AutismKB 2.0

Annotation Detail for PAFAH1B1


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Basic Information Top
Gene Symbol:PAFAH1B1 ( LIS1,LIS2,MDCR,MDS,PAFAH )
Gene Full Name: platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
Band: 17p13.3
Quick LinksEntrez ID:5048; OMIM: 601545; Uniprot ID:LIS1_HUMAN; ENSEMBL ID: ENSG00000007168; HGNC ID: 8574
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa00565Ether lipid metabolism
hsa01100Metabolic pathways
Pathway IDPathway Name
Cell Cycle, Mitotic
DNA Replication
Pathway IDPathway Name
200114Lissencephaly gene (LIS1) in neuronal migration and development
200051Reelin signaling pathway
No data
Pathway IDPathway Name
500383Loss of proteins required for interphase microtubule organization from the centrosome
500380Centrosome maturation
500381Recruitment of mitotic centrosome proteins and complexes
500384Loss of Nlp from mitotic centrosomes
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1803Periodontitis
1832Congenital abnormality
2074Asthma
2259Hereditary disease
Desease Name
CARDIOVASCULAR
graft occlusion, atherosclerotic
Asthma. atopy. spIgE.
Asthma
Total IgE. atopic asthma
IMMUNE
Asthma. atopy
atherosclerosis, coronary myocardial infarct
No data
Desease Name
Subcortical laminar heterotopia
Lissencephaly-1
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C016403 2,4-dinitrotoluene 2,4-dinitrotoluene affects the expression of PAFAH1B1 mRNAaffects expression 21346803
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene affects the expression of PAFAH1B1 mRNAaffects expression 21346803
D000643 Ammonium Chloride Ammonium Chloride affects the expression of PAFAH1B1 mRNAaffects expression 16483693
D001564 Benzo(a)pyrene Benzo(a)pyrene results in decreased expression of PAFAH1B1 mRNAdecreases expression 20064835
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of PAFAH1B1 mRNAdecreases expression 19150397
D020122 tert-Butylhydroperoxide tert-Butylhydroperoxide results in decreased expression of PAFAH1B1 mRNAdecreases expression 15336504
D002118 Calcium Calcium promotes the reaction [PAFAH1B1 protein binds to IQGAP1 protein binds to CDC42 protein]affects binding|increases reaction 16369480
D004958 Estradiol Estradiol results in increased expression of PAFAH1B1 mRNAincreases expression 20068009
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of PAFAH1B1 mRNAincreases expression 17942748
D004997 Ethinyl Estradiol [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of PAFAH1B1 mRNAaffects cotreatment|increases expression 17942748
D005419 Flavonoids Flavonoids results in increased expression of PAFAH1B1 mRNAincreases expression 18035473
D005472 Fluorouracil TP53 protein affects the reaction [Fluorouracil results in decreased expression of PAFAH1B1 mRNA]affects reaction|decreases expression 15016801
D007657 Ketone Bodies Ketone Bodies results in increased expression of PAFAH1B1 mRNAincreases expression 16807920
C014707 nitrosobenzylmethylamine nitrosobenzylmethylamine results in increased expression of PAFAH1B1 mRNAincreases expression 17616710
D010672 Phenytoin Phenytoin results in decreased expression of PAFAH1B1 mRNAdecreases expression 15136057
D011794 Quercetin Quercetin results in increased expression of PAFAH1B1 proteinincreases expression 15221776
D012643 Selenium [Selenium co-treated with Vitamin E] results in increased expression of PAFAH1B1 mRNAaffects cotreatment|increases expression 19244175
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of PAFAH1B1 mRNAaffects cotreatment|increases expression 17942748
C025643 vinclozolin vinclozolin affects the expression of PAFAH1B1 mRNAaffects expression 19015723
D014810 Vitamin E [Selenium co-treated with Vitamin E] results in increased expression of PAFAH1B1 mRNAaffects cotreatment|increases expression 19244175
D014810 Vitamin E Vitamin E results in decreased expression of PAFAH1B1 mRNAdecreases expression 19244175
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Phenytoin 8.4810563481 3425630 9677735 8986270 6195326 9118846
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 8.4811752688 15322242 14514962
MESH:D000138 Acidosis Ammonium Chloride 3.5018287403
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.8917505938
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 10.0220127859 20464547
