AutismKB 2.0

Annotation Detail for ASAP1


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:ASAP1 ( AMAP1,CENTB4,DDEF1,KIAA1249,PAG2,PAP,ZG14P )
Gene Full Name: ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
Band: 8q24.21-q24.22
Quick LinksEntrez ID:50807; OMIM: 605953; Uniprot ID:ASAP1_HUMAN; ENSEMBL ID: ENSG00000153317; HGNC ID: 2720
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa04144Endocytosis
hsa04666Fc gamma R-mediated phagocytosis
No data
Pathway IDPathway Name
200167Arf1 pathway
200192Signaling events mediated by focal adhesion kinase
No data
No data
Related Diseases/Disorders Top
No data
No data
Desease Name
multiple sclerosis
IMMUNE
Desease Name
Multiple sclerosis
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D001564 Benzo(a)pyrene Benzo(a)pyrene results in decreased expression of ASAP1 mRNAdecreases expression 20064835
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 2.0820464547 20127859
MESH:D000236 Adenoma Benzo(a)pyrene 2.926695378
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 4.9819183758
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 1.9817474063 20146248
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 2.1620419170
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 2.1016530937
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 2.8920471113
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 2.1921137059 20195826
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 1.5718816296 20064080 18569708 20869020 17053015 20135361 18520028 6695378 20464547
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 3.6216381670
MESH:D009369 Neoplasms Benzo(a)pyrene 2.3811141357
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 2.8917292933
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 2.5719755658 10029692
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 1.5620155912 2093021
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 2.3317053015
Pathway ID Pathway Name
KEGG:04144 Endocytosis
KEGG:04666 Fc gamma R-mediated phagocytosis
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA164716055
    • No data
    Releated disease ID Related disease Name
    PA446155Precursor Cell Lymphoblastic Leukemia-Lymphoma
    Releated drug ID Related drug Name
    PA448976choline
    Drug Bank Top

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


    Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved