AutismKB 2.0

Annotation Detail for NSDHL


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:NSDHL ( H105E3,SDR31E1,XAP104 )
Gene Full Name: NAD(P) dependent steroid dehydrogenase-like
Band: Xq28
Quick LinksEntrez ID:50814; OMIM: 300275; Uniprot ID:NSDHL_HUMAN; ENSEMBL ID: ENSG00000147383; HGNC ID: 13398
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Pathway IDPathway Name
PWY66-341cholesterol biosynthesis I
PWY66-4cholesterol biosynthesis III (via desmosterol)
PWY66-3cholesterol biosynthesis II (via 24,25-dihydrolanosterol)
PWY-6074zymosterol biosynthesis
Pathway IDPathway Name
hsa01100Metabolic pathways
hsa00100Steroid biosynthesis
Pathway IDPathway Name
Metabolism of lipids and lipoproteins
No data
No data
Pathway IDPathway Name
500825Cholesterol biosynthesis
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C049325 1,2-dithiol-3-thione 1,2-dithiol-3-thione results in decreased expression of NSDHL mRNAdecreases expression 15302862
C003585 22-hydroxycholesterol 22-hydroxycholesterol results in decreased expression of NSDHL mRNAdecreases expression 19426978
C016403 2,4-dinitrotoluene 2,4-dinitrotoluene affects the expression of NSDHL mRNAaffects expression 21346803
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene affects the expression of NSDHL mRNAaffects expression 21346803
C009505 4,4'-diaminodiphenylmethane 4,4'-diaminodiphenylmethane results in decreased expression of NSDHL mRNAdecreases expression 18648102
D000082 Acetaminophen Acetaminophen affects the expression of NSDHL mRNAaffects expression 17562736
D016604 Aflatoxin B1 Aflatoxin B1 affects the expression of NSDHL proteinaffects expression 20106945
C430898 AGN 194204 AGN 194204 results in increased expression of NSDHL mRNAincreases expression 15302862
D001564 Benzo(a)pyrene Benzo(a)pyrene results in decreased expression of NSDHL mRNAdecreases expression 20713471
D016572 Cyclosporine Cyclosporine results in decreased expression of NSDHL mRNAdecreases expression 20106945
D004041 Dietary Fats Dietary Fats results in decreased expression of NSDHL mRNAdecreases expression 18042831
15238619
D004997 Ethinyl Estradiol Ethinyl Estradiol results in decreased expression of NSDHL mRNAdecreases expression 17108234
D011345 Fenofibrate Fenofibrate results in increased expression of NSDHL mRNAincreases expression 11798191
C056933 fumonisin B1 fumonisin B1 results in decreased expression of NSDHL mRNAdecreases expression 16221962
D006830 Hydralazine [Hydralazine co-treated with Valproic Acid] results in increased expression of NSDHL mRNAaffects cotreatment|increases expression 17183730
D008748 Methylcholanthrene Methylcholanthrene results in decreased expression of NSDHL mRNAdecreases expression 20713471
C041786 palm oil palm oil results in decreased expression of NSDHL mRNAdecreases expression 18042831
D010634 Phenobarbital Phenobarbital affects the expression of NSDHL mRNAaffects expression 19136022
C006253 pirinixic acid pirinixic acid affects the expression of NSDHL mRNAaffects expression 19136022
C006253 pirinixic acid pirinixic acid results in decreased expression of NSDHL mRNAdecreases expression 18445702
C006253 pirinixic acid pirinixic acid results in increased expression of NSDHL mRNAincreases expression 15302862
11798191
17950772
16221962
C006253 pirinixic acid PPARA protein promotes the reaction [pirinixic acid results in increased expression of NSDHL mRNA]increases expression|increases reaction 17950772
D011374 Progesterone Progesterone results in increased expression of NSDHL mRNAincreases expression 18070364
D014284 Triiodothyronine Triiodothyronine results in increased expression of NSDHL mRNAincreases expression 15953391
D013752 Tetracycline Tetracycline results in increased expression of NSDHL mRNAincreases expression 16917069
C423915 TO-901317 TO-901317 results in increased expression of NSDHL mRNAincreases expression 15302862
D014635 Valproic Acid [Hydralazine co-treated with Valproic Acid] results in increased expression of NSDHL mRNAaffects cotreatment|increases expression 17183730
