Annotation Detail for OTX1
Basic Information
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| Chemical ID |
Chemical Name |
Interaction |
Interaction Action |
Publication |
|---|
| D000082 |
Acetaminophen |
Acetaminophen results in increased expression of OTX1 protein | increases expression | 15800402
|
| D001104 |
Arbutin |
Arbutin results in decreased expression of OTX1 mRNA | decreases expression | 17103032
|
| D000431 |
Ethanol |
Ethanol results in decreased expression of OTX1 mRNA | decreases expression | 17920746
|
| C011890 |
kojic acid |
kojic acid results in increased expression of OTX1 mRNA | increases expression | 16595896
|
| Disease ID |
Disease Name |
Direct Evidence |
Inference Chemical Name |
Inference Score |
Publication |
|---|
| MESH:D000014 |
Abnormalities, Drug-Induced |
|
Ethanol |
4.55 | 17676605 18926900 |
| MESH:D000138 |
Acidosis |
|
Ethanol |
5.13 | 11192467 |
| MESH:D020268 |
Alcohol-Induced Disorders, Nervous System |
|
Ethanol |
6.04 | 15451040 15451039 |
| MESH:D000799 |
Angioedema |
|
Acetaminophen |
4.57 | 10982225 |
| MESH:D000853 |
Anophthalmos |
|
Ethanol |
5.38 | 15513904 |
| MESH:D001008 |
Anxiety Disorders |
|
Ethanol |
4.33 | 11141031 |
| MESH:D001321 |
Autistic Disorder |
|
Acetaminophen |
1.40 | 18445737 |
| MESH:D002056 |
Burns |
|
Ethanol |
5.21 | 16374292 |
| MESH:D006528 |
Carcinoma, Hepatocellular |
|
Acetaminophen |
3.19 | 3084413 |
| MESH:D006528 |
Carcinoma, Hepatocellular |
|
Ethanol |
3.19 | 15763234 15289165 18788625 |
| MESH:D006332 |
Cardiomegaly |
|
Ethanol |
3.63 | 19332462 |
| MESH:D002386 |
Cataract |
|
Acetaminophen |
2.79 | 10977129 |
| MESH:D002971 |
Cleft Lip |
|
Ethanol |
3.76 | 15513904 |
| MESH:D002972 |
Cleft Palate |
|
Ethanol |
3.31 | 15513904 |
| MESH:D019465 |
Craniofacial Abnormalities |
|
Ethanol |
2.34 | 15451039 15451040 19302082 15513904 11198716 11873399 10194807 |
| MESH:D056486 |
Drug-Induced Liver Injury |
|
Acetaminophen |
4.26 | 15619225 12958197 11529661 17522070 16177239 11834606 12594235 16781746 19164858 19416960 14550746 11461765 18713872 11421492 17562736 12705907 10774834 16081117 11743745 10915739 15968718 19739265 16393943 14725611 12540782 18071297 19370779 16227642 19420014 10663392 16485898 11287661 19923254 12153990 2444490 17906064 12392966 14986274 19085960 16109766 11739529 |
| MESH:D056486 |
Drug-Induced Liver Injury |
|
Ethanol |
4.26 | 11566570 |
| MESH:D056487 |
Drug-Induced Liver Injury, Chronic |
|
Acetaminophen |
4.82 | 19426721 |
| MESH:D004938 |
Esophageal Neoplasms |
|
Ethanol |
2.83 | 16704527 |
| MESH:D005234 |
Fatty Liver |
|
Ethanol |
4.16 | 19236843 16409862 18620774 |
| MESH:D005235 |
Fatty Liver, Alcoholic |
|
Ethanol |
6.39 | 17920746 |
| MESH:D005310 |
Fetal Alcohol Syndrome |
|
Ethanol |
5.93 | 16946407 15513904 15451040 10194807 |
| MESH:D005756 |
Gastritis |
|
Acetaminophen |
13.67 | 16983495 |
| MESH:D005756 |
Gastritis |
|
Ethanol |
13.67 | 15046732 |
| MESH:D006930 |
Hyperalgesia |
|
Acetaminophen |
8.91 | 16870215 |
| MESH:D006930 |
Hyperalgesia |
|
Ethanol |
8.91 | 18783367 |
| MESH:D007569 |
Jaw Abnormalities |
|
Ethanol |
4.83 | 15513904 |
| MESH:D007674 |
Kidney Diseases |
|
Acetaminophen |
2.40 | 15629191 12587719 |
| MESH:D007859 |
Learning Disorders |
|
Ethanol |
4.77 | 15451040 |
| MESH:D017880 |
Limb Deformities, Congenital |
|
Ethanol |
4.09 | 17676605 |
| MESH:D008103 |
Liver Cirrhosis |
|
Ethanol |
3.56 | 15289165 |
| MESH:D008104 |
Liver Cirrhosis, Alcoholic |
|
Ethanol |
5.73 | 18295389 |
| MESH:D008106 |
Liver Cirrhosis, Experimental |
|
Ethanol |
2.32 | 18166357 |
| MESH:D008107 |
Liver Diseases |
|
Acetaminophen |
1.70 | 19014921 16610002 12587719 16611625 12969438 11587558 19460945 19784758 |
| MESH:D008108 |
Liver Diseases, Alcoholic |
|
Ethanol |
5.21 | 17207112 17347304 |
| MESH:D017114 |
Liver Failure, Acute |
|
Acetaminophen |
3.63 | 16871587 17185352 |
| MESH:D008114 |
Liver Neoplasms, Experimental |
|
kojic acid |
3.55 | 18544905 |
| MESH:D008546 |
Melanoma, Experimental |
|
Acetaminophen |
4.13 | 19513568 |
| MESH:D008569 |
Memory Disorders |
|
Ethanol |
4.69 | 18411066 15451040 |
| MESH:D019636 |
Neurodegenerative Diseases |
|
Acetaminophen |
3.21 | 18514411 |
| MESH:D010146 |
Pain |
|
Acetaminophen |
2.73 | 16870215 |
| MESH:D010190 |
Pancreatic Neoplasms |
|
Ethanol |
3.08 | 12384795 |
| MESH:D012640 |
Seizures |
|
Ethanol |
3.42 | 9754883 |
| MESH:D013274 |
Stomach Neoplasms |
|
Ethanol |
2.31 | 18456281 |
| MESH:D013276 |
Stomach Ulcer |
|
Ethanol |
3.95 | 9211565 11906479 17189318 16755016 9562338 17918041 |
| MESH:D013375 |
Substance Withdrawal Syndrome |
|
Ethanol |
4.65 | 9754883 |
| MESH:D014581 |
Urticaria |
|
Acetaminophen |
3.44 | 10982225 |
Related Pathway Information