MESH:D000230 Adenocarcinoma Estradiol 10.0211473722
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 10.0214692618
MESH:D000230 Adenocarcinoma Fluorouracil 10.0217638652
MESH:D000236 Adenoma Benzo(a)pyrene 2.616695378
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 3.3216835633
MESH:D000740 Anemia Fluorouracil 8.4815504547 17963324 16511603
MESH:D000740 Anemia Tetrachlorodibenzodioxin 8.4811748828
MESH:D000743 Anemia, Hemolytic Quercetin 4.1817084956
MESH:D001008 Anxiety Disorders vinclozolin 3.5819015723
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 4.0119183758
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 3.4011256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 2.6215885639
MESH:D001260 Ataxia Telangiectasia Quercetin 4.9215336622
MESH:D050197 Atherosclerosis Phenytoin 3.8815136057
MESH:D001327 Autoimmune Diseases Quercetin 4.3419761891
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 2.9812125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.7315340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.7215746008
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 2.3117474063 20146248
MESH:D001943 Breast Neoplasms Estradiol 2.3117289903 14630087 17261762 18497071 12948864 16675129 17018787 19861407
MESH:D001943 Breast Neoplasms Fluorouracil 2.3118357371 16595493 19217205 15136595 16557594 18608205 16110121
MESH:D001943 Breast Neoplasms Quercetin 2.3118628248
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 2.3120435547
MESH:D002105 Cadmium Poisoning Quercetin 5.4916962696
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 4.4016111702
MESH:D002252 Carbon Tetrachloride Poisoning Vitamin E 3.8716050911
MESH:D002276 Carcinoid Tumor Fluorouracil 4.6116051944
MESH:D002277 Carcinoma Fluorouracil 8.0017121937
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 8.0016835633
MESH:D006528 Carcinoma, Hepatocellular 2,4-dinitrotoluene 8.7716705839
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 8.7716705839
MESH:D006528 Carcinoma, Hepatocellular Estradiol 8.7716924424
MESH:D006528 Carcinoma, Hepatocellular Fluorouracil 8.7717971768 17045692 18930000 17088986 16799960 16332177
MESH:D006528 Carcinoma, Hepatocellular Quercetin 8.7712508355 19519916
MESH:D021441 Carcinoma, Pancreatic Ductal Quercetin 4.8917234771
MESH:D002292 Carcinoma, Renal Cell Fluorouracil 2.9918695887
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 4.5820419170
MESH:D002294 Carcinoma, Squamous Cell Fluorouracil 4.5816280240 18986760 16757204 17066447
MESH:D006332 Cardiomegaly Quercetin 6.6819794523
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 6.6818670907 16120746 18850075
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 10.906135515
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 10.9020889678
MESH:D002471 Cell Transformation, Neoplastic Estradiol 10.9018566989
MESH:D002493 Central Nervous System Diseases Phenytoin 5.234080065
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 3.1016835633
MESH:D002779 Cholestasis Ethinyl Estradiol 2.8217681005 16919318 17110522 15861022 11677210 16105132 17333356
OMIM:601042 CHOREOATHETOSIS/SPASTICITY, EPISODIC Phenytoin 5.8111748493
MESH:D002971 Cleft Lip Phenytoin 4.122227380
MESH:D002972 Cleft Palate Phenytoin 6.0710789828 3877104 2227380 6862529 6856622 1687470
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 6.078697196 16354765 15668235 12621046 15340226
MESH:D003092 Colitis Selenium 3.7217936198
MESH:D003103 Coloboma Phenytoin 5.099212184
MESH:D003110 Colonic Neoplasms Fluorouracil 3.8617169374 18772588 16340194 17725105 17172411 16510598 17016597 15001691 17287894 17018589
MESH:D003110 Colonic Neoplasms Quercetin 3.8611134977 19440933 17191121 17148506 15741050 19056647 16640504
MESH:D015179 Colorectal Neoplasms Fluorouracil 2.6516303861 17695437 14970324 18802399 17454858 16282729 15289873 16331619 15148649 18383874 18288408 16524972 17016601 20501625 17594712 18949393 18509181 17094418 17255274 16391804 18448328 17401013
MESH:D015179 Colorectal Neoplasms Quercetin 2.6518095365 18852136
MESH:D000013 Congenital Abnormalities Phenytoin 9.1910627286
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 9.1914669216 17141729
MESH:D019465 Craniofacial Abnormalities Phenytoin 3.8719952982 8986270 9212184
