AutismKB 2.0

Annotation Detail for SERPINE1


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Basic Information Top
Gene Symbol:SERPINE1 ( PAI,PAI-1,PAI1,PLANH1 )
Gene Full Name: serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
Band: 7q22.1
Quick LinksEntrez ID:5054; OMIM: 173360; Uniprot ID:PAI1_HUMAN; ENSEMBL ID: ENSG00000106366; HGNC ID: 8583
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa05142Chagas disease
hsa04115p53 signaling pathway
hsa04610Complement and coagulation cascades
Pathway IDPathway Name
Hemostasis
Pathway IDPathway Name
200030HIF-2-alpha transcription factor network
200002Regulation of nuclear SMAD2/3 signaling
200027E2F transcription factor network
200172HIF-1-alpha transcription factor network
200101Direct p53 effectors
Pathway IDPathway Name
P00050Plasminogen activating cascade
P00059p53 pathway
P00011Blood coagulation
Pathway IDPathway Name
500304Dissolution of Fibrin Clot
Related Diseases/Disorders Top
Desease IDDesease Name
Circulatory system diseases
Hematologic diseases
H00223Inherited thrombophilia
Desease IDDesease Name
1706Thrombophilia
1753Hyperthyroidism
1770Melanoma
1781Rheumatoid arthritis
1788Infiltrating cancer
1822Infectious lung disease
1831Prostate cancer
1848Embryoma
1856Obesity
1859Ovarian cancer
1872Chronic simple glaucoma
1877Multiple sclerosis
1889Hyperinsulinism
1894Abortion
1904Diabetes mellitus
1944Breast cancer
1958Glomerulonephritis
1962Respiratory distress syndrome
2025Polyarthritis
1993Esophagus cancer
1997Dental plaque
1841Stomach cancer
2008Liver disease
2022Liver cancer
2040Hyperglycemia
2051Leukemia
2053Colon cancer
2066Lung cancer
2074Asthma
2102Polycystic ovary syndrome
2106Pancreas cancer
2111Systemic infection
2166Influenza
2196Periodontal disease
2197Metabolism disease
2214Malignant glioma
2232Aseptic necrosis of bone
2236Cardiovascular disease
2237Neoplasm metastasis
Desease Name
HEMATOLOGICAL
periodontitis
multiorgan failure septic shock mortality
oral cancer
cardiovascular disease
Thrombosis
coronary atherosclerosis
polycystic ovary syndrome
pneumonia
atherosclerosis, coronary
Cerebral Infarction
Fibromatosis, Aggressive
colorectal cancer
CARDIOVASCULAR
Coronary Artery Disease
myocardial infarct
endometriosis
prostate cancer
Lupus Nephritis
kidney dysfunction
CANCER
PSYCH
stroke, ischemic
plasminogen activator
bone density
kidney disease
Asthma
nephropathy in other diseases
asthma, dust mite-sensitive
aneurysm, abdominal aortic
RENAL
Cerebral Arterial Diseases
breast cancer
hypertension
Brain Ischemia
lumen loss, late
circadian variability in plasma PAI-1
cerebrovascular infart
lipoprotein, LDL
meningococcal disease
systemic lupus erythematosus
IMMUNE
decreased risk of cerebrovascular mortality
NEUROLOGICAL
gastric ulcer
pregnancy loss, recurrent
allergic disease, IgE mediated
METABOLIC
Stroke
Myocardial Infarction
Intracranial Embolism
VISION
chronic obstructive pulmonary disease/COPD
plasmatic PAI-1 activity
diabetes, gestational
coagulopathy
albuminuria retinopathy, diabetic
encephalopathy stroke
sudden cardiac death
obesity
depression
antiphospholipid syndrome
preeclampsia
PAI-1 levels
Crohn's disease
DEVELOPMENTAL
hypertension, pregnancy induced
coronary heart disease
thromboembolism, venous
cholesterol triglycerides
REPRODUCTION
limb deficiency anomalies
fibrinolytic activities
INFECTION
No data
Desease Name
Plasminogen activator inhibitor, type I
Transcription of plasminogen activator inhibitor, modulator of
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C548651 2-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester 2-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester results in increased expression of SERPINE1 mRNAincreases expression 19933214
C108123 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [Oxygen deficiency results in increased expression of SERPINE1 mRNA]decreases reaction|increases expression 15913578
C108123 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [Oxygen deficiency results in increased expression of SERPINE1 mRNA]decreases reaction|increases expression 15913578
D000082 Acetaminophen Acetaminophen affects the expression of SERPINE1 mRNAaffects expression 17562736
D000082 Acetaminophen Acetaminophen results in increased expression of SERPINE1 mRNAincreases expression 19420014
11264010
18469330
D000082 Acetaminophen SERPINE1 protein affects the reaction [Acetaminophen results in increased expression of CCND1 mRNA]affects reaction|increases expression 18469330
D000082 Acetaminophen SERPINE1 protein affects the reaction [Acetaminophen results in increased expression of CDKN1A mRNA]affects reaction|increases expression 18469330
D000082 Acetaminophen SERPINE1 protein affects the reaction [Acetaminophen results in increased expression of PCNA protein]affects reaction|increases expression 18469330
D000082 Acetaminophen SERPINE1 protein results in decreased susceptibility to Acetaminophendecreases response to substance 18469330
D016604 Aflatoxin B1 Aflatoxin B1 affects the expression of SERPINE1 proteinaffects expression 20106945
C412373 AG 1879 AG 1879 inhibits the reaction [Oxygen deficiency results in increased expression of SERPINE1 mRNA]decreases reaction|increases expression 15913578
C103303 alitretinoin alitretinoin inhibits the reaction [TGFB1 protein results in increased expression of SERPINE1 protein]decreases reaction|increases expression 16192631
D013196 Dihydrotestosterone bicalutamide inhibits the reaction [Dihydrotestosterone inhibits the reaction [Lipopolysaccharides results in increased expression of SERPINE1 mRNA]]decreases reaction|increases expression 16317058
D013196 Dihydrotestosterone Dihydrotestosterone inhibits the reaction [Lipopolysaccharides results in increased expression of SERPINE1 mRNA]decreases reaction|increases expression 16317058
D013196 Dihydrotestosterone Dihydrotestosterone inhibits the reaction [TNF protein results in increased expression of SERPINE1 mRNA]decreases reaction|increases expression 16317058
D000643 Ammonium Chloride Ammonium Chloride affects the expression of SERPINE1 mRNAaffects expression 16483693
C432165 anthra(1,9-cd)pyrazol-6(2H)-one anthra(1,9-cd)pyrazol-6(2H)-one inhibits the reaction [Catechin results in decreased expression of SERPINE1 mRNA]decreases expression|decreases reaction 17379280
C432165 anthra(1,9-cd)pyrazol-6(2H)-one anthra(1,9-cd)pyrazol-6(2H)-one inhibits the reaction [Quercetin results in decreased expression of SERPINE1 mRNA]decreases expression|decreases reaction 17379280
D001149 Arsenates [Atrazine co-treated with Arsenates] results in increased expression of SERPINE1 mRNAaffects cotreatment|increases expression 18585445
D001151 Arsenic Arsenic results in decreased expression of SERPINE1 mRNAdecreases expression 11134558
D001151 Arsenic Arsenic results in increased expression of SERPINE1 mRNAincreases expression 19945496
C006632 arsenic trioxide arsenic trioxide results in decreased expression of SERPINE1 mRNAdecreases expression 17530438
C015001 arsenite arsenite affects the expression of SERPINE1 mRNAaffects expression 15738583
C015001 arsenite [arsenite co-treated with Benzo(a)pyrene] results in decreased expression of SERPINE1 mRNAaffects cotreatment|decreases expression 15894712
C015001 arsenite arsenite results in decreased expression of SERPINE1 mRNAdecreases expression 15894712
D017638 Asbestos, Crocidolite Asbestos, Crocidolite results in increased expression of SERPINE1 mRNAincreases expression 17975199
18687144
D001280 Atrazine [Atrazine co-treated with Arsenates] results in increased expression of SERPINE1 mRNAaffects cotreatment|increases expression 18585445
D019324 beta-Naphthoflavone beta-Naphthoflavone results in increased expression of SERPINE1 mRNAincreases expression 19737606
D019324 beta-Naphthoflavone [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of SERPINE1 mRNAaffects cotreatment|increases expression 18164116
20045035
21295105
D019324 beta-Naphthoflavone isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of SERPINE1 mRNA]affects cotreatment|decreases reaction|increases expression 20045035
D001564 Benzo(a)pyrene Benzo(a)pyrene results in increased expression of SERPINE1 mRNAincreases expression 20106945
D001564 Benzo(a)pyrene [arsenite co-treated with Benzo(a)pyrene] results in decreased expression of SERPINE1 mRNAaffects cotreatment|decreases expression 15894712
D001564 Benzo(a)pyrene Benzo(a)pyrene results in decreased expression of SERPINE1 mRNAdecreases expression 15894712
D001629 Bezafibrate Bezafibrate results in increased expression of SERPINE1 mRNAincreases expression 17118139
C053541 bicalutamide bicalutamide inhibits the reaction [Dihydrotestosterone inhibits the reaction [Lipopolysaccharides results in increased expression of SERPINE1 mRNA]]decreases reaction|increases expression 16317058
C074619 bivalirudin bivalirudin inhibits the reaction [F2 protein results in increased expression of SERPINE1 mRNA]decreases reaction|increases expression 9579636
9125671
C074619 bivalirudin bivalirudin inhibits the reaction [F2 protein results in increased expression of SERPINE1 protein]decreases reaction|increases expression 9579636
C074619 bivalirudin bivalirudin inhibits the reaction [F2 protein results in increased secretion of SERPINE1 protein]decreases reaction|increases secretion 9125671
D015124 8-Bromo Cyclic Adenosine Monophosphate 8-Bromo Cyclic Adenosine Monophosphate inhibits the reaction [F2 protein results in increased expression of SERPINE1 protein]decreases reaction|increases expression 9579636
D002084 Butylated Hydroxytoluene Butylated Hydroxytoluene inhibits the reaction [LPA protein results in decreased expression of SERPINE1 protein]decreases expression|decreases reaction 10856522
D002084 Butylated Hydroxytoluene Butylated Hydroxytoluene inhibits the reaction [LPA protein results in increased expression of SERPINE1 protein]decreases reaction|increases expression 10856522
D020122 tert-Butylhydroperoxide tert-Butylhydroperoxide results in increased expression of SERPINE1 mRNAincreases expression 15336504
D002104 Cadmium Cadmium results in increased expression of SERPINE1 mRNAincreases expression 21172416
D002251 Carbon Tetrachloride Carbon Tetrachloride results in decreased expression of SERPINE1 mRNAdecreases expression 16239168
D002251 Carbon Tetrachloride Carbon Tetrachloride results in increased expression of SERPINE1 mRNAincreases expression 12445421
D002251 Carbon Tetrachloride pirfenidone inhibits the reaction [Carbon Tetrachloride results in increased expression of SERPINE1 mRNA]decreases reaction|increases expression 12445421
D002259 Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of SERPINE1 mRNAdecreases expression 16039398
D002392 Catechin anthra(1,9-cd)pyrazol-6(2H)-one inhibits the reaction [Catechin results in decreased expression of SERPINE1 mRNA]decreases expression|decreases reaction 17379280
D002392 Catechin Catechin results in decreased expression of SERPINE1 mRNAdecreases expression 17379280
D002392 Catechin U 0126 inhibits the reaction [Catechin results in decreased expression of SERPINE1 mRNA]decreases expression|decreases reaction 17379280
D002713 Chlorine Chlorine results in increased expression of SERPINE1 mRNAincreases expression 18636392
D002713 Chlorine [Ozone co-treated with Chlorine] affects the expression of SERPINE1 mRNAaffects cotreatment|affects expression 18636392
D002794 Choline Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of SERPINE1 mRNA]affects cotreatment|decreases reaction|increases expression 19593819
D002794 Choline [Methionine deficiency co-treated with Choline deficiency] results in increased expression of SERPINE1 mRNAaffects cotreatment|increases expression 19593819
D002794 Choline [Methionine deficiency co-treated with Choline deficiency] results in increased expression of SERPINE1 proteinaffects cotreatment|increases expression 19593819
D002794 Choline NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of SERPINE1 mRNA]]affects cotreatment|decreases reaction|increases expression|increases reaction 19593819
D002794 Choline pirinixic acid inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of SERPINE1 mRNA]affects cotreatment|decreases reaction|increases expression 19593819
D003474 Curcumin Curcumin results in increased expression of SERPINE1 mRNAincreases expression 15713895
D003513 Cycloheximide Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of SERPINE1 mRNA]decreases reaction|increases expression 11007951
D003513 Cycloheximide Cycloheximide promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of SERPINE1 mRNA]increases expression|increases reaction 12111005
D016572 Cyclosporine Cyclosporine results in increased expression of SERPINE1 mRNAincreases expression 20106945
C014347 decitabine decitabine results in increased expression of SERPINE1 mRNAincreases expression 16367923
D013759 Tetrahydrocannabinol Tetrahydrocannabinol results in increased expression of SERPINE1 mRNAincreases expression 16039398
D003907 Dexamethasone [Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of SERPINE1 mRNAaffects cotreatment|increases expression 16054899
D003907 Dexamethasone Tetrachlorodibenzodioxin inhibits the reaction [[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of SERPINE1 mRNA]affects cotreatment|decreases reaction|increases expression 16054899
D003907 Dexamethasone Dexamethasone promotes the reaction [IL1B protein results in increased expression of SERPINE1 protein]increases expression|increases reaction 15963473
C023635 dienogest [Ethinyl Estradiol co-treated with dienogest] results in decreased expression of SERPINE1 proteinaffects cotreatment|decreases expression 15288212
D004052 Diethylnitrosamine AHR protein inhibits the reaction [Diethylnitrosamine results in increased expression of SERPINE1 mRNA]decreases reaction|increases expression 19996281
D004052 Diethylnitrosamine Diethylnitrosamine affects the expression of SERPINE1 mRNAaffects expression 21159647
D004052 Diethylnitrosamine Diethylnitrosamine affects the expression of SERPINE1 proteinaffects expression 21159647
D004052 Diethylnitrosamine Diethylnitrosamine results in increased expression of SERPINE1 mRNAincreases expression 19996281
18282651
D004052 Diethylnitrosamine RB1 protein promotes the reaction [Diethylnitrosamine results in increased expression of SERPINE1 mRNA]increases expression|increases reaction 18282651
D004052 Diethylnitrosamine [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of SERPINE1 mRNAaffects cotreatment|increases expression 21295105
18164116
20045035
D004052 Diethylnitrosamine [Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of SERPINE1 mRNAaffects cotreatment|increases expression 18253720
D004052 Diethylnitrosamine isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of SERPINE1 mRNA]affects cotreatment|decreases reaction|increases expression 20045035
D004178 Diquat Diquat results in increased expression of SERPINE1 mRNAincreases expression 21172416
D004317 Doxorubicin Doxorubicin results in decreased expression of SERPINE1 mRNAdecreases expression 16705698
D004317 Doxorubicin Doxorubicin results in increased expression of SERPINE1 mRNAincreases expression 15870702
D004317 Doxorubicin SERPINE1 protein affects the susceptibility to Doxorubicinaffects response to substance 16217747
D004837 Epinephrine Epinephrine results in increased expression of SERPINE1 mRNAincreases expression 15850565
D004958 Estradiol [Estradiol co-treated with Tetrachlorodibenzodioxin] results in decreased expression of SERPINE1 mRNAaffects cotreatment|decreases expression 19619570
D004958 Estradiol Estradiol results in increased expression of SERPINE1 mRNAincreases expression 20106945
19619570
D004958 Estradiol [Progesterone co-treated with Estradiol] results in increased expression of SERPINE1 mRNAaffects cotreatment|increases expression 17404688
C454300 estradiol valerate-dienogest [Ethinyl Estradiol co-treated with estradiol valerate-dienogest] results in decreased expression of SERPINE1 proteinaffects cotreatment|decreases expression 15288212
D004966 Estrogens, Conjugated (USP) Estrogens, Conjugated (USP) results in decreased expression of SERPINE1 proteindecreases expression 15850603
D004997 Ethinyl Estradiol [Ethinyl Estradiol binds to Norethindrone] which results in decreased expression of SERPINE1 proteinaffects binding|decreases expression 14561536
D004997 Ethinyl Estradiol [Ethinyl Estradiol co-treated with dienogest] results in decreased expression of SERPINE1 proteinaffects cotreatment|decreases expression 15288212
D004997 Ethinyl Estradiol [Ethinyl Estradiol co-treated with estradiol valerate-dienogest] results in decreased expression of SERPINE1 proteinaffects cotreatment|decreases expression 15288212
D004997 Ethinyl Estradiol [Ethinyl Estradiol co-treated with Gestodene] results in increased activity of SERPINE1 proteinaffects cotreatment|increases activity 15504374
D004997 Ethinyl Estradiol [Ethinyl Estradiol co-treated with Levonorgestrel] results in decreased activity of SERPINE1 proteinaffects cotreatment|decreases activity 14981370
D004997 Ethinyl Estradiol [Ethinyl Estradiol co-treated with Levonorgestrel] results in decreased expression of SERPINE1 proteinaffects cotreatment|decreases expression 15157790
15288212
C442659 ethinyl estradiol-desogestrel combination ethinyl estradiol-desogestrel combination results in decreased activity of SERPINE1 proteindecreases activity 14981370
D011345 Fenofibrate Fenofibrate inhibits the reaction [NR4A1 protein results in increased expression of SERPINE1 mRNA]decreases reaction|increases expression 19593819
D011345 Fenofibrate Fenofibrate inhibits the reaction [SMAD3 protein results in increased expression of SERPINE1 mRNA]decreases reaction|increases expression 19593819
D011345 Fenofibrate Fenofibrate inhibits the reaction [SMAD4 protein results in increased expression of SERPINE1 mRNA]decreases reaction|increases expression 19593819
D011345 Fenofibrate Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of SERPINE1 mRNA]decreases reaction|increases expression 19593819
D011345 Fenofibrate Fenofibrate inhibits the reaction [TNF protein results in increased expression of SERPINE1 mRNA]decreases reaction|increases expression 19593819
D011345 Fenofibrate NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [NR4A1 protein results in increased expression of SERPINE1 mRNA]]decreases reaction|increases expression|increases reaction 19593819
D011345 Fenofibrate NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [SMAD3 protein results in increased expression of SERPINE1 mRNA]]decreases reaction|increases expression|increases reaction 19593819
D011345 Fenofibrate NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [SMAD4 protein results in increased expression of SERPINE1 mRNA]]decreases reaction|increases expression|increases reaction 19593819
D011345 Fenofibrate NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of SERPINE1 mRNA]]decreases reaction|increases expression|increases reaction 19593819
D011345 Fenofibrate NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [TNF protein results in increased expression of SERPINE1 mRNA]]decreases reaction|increases expression|increases reaction 19593819
D011345 Fenofibrate Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of SERPINE1 mRNA]affects cotreatment|decreases reaction|increases expression 19593819
D011345 Fenofibrate Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of SERPINE1 mRNA]decreases reaction|increases expression 19593819
D011345 Fenofibrate NR0B2 protein inhibits the reaction [Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of SERPINE1 mRNA]]decreases reaction|increases expression 19593819
D011345 Fenofibrate NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of SERPINE1 mRNA]]affects cotreatment|decreases reaction|increases expression|increases reaction 19593819
D011345 Fenofibrate [Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of SERPINE1 mRNAaffects cotreatment|increases expression 18253720
D005576 Forskolin Forskolin inhibits the reaction [F2 protein results in increased expression of SERPINE1 protein]decreases reaction|increases expression 9579636
D005632 Fructose Fructose results in increased secretion of SERPINE1 proteinincreases secretion 19165636
D005688 Galactosamine Galactosamine results in increased expression of SERPINE1 mRNAincreases expression 11779202
C033273 Gestodene [Ethinyl Estradiol co-treated with Gestodene] results in increased activity of SERPINE1 proteinaffects cotreatment|increases activity 15504374
D005947 Glucose Glucose results in increased secretion of SERPINE1 proteinincreases secretion 16320596
D005947 Glucose Indomethacin inhibits the reaction [Glucose results in increased secretion of SERPINE1 protein]decreases reaction|increases secretion 16320596
D006145 Guanethidine Guanethidine inhibits the reaction [Kainic Acid results in increased expression of SERPINE1 mRNA]decreases reaction|increases expression 15850565
D006851 Hydrochloric Acid SERPINE1 protein affects the susceptibility to Hydrochloric Acidaffects response to substance 19060228
D007213 Indomethacin Indomethacin inhibits the reaction [Glucose results in increased secretion of SERPINE1 protein]decreases reaction|increases secretion 16320596
D007213 Indomethacin Indomethacin inhibits the reaction [Lipopolysaccharides results in increased secretion of SERPINE1 protein]decreases reaction|increases secretion 16320596
D007213 Indomethacin Indomethacin results in increased expression of SERPINE1 mRNAincreases expression 16984733
D015056 1-Methyl-3-isobutylxanthine [Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of SERPINE1 mRNAaffects cotreatment|increases expression 16054899
D015056 1-Methyl-3-isobutylxanthine Tetrachlorodibenzodioxin inhibits the reaction [[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of SERPINE1 mRNA]affects cotreatment|decreases reaction|increases expression 16054899
C016527 isoquercitrin isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of SERPINE1 mRNA]affects cotreatment|decreases reaction|increases expression 20045035
D007608 Kainic Acid Guanethidine inhibits the reaction [Kainic Acid results in increased expression of SERPINE1 mRNA]decreases reaction|increases expression 15850565
D007608 Kainic Acid Kainic Acid results in increased expression of SERPINE1 mRNAincreases expression 15850565
D007608 Kainic Acid Mecamylamine inhibits the reaction [Kainic Acid results in increased expression of SERPINE1 mRNA]decreases reaction|increases expression 15850565
D007608 Kainic Acid Phentolamine inhibits the reaction [Kainic Acid results in increased expression of SERPINE1 mRNA]decreases reaction|increases expression 15850565
D008070 Lipopolysaccharides bicalutamide inhibits the reaction [Dihydrotestosterone inhibits the reaction [Lipopolysaccharides results in increased expression of SERPINE1 mRNA]]decreases reaction|increases expression 16317058
D008070 Lipopolysaccharides Dihydrotestosterone inhibits the reaction [Lipopolysaccharides results in increased expression of SERPINE1 mRNA]decreases reaction|increases expression 16317058
D008070 Lipopolysaccharides Indomethacin inhibits the reaction [Lipopolysaccharides results in increased secretion of SERPINE1 protein]decreases reaction|increases secretion 16320596
D008070 Lipopolysaccharides Lipopolysaccharides results in increased expression of SERPINE1 mRNAincreases expression 16317058
D008070 Lipopolysaccharides Lipopolysaccharides results in increased secretion of SERPINE1 proteinincreases secretion 16320596
D008070 Lipopolysaccharides Lipopolysaccharides results in increased expression of SERPINE1 mRNAincreases expression 11779202
C013592 mangiferin mangiferin inhibits the reaction [AGT protein results in increased expression of SERPINE1 mRNA]decreases reaction|increases expression 19706694
D008464 Mecamylamine Mecamylamine inhibits the reaction [Kainic Acid results in increased expression of SERPINE1 mRNA]decreases reaction|increases expression 15850565
D017258 Medroxyprogesterone Acetate Medroxyprogesterone Acetate results in increased expression of SERPINE1 proteinincreases expression 16011840
D008715 Methionine Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of SERPINE1 mRNA]affects cotreatment|decreases reaction|increases expression 19593819
D008715 Methionine [Methionine deficiency co-treated with Choline deficiency] results in increased expression of SERPINE1 mRNAaffects cotreatment|increases expression 19593819
D008715 Methionine [Methionine deficiency co-treated with Choline deficiency] results in increased expression of SERPINE1 proteinaffects cotreatment|increases expression 19593819
D008715 Methionine NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of SERPINE1 mRNA]]affects cotreatment|decreases reaction|increases expression|increases reaction 19593819
D008715 Methionine pirinixic acid inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of SERPINE1 mRNA]affects cotreatment|decreases reaction|increases expression 19593819
D008748 Methylcholanthrene Methylcholanthrene results in increased expression of SERPINE1 mRNAincreases expression 16619036
D008769 Methylnitronitrosoguanidine Methylnitronitrosoguanidine results in increased expression of SERPINE1 mRNAincreases expression 15120970
D015735 Mifepristone Mifepristone results in decreased expression of SERPINE1 mRNAdecreases expression 17584828
D015735 Mifepristone Mifepristone promotes the reaction [IL1B protein results in increased expression of SERPINE1 protein]increases expression|increases reaction 15963473
D016685 Mitomycin SERPINE1 protein affects the susceptibility to Mitomycinaffects response to substance 16217747
C406082 monomethylarsonous acid monomethylarsonous acid results in increased expression of SERPINE1 mRNAincreases expression 19945496
D009532 Nickel HIF1A protein promotes the reaction [Nickel results in increased expression of SERPINE1 mRNA]increases expression|increases reaction 11504687
D009532 Nickel Nickel results in increased expression of SERPINE1 mRNAincreases expression 11504687
D009532 Nickel U 0126 inhibits the reaction [Nickel results in increased expression of SERPINE1 mRNA]decreases reaction|increases expression 11504687
C029938 nickel sulfate nickel sulfate results in increased expression of SERPINE1 mRNAincreases expression 16100012
D009640 Norethindrone [Ethinyl Estradiol binds to Norethindrone] which results in decreased expression of SERPINE1 proteinaffects binding|decreases expression 14561536
D016912 Levonorgestrel [Ethinyl Estradiol co-treated with Levonorgestrel] results in decreased activity of SERPINE1 proteinaffects cotreatment|decreases activity 14981370
D016912 Levonorgestrel [Ethinyl Estradiol co-treated with Levonorgestrel] results in decreased expression of SERPINE1 proteinaffects cotreatment|decreases expression 15157790
15288212
C516519 NuvaRing NuvaRing results in decreased expression of SERPINE1 proteindecreases expression 15157790
D019787 Linoleic Acid Linoleic Acid results in increased expression of SERPINE1 mRNAincreases expression 17374693
D010100 Oxygen 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [Oxygen deficiency results in increased expression of SERPINE1 mRNA]decreases reaction|increases expression 15913578
D010100 Oxygen AG 1879 inhibits the reaction [Oxygen deficiency results in increased expression of SERPINE1 mRNA]decreases reaction|increases expression 15913578
D010100 Oxygen Oxygen deficiency results in increased expression of SERPINE1 mRNAincreases expression 15913578
D010100 Oxygen Rotenone inhibits the reaction [Oxygen deficiency results in increased expression of SERPINE1 mRNA]decreases reaction|increases expression 15913578
D010100 Oxygen 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [Oxygen deficiency results in increased expression of SERPINE1 mRNA]decreases reaction|increases expression 15913578
D010100 Oxygen Oxygen deficiency results in increased expression of SERPINE1 mRNAincreases expression 15913578
D010126 Ozone Ozone results in increased expression of SERPINE1 mRNAincreases expression 19555225
D010126 Ozone [Ozone co-treated with Chlorine] affects the expression of SERPINE1 mRNAaffects cotreatment|affects expression 18636392
D017239 Paclitaxel SERPINE1 protein affects the susceptibility to Paclitaxelaffects response to substance 16217747
D019308 Palmitic Acid Palmitic Acid results in increased expression of SERPINE1 mRNAincreases expression 17658692
C084656 paricalcitol [Phosphorus co-treated with paricalcitol] affects the expression of SERPINE1 mRNAaffects cotreatment|affects expression 17715259
C084656 paricalcitol [Phosphorus co-treated with paricalcitol] results in decreased expression of SERPINE1 proteinaffects cotreatment|decreases expression 17715259
C023036 perfluorooctanoic acid perfluorooctanoic acid results in increased expression of SERPINE1 mRNAincreases expression 18467677
C023036 perfluorooctanoic acid PPARA protein promotes the reaction [perfluorooctanoic acid results in increased expression of SERPINE1 mRNA]increases expression|increases reaction 18467677
D010634 Phenobarbital Phenobarbital results in decreased expression of SERPINE1 mRNAdecreases expression 19270015
D010646 Phentolamine Phentolamine inhibits the reaction [Kainic Acid results in increased expression of SERPINE1 mRNA]decreases reaction|increases expression 15850565
D010656 Phenylephrine Phenylephrine results in increased expression of SERPINE1 mRNAincreases expression 15850565
D010656 Phenylephrine Phenylephrine results in increased expression of SERPINE1 mRNAincreases expression 15808835
D010758 Phosphorus [Phosphorus co-treated with paricalcitol] affects the expression of SERPINE1 mRNAaffects cotreatment|affects expression 17715259
D010758 Phosphorus [Phosphorus co-treated with paricalcitol] results in decreased expression of SERPINE1 proteinaffects cotreatment|decreases expression 17715259
