AutismKB 2.0

Annotation Detail for NOX3


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Basic Information Top
Gene Symbol:NOX3 ( GP91-3,MOX-2 )
Gene Full Name: NADPH oxidase 3
Band: 6q25.3
Quick LinksEntrez ID:50508; OMIM: 607105; Uniprot ID:NOX3_HUMAN; ENSEMBL ID: ENSG00000074771; HGNC ID: 7890
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa04670Leukocyte transendothelial migration
hsa04145Phagosome
No data
No data
No data
No data
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D019800 Phenol Phenol results in increased expression of NOX3 mRNAincreases expression 16785328
D011374 Progesterone Progesterone results in decreased expression of NOX3 mRNAdecreases expression 18070364
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D001859 Bone Neoplasms Phenol 5.8110556009
MESH:D001913 Bowen's Disease Phenol 6.8219293009
MESH:D020201 Brain Hemorrhage, Traumatic Progesterone 6.4117868700
MESH:D001930 Brain Injuries Progesterone 5.0215665606 15380490 15845082
MESH:D001943 Breast Neoplasms Progesterone 2.4017614352 15562024 16175315
MESH:D003929 Diabetic Neuropathies Progesterone 5.2617187935
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Progesterone 4.4517692515
MESH:D004715 Endometriosis Progesterone 4.2716134523
MESH:D020244 Infarction, Middle Cerebral Artery Progesterone 5.1715869954
MESH:D007249 Inflammation Progesterone 2.8115869954
MESH:D055623 Keratosis, Actinic Phenol 7.5119293009
MESH:D008325 Mammary Neoplasms, Experimental Progesterone 3.1517203775 11408345
MESH:D010051 Ovarian Neoplasms Progesterone 2.6316525653 17393432
MESH:D010146 Pain Phenol 4.6117610455
MESH:D010392 Pemphigus Phenol 7.5117163923 16522979
MESH:D010864 Pilonidal Sinus Phenol 7.5119655223 15622588
MESH:D011041 Poisoning Phenol 5.328825745
MESH:D012468 Salivary Gland Neoplasms Progesterone 2.9818045962
MESH:D013088 Spermatocele Phenol 6.7118646496
MESH:D013119 Spinal Cord Injuries Progesterone 5.1716503802 15862959
MESH:D014277 Trigeminal Neuralgia Phenol 7.5110223447 16527771
MESH:D014860 Warts Phenol 7.1719122958
Pathway ID Pathway Name
KEGG:04670 Leukocyte transendothelial migration
KEGG:04380 Osteoclast differentiation
KEGG:04145 Phagosome
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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