AutismKB 2.0

Annotation Detail for CYHR1


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Basic Information Top
Gene Symbol:CYHR1 ( CHRP,KIAA0496,MGC13010 )
Gene Full Name: cysteine/histidine-rich 1
Band: 8q24.3
Quick LinksEntrez ID:50626; OMIM: NA; Uniprot ID:CYHR1_HUMAN; ENSEMBL ID: ENSG00000187954; HGNC ID: 17806
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000082 Acetaminophen Acetaminophen affects the expression of CYHR1 mRNAaffects expression 17562736
C006253 pirinixic acid pirinixic acid results in increased expression of CYHR1 mRNAincreases expression 17426115
D012645 Selenomethionine Selenomethionine affects the expression of CYHR1 mRNAaffects expression 17222674
C004648 testosterone enanthate testosterone enanthate affects the expression of CYHR1 mRNAaffects expression 17440010
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D055371 Acute Lung Injury pirinixic acid 3.5818653653
MESH:D018248 Adenoma, Liver Cell pirinixic acid 4.1116434500
MESH:D000799 Angioedema Acetaminophen 4.5710982225
MESH:D001321 Autistic Disorder Acetaminophen 1.4018445737
MESH:D001778 Blood Coagulation Disorders pirinixic acid 3.5719483382
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 1.413084413
MESH:D002386 Cataract Acetaminophen 2.7910977129
MESH:D002779 Cholestasis pirinixic acid 3.1219176532
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.5718249437
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 1.672444490 17906064 12153990 14725611 12540782 16109766 14550746 11739529 19370779 10915739 19164858 11834606 17562736 11287661 10774834 11461765 16485898 19739265 12594235 19416960 10663392 16781746 16393943 15968718 19923254 16177239 11529661 11743745 19420014 18713872 11421492 12705907 15619225 16227642 14986274 18071297 12392966 19085960 17522070 16081117 12958197
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.8219426721
MESH:D004487 Edema pirinixic acid 2.9012083418
MESH:D005234 Fatty Liver pirinixic acid 3.1919236843 20131406
MESH:D005756 Gastritis Acetaminophen 4.4016983495
MESH:D006333 Heart Failure pirinixic acid 2.7620558911
MESH:D006529 Hepatomegaly pirinixic acid 3.5516221962 18467677 19176532 19772884
MESH:D019247 HIV Wasting Syndrome testosterone enanthate 6.4717440010
MESH:D006930 Hyperalgesia Acetaminophen 3.0216870215
MESH:D006943 Hyperglycemia pirinixic acid 3.5820558911
MESH:D007333 Insulin Resistance pirinixic acid 2.8716306350
MESH:D007674 Kidney Diseases Acetaminophen 2.4015629191 12587719
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 1.3515474484
MESH:D008107 Liver Diseases Acetaminophen 1.7012969438 11587558 16611625 19014921 12587719 19460945 16610002 19784758
MESH:D017114 Liver Failure, Acute Acetaminophen 3.6316871587 17185352
MESH:D008113 Liver Neoplasms pirinixic acid 1.9320007298 16377806 15890375
MESH:D008546 Melanoma, Experimental Acetaminophen 4.1319513568
MESH:D009135 Muscular Diseases pirinixic acid 4.0716239165
MESH:D009203 Myocardial Infarction pirinixic acid 2.2719151258
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 3.2516411023
MESH:D009369 Neoplasms pirinixic acid 2.1117405874
MESH:D019636 Neurodegenerative Diseases Acetaminophen 3.2118514411
MESH:D009765 Obesity pirinixic acid 1.8820558911
MESH:D010146 Pain Acetaminophen 2.7316870215
MESH:D015427 Reperfusion Injury pirinixic acid 2.5519058328
MESH:D014581 Urticaria Acetaminophen 3.4410982225
No data
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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018