C004479 pimagedine pimagedine inhibits the reaction [LPA protein modified form results in increased expression of SERPINE1 protein]decreases reaction|increases expression 10856522
C004479 pimagedine pimagedine results in increased expression of SERPINE1 mRNAincreases expression 18380797
C093844 pirfenidone pirfenidone inhibits the reaction [Carbon Tetrachloride results in increased expression of SERPINE1 mRNA]decreases reaction|increases expression 12445421
C006253 pirinixic acid [pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of SERPINE1 mRNAaffects binding|increases activity|increases expression 19710929
C006253 pirinixic acid pirinixic acid inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of SERPINE1 mRNA]affects cotreatment|decreases reaction|increases expression 19593819
C006253 pirinixic acid pirinixic acid results in increased expression of SERPINE1 mRNAincreases expression 17118139
D010936 Plant Extracts Plant Extracts inhibits the reaction [AGT protein results in increased expression of SERPINE1 mRNA]decreases reaction|increases expression 19706694
D011374 Progesterone [Progesterone co-treated with Estradiol] results in increased expression of SERPINE1 mRNAaffects cotreatment|increases expression 17404688
D011374 Progesterone Progesterone results in increased expression of SERPINE1 mRNAincreases expression 17404688
D011372 Progestins Progestins results in increased expression of SERPINE1increases expression 16011840
D011794 Quercetin anthra(1,9-cd)pyrazol-6(2H)-one inhibits the reaction [Quercetin results in decreased expression of SERPINE1 mRNA]decreases expression|decreases reaction 17379280
D011794 Quercetin Quercetin results in decreased expression of SERPINE1 mRNAdecreases expression 17379280
D011794 Quercetin U 0126 inhibits the reaction [Quercetin results in decreased expression of SERPINE1 mRNA]decreases expression|decreases reaction 17379280
D020849 Raloxifene [Raloxifene co-treated with ESR2 protein] results in increased expression of SERPINE1 mRNAaffects cotreatment|increases expression 19059307
D020849 Raloxifene Raloxifene results in decreased expression of SERPINE1 proteindecreases expression 15850603
D020849 Raloxifene Raloxifene results in increased expression of SERPINE1 proteinincreases expression 16277677
C059514 resveratrol resveratrol inhibits the reaction [stearic acid results in increased expression of SERPINE1 mRNA]decreases reaction|increases expression 17374693
C059514 resveratrol resveratrol inhibits the reaction [TNF protein results in increased expression of SERPINE1 mRNA]decreases reaction|increases expression 17967414
C059514 resveratrol resveratrol inhibits the reaction [TNF protein results in increased secretion of SERPINE1 protein]decreases reaction|increases secretion 17967414
D015474 Isotretinoin Isotretinoin results in decreased expression of SERPINE1 mRNAdecreases expression 15972972
C089730 rosiglitazone [Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of SERPINE1 mRNAaffects cotreatment|increases expression 16054899
C089730 rosiglitazone Tetrachlorodibenzodioxin inhibits the reaction [[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of SERPINE1 mRNA]affects cotreatment|decreases reaction|increases expression 16054899
D012402 Rotenone Rotenone inhibits the reaction [Oxygen deficiency results in increased expression of SERPINE1 mRNA]decreases reaction|increases expression 15913578
C423603 RU 24858 RU 24858 promotes the reaction [IL1B protein results in increased expression of SERPINE1 protein]increases expression|increases reaction 15963473
C085917 RU 43044 RU 43044 promotes the reaction [IL1B protein results in increased expression of SERPINE1 protein]increases expression|increases reaction 15963473
D012504 Saralasin Saralasin inhibits the reaction [AGT protein results in increased activity of SERPINE1 protein]decreases reaction|increases activity 11244025
C410733 scriptaid scriptaid affects the expression of SERPINE1 mRNAaffects expression 18813790
C430918 SEA 0400 SEA 0400 results in decreased expression of SERPINE1 mRNAdecreases expression 15215644
D019821 Simvastatin Simvastatin results in decreased expression of SERPINE1 mRNAdecreases expression 16375908
D019821 Simvastatin Simvastatin results in decreased expression of SERPINE1 proteindecreases expression 16375908
C017947 sodium arsenite sodium arsenite affects the expression of SERPINE1 mRNAaffects expression 16507464
C017947 sodium arsenite [sodium arsenite co-treated with Tetradecanoylphorbol Acetate] results in increased expression of SERPINE1 mRNAaffects cotreatment|increases expression 16368122
C017947 sodium arsenite [sodium arsenite co-treated with Tetradecanoylphorbol Acetate] results in increased expression of SERPINE1 proteinaffects cotreatment|increases expression 16368122
C017947 sodium arsenite sodium arsenite results in decreased expression of SERPINE1 mRNAdecreases expression 16014739
C017947 sodium arsenite sodium arsenite results in increased expression of SERPINE1 proteinincreases expression 16507464
C031183 stearic acid resveratrol inhibits the reaction [stearic acid results in increased expression of SERPINE1 mRNA]decreases reaction|increases expression 17374693
C031183 stearic acid stearic acid results in increased expression of SERPINE1 mRNAincreases expression 17374693
D013311 Streptozocin Streptozocin results in increased expression of SERPINE1 mRNAincreases expression 16973718
D013311 Streptozocin Trientine inhibits the reaction [Streptozocin results in increased expression of SERPINE1 mRNA]decreases reaction|increases expression 16973718
C025462 sulindac sulfide sulindac sulfide results in increased expression of SERPINE1 mRNAincreases expression 15897233
D013629 Tamoxifen [Tamoxifen co-treated with ESR2 protein] results in increased expression of SERPINE1 mRNAaffects cotreatment|increases expression 19059307
D013629 Tamoxifen Tamoxifen results in decreased expression of SERPINE1 proteindecreases expression 15850603
C084178 telmisartan telmisartan inhibits the reaction [AGT protein results in increased expression of SERPINE1 mRNA]decreases reaction|increases expression 19706694
D013749 Tetrachlorodibenzodioxin Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of SERPINE1 mRNA]decreases reaction|increases expression 11007951
D013749 Tetrachlorodibenzodioxin [Estradiol co-treated with Tetrachlorodibenzodioxin] results in decreased expression of SERPINE1 mRNAaffects cotreatment|decreases expression 19619570
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of SERPINE1 mRNAincreases expression 11489354
20106945
11007951
19619570
D013749 Tetrachlorodibenzodioxin AHR protein promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of SERPINE1 mRNA]increases expression|increases reaction 12111005
D013749 Tetrachlorodibenzodioxin AHR protein promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of SERPINE1 protein]increases expression|increases reaction 12111005
D013749 Tetrachlorodibenzodioxin ARNT protein promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of SERPINE1 mRNA]increases expression|increases reaction 12111005
D013749 Tetrachlorodibenzodioxin ARNT protein promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of SERPINE1 protein]increases expression|increases reaction 12111005
D013749 Tetrachlorodibenzodioxin Cycloheximide promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of SERPINE1 mRNA]increases expression|increases reaction 12111005
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin binds to AHR protein] which results in increased expression of SERPINE1 mRNAaffects binding|increases expression 16214954
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin inhibits the reaction [[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of SERPINE1 mRNA]affects cotreatment|decreases reaction|increases expression 16054899
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of SERPINE1 mRNAincreases expression 12167310
12111005
19933214
14728982
18796159
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of SERPINE1 proteinincreases expression 12111005
D013749 Tetrachlorodibenzodioxin CGA protein inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of SERPINE1 protein]decreases reaction|increases expression 12128104
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of SERPINE1 proteinincreases expression 12128104
D013755 Tetradecanoylphorbol Acetate [sodium arsenite co-treated with Tetradecanoylphorbol Acetate] results in increased expression of SERPINE1 mRNAaffects cotreatment|increases expression 16368122
D013755 Tetradecanoylphorbol Acetate [sodium arsenite co-treated with Tetradecanoylphorbol Acetate] results in increased expression of SERPINE1 proteinaffects cotreatment|increases expression 16368122
D013849 Thimerosal Thimerosal results in increased expression of SERPINE1 mRNAincreases expression 16870260
C027385 tibolone tibolone metabolite results in increased expression of SERPINE1 proteinincreases expression 16011840
C027385 tibolone tibolone results in increased expression of SERPINE1 proteinincreases expression 16011840
D014028 Tobacco Smoke Pollution Tobacco Smoke Pollution results in decreased expression of SERPINE1 mRNAdecreases expression 15289447
D019772 Topotecan SERPINE1 protein affects the susceptibility to Topotecanaffects response to substance 16217747
D014266 Trientine Trientine inhibits the reaction [Streptozocin results in increased expression of SERPINE1 mRNA]decreases reaction|increases expression 16973718
C009954 trilostane trilostane inhibits the reaction [GNRH1 protein results in increased expression of SERPINE1 mRNA]decreases reaction|increases expression 17332517
C113580 U 0126 U 0126 inhibits the reaction [Catechin results in decreased expression of SERPINE1 mRNA]decreases expression|decreases reaction 17379280
C113580 U 0126 U 0126 inhibits the reaction [Nickel results in increased expression of SERPINE1 mRNA]decreases reaction|increases expression 11504687
C113580 U 0126 U 0126 inhibits the reaction [Quercetin results in decreased expression of SERPINE1 mRNA]decreases expression|decreases reaction 17379280
C081489 valsartan valsartan inhibits the reaction [AGT protein results in increased secretion of SERPINE1 protein]decreases reaction|increases secretion 11244025
C081489 valsartan valsartan inhibits the reaction [AGT protein results in increased activity of SERPINE1 protein]decreases reaction|increases activity 11244025
C081489 valsartan valsartan inhibits the reaction [AGT protein results in increased expression of SERPINE1 mRNA]decreases reaction|increases expression 11244025
C081489 valsartan valsartan inhibits the reaction [AGT protein results in increased expression of SERPINE1 protein]decreases reaction|increases expression 11244025
D014747 Vinblastine SERPINE1 protein affects the susceptibility to Vinblastineaffects response to substance 16217747
D002762 Cholecalciferol Cholecalciferol results in increased expression of SERPINE1 mRNAincreases expression 17170073
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Tamoxifen 3.5814745880
MESH:D000014 Abnormalities, Drug-Induced Isotretinoin 8.9318769834
MESH:D000014 Abnormalities, Drug-Induced Phenobarbital 8.936195326
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 8.9311752688 14514962 15322242
MESH:D000015 Abnormalities, Multiple Isotretinoin 4.1118769834
MESH:D000138 Acidosis Ammonium Chloride 7.5818287403
MESH:D000138 Acidosis Hydrochloric Acid 7.5815920416 19262391 11574821 20872349 12771618 16144966
MESH:D000141 Acidosis, Renal Tubular Hydrochloric Acid 4.8317183249
MESH:D000142 Acidosis, Respiratory Hydrochloric Acid 4.8420597076
MESH:D017486 Acneiform Eruptions Isotretinoin 5.3116232082
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 8.7917505938
MESH:D000152 Acne Vulgaris Isotretinoin 8.7918769834 16185265
MESH:D000168 Acrocephalosyndactylia U 0126 4.5517694057
MESH:D054058 Acute Coronary Syndrome bivalirudin 5.4919804226 10629409
MESH:D058186 Acute Kidney Injury resveratrol 3.0016538975
MESH:D055371 Acute Lung Injury Chlorine 29.1920601635
MESH:D055371 Acute Lung Injury Hydrochloric Acid 29.1915970105 19060228 11953099 19094174 19760209 11850527 16759491
MESH:D055371 Acute Lung Injury Lipopolysaccharides 29.1918653653 11850527
MESH:D055371 Acute Lung Injury Nickel 29.1916166738
MESH:D055371 Acute Lung Injury nickel sulfate 29.1912718980 19131640 16100012 11954676
MESH:D055371 Acute Lung Injury Oxygen 29.1916759491
MESH:D055371 Acute Lung Injury pirinixic acid 29.1918653653
MESH:D000230 Adenocarcinoma arsenic trioxide 12.1511798837 19825857
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 12.1520127859 20464547
MESH:D000230 Adenocarcinoma Doxorubicin 12.1517418594
MESH:D000230 Adenocarcinoma Estradiol 12.1511473722
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 12.1514692618
MESH:D000230 Adenocarcinoma Indomethacin 12.1516537180
MESH:D002282 Adenocarcinoma, Bronchiolo-Alveolar Tobacco Smoke Pollution 4.5615814487
MESH:D000236 Adenoma Benzo(a)pyrene 17.876695378
MESH:D000236 Adenoma beta-Naphthoflavone 17.8719389873
MESH:D000236 Adenoma Diethylnitrosamine 17.876695378 10737359
MESH:D000236 Adenoma Indomethacin 17.8711497255
MESH:D000236 Adenoma Methylcholanthrene 17.876695378 10545420
MESH:D000236 Adenoma resveratrol 17.8715688382
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 17.1416434500 19061943 17162532 19052882 17620307 18056438
MESH:D018248 Adenoma, Liver Cell Phenobarbital 17.1417620307
MESH:D018248 Adenoma, Liver Cell pirinixic acid 17.1416434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 17.1416835633
MESH:D000310 Adrenal Gland Neoplasms sodium arsenite 3.7315276417
MESH:D018246 Adrenocortical Adenoma Arsenic 10.5817306315
MESH:D018246 Adrenocortical Adenoma sodium arsenite 10.5817306315 16712894
MESH:D000382 Agricultural Workers' Diseases Atrazine 3.3111874814
MESH:D000419 Albuminuria Doxorubicin 8.4321441931
MESH:D000419 Albuminuria Raloxifene 8.4317308373 17451421
MESH:D000437 Alcoholism Mecamylamine 4.8620201817
MESH:D019973 Alcohol-Related Disorders Curcumin 4.1117887948
MESH:D016301 Alveolar Bone Loss Indomethacin 4.4017225004
MESH:D000544 Alzheimer Disease Curcumin 16.7215590663
MESH:D000544 Alzheimer Disease Indomethacin 16.7217627676 15579461
MESH:D000544 Alzheimer Disease Ozone 16.7215513908
MESH:D000544 Alzheimer Disease Plant Extracts 16.7216962711
MESH:D000544 Alzheimer Disease Raloxifene 16.7215800139
MESH:D000544 Alzheimer Disease resveratrol 16.7216183991 16162502
MESH:D000544 Alzheimer Disease rosiglitazone 16.7219621015
MESH:D000544 Alzheimer Disease sulindac sulfide 16.7218759972
MESH:D000690 Amyotrophic Lateral Sclerosis Tetrahydrocannabinol 4.1615204022
MESH:D000707 Anaphylaxis mangiferin 4.5414669257 16536907
MESH:D000740 Anemia Tetrachlorodibenzodioxin 2.1111748828
MESH:D000743 Anemia, Hemolytic Quercetin 3.3717084956
MESH:D000799 Angioedema Acetaminophen 2.8810982225
