 Epilepsy, Absence Phenobarbital 3.526401628
MESH:D017029 Epilepsy, Complex Partial Phenobarbital 4.247750514
MESH:D004830 Epilepsy, Tonic-Clonic Phenobarbital 4.013659116
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 5.1216302075
MESH:D004938 Esophageal Neoplasms 4,4'-diaminodiphenylmethane 2.103581430
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 3.0011564622
MESH:D005234 Fatty Liver Cyclosporine 18.6519224547
MESH:D005234 Fatty Liver Diethylnitrosamine 18.6521071580 20387270
MESH:D005234 Fatty Liver pirinixic acid 18.6519236843 20131406
MESH:D005234 Fatty Liver rosiglitazone 18.6519196556
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.4411858732
MESH:D005334 Fever Lipopolysaccharides 3.999205823 11852909
MESH:D005350 Fibroma 4,4'-diaminodiphenylmethane 5.026705139
MESH:D005355 Fibrosis Cyclosporine 8.4412639820 12168785
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 8.4420067830
MESH:D005756 Gastritis Acetaminophen 3.6816983495
MESH:D005885 Gingival Hyperplasia Cyclosporine 4.218708960
MESH:D006042 Goiter 4,4'-diaminodiphenylmethane 4.027505956
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.5910696789
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 2.3211294989 10048152
MESH:D006333 Heart Failure pirinixic acid 2.5220558911
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.4115720958
MESH:D006463 Hemolytic-Uremic Syndrome Lipopolysaccharides 4.3616366002
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.3211000095
MESH:D006505 Hepatitis 4,4'-diaminodiphenylmethane 3.506705139
MESH:D006529 Hepatomegaly perfluorooctanoic acid 20.603609246
MESH:D006529 Hepatomegaly Phenobarbital 20.6016109766
MESH:D006529 Hepatomegaly pirinixic acid 20.6019176532 18467677 19772884 16221962
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 20.6016120746 15340226 12621046
MESH:D006548 Hernia, Diaphragmatic Dexamethasone 3.067520565
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 4.0516959395 15340226 16354765 8697196 18606429
MESH:D006930 Hyperalgesia Acetaminophen 13.0816870215
MESH:D006930 Hyperalgesia perfluorooctanoic acid 13.0812083418
MESH:D006930 Hyperalgesia rosiglitazone 13.0812083418
MESH:D006943 Hyperglycemia pirinixic acid 3.1620558911
MESH:D006965 Hyperplasia 4,4'-diaminodiphenylmethane 3.9215034207
MESH:D006973 Hypertension Cyclosporine 8.5410903974
MESH:D006973 Hypertension Dexamethasone 8.5417042910
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 8.5418670907 18850075
MESH:D007077 Ileal Diseases 1-Methyl-3-isobutylxanthine 5.4418306037
MESH:D007249 Inflammation Dexamethasone 19.868960868 11099482
MESH:D007249 Inflammation Diethylnitrosamine 19.8618785209
MESH:D007249 Inflammation Lipopolysaccharides 19.8617237260 9205823 12878042 17255318 17963957
MESH:D007249 Inflammation perfluorooctanoic acid 19.8612083418
MESH:D007249 Inflammation rosiglitazone 19.8612083418
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 19.8612200463 12878042
MESH:D007333 Insulin Resistance pirinixic acid 7.4616306350
MESH:D007333 Insulin Resistance rosiglitazone 7.4616306350
MESH:D019189 Iron Metabolism Disorders Lipopolysaccharides 4.6117255318
MESH:D007565 Jaundice 4,4'-diaminodiphenylmethane 5.029022650 8074119
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 3.3216580747
MESH:D007579 Jejunal Diseases 1-Methyl-3-isobutylxanthine 5.4418306037
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.4415604871
MESH:D007674 Kidney Diseases Acetaminophen 5.7512587719 15629191
MESH:D007674 Kidney Diseases Cyclosporine 5.7518776723 10903974 8314463
MESH:D007680 Kidney Neoplasms 4,4'-diaminodiphenylmethane 7.216582329
MESH:D007680 Kidney Neoplasms Cyclosporine 7.2112371664
MESH:D007970 Leukopenia Lipopolysaccharides 4.6915821434
MESH:D007984 Leydig Cell Tumor perfluorooctanoic acid 5.228812269