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Phenobarbital 7.966195326
MESH:D000014 Abnormalities, Drug-Induced Valproic Acid 7.968875741
MESH:D000015 Abnormalities, Multiple Valproic Acid 3.7719490988
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.7717505938
MESH:D055371 Acute Lung Injury pirinixic acid 2.9618653653
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 4.0320464547 20127859
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 4.0314692618
MESH:D000236 Adenoma 4,4'-diaminodiphenylmethane 10.653712494
MESH:D000236 Adenoma Benzo(a)pyrene 10.656695378
MESH:D000236 Adenoma Methylcholanthrene 10.656695378 10545420
MESH:D018248 Adenoma, Liver Cell Phenobarbital 9.5417620307
MESH:D018248 Adenoma, Liver Cell pirinixic acid 9.5416434500
MESH:D000550 Amblyopia Valproic Acid 5.0617688650
MESH:D000799 Angioedema Acetaminophen 3.6710982225
MESH:D001008 Anxiety Disorders Valproic Acid 3.4417497229
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 3.9019183758
MESH:D001161 Arteriosclerosis Dietary Fats 9.3415238619
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 9.3411256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 2.5615885639
MESH:D050197 Atherosclerosis Methylcholanthrene 3.3511922910
MESH:D001321 Autistic Disorder Acetaminophen 1.8518445737
MESH:D001321 Autistic Disorder Valproic Acid 1.8518985861 16609825 18558336 20603192 17507914 17688650 18316065 17157402 15238991 18940202 18396377 19232924 18177632 19460635 18775368
MESH:D001660 Biliary Tract Diseases 4,4'-diaminodiphenylmethane 4.851440618 11289319
MESH:D001714 Bipolar Disorder Valproic Acid 2.9917594078 20046352
MESH:D001778 Blood Coagulation Disorders pirinixic acid 2.9919483382
MESH:D001848 Bone Diseases, Developmental Valproic Acid 3.298888407
MESH:D020201 Brain Hemorrhage, Traumatic Progesterone 5.1717868700
MESH:D001930 Brain Injuries Progesterone 4.0915665606 15845082 15380490
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 1.9717474063 20146248
MESH:D001943 Breast Neoplasms Dietary Fats 1.9720435547
MESH:D001943 Breast Neoplasms Methylcholanthrene 1.9717474063
MESH:D001943 Breast Neoplasms Progesterone 1.9717614352 15562024 16175315
MESH:D002277 Carcinoma Methylcholanthrene 3.8310545420
MESH:D006528 Carcinoma, Hepatocellular 2,4-dinitrotoluene 11.0216705839
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 11.0216705839
MESH:D006528 Carcinoma, Hepatocellular 4,4'-diaminodiphenylmethane 11.027296757 3581430
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 11.023084413
MESH:D006528 Carcinoma, Hepatocellular Aflatoxin B1 11.0221507988 12907637 12619106
MESH:D006528 Carcinoma, Hepatocellular Phenobarbital 11.021701930 17173139 20007298 20935162 6705139
MESH:D002292 Carcinoma, Renal Cell 4,4'-diaminodiphenylmethane 2.607296757
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 2.0020419170
MESH:D002386 Cataract Acetaminophen 2.4810977129
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 15.076135515
MESH:D002471 Cell Transformation, Neoplastic 4,4'-diaminodiphenylmethane 15.077505956
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 15.0712371664
MESH:D002471 Cell Transformation, Neoplastic Methylcholanthrene 15.0716192471
MESH:D002493 Central Nervous System Diseases Phenobarbital 4.084080065
MESH:D002659 Child Development Disorders, Pervasive Valproic Acid 2.6520734317
MESH:D002779 Cholestasis 4,4'-diaminodiphenylmethane 18.179022650 19486331
MESH:D002779 Cholestasis Cyclosporine 18.1719486331
MESH:D002779 Cholestasis Ethinyl Estradiol 18.1715861022 17333356 16105132 17110522 17681005 11677210 16919318
MESH:D002779 Cholestasis pirinixic acid 18.1719176532
OMIM:308050 CONGENITAL HEMIDYSPLASIA WITH ICHTHYOSIFORM ERYTHRODERMA AND LIMB DEFECTS marker/mechanism
MESH:D019465 Craniofacial Abnormalities Valproic Acid 1.8916575769 8888407 17688650
MESH:D003490 Cyanosis 2,4-dinitrotoluene 10.3318551238
MESH:D003490 Cyanosis 2,6-dinitrotoluene 10.3318551238
MESH:D017449 Dermatitis, Allergic Contact 4,4'-diaminodiphenylmethane 2.6411906362 12868966 11298694 14531868 2524372 8156756 8970840 18759878