MESH:D000860 Anoxia Hydrochloric Acid 8.4715090967
MESH:D000860 Anoxia Oxygen 8.4720872349
MESH:D001014 Aortic Aneurysm Indomethacin 3.9310231640
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 8.6119183758
MESH:D017544 Aortic Aneurysm, Abdominal Indomethacin 8.6110388637
MESH:D001145 Arrhythmias, Cardiac Phenylephrine 3.2717460149
MESH:D020261 Arsenic Poisoning Arsenic 2.5018414634 16835338 12569548 16251483
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 7.6211256880
MESH:D001161 Arteriosclerosis tibolone 7.6211256880
MESH:D018771 Arthralgia Indomethacin 4.202160914
MESH:D001169 Arthritis, Experimental Dexamethasone 12.0217659584
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 12.0215885639
MESH:D001169 Arthritis, Experimental Plant Extracts 12.0214686799
MESH:D001169 Arthritis, Experimental resveratrol 12.0217115116
MESH:D001172 Arthritis, Rheumatoid Curcumin 7.6416807698
MESH:D001172 Arthritis, Rheumatoid Indomethacin 7.6411248219
MESH:D001172 Arthritis, Rheumatoid Ozone 7.6415570426
MESH:D001172 Arthritis, Rheumatoid Tobacco Smoke Pollution 7.6419898480
MESH:D001249 Asthma Ozone 2.2716373670 17854713
MESH:D001260 Ataxia Telangiectasia Quercetin 4.0215336622
MESH:D050197 Atherosclerosis Arsenic 24.8812928151 19371607
MESH:D050197 Atherosclerosis Cadmium 24.8815687053
MESH:D050197 Atherosclerosis Curcumin 24.8818704882
MESH:D050197 Atherosclerosis mangiferin 24.8818450471
MESH:D050197 Atherosclerosis Methylcholanthrene 24.8811922910
MESH:D050197 Atherosclerosis Oxygen 24.8816391483
MESH:D050197 Atherosclerosis resveratrol 24.8816873680 17967414
MESH:D050197 Atherosclerosis Tetrahydrocannabinol 24.8815815632
MESH:D001321 Autistic Disorder marker/mechanism 19360663
MESH:D001321 Autistic Disorder Acetaminophen 2.3118445737
MESH:D001321 Autistic Disorder Choline 2.3116818868
MESH:D001321 Autistic Disorder Linoleic Acid 2.3118582451
MESH:D001321 Autistic Disorder Methionine 2.3119267885 16917939 19056591
MESH:D001327 Autoimmune Diseases Cholecalciferol 12.8116142846
MESH:D001327 Autoimmune Diseases Curcumin 12.8119761891
MESH:D001327 Autoimmune Diseases Quercetin 12.8119761891
MESH:D001477 Bartter Syndrome Indomethacin 4.0510684365
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 14.9216206674
MESH:D001778 Blood Coagulation Disorders Hydrochloric Acid 14.9215920416
MESH:D001778 Blood Coagulation Disorders pirinixic acid 14.9219483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 14.9212125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 2.8215340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.0715746008
MESH:D019046 Bone Marrow Neoplasms Doxorubicin 3.7314601052
MESH:D001859 Bone Neoplasms Paclitaxel 3.6815867366
MESH:D001862 Bone Resorption mangiferin 4.059881647
MESH:D001919 Bradycardia Phenylephrine 3.6015306635
MESH:D001929 Brain Edema Indomethacin 4.0611481608
MESH:D020201 Brain Hemorrhage, Traumatic Progesterone 4.3617868700
MESH:D001930 Brain Injuries Progesterone 7.8815665606 15380490 15845082
MESH:D001930 Brain Injuries Raloxifene 7.8816580743
MESH:D002545 Brain Ischemia Curcumin 16.5616770732
MESH:D002545 Brain Ischemia Indomethacin 16.5612524144
MESH:D002545 Brain Ischemia Plant Extracts 16.5616041641
MESH:D002545 Brain Ischemia resveratrol 16.5617600658
MESH:D001932 Brain Neoplasms Curcumin 6.1517596214
MESH:D001932 Brain Neoplasms Doxorubicin 6.1517150277
MESH:D001943 Breast Neoplasms alitretinoin 15.0316344269
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 15.0317474063 20146248
MESH:D001943 Breast Neoplasms Curcumin 15.0319250217 18462866 18593918 16243823
MESH:D001943 Breast Neoplasms decitabine 15.0319208741 18320071
MESH:D001943 Breast Neoplasms Diethylnitrosamine 15.0317474063
MESH:D001943 Breast Neoplasms Doxorubicin 15.0317369602 16595493 18628466 18382427 19526202 17426702 15939500 16115903 17983394 18234424 16264153 16322301 18695136 15136595 16096432 15692762 11325840 15567936 15994142 15993339 16826403 15634643 16935488 15668708
MESH:D001943 Breast Neoplasms Estradiol 15.0317289903 14630087 19861407 17018787 17261762 16675129 18497071 12948864
MESH:D001943 Breast Neoplasms Indomethacin 15.0317401462
MESH:D001943 Breast Neoplasms Methylcholanthrene 15.0317474063
MESH:D001943 Breast Neoplasms Nickel 15.0315986119
MESH:D001943 Breast Neoplasms Oxygen 15.0317263869
MESH:D001943 Breast Neoplasms Paclitaxel 15.0318234424 15136595 11325840 16273361 18223236 18323546 16115903 16244791
MESH:D001943 Breast Neoplasms Progesterone 15.0316175315 15562024 17614352
MESH:D001943 Breast Neoplasms Quercetin 15.0318628248
MESH:D001943 Breast Neoplasms Raloxifene 15.0317261762 15572757 17242785 15775269 16912660 15758505 17595753 17893378 17952589 17440819 16837676 17049068
MESH:D001943 Breast Neoplasms resveratrol 15.0316393696 17651959 17534123
MESH:D001943 Breast Neoplasms Tamoxifen 15.0320005174 19155303 19200415 19221464 19084267 16202921 17049068 19289846 21138602 19189210 17440819 20544844 19103187 19059307 16873071 20065188 17261762 19066611 20859285 17242785 21152245 18821012 20390343 11161223 19288272 18997820 15668708 18815881 19410462 16273361 19487384 17893378 18984771 18351453 19189212 18855134 16818667 19142967 19115204 15565566 19244106 19011961 18425577 18629630 20135344
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 15.0320435547
MESH:D016535 Bronchial Hyperreactivity Hydrochloric Acid 6.3012378975
MESH:D016535 Bronchial Hyperreactivity Ozone 6.3018417511 16777450 18315731 17626835 19059883 15516495 14754758
MESH:D001986 Bronchial Spasm Hydrochloric Acid 4.5015578804
MESH:D002051 Burkitt Lymphoma arsenic trioxide 3.4311589617
MESH:D002056 Burns Indomethacin 3.7710459503
MESH:D002057 Burns, Chemical Plant Extracts 4.379625245
MESH:D002100 Cachexia Indomethacin 9.2415625704 15141370 16537180 11239499
MESH:D002100 Cachexia Ozone 9.2416183385
MESH:D002105 Cadmium Poisoning Quercetin 4.5716962696
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 3.5116111702
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 2.863786805 16011737 16192424 16227642 15721981 15673190 16097048 18705752 16050911 10355542 16124888 15700767
MESH:D002276 Carcinoid Tumor Doxorubicin 9.4816051944
MESH:D002276 Carcinoid Tumor Streptozocin 9.4816051944
MESH:D002277 Carcinoma Curcumin 9.4318593918
MESH:D002277 Carcinoma Methylcholanthrene 9.4310545420
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 9.4316835633
MESH:D002280 Carcinoma, Basal Cell Arsenic 2.9617687452 15504454
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 3.5719066611
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 36.393084413
MESH:D006528 Carcinoma, Hepatocellular Aflatoxin B1 36.3912907637 12619106 21507988
MESH:D006528 Carcinoma, Hepatocellular anthra(1,9-cd)pyrazol-6(2H)-one 36.3919418558
MESH:D006528 Carcinoma, Hepatocellular Arsenic 36.3916507464 17306315
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 36.3914691202 15553829 16217749 11135700 15073043
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 36.3918788625
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 36.3920084675 18788625 3581430 16681979 20935162 17055752 19394651 19052882 19335982 20214788 16830150 18393292 19383236 16328049 19107877 16502159 16779866 18665156 16698587 18971187 19171122 20514400 17978847 10672840 17428255 16878318 19822196 20432363 20007298 10737359 19539802 18691550 11831363 19418558 20101231 16935385 17173139 16569478 3084413 18210153 16540662 19208518 18785209 17761372 21159647 18056438 16288022 20727157 20512989 19919837 16807293 20524982 18978308 17138121 19519916 17162532 18506893 18494052 19701751
MESH:D006528 Carcinoma, Hepatocellular Doxorubicin 36.3918059187 16023760 17876044 16234567
MESH:D006528 Carcinoma, Hepatocellular Estradiol 36.3916924424
MESH:D006528 Carcinoma, Hepatocellular Indomethacin 36.3916391822
MESH:D006528 Carcinoma, Hepatocellular Paclitaxel 36.3916313753
MESH:D006528 Carcinoma, Hepatocellular Phenobarbital 36.3920007298 1701930 6705139 17173139 20935162
MESH:D006528 Carcinoma, Hepatocellular Plant Extracts 36.3918834353
MESH:D006528 Carcinoma, Hepatocellular Quercetin 36.3919519916 12508355
MESH:D006528 Carcinoma, Hepatocellular resveratrol 36.3919321006 16227395
MESH:D006528 Carcinoma, Hepatocellular sodium arsenite 36.3917306315 16507464 15276417
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 36.3916924424
MESH:D018827 Carcinoma, Lewis Lung Indomethacin 8.2711053908
MESH:D018827 Carcinoma, Lewis Lung resveratrol 8.2716675471
MESH:D018276 Carcinoma, Medullary Indomethacin 4.4014736730 18791128 11352223
MESH:D002289 Carcinoma, Non-Small-Cell Lung Curcumin 6.4618414057
MESH:D002289 Carcinoma, Non-Small-Cell Lung sulindac sulfide 6.4612391285
MESH:D002289 Carcinoma, Non-Small-Cell Lung Tobacco Smoke Pollution 6.4611212258
MESH:D021441 Carcinoma, Pancreatic Ductal Quercetin 4.0217234771
MESH:D002291 Carcinoma, Papillary arsenic trioxide 3.9019014326
MESH:D002292 Carcinoma, Renal Cell Doxorubicin 7.6716201981 1485588
MESH:D002292 Carcinoma, Renal Cell Indomethacin 7.6717341418
MESH:D002292 Carcinoma, Renal Cell Vinblastine 7.671485588
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 3.2612490120
MESH:D002294 Carcinoma, Squamous Cell Arsenic 28.7217687452 15504454 18922899
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 28.7220419170
MESH:D002294 Carcinoma, Squamous Cell Curcumin 28.7218462866
MESH:D002294 Carcinoma, Squamous Cell decitabine 28.7219215824
MESH:D002294 Carcinoma, Squamous Cell Doxorubicin 28.726189445
MESH:D002294 Carcinoma, Squamous Cell Indomethacin 28.7215482327 12636206
MESH:D002294 Carcinoma, Squamous Cell Isotretinoin 28.7211237771
MESH:D002294 Carcinoma, Squamous Cell resveratrol 28.7216227395
MESH:D002294 Carcinoma, Squamous Cell sodium arsenite 28.7218572023
MESH:D002294 Carcinoma, Squamous Cell Tetradecanoylphorbol Acetate 28.7218922899
MESH:D002294 Carcinoma, Squamous Cell Tobacco Smoke Pollution 28.7211212258
MESH:D002295 Carcinoma, Transitional Cell Arsenic 11.0118640142
MESH:D002295 Carcinoma, Transitional Cell Raloxifene 11.0117572228
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 11.0117572228
MESH:D006332 Cardiomegaly Phenylephrine 14.8011754973 15728586 17124262 16170337 11179087 17287366
MESH:D006332 Cardiomegaly Plant Extracts 14.8017645561
MESH:D006332 Cardiomegaly Quercetin 14.8019794523
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 14.8018670907 18850075 16120746
MESH:D006332 Cardiomegaly valsartan 14.8019597038
MESH:D009202 Cardiomyopathies Doxorubicin 9.2615505089 17007740 17974986 16364871 17382496 17351982 16269455 16731534 16278810 16651473 17924179 16612575 16952015 17131338 16455267 17308081 17928571 17329180 16109756 17519947 15792986 18627295 16242529 15476868 15811867
MESH:D009202 Cardiomyopathies pimagedine 9.2616612575
MESH:D009202 Cardiomyopathies valsartan 9.2616247790
MESH:D002311 Cardiomyopathy, Dilated Doxorubicin 2.5116243910 17334414
MESH:D002318 Cardiovascular Diseases Arsenic 11.4519152805 15738583 17938729
MESH:D002318 Cardiovascular Diseases Raloxifene 11.4515775269
MESH:D002318 Cardiovascular Diseases resveratrol 11.4515458977
MESH:D002318 Cardiovascular Diseases valsartan 11.4511230374
MESH:D002340 Carotid Artery Diseases Arsenic 3.4716973168 18022660
MESH:D020212 Carotid Artery Injuries bivalirudin 5.6411316950
MESH:D002375 Catalepsy Tetrahydrocannabinol 4.7810318961
MESH:D002386 Cataract Acetaminophen 8.9210977129
MESH:D002386 Cataract pimagedine 8.9217936468 15003327
MESH:D002386 Cataract Simvastatin 8.9212518039
MESH:D002471 Cell Transformation, Neoplastic Cadmium 28.7817332340
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 28.7812371664
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 28.7821159647 7505956 2727394 17174075
MESH:D002471 Cell Transformation, Neoplastic Estradiol 28.7818566989
MESH:D002471 Cell Transformation, Neoplastic Galactosamine 28.787505956
MESH:D002471 Cell Transformation, Neoplastic Methylcholanthrene 28.7816192471
MESH:D002471 Cell Transformation, Neoplastic Methylnitronitrosoguanidine 28.782727394
MESH:D002471 Cell Transformation, Neoplastic monomethylarsonous acid 28.7819716837
MESH:D002471 Cell Transformation, Neoplastic sodium arsenite 28.7820056578 19524636
MESH:D002493 Central Nervous System Diseases Phenobarbital 3.324080065
MESH:D002659 Child Development Disorders, Pervasive Methionine 3.8719267885
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 6.5519052882
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 6.5516835633
MESH:D002764 Cholecystitis Indomethacin 4.2011181007
MESH:D002779 Cholestasis Cyclosporine 13.0719486331
MESH:D002779 Cholestasis Ethinyl Estradiol 13.0716105132 17681005 17110522 11677210 15861022 17333356 16919318
MESH:D002779 Cholestasis Levonorgestrel 13.0715861022
MESH:D002779 Cholestasis pirinixic acid 13.0719176532
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 1.618697196 15668235 16354765 12621046 15340226
MESH:D003072 Cognition Disorders Raloxifene 3.6915800139
MESH:D003092 Colitis Curcumin 6.7318200517 16782535 16804969
MESH:D003092 Colitis resveratrol 6.7316474422
MESH:D003103 Coloboma Curcumin 3.6718809619
MESH:D003110 Colonic Neoplasms arsenite 12.4815037631
MESH:D003110 Colonic Neoplasms Curcumin 12.4816340194 19359593
MESH:D003110 Colonic Neoplasms decitabine 12.4817616700
MESH:D003110 Colonic Neoplasms Dexamethasone 12.4815824018
MESH:D003110 Colonic Neoplasms Indomethacin 12.4811260862 15625704 15637740 15963497 15786552 15936596
MESH:D003110 Colonic Neoplasms Quercetin 12.4817148506 17191121 19440933 19056647 15741050 16640504 11134977
MESH:D003110 Colonic Neoplasms resveratrol 12.4816338953
MESH:D015179 Colorectal Neoplasms arsenic trioxide 9.4820501625
MESH:D015179 Colorectal Neoplasms decitabine 9.4818981723
MESH:D015179 Colorectal Neoplasms Doxorubicin 9.4818259882 18802399
MESH:D015179 Colorectal Neoplasms Indomethacin 9.4812606626 17054584 11197048 18059344
MESH:D015179 Colorectal Neoplasms Paclitaxel 9.4818802399
MESH:D015179 Colorectal Neoplasms Quercetin 9.4818852136 18095365
MESH:D015179 Colorectal Neoplasms resveratrol 9.4816550006
MESH:D015179 Colorectal Neoplasms Vinblastine 9.4818802399
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 2.2314669216 17141729
MESH:D016510 Corneal Neovascularization Curcumin 3.9618497527
MESH:D003324 Coronary Artery Disease valsartan 3.4517719468
MESH:D003327 Coronary Disease Fructose 6.4618504504
MESH:D003327 Coronary Disease resveratrol 6.4616507316
MESH:D023903 Coronary Restenosis arsenic trioxide 3.2712609071
MESH:D003328 Coronary Thrombosis bivalirudin 4.8518036681
MESH:D018352 Coronavirus Infections Indomethacin 4.7417302372
MESH:D003384 Coxsackievirus Infections valsartan 4.8920392896
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 3.9210525206
MESH:D019465 Craniofacial Abnormalities Dexamethasone 3.9217728286
MESH:D019465 Craniofacial Abnormalities Isotretinoin 3.9218769834 9879862
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 3.9215322242 10048152 20055451