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 3.8715322242 10048152 20055451
MESH:D019465 Craniofacial Abnormalities Vitamin E 3.8719769572
MESH:D003456 Cryptorchidism vinclozolin 4.2814966744
MESH:D003490 Cyanosis 2,4-dinitrotoluene 10.6818551238
MESH:D003490 Cyanosis 2,6-dinitrotoluene 10.6818551238
MESH:D007644 Darier Disease Fluorouracil 4.7316733453
MESH:D003921 Diabetes Mellitus, Experimental Quercetin 3.6819496084
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 1.6517107852
MESH:D003928 Diabetic Nephropathies Estradiol 3.3519279558
OMIM:607208 DRAVET SYNDROME Phenytoin 5.3211748493
MESH:D003875 Drug Eruptions Phenytoin 5.4415024534
MESH:D056486 Drug-Induced Liver Injury 2,4-dinitrotoluene 8.8118551238 21346803
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 8.8121346803 18551238
MESH:D056486 Drug-Induced Liver Injury Selenium 8.8115131321
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 8.8120420201
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.7111462148
MESH:C538011 Eales disease Vitamin E 4.659068938
MESH:D004487 Edema Tetrachlorodibenzodioxin 2.3212711302 11000095
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 3.8518230668 16714409 15322242
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 9.1512538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Phenytoin 9.1517654737
MESH:D016889 Endometrial Neoplasms Estradiol 2.9419148513 11473722 18566989
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 2.969294722 10568697
MESH:D004816 Epidermal Necrolysis, Toxic Phenytoin 5.1320235791
MESH:D004820 Epidermolysis Bullosa Phenytoin 6.186251365 1399206
MESH:D004828 Epilepsies, Partial Phenytoin 4.8611558140 17116037
MESH:D004827 Epilepsy Phenytoin 3.9020417680 11434505 821787
MESH:D017029 Epilepsy, Complex Partial Phenytoin 5.237750514
MESH:D004830 Epilepsy, Tonic-Clonic Phenytoin 5.003659116
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 10.2820426865
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 10.2816530937
MESH:D004938 Esophageal Neoplasms Fluorouracil 10.2815173087 16785472 17638652 16481741 16337965
MESH:D004938 Esophageal Neoplasms nitrosobenzylmethylamine 10.2816704527 15878914 15547721 15150132 15547733 16805852 16510608 15623463 15264214
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 2.9611564622
MESH:D005234 Fatty Liver Ethinyl Estradiol 2.7515345470
MESH:D005313 Fetal Death Phenytoin 10.5310627286
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 10.5311858732
MESH:D005355 Fibrosis Quercetin 8.5519474275
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 8.5520067830
MESH:D030342 Genetic Diseases, Inborn vinclozolin 4.8716973722
MESH:D005832 Genital Diseases, Male vinclozolin 5.2416417039
MESH:D005885 Gingival Hyperplasia Phenytoin 5.609029455
MESH:D019214 Gingival Overgrowth Phenytoin 6.1814659971 16390469
MESH:D005909 Glioblastoma Quercetin 3.3519804834
MESH:D005910 Glioma Fluorouracil 6.1016145905
MESH:D005910 Glioma Quercetin 6.1017643826
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.5410696789
MESH:D006258 Head and Neck Neoplasms Fluorouracil 3.3415102660 18337622 15162350
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 10.9020471113
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 10.9010048152 11294989
MESH:D006330 Heart Defects, Congenital Vitamin E 10.9016080930
MESH:D006333 Heart Failure Selenium 3.0317162251
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.2711000095
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 2.8316120746 15340226 12621046
MESH:D006548 Hernia, Diaphragmatic Vitamin E 2.6816863852 16490937
MESH:D006558 Herpes Genitalis Estradiol 4.9815709030
MESH:D019584 Hot Flashes Estradiol 9.8617088409
MESH:D019584 Hot Flashes Vitamin E 9.8614716179
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.9918606429 8697196 16354765 15340226 16959395
MESH:D006943 Hyperglycemia Quercetin 3.9711834736 18262572
MESH:D020138 Hyperhomocysteinemia Phenytoin 4.6110459572
MESH:D006973 Hypertension Quercetin 5.1418356687
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 5.1418670907 18850075
MESH:D007021 Hypospadias Ethinyl Estradiol 3.7516569931 16945680
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.4012013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 6.5117937319
