AutismKB 2.0

Annotation Detail for OVGP1


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Basic Information Top
Gene Symbol:OVGP1 ( CHIT5,EGP,MUC9,OGP )
Gene Full Name: oviductal glycoprotein 1, 120kDa
Band: 1p13.2
Quick LinksEntrez ID:5016; OMIM: 603578; Uniprot ID:OVGP1_HUMAN; ENSEMBL ID: ENSG00000085465; HGNC ID: 8524
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1881Uterine disease
Desease Name
CHEMDEPENDENCY
smoking cessation
No data
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000082 Acetaminophen Acetaminophen affects the expression of OVGP1 mRNAaffects expression 17562736
D004958 Estradiol Estradiol results in increased expression of OVGP1 proteinincreases expression 15501902
D004958 Estradiol Progesterone inhibits the reaction [Estradiol results in increased expression of OVGP1 protein]decreases reaction|increases expression 15501902
C006253 pirinixic acid [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of OVGP1 mRNAaffects binding|decreases expression|increases activity 19710929
D011374 Progesterone Progesterone inhibits the reaction [Estradiol results in increased expression of OVGP1 protein]decreases reaction|increases expression 15501902
D011374 Progesterone Progesterone affects the expression of OVGP1 mRNAaffects expression 17251523
D012643 Selenium [Selenium co-treated with Vitamin E] results in decreased expression of OVGP1 mRNAaffects cotreatment|decreases expression 19244175
D012643 Selenium Selenium results in increased expression of OVGP1 mRNAincreases expression 19244175
D014810 Vitamin E [Selenium co-treated with Vitamin E] results in decreased expression of OVGP1 mRNAaffects cotreatment|decreases expression 19244175
D014810 Vitamin E Vitamin E results in decreased expression of OVGP1 mRNAdecreases expression 19244175
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D055371 Acute Lung Injury pirinixic acid 3.4718653653
MESH:D000230 Adenocarcinoma Estradiol 2.1611473722
MESH:D018248 Adenoma, Liver Cell pirinixic acid 3.9416434500
MESH:D000799 Angioedema Acetaminophen 4.3610982225
MESH:D001321 Autistic Disorder Acetaminophen 1.4018445737
MESH:D001778 Blood Coagulation Disorders pirinixic acid 3.4719483382
MESH:D020201 Brain Hemorrhage, Traumatic Progesterone 5.8617868700
MESH:D001930 Brain Injuries Progesterone 4.6815665606 15845082 15380490
MESH:D001943 Breast Neoplasms Estradiol 2.1818497071 14630087 17289903 19861407 12948864 17261762 17018787 16675129
MESH:D001943 Breast Neoplasms Progesterone 2.1816175315 15562024 17614352
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 4.9316111702
MESH:D002252 Carbon Tetrachloride Poisoning Vitamin E 4.3516050911
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 2.943084413
MESH:D006528 Carcinoma, Hepatocellular Estradiol 2.9416924424
MESH:D002386 Cataract Acetaminophen 2.7510977129
MESH:D002471 Cell Transformation, Neoplastic Estradiol 2.9818566989
MESH:D002779 Cholestasis pirinixic acid 3.0519176532
MESH:D003092 Colitis Selenium 4.2017936198
MESH:D019465 Craniofacial Abnormalities Vitamin E 1.9219769572
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.5518249437
MESH:D003928 Diabetic Nephropathies Estradiol 3.7019279558
MESH:D003929 Diabetic Neuropathies Progesterone 4.9117187935
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 4.0412958197 11739529 14725611 11461765 16227642 14550746 11834606 10663392 16393943 12153990 12705907 11743745 11421492 2444490 17522070 15619225 15968718 12594235 10774834 19164858 11287661 19416960 10915739 19923254 16485898 18713872 16081117 19739265 14986274 12540782 18071297 11529661 17906064 19420014 16109766 16177239 12392966 19370779 17562736 16781746 19085960
MESH:D056486 Drug-Induced Liver Injury Selenium 4.0415131321
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.6219426721
MESH:C538011 Eales disease Vitamin E 5.229068938
MESH:D004487 Edema pirinixic acid 2.8012083418
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Progesterone 4.1617692515