MESH:D003457 Cryptosporidiosis mangiferin 4.8916547730
MESH:D003550 Cystic Fibrosis Simvastatin 4.1119747007
MESH:D003556 Cystitis Hydrochloric Acid 4.5012599022 19279288 20719367 12853844
MESH:D018856 Cystitis, Interstitial Hydrochloric Acid 4.8417714534
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 3.2015213294
MESH:D003711 Demyelinating Diseases Tamoxifen 3.4319031437
MESH:D003865 Depressive Disorder, Major Raloxifene 3.3317474826
MESH:D017449 Dermatitis, Allergic Contact Dexamethasone 12.2612438553
MESH:D017449 Dermatitis, Allergic Contact Nickel 12.2617100760 17244072 19470301
MESH:D017449 Dermatitis, Allergic Contact nickel sulfate 12.2611298694 16823706 16780908
MESH:D017449 Dermatitis, Allergic Contact Thimerosal 12.2616958921 15932584
MESH:D017449 Dermatitis, Allergic Contact Trientine 12.268970840
MESH:D003876 Dermatitis, Atopic pirinixic acid 1.8818249437
MESH:D003877 Dermatitis, Contact Nickel 3.762952479
MESH:D002658 Developmental Disabilities Choline 6.6716818868
MESH:D002658 Developmental Disabilities Thimerosal 6.6715764492
MESH:D048909 Diabetes Complications bivalirudin 5.3918436116
MESH:D003920 Diabetes Mellitus rosiglitazone 11.0717446233
MESH:D003920 Diabetes Mellitus Streptozocin 11.0716285004
MESH:D003920 Diabetes Mellitus Trientine 11.0716973718
MESH:D003921 Diabetes Mellitus, Experimental Fructose 21.9018603373
MESH:D003921 Diabetes Mellitus, Experimental mangiferin 21.9012093613 19028559
MESH:D003921 Diabetes Mellitus, Experimental Quercetin 21.9019496084
MESH:D003921 Diabetes Mellitus, Experimental resveratrol 21.9016873680
MESH:D003921 Diabetes Mellitus, Experimental Streptozocin 21.908740154 19496084 19960420 2177838 16684804 15831366 15862027 18715473 16286809 12446591 7637645 11055810 19298542 19586609 6379147 12083368 15298345 11260395 17442507 18603373 12644472 1374869 17874149 12093613
MESH:D003921 Diabetes Mellitus, Experimental valsartan 21.9011508273
MESH:D003922 Diabetes Mellitus, Type 1 Streptozocin 3.2418603373
MESH:D003924 Diabetes Mellitus, Type 2 Curcumin 15.2318403477
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 15.2320387270
MESH:D003924 Diabetes Mellitus, Type 2 Fructose 15.2318603373
MESH:D003924 Diabetes Mellitus, Type 2 mangiferin 15.239881663 11315760
MESH:D003924 Diabetes Mellitus, Type 2 rosiglitazone 15.2312642470
MESH:D003924 Diabetes Mellitus, Type 2 Streptozocin 15.2319586609 19647726
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 15.2317107852
MESH:D058065 Diabetic Cardiomyopathies Streptozocin 4.7716025228
MESH:D003928 Diabetic Nephropathies Curcumin 40.4118204486
MESH:D003928 Diabetic Nephropathies Estradiol 40.4119279558
MESH:D003928 Diabetic Nephropathies mangiferin 40.4119960420 19706694
MESH:D003928 Diabetic Nephropathies Plant Extracts 40.4119706694
MESH:D003928 Diabetic Nephropathies Raloxifene 40.4115920148 17308373 17451421
MESH:D003928 Diabetic Nephropathies resveratrol 40.4116286809
MESH:D003928 Diabetic Nephropathies Streptozocin 40.4119960420 19682444
MESH:D003928 Diabetic Nephropathies Tamoxifen 40.4119279558
MESH:D003928 Diabetic Nephropathies valsartan 40.4111427623 18630688
MESH:D003929 Diabetic Neuropathies Progesterone 3.5617187935
MESH:D003930 Diabetic Retinopathy Streptozocin 4.5117662242
MESH:D003967 Diarrhea Dexamethasone 5.327237001
MESH:D003967 Diarrhea Indomethacin 5.327907874 7237001
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 12.2119923254 12540782 16177239 14725611 19085960 16393943 15968718 16781746 14986274 11739529 2444490 11529661 12594235 19416960 12958197 12153990 16227642 11743745 17906064 10663392 15619225 12392966 12705907 19370779 19164858 14550746 16109766 18713872 11287661 17562736 18071297 19739265 11421492 11461765 10915739 16485898 19420014 10774834 11834606 16081117 17522070
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 12.213732212 10092053 7120509 4309450 15998439 17522070 6623471 10915739 11566570 15027814 15968718 19085960 19336974 6884620 9327722 21278145 3786805 2869522 7179309 16227642 16177239 7440962
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 12.2119107877
MESH:D056486 Drug-Induced Liver Injury Diquat 12.2118164269 18445702
MESH:D056486 Drug-Induced Liver Injury Doxorubicin 12.2117416283
MESH:D056486 Drug-Induced Liver Injury Galactosamine 12.2115968718
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 12.2120420201
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 3.1319426721
MESH:D004362 Drug Toxicity Doxorubicin 5.5818602426
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 5.5811462148
MESH:D004374 Ductus Arteriosus, Patent Indomethacin 4.1918446180 12774134 16133044 17190690 18043480 16326151
MESH:D004381 Duodenal Ulcer Curcumin 6.4217351913
MESH:D004381 Duodenal Ulcer Indomethacin 6.4211991626 11595415 16699067 17202747 11535926 17045617 17151854 17351913 17329845 11595431 10671773
MESH:D050171 Dyslipidemias Fenofibrate 3.6816707586
MESH:D004417 Dyspnea Chlorine 7.4920016425
MESH:D004417 Dyspnea Oxygen 7.4920016425
MESH:D004421 Dystonia Phenobarbital 3.111851702
MESH:D004485 Eczema Dexamethasone 3.5512438553
MESH:D004487 Edema Dexamethasone 31.2519703484
MESH:D004487 Edema Indomethacin 31.258273558 16100529 10653021 7907874 19703484 8985016 7990266
MESH:D004487 Edema perfluorooctanoic acid 31.2517259670 12083418
MESH:D004487 Edema pirinixic acid 31.2512083418
MESH:D004487 Edema Plant Extracts 31.2512787963
MESH:D004487 Edema Raloxifene 31.2515860553
MESH:D004487 Edema resveratrol 31.258985016
MESH:D004487 Edema rosiglitazone 31.2512083418
MESH:D004487 Edema Tetrachlorodibenzodioxin 31.2511000095 12711302
MESH:D004487 Edema Tetradecanoylphorbol Acetate 31.259599246 16716910 8273558 11698051 15177302 7812673 8113982
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 2.9316714409 15322242 18230668
MESH:D016769 Embolism and Thrombosis bivalirudin 5.0016084352
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 19.2112538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Progesterone 19.2117692515
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Raloxifene 19.2115845917
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental resveratrol 19.2117872969
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 19.2119031437
MESH:D004701 Endocrine Gland Neoplasms decitabine 4.1419294695
MESH:D016889 Endometrial Neoplasms Doxorubicin 12.0717359293
MESH:D016889 Endometrial Neoplasms Estradiol 12.0718566989 19148513 11473722
MESH:D016889 Endometrial Neoplasms Fenofibrate 12.0716569247
MESH:D016889 Endometrial Neoplasms Tamoxifen 12.0719155303 20544844 16202921 17893378
MESH:D004715 Endometriosis Indomethacin 14.9315652904
MESH:D004715 Endometriosis Mifepristone 14.9316134523
MESH:D004715 Endometriosis Progesterone 14.9316134523
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 14.9310568697 9294722
MESH:D004719 Endomyocardial Fibrosis Doxorubicin 10.8418037988
MESH:D004719 Endomyocardial Fibrosis Plant Extracts 10.8415268973
MESH:D019446 Endotoxemia Indomethacin 7.5118509659
MESH:D019446 Endotoxemia Lipopolysaccharides 7.5115328337 15821434 17637181
MESH:D004751 Enteritis Indomethacin 3.7810567023 17763956 16328016
MESH:D020345 Enterocolitis, Necrotizing Indomethacin 9.2717980183
MESH:D020345 Enterocolitis, Necrotizing resveratrol 9.2717923197
MESH:D004802 Eosinophilia Indomethacin 3.1511298111
MESH:D004831 Epilepsies, Myoclonic Phenobarbital 3.183659116
MESH:D004828 Epilepsies, Partial Phenobarbital 2.9211558140 3922381
MESH:D004827 Epilepsy Epinephrine 10.96821787
MESH:D004827 Epilepsy Phenobarbital 10.9620417680
MESH:D004827 Epilepsy Plant Extracts 10.9619700373 19439326
MESH:D004827 Epilepsy Tetrahydrocannabinol 10.96821787
MESH:D004832 Epilepsy, Absence Phenobarbital 2.726401628
MESH:D017029 Epilepsy, Complex Partial Phenobarbital 3.327750514
MESH:D004830 Epilepsy, Tonic-Clonic Phenobarbital 3.073659116
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 4.1416302075
MESH:D004935 Esophageal Diseases Hydrochloric Acid 4.8419566590
MESH:D004938 Esophageal Neoplasms arsenic trioxide 7.2812903497
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 7.2816530937
MESH:D004938 Esophageal Neoplasms Indomethacin 7.2811005569
MESH:D004938 Esophageal Neoplasms Paclitaxel 7.2816481741
MESH:D004941 Esophagitis Hydrochloric Acid 5.0412928072
MESH:D004942 Esophagitis, Peptic Hydrochloric Acid 5.0414621274 20516732 11346197
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 2.2511564622
MESH:D005234 Fatty Liver marker/mechanism 18641190
MESH:D005234 Fatty Liver arsenic trioxide 57.7615073043
MESH:D005234 Fatty Liver arsenite 57.7618296743
MESH:D005234 Fatty Liver Carbon Tetrachloride 57.7612795759 16239168 12631006 15959796 19224547 17595544 61145 16045604
MESH:D005234 Fatty Liver Curcumin 57.7619297423
MESH:D005234 Fatty Liver Cyclosporine 57.7619224547
MESH:D005234 Fatty Liver Diethylnitrosamine 57.7620387270 21071580
MESH:D005234 Fatty Liver Ethinyl Estradiol 57.7615345470
MESH:D005234 Fatty Liver Fructose 57.7619196556 18395287 18641190
MESH:D005234 Fatty Liver mangiferin 57.7615975614
MESH:D005234 Fatty Liver pirinixic acid 57.7620131406 19236843
MESH:D005234 Fatty Liver Plant Extracts 57.7615975614
MESH:D005234 Fatty Liver Raloxifene 57.7617473493
MESH:D005234 Fatty Liver rosiglitazone 57.7619196556
MESH:D005234 Fatty Liver Tamoxifen 57.7614986274 19224547
MESH:D052776 Female Urogenital Diseases Tamoxifen 2.5716709447
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 2.5311858732
MESH:D005334 Fever Indomethacin 6.5411852909 10431976 17627676
MESH:D005334 Fever Lipopolysaccharides 6.5411852909 9205823
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 3.5714745880
MESH:D018222 Fibromatosis, Aggressive Doxorubicin 8.2919069698
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 8.2919069698
MESH:D005354 Fibrosarcoma Indomethacin 8.9410962813
MESH:D005354 Fibrosarcoma Methylcholanthrene 8.9414633661 10962813
MESH:D005355 Fibrosis arsenite 43.0718296743
MESH:D005355 Fibrosis Carbon Tetrachloride 43.0718705752
MESH:D005355 Fibrosis Curcumin 43.0718705752
MESH:D005355 Fibrosis Cyclosporine 43.0712168785 12639820
MESH:D005355 Fibrosis Fructose 43.0718504504
MESH:D005355 Fibrosis Hydrochloric Acid 43.0718497604
MESH:D005355 Fibrosis Indomethacin 43.0717994277
MESH:D005355 Fibrosis Quercetin 43.0719474275
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 43.0720067830
MESH:D005355 Fibrosis valsartan 43.0716893502
MESH:D005499 Folliculitis Indomethacin 4.2011298111
MESH:D005534 Foot Diseases Arsenic 4.596392382
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 3.3516904648
MESH:D005739 Gas Poisoning Chlorine 14.3320016425
MESH:D005739 Gas Poisoning Hydrochloric Acid 14.3312378975
MESH:D005739 Gas Poisoning Oxygen 14.3320016425
MESH:D005756 Gastritis Acetaminophen 13.6116983495
MESH:D005756 Gastritis Diquat 13.6115046732
MESH:D005756 Gastritis Indomethacin 13.6115046732
MESH:D005764 Gastroesophageal Reflux Hydrochloric Acid 4.4120616304 20516732 20545468 19951613 12212954 19957777
MESH:D005770 Gastrointestinal Neoplasms Curcumin 3.7618462866
MESH:D005833 Genital Neoplasms, Female sodium arsenite 3.7216452187
MESH:D005885 Gingival Hyperplasia Cyclosporine 3.268708960
MESH:D005909 Glioblastoma Curcumin 11.2717596214
MESH:D005909 Glioblastoma Doxorubicin 11.2717150277
MESH:D005909 Glioblastoma Indomethacin 11.2712870263
MESH:D005909 Glioblastoma Quercetin 11.2719804834
MESH:D005910 Glioma Indomethacin 4.6318371953 16487511
MESH:D005910 Glioma Quercetin 4.6317643826
MESH:D015432 Glomerulonephritis, Membranoproliferative valsartan 4.6316928621
MESH:D005923 Glomerulosclerosis, Focal Segmental Indomethacin 3.4811849393
MESH:D018149 Glucose Intolerance Fructose 4.4319165636
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 3.6210696789
MESH:D006073 Gout Indomethacin 4.4011248219
MESH:D006258 Head and Neck Neoplasms Curcumin 12.6218462866 18829502
MESH:D006258 Head and Neck Neoplasms decitabine 12.6219215824
MESH:D006258 Head and Neck Neoplasms Doxorubicin 12.6215692506
MESH:D006258 Head and Neck Neoplasms Indomethacin 12.6215482327
MESH:D006356 Heartburn Hydrochloric Acid 4.8419566590
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 4.4120471113
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 4.4110048152 11294989
MESH:D006331 Heart Diseases Doxorubicin 12.2216244371 16495754 18006777 16330681 17875725 16244372 17888722 16707910 16879835 16144979 14766674 18674790 12587719
MESH:D006331 Heart Diseases mangiferin 12.2212093613
MESH:D006331 Heart Diseases Raloxifene 12.2211110106
MESH:D006331 Heart Diseases Streptozocin 12.2212093613
MESH:D006333 Heart Failure Doxorubicin 11.4117481944
MESH:D006333 Heart Failure pirinixic acid 11.4120558911
MESH:D006333 Heart Failure Plant Extracts 11.4118097624
MESH:D006333 Heart Failure valsartan 11.4119027736
MESH:D006394 Hemangiosarcoma Doxorubicin 3.0415692506
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 3.4715720958
MESH:D006463 Hemolytic-Uremic Syndrome Lipopolysaccharides 3.5316366002
MESH:D006470 Hemorrhage bivalirudin 7.7719147609 16598112 18436116 19281522 19360860 16125490
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 7.7711000095
MESH:D006501 Hepatic Encephalopathy Indomethacin 3.7015633222
MESH:D006505 Hepatitis Carbon Tetrachloride 2.7019900420 19110552
MESH:D019698 Hepatitis C, Chronic Indomethacin 3.7715135802
MESH:D006527 Hepatolenticular Degeneration Trientine 5.3817276780
MESH:D006529 Hepatomegaly perfluorooctanoic acid 13.173609246
MESH:D006529 Hepatomegaly Phenobarbital 13.1716109766
MESH:D006529 Hepatomegaly pirinixic acid 13.1718467677 19176532 16221962 19772884
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 13.1715340226 16120746 12621046
MESH:D015417 Hereditary Sensory and Motor Neuropathy Curcumin 4.1017701891
MESH:D006548 Hernia, Diaphragmatic Dexamethasone 2.637520565
MESH:D006558 Herpes Genitalis Estradiol 4.0615709030
MESH:D006561 Herpes Simplex mangiferin 11.1810715843
MESH:D006561 Herpes Simplex Plant Extracts 11.1810715843
MESH:D006561 Herpes Simplex resveratrol 11.1816876885
MESH:D015658 HIV Infections Nickel 5.1417263646
MESH:D015658 HIV Infections Plant Extracts 5.1412878215
MESH:D006689 Hodgkin Disease Doxorubicin 7.6715147373 17606976 18501091
MESH:D006689 Hodgkin Disease sodium arsenite 7.6712676792
MESH:D006689 Hodgkin Disease Vinblastine 7.6718180244 18501091
MESH:D019584 Hot Flashes Estradiol 11.9017088409
MESH:D019584 Hot Flashes Plant Extracts 11.9014716179 16566672 17454163
MESH:D019584 Hot Flashes Progestins 11.9014716179
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.0816959395 8697196 18606429 15340226 16354765
MESH:D006930 Hyperalgesia Acetaminophen 16.2316870215
MESH:D006930 Hyperalgesia Guanethidine 16.2312727271
MESH:D006930 Hyperalgesia Indomethacin 16.2312727271
MESH:D006930 Hyperalgesia perfluorooctanoic acid 16.2312083418
MESH:D006930 Hyperalgesia rosiglitazone 16.2312083418
MESH:D034321 Hyperamylasemia Indomethacin 4.7417883296