MESH:D007248 Infertility, Male vinclozolin 6.5116467254
MESH:D007249 Inflammation Flavonoids 4.8817296493
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 4.8812878042 12200463
MESH:D007251 Influenza, Human Quercetin 18.3116624496
MESH:D007251 Influenza, Human Selenium 18.3116624496
MESH:D007251 Influenza, Human Vitamin E 18.3116624496
MESH:D007333 Insulin Resistance Estradiol 2.9216627594 16393666
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 3.2716580747
MESH:D007627 Keloid Quercetin 4.8917086741
MESH:D007674 Kidney Diseases Estradiol 9.9415618244
MESH:D007674 Kidney Diseases Quercetin 9.9416962696
MESH:D007674 Kidney Diseases Vitamin E 9.9412488133
MESH:D007676 Kidney Failure, Chronic Selenium 3.8216518626
MESH:D007680 Kidney Neoplasms 2,4-dinitrotoluene 17.3116705839
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 17.3116705839
MESH:D007680 Kidney Neoplasms Estradiol 17.3115610895
MESH:D007680 Kidney Neoplasms Fluorouracil 17.3116985049
MESH:D007683 Kidney Tubular Necrosis, Acute Calcium 4.9916316344
MESH:D007938 Leukemia Quercetin 3.1217468513
MESH:D007984 Leydig Cell Tumor vinclozolin 4.6716417039
MESH:D054082 Lissencephaly marker/mechanism
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 4.9014659978 14716833
MESH:D008106 Liver Cirrhosis, Experimental Quercetin 4.9012741479
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 4.9012878042
MESH:D008106 Liver Cirrhosis, Experimental Vitamin E 4.9016169303
MESH:D008107 Liver Diseases Phenytoin 3.2014986274
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 13.987678174
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 13.9820195826 21137059
MESH:D008113 Liver Neoplasms Fluorouracil 13.9818383874 16603448 15113037 17045692
MESH:D008113 Liver Neoplasms Quercetin 13.9818980244
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 13.9816984957
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 9.606135515 2876786 2876784
MESH:D008114 Liver Neoplasms, Experimental Quercetin 9.6019519916
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 9.6012151625
MESH:D008171 Lung Diseases Vitamin E 3.1316863852
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 6.5120464547 6695378 20869020 18569708 20064080 17053015 18816296 18520028 20135361
MESH:D008175 Lung Neoplasms Fluorouracil 6.5115246190
MESH:D008175 Lung Neoplasms Quercetin 6.5116280456
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 6.5119555203 11884234
MESH:D008175 Lung Neoplasms Vitamin E 6.5111062179
MESH:D008178 Lupus Erythematosus, Cutaneous Fluorouracil 4.7315086387
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 5.8811408345 17203775 16891317 11807958
MESH:D008325 Mammary Neoplasms, Experimental Selenium 5.8815318939
MESH:D020149 Manganese Poisoning Estradiol 4.4319453300
MESH:D008607 Mental Retardation Phenytoin 3.659212184
MESH:D008654 Mesothelioma Selenium 2.7715107826
OMIM:247200 MILLER-DIEKER LISSENCEPHALY SYNDROME marker/mechanism
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 8.3616381670
MESH:D009062 Mouth Neoplasms Fluorouracil 8.3616757204 18986760
MESH:D009203 Myocardial Infarction Quercetin 2.9619595682
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 2.9612213967
MESH:D015428 Myocardial Reperfusion Injury Estradiol 8.3916810080
MESH:D015428 Myocardial Reperfusion Injury Quercetin 8.3919207477
MESH:D020191 Myoclonic Epilepsies, Progressive Phenytoin 5.4617484760
MESH:D009224 Myotonia Congenita Phenytoin 5.351896199
MESH:D009336 Necrosis 2,4-dinitrotoluene 10.1418551238
MESH:D009336 Necrosis 2,6-dinitrotoluene 10.1418551238 7678174
MESH:D009369 Neoplasms Benzo(a)pyrene 8.1411141357
MESH:D009369 Neoplasms Fluorouracil 8.1416928823 18239605 18600527
MESH:D009369 Neoplasms Quercetin 8.1415185748
MESH:D009389 Neovascularization, Pathologic Estradiol 3.6717289903
MESH:D009421 Nervous System Malformations Estradiol 9.2516427766 11399458
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 9.2514600291
MESH:D009436 Neural Tube Defects Phenytoin 4.089118846
MESH:D020078 Neurogenic Inflammation Quercetin 4.3017929310
MESH:D020258 Neurotoxicity Syndromes Fluorouracil 3.3916436463
MESH:D009784 Occupational Diseases 2,4-dinitrotoluene 8.6912819281 16049721
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 8.6916049721
MESH:D010018 Osteomalacia Phenytoin 5.3517016548
MESH:D010024 Osteoporosis Calcium 3.7417882678
MESH:D015663 Osteoporosis, Postmenopausal Quercetin 4.1619495926
MESH:D010051 Ovarian Neoplasms Estradiol 4.8819401270
MESH:D010051 Ovarian Neoplasms Quercetin 4.8819005980
MESH:D010146 Pain Phenytoin 3.9215215642
MESH:D010190 Pancreatic Neoplasms Fluorouracil 5.4016929163 19003803 15113037 16500647
MESH:D010190 Pancreatic Neoplasms Quercetin 5.4016965848
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.6211578682
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.1912520081
MESH:D010954 Plasmacytoma Selenium 4.8315087411
MESH:D017689 Polydactyly Phenytoin 4.989212184
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.4918163543
MESH:D011230 Precancerous Conditions Quercetin 3.9219056647
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 9.2811118676 11896295 11222880 11399792
MESH:D011297 Prenatal Exposure Delayed Effects vinclozolin 9.2819015723 18220299 18042343
MESH:D011469 Prostatic Diseases vinclozolin 4.8718220299
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 3.8220887781
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 1.8717292933
MESH:D011471 Prostatic Neoplasms Estradiol 1.8716740699
MESH:D011471 Prostatic Neoplasms Fluorouracil 1.8719082440 18626508
MESH:D011471 Prostatic Neoplasms Quercetin 1.8717292933 14715546
MESH:D011471 Prostatic Neoplasms Vitamin E 1.8715084515
MESH:D011472 Prostatitis vinclozolin 4.8718629315
MESH:D011537 Pruritus Ethinyl Estradiol 3.2515861022 16919318
MESH:D019310 Pseudolymphoma Phenytoin 5.498603615 12752131 1419762
MESH:D012004 Rectal Neoplasms Fluorouracil 3.9518722050 15538739 18286688 16160472
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.7718990726
MESH:D012554 Schistosomiasis japonica Quercetin 5.4916862918
MESH:D012640 Seizures 2,4-dinitrotoluene 9.6918551238
MESH:D012640 Seizures 2,6-dinitrotoluene 9.6918551238
MESH:D012640 Seizures Phenytoin 9.699844417 10029267 3137016 11044598 3691417 15946322 19919933 16876388
MESH:D012871 Skin Diseases Vitamin E 2.4218709164
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 9.2219755658 10029692
MESH:D012878 Skin Neoplasms tert-Butylhydroperoxide 9.228532709
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 9.2216192470
MESH:D013088 Spermatocele Ethinyl Estradiol 3.8916709447
MESH:D013262 Stevens-Johnson Syndrome Phenytoin 5.0920235791
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 3.4020155912 2093021
MESH:D013274 Stomach Neoplasms Fluorouracil 3.4018396642 19015929 17172411 17498489 15786421 18567086 16951190 16424979 17522103 19084572
MESH:D013274 Stomach Neoplasms nitrosobenzylmethylamine 3.4012958204 17575124
MESH:D020521 Stroke Vitamin E 3.4716517955
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.5611994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.0915669648
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.8512697716
MESH:D013978 Tibial Fractures Estradiol 4.6319048282
MESH:D014062 Tongue Neoplasms Fluorouracil 3.9316280240
MESH:D001749 Urinary Bladder Neoplasms 2,4-dinitrotoluene 11.7216049721
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 11.7216049721
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 11.7217053015
MESH:D001749 Urinary Bladder Neoplasms Quercetin 11.7216720314
MESH:D014571 Urologic Neoplasms 2,4-dinitrotoluene 11.7810091137
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 11.7810091137
MESH:D002583 Uterine Cervical Neoplasms Fluorouracil 3.8216803524
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 3.2314692618
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.5412125929
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.4814671159 15869587
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.1915886252
Pathway ID Pathway Name
REACT:152 Cell Cycle, Mitotic
REACT:383 DNA Replication
KEGG:00565 Ether lipid metabolism
KEGG:01100 Metabolic pathways
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA32905
    • No data
    No data
    Releated drug ID Related drug Name
    PA152241909PP2
    Drug Bank Top
    Drugbank ID Action Drug Name Description
    DB04184 - Acetate Ion Indicators and Reagents
    No data
    No data
    No data

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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