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 6.6019638242 20032147 18665156 18522880 18407596
MESH:D008103 Liver Cirrhosis Phenobarbital 6.6021047994
MESH:D008105 Liver Cirrhosis, Biliary 4,4'-diaminodiphenylmethane 3.189327722 15034207
MESH:D008106 Liver Cirrhosis, Experimental Dexamethasone 8.7316718785
MESH:D008106 Liver Cirrhosis, Experimental Fenofibrate 8.7315474484
MESH:D008106 Liver Cirrhosis, Experimental Lipopolysaccharides 8.7312878042
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 8.7315474484
MESH:D008106 Liver Cirrhosis, Experimental rosiglitazone 8.7317347453 15980055
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 8.7312878042
MESH:D008107 Liver Diseases Acetaminophen 6.4512587719 19784758 19460945 12969438 16610002 19014921 16611625 11587558
MESH:D008107 Liver Diseases Diethylnitrosamine 6.4517034775
MESH:D008107 Liver Diseases Phenobarbital 6.4519363144
MESH:D017114 Liver Failure, Acute Acetaminophen 3.2216871587 17185352
MESH:D008113 Liver Neoplasms ciprofibrate 21.8112771043
MESH:D008113 Liver Neoplasms Diethylnitrosamine 21.8115885732 20405173 18648771 19996281 19426721 19499222 20434301 19833225 20101389 10737359 20118626 12112319 19254457 21278145 18978307 19256749 15175105 19427195 19812893 21167192 18644402 12771043 19850985 21071580 19551842 19073162 20501860 2422723 19690152 19255062 18754104 19638242 19294768 20583210 18977376 19090486 20452335 20137499 21047994 16942905 9163691 2862719 20492335 19642983
MESH:D008113 Liver Neoplasms Fenofibrate 21.8118978307
MESH:D008113 Liver Neoplasms perfluorooctanoic acid 21.8118709148 14757943
MESH:D008113 Liver Neoplasms Phenobarbital 21.8119482888 8742319 15975961 19073162 21047994 19812893
MESH:D008113 Liver Neoplasms pirinixic acid 21.8120007298 16377806 15890375
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 21.8116984957
MESH:D008114 Liver Neoplasms, Experimental 4,4'-diaminodiphenylmethane 18.536587162 1399818 3712494 598648
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 18.5316842330 17854601 18079962 19539802 19126423 17174075 18775883 18544905 17942915 19004024 19519916 21159647 18282651 19009564 3124819 16267830 2563599 18308698 9362446 18253720 18164116 18093689
MESH:D008114 Liver Neoplasms, Experimental Fenofibrate 18.5318775883 18253720
MESH:D008114 Liver Neoplasms, Experimental Phenobarbital 18.5318308698 6150874 2563599 17172636 1399818
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 18.5312151625
MESH:D055370 Lung Injury Lipopolysaccharides 3.9921114838
MESH:D008175 Lung Neoplasms Dexamethasone 3.4315824018 11195469
MESH:D008175 Lung Neoplasms Diethylnitrosamine 3.436695378 20970405 20512841 21163286
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 3.4311884234 19555203
MESH:D008325 Mammary Neoplasms, Experimental rosiglitazone 3.3816827153
MESH:D008546 Melanoma, Experimental Acetaminophen 3.5519513568
MESH:D024821 Metabolic Syndrome X rosiglitazone 4.3617261469
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.7916801185
MESH:D009101 Multiple Myeloma Dexamethasone 3.4915867202 16118317 15744524
MESH:D009135 Muscular Diseases pirinixic acid 3.4916239165
MESH:D009190 Myelodysplastic Syndromes Dexamethasone 3.539809623
MESH:D009203 Myocardial Infarction pirinixic acid 2.1319151258
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 3.0012213967
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 2.9316411023
MESH:D020191 Myoclonic Epilepsies, Progressive Phenobarbital 4.4717484760
MESH:D009362 Neoplasm Metastasis 4,4'-diaminodiphenylmethane 5.673581430
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 5.673581430 9029167
MESH:D009369 Neoplasms pirinixic acid 1.9417405874
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.4417954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.2719348381 18481113