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 3.5816899240
MESH:D006937 Hypercholesterolemia Curcumin 6.5118704882
MESH:D006937 Hypercholesterolemia resveratrol 6.5117188708
MESH:D006940 Hyperemia Hydrochloric Acid 9.5712646421
MESH:D006940 Hyperemia Indomethacin 9.5712524144
MESH:D006943 Hyperglycemia pirinixic acid 6.4220558911
MESH:D006943 Hyperglycemia Quercetin 6.4218262572 11834736
MESH:D020138 Hyperhomocysteinemia Catechin 7.1617292331
MESH:D020138 Hyperhomocysteinemia Plant Extracts 7.1616484555
MESH:D006946 Hyperinsulinism Fructose 7.7814757778 18563319 19008412 15752949 18360027
MESH:D006946 Hyperinsulinism mangiferin 7.789881663 11315760
MESH:D017488 Hyperkeratosis, Epidermolytic Arsenic 3.6017050553
MESH:D006949 Hyperlipidemias Fructose 19.5215752949
MESH:D006949 Hyperlipidemias Indomethacin 19.5217546600
MESH:D006949 Hyperlipidemias mangiferin 19.5215975614
MESH:D006949 Hyperlipidemias Plant Extracts 19.5215268973 15975614
MESH:D006949 Hyperlipidemias resveratrol 19.5216873680
MESH:D006938 Hyperlipoproteinemia Type II Simvastatin 4.4216238680
MESH:D006967 Hypersensitivity Butylated Hydroxytoluene 6.6417604070
MESH:D006967 Hypersensitivity mangiferin 6.6416536907
MESH:D006973 Hypertension Arsenic 27.9316076760 9931084 11953799
MESH:D006973 Hypertension Cyclosporine 27.9310903974
MESH:D006973 Hypertension Dexamethasone 27.9317042910
MESH:D006973 Hypertension Fructose 27.9314568997 16843071 14573337 14633139 19008412
MESH:D006973 Hypertension Phenylephrine 27.9312717712 8949925
MESH:D006973 Hypertension Quercetin 27.9318356687
MESH:D006973 Hypertension Raloxifene 27.9315787275 17577099
MESH:D006973 Hypertension telmisartan 27.9316077267
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 27.9318850075 18670907
MESH:D006973 Hypertension valsartan 27.9311427623 12692753 16475468 10903974 18390891 12850387 20102058 18344623
MESH:D006974 Hypertension, Malignant valsartan 5.4411560862
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 8.3215338365
MESH:D006975 Hypertension, Portal Hydrochloric Acid 8.3216984587
MESH:D006976 Hypertension, Pulmonary Hydrochloric Acid 3.7219262391
MESH:D015228 Hypertriglyceridemia Fructose 4.2219342510 19799862
MESH:D006984 Hypertrophy Phenylephrine 3.6818502941 12791704
MESH:D017379 Hypertrophy, Left Ventricular resveratrol 3.4517488730
MESH:D006987 Hypesthesia Arsenic 4.5916093927
MESH:D007021 Hypospadias Ethinyl Estradiol 2.8816945680 16569931
MESH:D007022 Hypotension Epinephrine 7.126740701
MESH:D007022 Hypotension Hydrochloric Acid 7.1211574821
MESH:D007035 Hypothermia Tetrahydrocannabinol 5.0010318961
MESH:D007077 Ileal Diseases 1-Methyl-3-isobutylxanthine 9.5018306037
MESH:D007077 Ileal Diseases Indomethacin 9.5018306037 10574470
MESH:D007079 Ileitis Indomethacin 4.4016133968 10651667 10647630
MESH:D007154 Immune System Diseases mangiferin 4.8916076520
MESH:D007235 Infant, Premature, Diseases Indomethacin 4.4016133044
MESH:D020244 Infarction, Middle Cerebral Artery Progesterone 8.3915869954
MESH:D020244 Infarction, Middle Cerebral Artery resveratrol 8.3917600658
MESH:D007247 Infertility, Female Ethinyl Estradiol 2.5712013081
MESH:D007248 Infertility, Male Atrazine 13.6612948887
MESH:D007248 Infertility, Male decitabine 13.6617581917
MESH:D007248 Infertility, Male Diquat 13.664850670
MESH:D007248 Infertility, Male Ethinyl Estradiol 13.6617937319
MESH:D007248 Infertility, Male sodium arsenite 13.6615346721 12646999
MESH:D007249 Inflammation bivalirudin 54.0316125490
MESH:D007249 Inflammation Curcumin 54.0317151092 18403477 16956363
MESH:D007249 Inflammation Dexamethasone 54.038960868 11099482
MESH:D007249 Inflammation Diethylnitrosamine 54.0318785209
MESH:D007249 Inflammation Hydrochloric Acid 54.0311574821
MESH:D007249 Inflammation Indomethacin 54.037812673 12568917 3291741
MESH:D007249 Inflammation Lipopolysaccharides 54.0312878042 9205823 17255318 17963957 17237260
MESH:D007249 Inflammation mangiferin 54.0315222974
MESH:D007249 Inflammation Nickel 54.0316166738
MESH:D007249 Inflammation perfluorooctanoic acid 54.0312083418
MESH:D007249 Inflammation Plant Extracts 54.0316366677 19332304 12787963 15997105
MESH:D007249 Inflammation Progesterone 54.0315869954
MESH:D007249 Inflammation resveratrol 54.0316366677
MESH:D007249 Inflammation rosiglitazone 54.0312083418
MESH:D007249 Inflammation Tamoxifen 54.0319457130
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 54.0312200463 12878042
MESH:D007249 Inflammation Tetradecanoylphorbol Acetate 54.0315177302 11698051 8273558 7562506 7812673
MESH:D007249 Inflammation Tobacco Smoke Pollution 54.0318590791
MESH:D015212 Inflammatory Bowel Diseases Curcumin 2.7218596194 18200517
MESH:D007251 Influenza, Human Quercetin 7.9916624496
MESH:D007251 Influenza, Human resveratrol 7.9916624496
MESH:D007333 Insulin Resistance Estradiol 15.8216627594 16393666
MESH:D007333 Insulin Resistance Fructose 15.8214757778 19586609 19799862 18981581 19342510 19008412 18057795 14573337 17133782 18563319 14633139
MESH:D007333 Insulin Resistance mangiferin 15.8211315760
MESH:D007333 Insulin Resistance pirinixic acid 15.8216306350
MESH:D007333 Insulin Resistance rosiglitazone 15.8216306350
MESH:D007410 Intestinal Diseases Hydrochloric Acid 11.4711574821
MESH:D007410 Intestinal Diseases Indomethacin 11.4715831440 11713966 11686837 17329856 11855677 10210152 17994277 18236018 15610444
MESH:D007410 Intestinal Diseases pimagedine 11.4711713966
MESH:D007414 Intestinal Neoplasms Curcumin 7.2810783313
MESH:D007414 Intestinal Neoplasms Plant Extracts 7.2812584176 12351151 12628509
MESH:D019586 Intracranial Hypertension Indomethacin 4.4015241188
MESH:D019189 Iron Metabolism Disorders Lipopolysaccharides 3.7317255318
MESH:D007511 Ischemia bivalirudin 8.6618436116
MESH:D007511 Ischemia mangiferin 8.6616806951
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 2.4616580747
MESH:D007579 Jejunal Diseases 1-Methyl-3-isobutylxanthine 9.5018306037
MESH:D007579 Jejunal Diseases Indomethacin 9.5010574470 18306037 16133968
MESH:D007627 Keloid Quercetin 4.0217086741
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 3.4715604871
MESH:D007642 Keratosis Arsenic 4.0416930632 12749816
MESH:D017492 Keratosis, Seborrheic alitretinoin 4.6816144296
MESH:D007674 Kidney Diseases Acetaminophen 34.3312587719 15629191
MESH:D007674 Kidney Diseases Cadmium 34.3316962696 16322080 16226777
MESH:D007674 Kidney Diseases Cyclosporine 34.3318776723 8314463 10903974
MESH:D007674 Kidney Diseases Doxorubicin 34.3315369732 15699352 16775033
MESH:D007674 Kidney Diseases Estradiol 34.3315618244
MESH:D007674 Kidney Diseases Indomethacin 34.3317190690
MESH:D007674 Kidney Diseases mangiferin 34.3312093613
MESH:D007674 Kidney Diseases Quercetin 34.3316962696
MESH:D007674 Kidney Diseases sodium arsenite 34.3320008137
MESH:D007674 Kidney Diseases Streptozocin 34.3312093613
MESH:D007674 Kidney Diseases valsartan 34.3312164870 10903974 16893502
MESH:D007676 Kidney Failure, Chronic Doxorubicin 3.2816707910
MESH:D007680 Kidney Neoplasms Cyclosporine 7.7312371664
MESH:D007680 Kidney Neoplasms Estradiol 7.7315610895
MESH:D007680 Kidney Neoplasms Tamoxifen 7.7318625569
MESH:D007818 Laryngeal Diseases Hydrochloric Acid 5.3916498863
MESH:D007826 Laryngismus Hydrochloric Acid 5.3911510729
MESH:D007859 Learning Disorders mangiferin 4.0319182383
MESH:D007889 Leiomyoma Curcumin 8.1918555241
MESH:D007889 Leiomyoma Raloxifene 8.1916973256
MESH:D016773 Leishmaniasis, Cutaneous Indomethacin 3.1110320625 11703811 12228301
MESH:D007938 Leukemia arsenic trioxide 10.1415070760
MESH:D007938 Leukemia Curcumin 10.1418462866
MESH:D007938 Leukemia decitabine 10.1419235587 18980019
MESH:D007938 Leukemia Quercetin 10.1417468513
MESH:D004915 Leukemia, Erythroblastic, Acute Doxorubicin 4.1816085563
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 6.8717077332 12560223
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell Curcumin 6.8716106398
MESH:D007948 Leukemia, Monocytic, Acute anthra(1,9-cd)pyrazol-6(2H)-one 14.2216972261
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 14.2216972261
MESH:D007948 Leukemia, Monocytic, Acute U 0126 14.2216972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 9.8114633726
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive Indomethacin 9.8110785260 15631656 16572323
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive mangiferin 9.8115498116
MESH:D007951 Leukemia, Myeloid arsenic trioxide 6.7019077051
MESH:D007951 Leukemia, Myeloid decitabine 6.7017236224 18454857 19117987
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 4.4916467208 20471514 16968895 17050201 19850784
MESH:D015470 Leukemia, Myeloid, Acute decitabine 4.4919387464 18704418 18206229 17679729 18460780 19010910
MESH:D015470 Leukemia, Myeloid, Acute Indomethacin 4.4918360721
MESH:D015477 Leukemia, Myelomonocytic, Chronic decitabine 4.4918055864
MESH:D015473 Leukemia, Promyelocytic, Acute Arsenic 8.7517339181
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 8.7517869043 19642359 15213294 9834237 15622746 19035177 11161223 16823087 15336539 11468182 19075265 17107899 16966277 16112521 12679006 17649720 19225113 12712474 16330433 17217047 16891316 17712046 15748426 12018890 16331271
MESH:D015473 Leukemia, Promyelocytic, Acute resveratrol 8.7516087638
MESH:D015458 Leukemia, T-Cell arsenic trioxide 8.6816882451
MESH:D015458 Leukemia, T-Cell Curcumin 8.6816106398
MESH:D007964 Leukocytosis Indomethacin 4.4016537180
MESH:D007969 Leukomalacia, Periventricular Indomethacin 4.7417980183
MESH:D007970 Leukopenia Lipopolysaccharides 3.7515821434
MESH:D007984 Leydig Cell Tumor perfluorooctanoic acid 4.278812269
MESH:D008064 Lipidoses Tamoxifen 2.4217567588 15342952
MESH:D008080 Liposarcoma Paclitaxel 3.9317353645
MESH:D008101 Liver Abscess, Amebic Indomethacin 4.7411479899
MESH:D008103 Liver Cirrhosis arsenite 17.7918296743
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 17.7916221502 17157831 21278145 11903743 17174718 16943688 17334410 11408273 16239168
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 17.7918522880 19638242 18407596 20032147 18665156
MESH:D008103 Liver Cirrhosis Hydrochloric Acid 17.7916984587
MESH:D008103 Liver Cirrhosis Phenobarbital 17.7921047994
MESH:D008103 Liver Cirrhosis Plant Extracts 17.7917157831
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 29.8417631135 15931870 17714472 17565644 12546737 12609069 14620537 18279442 15818738 18395095 12632514 12445418 15338365 16027843 15730626 15893842 12667390 17721639 17640975 15959796 18054572 15650968 15673190 14716833 16192424 17900296 18376398 14724832 17708605 15052691 18187930 12586293 18210741 18429990 17823541 16638106 12666154 16136751 17525996 15123356 17698563 16097048 17766677 12649538 12389079 18263696 15876570 17976157 18156304 18277467 18395914 10355542 17557913 17869086 15370692 18339082 18251166 12741479 18412020 18166357 12445421 15362042 13678700 18481824 14716496 16011737 17805973 18472332 18006644 14748882 16248980 18420326 12632512 17481882 15925388 16015684 17761835 11481614 18418968 16033810 12898905 17944888 14512876 18317297 20821823 18205269 16116963 12958196 18472094 15057751 18705752 17922224 15996030
MESH:D008106 Liver Cirrhosis, Experimental Curcumin 29.8417355460 18705752 18006644
MESH:D008106 Liver Cirrhosis, Experimental Dexamethasone 29.8416718785
MESH:D008106 Liver Cirrhosis, Experimental Doxorubicin 29.8416439617 16595196
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 29.8414716833 14659978
MESH:D008106 Liver Cirrhosis, Experimental Fenofibrate 29.8415474484
MESH:D008106 Liver Cirrhosis, Experimental Indomethacin 29.8418194892
MESH:D008106 Liver Cirrhosis, Experimental Lipopolysaccharides 29.8412878042
MESH:D008106 Liver Cirrhosis, Experimental Methionine 29.8415158331
MESH:D008106 Liver Cirrhosis, Experimental pirfenidone 29.8412445421 15571005
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 29.8415474484
MESH:D008106 Liver Cirrhosis, Experimental Plant Extracts 29.8415479170
MESH:D008106 Liver Cirrhosis, Experimental Quercetin 29.8412741479
MESH:D008106 Liver Cirrhosis, Experimental rosiglitazone 29.8415980055 17347453
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 29.8418564211
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 29.8412878042
MESH:D008106 Liver Cirrhosis, Experimental valsartan 29.8415619341 15504291 16872305
MESH:D008107 Liver Diseases Acetaminophen 13.4412587719 19784758 16610002 12969438 11587558 16611625 19460945 19014921
MESH:D008107 Liver Diseases Arsenic 13.4411134558
MESH:D008107 Liver Diseases Carbon Tetrachloride 13.4416246199 16964402 15830285 17285989 15720792
MESH:D008107 Liver Diseases Curcumin 13.4416956363
MESH:D008107 Liver Diseases Diethylnitrosamine 13.4417034775
MESH:D008107 Liver Diseases Phenobarbital 13.4419363144
MESH:D008107 Liver Diseases Plant Extracts 13.4417034775
MESH:D017093 Liver Failure Carbon Tetrachloride 8.8715123358
MESH:D017093 Liver Failure Galactosamine 8.8711023982
MESH:D017114 Liver Failure, Acute Acetaminophen 6.5817185352 16871587
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 6.5816899240 14706259
MESH:D008113 Liver Neoplasms marker/mechanism 21159647
MESH:D008113 Liver Neoplasms Aflatoxin B1 56.0418177683 2125692 9163691 15890375
MESH:D008113 Liver Neoplasms Arsenic 56.0416368122
MESH:D008113 Liver Neoplasms arsenic trioxide 56.0414682389
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 56.0421137059 20195826
MESH:D008113 Liver Neoplasms beta-Naphthoflavone 56.0421295105 19389873
MESH:D008113 Liver Neoplasms Butylated Hydroxytoluene 56.0418177683
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 56.0419294768
MESH:D008113 Liver Neoplasms Diethylnitrosamine 56.0412112319 20118626 19256749 19090486 21167192 20501860 19850985 21071580 18644402 19812893 21278145 15175105 19690152 18977376 19427195 19294768 9163691 18754104 20137499 18978307 15885732 20101389 19996281 20452335 16942905 19642983 20434301 2422723 19255062 19254457 21047994 19551842 19499222 18648771 19833225 2862719 19426721 19638242 20405173 20583210 12771043 10737359 20492335 19073162
MESH:D008113 Liver Neoplasms Fenofibrate 56.0418978307
MESH:D008113 Liver Neoplasms Mitomycin 56.0415113037
MESH:D008113 Liver Neoplasms perfluorooctanoic acid 56.0414757943 18709148
MESH:D008113 Liver Neoplasms Phenobarbital 56.0419073162 8742319 19812893 15975961 19482888 21047994
MESH:D008113 Liver Neoplasms pirinixic acid 56.0415890375 20007298 16377806
MESH:D008113 Liver Neoplasms Plant Extracts 56.0419168119
MESH:D008113 Liver Neoplasms Quercetin 56.0418980244
MESH:D008113 Liver Neoplasms resveratrol 56.0420405173 19073162 19321006 19812893
MESH:D008113 Liver Neoplasms sodium arsenite 56.0415276417 16712894
MESH:D008113 Liver Neoplasms Tamoxifen 56.0416684651
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 56.0416984957
MESH:D008114 Liver Neoplasms, Experimental Aflatoxin B1 32.588603461
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 32.5820377131
MESH:D008114 Liver Neoplasms, Experimental beta-Naphthoflavone 32.5818164116
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 32.5815583823 12014681
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 32.5818079962 17942915 19004024 18282651 17174075 21159647 19009564 18093689 9362446 19519916 2563599 18775883 19539802 18253720 16267830 18308698 18544905 17854601 3124819 18164116 19126423 16842330
MESH:D008114 Liver Neoplasms, Experimental Doxorubicin 32.5816842330 17085340
MESH:D008114 Liver Neoplasms, Experimental Fenofibrate 32.5818775883 18253720
MESH:D008114 Liver Neoplasms, Experimental Methylcholanthrene 32.581399818 598648
MESH:D008114 Liver Neoplasms, Experimental Phenobarbital 32.582563599 17172636 18308698 6150874 1399818
MESH:D008114 Liver Neoplasms, Experimental Quercetin 32.5819519916
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 32.5812151625
MESH:D008133 Long QT Syndrome arsenic trioxide 2.5915213294
MESH:D008171 Lung Diseases Hydrochloric Acid 8.3816784557
MESH:D008171 Lung Diseases Ozone 8.388266340 19066396
MESH:D008171 Lung Diseases sodium arsenite 8.3819095001
MESH:D055370 Lung Injury Asbestos, Crocidolite 18.5517365036
MESH:D055370 Lung Injury Hydrochloric Acid 18.5519644408 15607125 17627322 18573544 15090967 15044056 21311175 11395602 18497604 18339021 16129981 19262391 21114838 20597076
MESH:D055370 Lung Injury Lipopolysaccharides 18.5521114838
MESH:D055370 Lung Injury Oxygen 18.5518339021
MESH:D055370 Lung Injury Ozone 18.5520417186
MESH:D008175 Lung Neoplasms Aflatoxin B1 46.0814755239
MESH:D008175 Lung Neoplasms alitretinoin 46.0816413115
MESH:D008175 Lung Neoplasms Arsenic 46.0817976673 19168569 17306315
MESH:D008175 Lung Neoplasms arsenic trioxide 46.0811798837 19825857
MESH:D008175 Lung Neoplasms arsenite 46.0816809336
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 46.0820464547 20869020 17053015 18816296 18569708 6695378 18520028 20064080 20135361
MESH:D008175 Lung Neoplasms Butylated Hydroxytoluene 46.0811696405 16337739 19359593 11246140 18597497 15390079 19925653
MESH:D008175 Lung Neoplasms Curcumin 46.0819359593 16243823 18462866
MESH:D008175 Lung Neoplasms Dexamethasone 46.0811195469 15824018
MESH:D008175 Lung Neoplasms Diethylnitrosamine 46.0820512841 20970405 6695378 21163286
MESH:D008175 Lung Neoplasms Doxorubicin 46.0817418594 6189445
MESH:D008175 Lung Neoplasms Indomethacin 46.0811497255 16537180 11053908
MESH:D008175 Lung Neoplasms Isotretinoin 46.0815899809
MESH:D008175 Lung Neoplasms mangiferin 46.0818569708 18520028 18816296
MESH:D008175 Lung Neoplasms Methylcholanthrene 46.081399818 20970405 6695378 7750092 17909032 16337739 15390079 9230183 10545420 16271038 11893704 21163286 20512841
MESH:D008175 Lung Neoplasms Ozone 46.088597069 7614698
MESH:D008175 Lung Neoplasms Plant Extracts 46.0820869020
MESH:D008175 Lung Neoplasms Quercetin 46.0816280456
MESH:D008175 Lung Neoplasms sodium arsenite 46.0819931552 16712894 15276417 17306315 17077188
MESH:D008175 Lung Neoplasms Tamoxifen 46.0818625569
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 46.0811884234 19555203
MESH:D008175 Lung Neoplasms Tetradecanoylphorbol Acetate 46.0811807781
MESH:D008175 Lung Neoplasms Tobacco Smoke Pollution 46.0811091918 12111688 3440675 16288123
MESH:D008223 Lymphoma Curcumin 8.3518462866
MESH:D008223 Lymphoma decitabine 8.3519470736
MESH:D008223 Lymphoma Doxorubicin 8.3516098063
MESH:D016393 Lymphoma, B-Cell resveratrol 3.4117088997
MESH:D008228 Lymphoma, Non-Hodgkin Doxorubicin 9.9417654614
MESH:D008228 Lymphoma, Non-Hodgkin Paclitaxel 9.9414749477
MESH:D008228 Lymphoma, Non-Hodgkin resveratrol 9.9414749477
MESH:D016399 Lymphoma, T-Cell Curcumin 8.4716173963
MESH:D016399 Lymphoma, T-Cell Doxorubicin 8.4715621674
MESH:D015674 Mammary Neoplasms, Animal resveratrol 6.8615688416
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 6.8619428831
MESH:D008325 Mammary Neoplasms, Experimental Butylated Hydroxytoluene 21.461500032
MESH:D008325 Mammary Neoplasms, Experimental Doxorubicin 21.4615458769
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 21.4611408345 16891317 17203775 11807958
MESH:D008325 Mammary Neoplasms, Experimental Progesterone 21.4611408345 17203775
MESH:D008325 Mammary Neoplasms, Experimental resveratrol 21.468985016 11606380
MESH:D008325 Mammary Neoplasms, Experimental rosiglitazone 21.4616827153
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 21.4619196722 16827153 11731420 14580682 19196723
MESH:D008325 Mammary Neoplasms, Experimental Tetradecanoylphorbol Acetate 21.468985016
MESH:D020149 Manganese Poisoning Estradiol 9.4319453300
MESH:D020149 Manganese Poisoning Tamoxifen 9.4319453300
MESH:D008545 Melanoma Curcumin 18.2317885582 18462866
MESH:D008545 Melanoma decitabine 18.2317785578 16505122
MESH:D008545 Melanoma Doxorubicin 18.2316827129
MESH:D008545 Melanoma Glucose 18.2314993021
MESH:D008545 Melanoma Isotretinoin 18.2317237267
MESH:D008545 Melanoma Paclitaxel 18.2312025231 12040289 16342250
MESH:D008545 Melanoma resveratrol 18.2317992120
MESH:D008545 Melanoma sodium arsenite 18.2316487513 19082730
MESH:D008545 Melanoma Tamoxifen 18.2319393235 12393984
MESH:D008545 Melanoma Vinblastine 18.2315577320 18332650 18176117 16809738 18505091 17761969 12374674 16248763 16432458 15577323
MESH:D018328 Melanoma, Amelanotic Tamoxifen 3.2315990972
MESH:D008546 Melanoma, Experimental Acetaminophen 2.6419513568
MESH:D008569 Memory Disorders Curcumin 7.0217263510
MESH:D008569 Memory Disorders mangiferin 7.0219182383
MESH:D008654 Mesothelioma Asbestos, Crocidolite 7.3816966607 18303189 16166281
MESH:D008654 Mesothelioma Atrazine 7.381916698
MESH:D008654 Mesothelioma Doxorubicin 7.3817638057
MESH:D008659 Metabolic Diseases resveratrol 3.5017112576
MESH:D024821 Metabolic Syndrome X Fructose 7.3219165636 18497449 16815490 17098227 17261469
MESH:D024821 Metabolic Syndrome X rosiglitazone 7.3217261469
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 3.8116801185
MESH:D008679 Metaplasia Ozone 4.1310496685
MESH:D053842 Microsatellite Instability Methylnitronitrosoguanidine 4.9317671175
MESH:D008881 Migraine Disorders Indomethacin 2.9511903285
MESH:D028361 Mitochondrial Diseases Doxorubicin 3.6215792986
MESH:D018200 Mixed Tumor, Mullerian Raloxifene 4.5815863610
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 10.0116381670
MESH:D009062 Mouth Neoplasms Indomethacin 10.0112636206
MESH:D009062 Mouth Neoplasms Tobacco Smoke Pollution 10.0115006635
MESH:D052016 Mucositis Doxorubicin 3.8417415656
MESH:D009101 Multiple Myeloma arsenic trioxide 22.7915949261 19417148 14977855 19549372 11468182
MESH:D009101 Multiple Myeloma Curcumin 22.7919372569
MESH:D009101 Multiple Myeloma decitabine 22.7918172295
MESH:D009101 Multiple Myeloma Dexamethasone 22.7915867202 15744524 16118317
MESH:D009101 Multiple Myeloma Paclitaxel 22.7914749477
MESH:D009101 Multiple Myeloma Raloxifene 22.7916497877
MESH:D009101 Multiple Myeloma resveratrol 22.7916267019 17164350 17935668 17049120 14749477 16490592
MESH:D009134 Muscular Atrophy, Spinal Curcumin 9.2517962980
MESH:D009134 Muscular Atrophy, Spinal resveratrol 9.2517962980
MESH:D009135 Muscular Diseases Bezafibrate 7.6516239165
MESH:D009135 Muscular Diseases pirinixic acid 7.6516239165
MESH:D009182 Mycosis Fungoides arsenic trioxide 3.7018349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 8.6416882451 16105982
MESH:D009190 Myelodysplastic Syndromes decitabine 8.6418608210 16882708 19010910 19157545
MESH:D009190 Myelodysplastic Syndromes Dexamethasone 8.649809623
MESH:D009203 Myocardial Infarction Doxorubicin 15.6219429709 15857846
MESH:D009203 Myocardial Infarction Hydrochloric Acid 15.6218534312
MESH:D009203 Myocardial Infarction mangiferin 15.6216584858 17052832 19172585 16697266 16538859
MESH:D009203 Myocardial Infarction pirinixic acid 15.6219151258
MESH:D009203 Myocardial Infarction Quercetin 15.6219595682
MESH:D009203 Myocardial Infarction resveratrol 15.6216525036 17125593 17188708 16317513 17015251 16456233
MESH:D017202 Myocardial Ischemia Arsenic 15.4015371236
MESH:D017202 Myocardial Ischemia bivalirudin 15.4010562259
MESH:D017202 Myocardial Ischemia resveratrol 15.4017015251 17125593
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 15.4012213967
MESH:D015428 Myocardial Reperfusion Injury Estradiol 14.0516810080
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 14.0516411023
MESH:D015428 Myocardial Reperfusion Injury Quercetin 14.0519207477
MESH:D015428 Myocardial Reperfusion Injury SEA 0400 14.0515215644
MESH:D009205 Myocarditis resveratrol 3.8117322642
MESH:D020191 Myoclonic Epilepsies, Progressive Phenobarbital 3.5217484760
MESH:D009232 Myxoma Raloxifene 4.5816343187
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 7.3016624393
MESH:D009361 Neoplasm Invasiveness Curcumin 7.3018495463
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 12.509029167 3581430
MESH:D009362 Neoplasm Metastasis Doxorubicin 12.5018259882
MESH:D009362 Neoplasm Metastasis Indomethacin 12.5016537180 11239499 11053908
MESH:D009362 Neoplasm Metastasis Paclitaxel 12.5015867366
MESH:D009362 Neoplasm Metastasis Tamoxifen 12.5019393235
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.1019410462
MESH:D009369 Neoplasms alitretinoin 12.2416946489
MESH:D009369 Neoplasms Benzo(a)pyrene 12.2411141357
MESH:D009369 Neoplasms decitabine 12.2417925555 19470736 19116145
MESH:D009369 Neoplasms pirinixic acid 12.2417405874
MESH:D009369 Neoplasms Quercetin 12.2415185748
MESH:D009369 Neoplasms sodium arsenite 12.2411559025
MESH:D009374 Neoplasms, Experimental Indomethacin 10.0315625704 10663608
MESH:D009374 Neoplasms, Experimental resveratrol 10.038985016
MESH:D009374 Neoplasms, Experimental sodium arsenite 10.0320056578
MESH:D009376 Neoplasms, Hormone-Dependent Curcumin 7.6412497104
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 7.6419196722 19200415 19189210
MESH:D009389 Neovascularization, Pathologic arsenite 7.0115738583
MESH:D009389 Neovascularization, Pathologic Estradiol 7.0117289903
MESH:D009401 Nephrosis Doxorubicin 3.8316636307 16899518
MESH:D009402 Nephrosis, Lipoid Cyclosporine 3.4717954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 6.5319348381 18481113
MESH:D009404 Nephrotic Syndrome Doxorubicin 6.5315640375 16889571
MESH:D009410 Nerve Degeneration mangiferin 6.3917433543
MESH:D009410 Nerve Degeneration Rotenone 6.3918619942 15790535 17356569
MESH:D009421 Nervous System Malformations Estradiol 6.4516427766 11399458
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 6.4514600291
MESH:D009423 Nervous System Neoplasms Curcumin 4.6618462866
MESH:D009436 Neural Tube Defects Arsenic 11.6816620997
MESH:D009436 Neural Tube Defects arsenic trioxide 11.6810525206
MESH:D009436 Neural Tube Defects sodium arsenite 11.6812854658
MESH:D009436 Neural Tube Defects Tetrahydrocannabinol 11.6819040278
MESH:D019954 Neurobehavioral Manifestations Plant Extracts 4.2517168769
MESH:D009447 Neuroblastoma Doxorubicin 8.1515555623
MESH:D009447 Neuroblastoma Isotretinoin 8.1517368321
MESH:D009447 Neuroblastoma Topotecan 8.1515176712
MESH:D019636 Neurodegenerative Diseases Acetaminophen 13.4818514411
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 13.4820387270
MESH:D019636 Neurodegenerative Diseases Indomethacin 13.4812349958
MESH:D019636 Neurodegenerative Diseases resveratrol 13.4817652729
MESH:D020078 Neurogenic Inflammation Arsenic 12.6817056641
MESH:D020078 Neurogenic Inflammation Quercetin 12.6817929310
MESH:D020078 Neurogenic Inflammation resveratrol 12.6817929310
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 4.1420387270
MESH:D009503 Neutropenia Vinblastine 3.6917378895
MESH:D052556 Niemann-Pick Disease, Type C perfluorooctanoic acid 4.029802331
MESH:D009765 Obesity Curcumin 7.6419297423
MESH:D009765 Obesity Fructose 7.6417707055 18585860
MESH:D009765 Obesity pirinixic acid 7.6420558911
MESH:D009765 Obesity Plant Extracts 7.6419056576 20132043
MESH:D007752 Obstetric Labor, Premature Indomethacin 4.206374098
MESH:D009784 Occupational Diseases Hydrochloric Acid 3.9212378975
MESH:D010003 Osteoarthritis Indomethacin 3.017009135
MESH:D010014 Osteolysis Paclitaxel 4.0315867366
MESH:D010018 Osteomalacia Phenobarbital 3.4117016548
MESH:D010024 Osteoporosis Curcumin 8.2318719352
MESH:D010024 Osteoporosis Levonorgestrel 8.2312665316
MESH:D010024 Osteoporosis Raloxifene 8.2315775268 19059307 17882678
MESH:D015663 Osteoporosis, Postmenopausal Quercetin 11.7919495926
MESH:D015663 Osteoporosis, Postmenopausal Raloxifene 11.7915758505 17823083 17893378 15579764
MESH:D015663 Osteoporosis, Postmenopausal resveratrol 11.7917513867
MESH:D012516 Osteosarcoma Doxorubicin 3.3115930896
MESH:D010051 Ovarian Neoplasms Arsenic 33.4217306315
MESH:D010051 Ovarian Neoplasms arsenic trioxide 33.4212452020 16624393 19769630
MESH:D010051 Ovarian Neoplasms Curcumin 33.4218462866 19020741
MESH:D010051 Ovarian Neoplasms decitabine 33.4219331143 19259094
MESH:D010051 Ovarian Neoplasms Estradiol 33.4219401270
MESH:D010051 Ovarian Neoplasms Medroxyprogesterone Acetate 33.4217393432
MESH:D010051 Ovarian Neoplasms Mifepristone 33.4216525653
MESH:D010051 Ovarian Neoplasms Paclitaxel 33.4211161223
MESH:D010051 Ovarian Neoplasms Progesterone 33.4216525653 17393432
MESH:D010051 Ovarian Neoplasms Quercetin 33.4219005980
MESH:D010051 Ovarian Neoplasms sodium arsenite 33.4215276417 17306315
MESH:D010051 Ovarian Neoplasms U 0126 33.4216211241
MESH:D010146 Pain Acetaminophen 4.1916870215
MESH:D010146 Pain Indomethacin 4.1917627676 13679232 17440234 3291741
MESH:D010149 Pain, Postoperative Indomethacin 3.7212538197 18702446
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 20.9415580305
MESH:D010190 Pancreatic Neoplasms Curcumin 20.9419401701 19196508 17440100
MESH:D010190 Pancreatic Neoplasms decitabine 20.9419294695
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 20.9416540662
MESH:D010190 Pancreatic Neoplasms Mitomycin 20.9415113037
MESH:D010190 Pancreatic Neoplasms Phenobarbital 20.9416965848
MESH:D010190 Pancreatic Neoplasms Quercetin 20.9416965848
MESH:D010190 Pancreatic Neoplasms Tetradecanoylphorbol Acetate 20.9415976015
MESH:D010195 Pancreatitis Indomethacin 3.0615028970 17883296
MESH:D016584 Panic Disorder Ethinyl Estradiol 2.7911578682
MESH:D010212 Papilloma Plant Extracts 6.7016517061 15173996
MESH:D010212 Papilloma Tetradecanoylphorbol Acetate 6.7012065085 8330346 18404319 18922899
MESH:D010235 Paraganglioma arsenic trioxide 3.2719927285
MESH:D010257 Paraneoplastic Syndromes Indomethacin 4.7416537180
MESH:D010300 Parkinson Disease Atrazine 6.1217218051
MESH:D010300 Parkinson Disease mangiferin 6.1217433543
MESH:D010300 Parkinson Disease Rotenone 6.1219114014 16412576 16140633 18191903 15451049 19232380 11445065 18619942 11535288
MESH:D020734 Parkinsonian Disorders Indomethacin 6.5612349958
MESH:D020734 Parkinsonian Disorders Rotenone 6.5615574749 15795934 18197244 15927086
MESH:D051302 Paroxysmal Hemicrania Indomethacin 4.7411903285
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 3.2812520081