MESH:D016889 Endometrial Neoplasms Estradiol 3.1711473722 18566989 19148513
MESH:D004715 Endometriosis Progesterone 4.0716134523
MESH:D005234 Fatty Liver pirinixic acid 3.0920131406 19236843
MESH:D005756 Gastritis Acetaminophen 4.1916983495
MESH:D006330 Heart Defects, Congenital Vitamin E 3.1316080930
MESH:D006333 Heart Failure pirinixic acid 7.5520558911
MESH:D006333 Heart Failure Selenium 7.5517162251
MESH:D006529 Hepatomegaly pirinixic acid 3.4116221962 18467677 19772884 19176532
MESH:D006548 Hernia, Diaphragmatic Vitamin E 2.7916863852 16490937
MESH:D006558 Herpes Genitalis Estradiol 5.5515709030
MESH:D019584 Hot Flashes Estradiol 11.8517088409
MESH:D019584 Hot Flashes Vitamin E 11.8514716179
MESH:D006930 Hyperalgesia Acetaminophen 2.9516870215
MESH:D006943 Hyperglycemia pirinixic acid 3.4920558911
MESH:D020244 Infarction, Middle Cerebral Artery Progesterone 4.8215869954
MESH:D007249 Inflammation Progesterone 2.7415869954
MESH:D007251 Influenza, Human Selenium 12.7616624496
MESH:D007251 Influenza, Human Vitamin E 12.7616624496
MESH:D007333 Insulin Resistance Estradiol 7.8416627594 16393666
MESH:D007333 Insulin Resistance pirinixic acid 7.8416306350
MESH:D007674 Kidney Diseases Acetaminophen 11.0112587719 15629191
MESH:D007674 Kidney Diseases Estradiol 11.0115618244
MESH:D007674 Kidney Diseases Vitamin E 11.0112488133
MESH:D007676 Kidney Failure, Chronic Selenium 4.2116518626
MESH:D007680 Kidney Neoplasms Estradiol 3.2415610895
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 3.6314659978 14716833
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 3.6315474484
MESH:D008106 Liver Cirrhosis, Experimental Vitamin E 3.6316169303
MESH:D008107 Liver Diseases Acetaminophen 1.6919460945 16610002 12969438 16611625 19784758 11587558 12587719 19014921
MESH:D017114 Liver Failure, Acute Acetaminophen 3.5416871587 17185352
MESH:D008113 Liver Neoplasms pirinixic acid 1.9116377806 15890375 20007298
MESH:D008171 Lung Diseases Vitamin E 3.3716863852
MESH:D008175 Lung Neoplasms Vitamin E 1.9011062179
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 11.1217203775 11408345 16891317 11807958
MESH:D008325 Mammary Neoplasms, Experimental Progesterone 11.1211408345 17203775
MESH:D008325 Mammary Neoplasms, Experimental Selenium 11.1215318939
MESH:D020149 Manganese Poisoning Estradiol 5.0019453300
MESH:D008546 Melanoma, Experimental Acetaminophen 3.9819513568
MESH:D008654 Mesothelioma Selenium 2.8915107826
MESH:D009135 Muscular Diseases pirinixic acid 3.9216239165
MESH:D009203 Myocardial Infarction pirinixic acid 2.2519151258
MESH:D015428 Myocardial Reperfusion Injury Estradiol 9.0616810080
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 9.0616411023
MESH:D009369 Neoplasms pirinixic acid 2.0817405874
MESH:D009389 Neovascularization, Pathologic Estradiol 4.1917289903
MESH:D009421 Nervous System Malformations Estradiol 4.0316427766 11399458
MESH:D019636 Neurodegenerative Diseases Acetaminophen 3.1418514411
MESH:D009765 Obesity pirinixic acid 1.8720558911
MESH:D010051 Ovarian Neoplasms Estradiol 5.1419401270
MESH:D010051 Ovarian Neoplasms Progesterone 5.1417393432 16525653
MESH:D010146 Pain Acetaminophen 2.6516870215
MESH:D010954 Plasmacytoma Selenium 5.4115087411
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 4.2120887781
MESH:D011471 Prostatic Neoplasms Estradiol 3.1616740699
MESH:D011471 Prostatic Neoplasms Vitamin E 3.1615084515
MESH:D015427 Reperfusion Injury pirinixic acid 2.5219058328
MESH:D012468 Salivary Gland Neoplasms Progesterone 2.9418045962
MESH:D012871 Skin Diseases Vitamin E 2.5018709164
MESH:D013119 Spinal Cord Injuries Progesterone 4.7415862959 16503802
MESH:D020521 Stroke Vitamin E 3.7716517955
MESH:D013978 Tibial Fractures Estradiol 5.2119048282
MESH:D014581 Urticaria Acetaminophen 3.3310982225
No data
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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