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 3.2014600291
MESH:D009436 Neural Tube Defects 4,4'-diaminodiphenylmethane 2.906679447
MESH:D019636 Neurodegenerative Diseases Acetaminophen 8.1218514411
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 8.1220387270
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 5.1220387270
MESH:D052556 Niemann-Pick Disease, Type C perfluorooctanoic acid 4.949802331
MESH:D009765 Obesity pirinixic acid 1.8120558911
MESH:D009784 Occupational Diseases 4,4'-diaminodiphenylmethane 3.406482804 4026338
MESH:D009902 Optic Neuritis 4,4'-diaminodiphenylmethane 5.023988306
MESH:D010018 Osteomalacia Phenobarbital 4.3617016548
MESH:D010146 Pain Acetaminophen 2.3716870215
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 5.2416540662
MESH:D010190 Pancreatic Neoplasms Phenobarbital 5.2416965848
MESH:D010212 Papilloma 4,4'-diaminodiphenylmethane 3.477296757
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.2512520081
MESH:D010787 Photosensitivity Disorders 4,4'-diaminodiphenylmethane 4.476228378
MESH:D011014 Pneumonia Lipopolysaccharides 4.5512224865 11605937
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.5418163543
MESH:D011230 Precancerous Conditions Cyclosporine 15.1712371664
MESH:D011230 Precancerous Conditions Diethylnitrosamine 15.172563599
MESH:D011230 Precancerous Conditions Phenobarbital 15.172563599
MESH:D054198 Precursor Cell Lymphoblastic Leukemia-Lymphoma Dexamethasone 3.5321297632
MESH:D011297 Prenatal Exposure Delayed Effects perfluorooctanoic acid 9.6417132714
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 9.6411118676 11399792 11896295 11222880
MESH:D019310 Pseudolymphoma Phenobarbital 4.5012752131
MESH:D011565 Psoriasis Cyclosporine 2.2216882103
MESH:D015427 Reperfusion Injury pirinixic acid 2.3819058328
MESH:D012128 Respiratory Distress Syndrome, Adult Dexamethasone 4.0018379247 11700416
MESH:D012130 Respiratory Hypersensitivity Lipopolysaccharides 3.7210835634
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.8218990726
MESH:D012162 Retinal Degeneration 4,4'-diaminodiphenylmethane 3.363692021
MESH:D012640 Seizures Phenobarbital 2.6816876388 3137016 4039156 11442880
MESH:D003294 Seizures, Febrile Phenobarbital 4.816407741
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 2.0316192470
MESH:D013272 Stomach Diseases Dexamethasone 4.3115472012
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 1.7518456281
MESH:D013276 Stomach Ulcer Dexamethasone 7.8515138204
MESH:D013276 Stomach Ulcer olive oil 7.8516252198 12498302
MESH:D013921 Thrombocytopenia Lipopolysaccharides 4.1515821434
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.9012697716
MESH:D013964 Thyroid Neoplasms 4,4'-diaminodiphenylmethane 11.867505956 1399818 6587162 3712494 6582329
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 11.867505956
MESH:D013964 Thyroid Neoplasms Phenobarbital 11.861399818
MESH:D001749 Urinary Bladder Neoplasms 4,4'-diaminodiphenylmethane 2.278074119
MESH:D014581 Urticaria Acetaminophen 2.9610982225
MESH:D014605 Uveitis Cyclosporine 11.771336536
MESH:D014605 Uveitis Dexamethasone 11.771336536
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.5912125929
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.2515886252
MESH:D014985 Xerophthalmia Cyclosporine 4.4417120751
No data
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA32818
    • No data
    Releated disease ID Related disease Name
    PA447230HIV
    Releated drug ID Related drug Name
    PA451906warfarin
    PA449441efavirenz
    PA449977indinavir
    PA450264lopinavir
    PA450606nelfinavir
    PA451260ritonavir
    PA452621antineoplastic agents
    Drug Bank Top

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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