MESH:D010437 Peptic Ulcer Indomethacin 4.1911148446
MESH:D010518 Periodontitis Indomethacin 9.1917225004
MESH:D010518 Periodontitis mangiferin 9.1919026997
MESH:D010523 Peripheral Nervous System Diseases Arsenic 3.2716093927
MESH:D016491 Peripheral Vascular Diseases Arsenic 9.9316905509 6392382 15371236
MESH:D016491 Peripheral Vascular Diseases Cadmium 9.9315687053
MESH:D010538 Peritonitis Ozone 3.2116369182
MESH:D003557 Phyllodes Tumor Doxorubicin 4.1817983394
OMIM:613329 PLASMINOGEN ACTIVATOR INHIBITOR-1 DEFICIENCY marker/mechanism
MESH:D010995 Pleural Diseases Asbestos, Crocidolite 3.9610923243
MESH:D010997 Pleural Neoplasms Doxorubicin 4.1817638057
MESH:D011014 Pneumonia Butylated Hydroxytoluene 13.2011893704
MESH:D011014 Pneumonia Lipopolysaccharides 13.2011605937 12224865
MESH:D011014 Pneumonia Ozone 13.2018929643 18007984 18381685
MESH:D011015 Pneumonia, Aspiration Hydrochloric Acid 4.4218573544 15607125 15970105 18497604
MESH:D011085 Polycystic Ovary Syndrome ethinyl estradiol-desogestrel combination 8.1617105841
MESH:D011085 Polycystic Ovary Syndrome Simvastatin 8.1617105841
MESH:D017499 Porokeratosis alitretinoin 5.0316144296
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 2.6518163543
MESH:D011230 Precancerous Conditions Cyclosporine 15.0912371664
MESH:D011230 Precancerous Conditions Diethylnitrosamine 15.092563599
MESH:D011230 Precancerous Conditions Phenobarbital 15.092563599
MESH:D011230 Precancerous Conditions Quercetin 15.0919056647
MESH:D054198 Precursor Cell Lymphoblastic Leukemia-Lymphoma Dexamethasone 2.9221297632
MESH:D047928 Premature Birth Indomethacin 4.1917000239
MESH:D011297 Prenatal Exposure Delayed Effects Isotretinoin 15.6218769834
MESH:D011297 Prenatal Exposure Delayed Effects perfluorooctanoic acid 15.6217132714
MESH:D011297 Prenatal Exposure Delayed Effects resveratrol 15.6216679765
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 15.6211896295 11118676 11399792 11222880
MESH:D055728 Primary Myelofibrosis decitabine 3.7917616702
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 3.0120887781
MESH:D011471 Prostatic Neoplasms marker/mechanism 16172807
MESH:D011471 Prostatic Neoplasms Arsenic 6.8416140617
MESH:D011471 Prostatic Neoplasms arsenic trioxide 6.8419131511
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 6.8417292933
MESH:D011471 Prostatic Neoplasms bicalutamide 6.8418487222 19240160 15638997 17914592 19011039
MESH:D011471 Prostatic Neoplasms Cadmium 6.8417075824
MESH:D011471 Prostatic Neoplasms Cholecalciferol 6.8417024972
MESH:D011471 Prostatic Neoplasms Curcumin 6.8412497104 18156803 15129424 18226269 18769126 10851300 11398177
MESH:D011471 Prostatic Neoplasms Doxorubicin 6.8416888761 15897917 16729912 18437689 16868541 15749863
MESH:D011471 Prostatic Neoplasms Estradiol 6.8416740699
MESH:D011471 Prostatic Neoplasms Paclitaxel 6.8416356831 17172428 16729912 17136230
MESH:D011471 Prostatic Neoplasms Plant Extracts 6.8414666653 17804756
MESH:D011471 Prostatic Neoplasms Quercetin 6.8414715546 17292933
MESH:D011471 Prostatic Neoplasms Raloxifene 6.8416536755 15731164 16220300
MESH:D011471 Prostatic Neoplasms resveratrol 6.8417636462 16731767 17675339 15767336 17804756 17718901
MESH:D011471 Prostatic Neoplasms sodium arsenite 6.8416039940
MESH:D011471 Prostatic Neoplasms Tamoxifen 6.8415067354
MESH:D011507 Proteinuria Arsenic 14.9321343184
MESH:D011507 Proteinuria Indomethacin 14.9311849393
MESH:D011507 Proteinuria telmisartan 14.9316077267
MESH:D011507 Proteinuria valsartan 14.9312164870 18344623 17664856
MESH:D011537 Pruritus Ethinyl Estradiol 6.8716919318 15861022
MESH:D011537 Pruritus Levonorgestrel 6.8715861022
MESH:D019310 Pseudolymphoma Phenobarbital 3.5312752131
MESH:D011565 Psoriasis Cyclosporine 1.7916882103
MESH:D011596 Psychomotor Disorders Isotretinoin 4.9618769834
MESH:D001261 Pulmonary Atelectasis Hydrochloric Acid 5.0420597076
MESH:D011654 Pulmonary Edema Hydrochloric Acid 4.2515090967
MESH:D011656 Pulmonary Emphysema Curcumin 3.6719168576
MESH:D011658 Pulmonary Fibrosis Asbestos, Crocidolite 6.8715814490 17322281 17975199 17365031
MESH:D011658 Pulmonary Fibrosis pirfenidone 6.8712832656
MESH:D011658 Pulmonary Fibrosis valsartan 6.8717241526
MESH:D011693 Purpura Raloxifene 4.5815770314
MESH:D011833 Radiation Injuries, Experimental mangiferin 5.4315830843
MESH:D051437 Renal Insufficiency Doxorubicin 3.3017922066
MESH:D051436 Renal Insufficiency, Chronic resveratrol 4.6116325855
MESH:D015427 Reperfusion Injury pirinixic acid 4.6319058328
MESH:D015427 Reperfusion Injury resveratrol 4.6317058453 16314181 15827377 17520802 16317513
MESH:D012120 Respiration Disorders Chlorine 4.2418579056
MESH:D012128 Respiratory Distress Syndrome, Adult Curcumin 14.4518379247 10666014
MESH:D012128 Respiratory Distress Syndrome, Adult Dexamethasone 14.4518379247 11700416
MESH:D012128 Respiratory Distress Syndrome, Adult Hydrochloric Acid 14.4516129981 18339021 17627322 18549715 16784557
MESH:D012128 Respiratory Distress Syndrome, Adult Oxygen 14.4517627322 18339021
MESH:D012130 Respiratory Hypersensitivity Lipopolysaccharides 3.0310835634
MESH:D012133 Respiratory Paralysis Hydrochloric Acid 5.3911510729
MESH:D012135 Respiratory Sounds Atrazine 7.0311874814
MESH:D012135 Respiratory Sounds Tobacco Smoke Pollution 7.0318410779
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 2.9218990726
MESH:D012140 Respiratory Tract Diseases Hydrochloric Acid 4.2120516732
MESH:D012208 Rhabdomyosarcoma decitabine 3.5119155313
MESH:D012468 Salivary Gland Neoplasms Progesterone 2.4118045962
MESH:D012509 Sarcoma Curcumin 6.7418462866
MESH:D012509 Sarcoma Doxorubicin 6.7417710206 17203757 16767912 15675481 15625365 18313854
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 7.2616646077
MESH:D012512 Sarcoma, Ewing's Doxorubicin 7.2614601052 16326096
MESH:D012514 Sarcoma, Kaposi Doxorubicin 3.8417846226
MESH:D012554 Schistosomiasis japonica Quercetin 4.5716862918
MESH:D012559 Schizophrenia Methionine 3.5115737665
MESH:D012640 Seizures Kainic Acid 6.2816336964 10686065 1641125 19414003 19186208 15686955 14637104 17827730 18657176
MESH:D012640 Seizures Mecamylamine 6.2812660363
MESH:D012640 Seizures Phenobarbital 6.283137016 16876388 4039156 11442880
MESH:D003294 Seizures, Febrile Phenobarbital 3.876407741
MESH:D018805 Sepsis Curcumin 3.2618389075
MESH:D012772 Shock, Septic mangiferin 4.2915177305
MESH:D012852 Sinusitis Phenylephrine 3.757327846
MESH:D012871 Skin Diseases Arsenic 4.1318709164 19834688 17050553 16759981 17548696 15952646 16702368 17453740 6392382 16353154 17938729
MESH:D012871 Skin Diseases monomethylarsonous acid 4.1317431481
MESH:D012878 Skin Neoplasms Arsenic 33.5417050553 17976673 16251483 17029826 15504454 19538983
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 33.5419755658 10029692
MESH:D012878 Skin Neoplasms Doxorubicin 33.5415692506
MESH:D012878 Skin Neoplasms Glucose 33.5414993021
MESH:D012878 Skin Neoplasms Plant Extracts 33.5416517061 15173996
MESH:D012878 Skin Neoplasms resveratrol 33.5415837718 8985016
MESH:D012878 Skin Neoplasms sodium arsenite 33.5419524636 18572023
MESH:D012878 Skin Neoplasms tert-Butylhydroperoxide 33.548532709
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 33.5416192470
MESH:D012878 Skin Neoplasms Tetradecanoylphorbol Acetate 33.548985016 18404319 8330346 11807781 12065085
MESH:D012878 Skin Neoplasms Tobacco Smoke Pollution 33.5418590791
MESH:D012893 Sleep Disorders Kainic Acid 4.7519414003
MESH:D012983 Soft Tissue Neoplasms Doxorubicin 3.6317203757 15625365 16767912
MESH:D013088 Spermatocele Ethinyl Estradiol 8.3516709447
MESH:D013088 Spermatocele Tamoxifen 8.3516709447
MESH:D013119 Spinal Cord Injuries Progesterone 7.7216503802 15862959
MESH:D013119 Spinal Cord Injuries Tamoxifen 7.7219457130
MESH:D016135 Spinal Dysraphism sodium arsenite 3.0112854658
MESH:D013272 Stomach Diseases Dexamethasone 7.2315472012
MESH:D013272 Stomach Diseases Indomethacin 7.2318209964 16184426 17638125 15038085 16280098 16113693 17160473 15472012 10192188 10215738 18545984 10486359 17207306
MESH:D013274 Stomach Neoplasms marker/mechanism 16367923
MESH:D013274 Stomach Neoplasms arsenic trioxide 5.9117007042
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 5.912093021 20155912
MESH:D013274 Stomach Neoplasms decitabine 5.9119037991
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 5.9118456281
MESH:D013274 Stomach Neoplasms Indomethacin 5.9115609394
MESH:D013274 Stomach Neoplasms Paclitaxel 5.9118506536 18396642
MESH:D013276 Stomach Ulcer Curcumin 20.8816631530 19188055
MESH:D013276 Stomach Ulcer Dexamethasone 20.8815138204
MESH:D013276 Stomach Ulcer Hydrochloric Acid 20.8815309881 16755016 17189318
MESH:D013276 Stomach Ulcer Indomethacin 20.8812077510 10878458 16397915 17977527 18299717 16631530 12787963 11906479 16252198 17918041 18543354 1323529 11145282 17895592 12500499 18209962 17654042 18431645 14567935 18181030 16934674 10423059 17657623 17627676 11729361 16755016 12467913 15104355 18237397 11595431 16150113 11595415 18193104 11523592 10750652 15138204 15255614 18087811 18726076 17135157 16169175 12498302
MESH:D013276 Stomach Ulcer mangiferin 20.8817918041
MESH:D013276 Stomach Ulcer pimagedine 20.8818209962
MESH:D013276 Stomach Ulcer Plant Extracts 20.8817135157 12787963 15255614 18193104 18237397
MESH:D020521 Stroke bivalirudin 6.7714683561
MESH:D020521 Stroke Raloxifene 6.7716837676
OMIM:601367 STROKE, ISCHEMIC resveratrol 3.6216321402
MESH:D013398 Sudden Infant Death Oxygen 4.5912563064
MESH:D024801 Tauopathies Paclitaxel 3.8616930453
MESH:D013705 Temporomandibular Joint Disorders Plant Extracts 4.5117997062
MESH:D013921 Thrombocytopenia bivalirudin 7.5716893407 16651880
MESH:D013921 Thrombocytopenia Lipopolysaccharides 7.5715821434
MESH:D019851 Thrombophilia Ethinyl Estradiol 13.3311994571
MESH:D019851 Thrombophilia ethinyl estradiol-desogestrel combination 13.3311994571
MESH:D019851 Thrombophilia Gestodene 13.3311994571
MESH:D013927 Thrombosis bivalirudin 10.838456428 14593979 16893407 15979436 9125671
MESH:D013927 Thrombosis Ethinyl Estradiol 10.8315669648
MESH:D013927 Thrombosis Gestodene 10.8315669648
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 2.9312697716
MESH:D013964 Thyroid Neoplasms 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine 22.0916940797
MESH:D013964 Thyroid Neoplasms arsenic trioxide 22.0919014326
MESH:D013964 Thyroid Neoplasms decitabine 22.0917967635
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 22.097505956
MESH:D013964 Thyroid Neoplasms Doxorubicin 22.0917909728 16010429
MESH:D013964 Thyroid Neoplasms Indomethacin 22.0914736730 18791128 11352223
MESH:D013964 Thyroid Neoplasms Phenobarbital 22.091399818
MESH:D013978 Tibial Fractures Estradiol 10.4919048282
MESH:D013978 Tibial Fractures Raloxifene 10.4919048282
MESH:D014062 Tongue Neoplasms resveratrol 3.3616227395
MESH:D016171 Torsades de Pointes arsenic trioxide 3.0215213294
MESH:D014235 Trichinellosis mangiferin 5.0914669257
MESH:D014456 Ulcer Indomethacin 3.9417380554 10574470
MESH:D001749 Urinary Bladder Neoplasms Arsenic 33.7717976673 11144890 15987713 19322015 17306315 18640142 19429237
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 33.7712973940 11780464 20435036 12845720
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 33.7717053015
MESH:D001749 Urinary Bladder Neoplasms Curcumin 33.7718593936
MESH:D001749 Urinary Bladder Neoplasms decitabine 33.7717616700 19087683
MESH:D001749 Urinary Bladder Neoplasms Doxorubicin 33.7717653716
MESH:D001749 Urinary Bladder Neoplasms monomethylarsonous acid 33.7720375083
MESH:D001749 Urinary Bladder Neoplasms Quercetin 33.7716720314
MESH:D001749 Urinary Bladder Neoplasms Raloxifene 33.7717572228
MESH:D001749 Urinary Bladder Neoplasms sodium arsenite 33.7711723127 17306315 16452187 16712894
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 33.778653321 17572228 16712894
MESH:D001749 Urinary Bladder Neoplasms Tobacco Smoke Pollution 33.7712846360
MESH:D014565 Urogenital Neoplasms Curcumin 4.3118462866
MESH:D014581 Urticaria Acetaminophen 2.1010982225
MESH:D002583 Uterine Cervical Neoplasms resveratrol 6.7417473185
MESH:D002583 Uterine Cervical Neoplasms sodium arsenite 6.7411813266
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 10.9214692618
MESH:D014594 Uterine Neoplasms resveratrol 10.9217044934
MESH:D014594 Uterine Neoplasms sulindac sulfide 10.9218645019
MESH:D014604 Uveal Neoplasms decitabine 3.9417785578
MESH:D014605 Uveitis Cyclosporine 8.561336536
MESH:D014605 Uveitis Dexamethasone 8.561336536
MESH:D014625 Vaginal Neoplasms Vinblastine 4.1115577323
MESH:D014652 Vascular Diseases Arsenic 8.6917056641
MESH:D014652 Vascular Diseases sodium arsenite 8.6917056641
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 3.6212125929
MESH:D054556 Venous Thromboembolism Raloxifene 4.2416837676
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 12.9014671159 15869587
MESH:D020246 Venous Thrombosis ethinyl estradiol-desogestrel combination 12.9015869587
MESH:D020246 Venous Thrombosis Levonorgestrel 12.9015869587
MESH:D018487 Ventricular Dysfunction, Left Doxorubicin 11.8916364871 17678736 17334414 17638931
MESH:D018487 Ventricular Dysfunction, Left Plant Extracts 11.8918097624
MESH:D018487 Ventricular Dysfunction, Left resveratrol 11.8917488730
MESH:D020257 Ventricular Remodeling Plant Extracts 9.7118097624
MESH:D020257 Ventricular Remodeling valsartan 9.7119027736
MESH:D014839 Vomiting Indomethacin 3.7811897121
MESH:D014846 Vulvar Neoplasms Raloxifene 4.5816343187
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 3.2815886252
MESH:D014947 Wounds and Injuries Plant Extracts 3.4520213670 19894650
MESH:D014985 Xerophthalmia Cyclosporine 3.4717120751
Pathway ID Pathway Name
KEGG:05142 Chagas disease (American trypanosomiasis)
REACT:24941 Circadian Clock
KEGG:04610 Complement and coagulation cascades
REACT:604 Hemostasis
KEGG:04115 p53 signaling pathway
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA261
    • No data
    Releated disease ID Related disease Name
    PA447278Depression
    PA447321Depressive Disorder, Major
    PA447207Depressive Disorder
    PA445848Thromboembolism
    Releated drug ID Related drug Name
    PA449015citalopram
    PA449673fluoxetine
    PA449470epinephrine
    Drug Bank Top
    Drugbank ID Action Drug Name Description
    DB00009 - Alteplase Thrombolytic Agents
    DB00013 - Urokinase Thrombolytic Agents
    DB00015 - Reteplase Thrombolytic Agents
    DB00029 - Anistreplase Thrombolytic Agents
    DB00031 - Tenecteplase Thrombolytic Agents
    DB00055 - Drotrecogin alfa Antisepsis Agents
    DB00197 antagonist Troglitazone Antineoplastic Agents;Hypoglycemic Agents;Vasodilator Agents;Platelet Aggregation Inhibitors;Fibrinolytic Agents
    DB01093 - Synotic Otic Solution Free Radical Scavengers;Analgesics, Non-Narcotic;Solvents;Cryoprotective Agents
    No data
    No data
    No data

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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