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.3518249437
MESH:D003877 Dermatitis, Contact 4,4'-diaminodiphenylmethane 3.333621924 2952479
MESH:D003929 Diabetic Neuropathies Progesterone 4.3217187935
MESH:D056486 Drug-Induced Liver Injury 2,4-dinitrotoluene 17.9021346803 18551238
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 17.9021346803 18551238
MESH:D056486 Drug-Induced Liver Injury 4,4'-diaminodiphenylmethane 17.9018692083 18648102 1440618 11289319 18289764 8291058 6482804 6679447 7440962 9653073 9022650 16192314 9328219
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 17.9012392966 16227642 12594235 16781746 16485898 11461765 18071297 12958197 10663392 16081117 12540782 14725611 19370779 16109766 12705907 15619225 17906064 14986274 10774834 19923254 14550746 19739265 18713872 11287661 17562736 19085960 11529661 15968718 12153990 19416960 11743745 2444490 19420014 11834606 19164858 16177239 11739529 11421492 16393943 17522070 10915739
MESH:D056486 Drug-Induced Liver Injury fumonisin B1 17.9016221962
MESH:D056486 Drug-Induced Liver Injury Tetracycline 17.9017522070
MESH:D056486 Drug-Induced Liver Injury Valproic Acid 17.901733752 19641884
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 3.9319426721
MESH:D050171 Dyslipidemias Dietary Fats 8.5518367378
MESH:D050171 Dyslipidemias Fenofibrate 8.5516707586
MESH:D004421 Dystonia Phenobarbital 9.901851702
MESH:D004421 Dystonia Valproic Acid 9.901851702
MESH:D004487 Edema pirinixic acid 2.3312083418
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 8.4812538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Progesterone 8.4817692515
MESH:D016889 Endometrial Neoplasms Fenofibrate 3.9816569247
MESH:D004715 Endometriosis Progesterone 3.6116134523
MESH:D004831 Epilepsies, Myoclonic Phenobarbital 10.233659116
MESH:D004831 Epilepsies, Myoclonic Valproic Acid 10.2317275665 3659116
MESH:D004828 Epilepsies, Partial Phenobarbital 9.403922381 11558140
MESH:D004828 Epilepsies, Partial Valproic Acid 9.403922381 16628512
MESH:D004827 Epilepsy Phenobarbital 6.3820417680
MESH:D004827 Epilepsy Valproic Acid 6.3818234410 20417680
MESH:D004832 Epilepsy, Absence Phenobarbital 8.386401628
MESH:D004832 Epilepsy, Absence Valproic Acid 8.386254150 7562514 6426943
MESH:D017029 Epilepsy, Complex Partial Phenobarbital 10.737750514
MESH:D017029 Epilepsy, Complex Partial Valproic Acid 10.737750514
MESH:D004830 Epilepsy, Tonic-Clonic Phenobarbital 9.903659116
MESH:D004830 Epilepsy, Tonic-Clonic Valproic Acid 9.903659116
MESH:D004938 Esophageal Neoplasms 4,4'-diaminodiphenylmethane 4.213581430
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 4.2116530937
MESH:D005234 Fatty Liver Cyclosporine 28.6919224547
MESH:D005234 Fatty Liver Dietary Fats 28.6917967931 19551842 19004024 18296743
MESH:D005234 Fatty Liver Ethinyl Estradiol 28.6915345470
MESH:D005234 Fatty Liver pirinixic acid 28.6919236843 20131406
MESH:D005234 Fatty Liver Tetracycline 28.6919224547 16917069
MESH:D005234 Fatty Liver Valproic Acid 28.6914986274 19224547
MESH:D005315 Fetal Diseases Valproic Acid 4.7116575769
MESH:D005317 Fetal Growth Retardation Valproic Acid 3.968888407 18558336
MESH:D005350 Fibroma 4,4'-diaminodiphenylmethane 4.856705139
MESH:D005354 Fibrosarcoma Methylcholanthrene 4.7714633661 10962813
MESH:D005355 Fibrosis Cyclosporine 8.1312168785 12639820
MESH:D005355 Fibrosis Dietary Fats 8.1318296743
MESH:D005756 Gastritis Acetaminophen 3.5016983495
MESH:D005885 Gingival Hyperplasia Cyclosporine 4.058708960
MESH:D006042 Goiter 4,4'-diaminodiphenylmethane 3.887505956
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 2.5720471113
MESH:D006333 Heart Failure pirinixic acid 2.4320558911
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.2515720958
MESH:D006505 Hepatitis 4,4'-diaminodiphenylmethane 3.356705139
MESH:D006529 Hepatomegaly fumonisin B1 13.5816221962
MESH:D006529 Hepatomegaly Phenobarbital 13.5816109766
MESH:D006529 Hepatomegaly pirinixic acid 13.5816221962 19176532 18467677 19772884
MESH:D006849 Hydrocephalus Valproic Acid 4.6917688650
MESH:D006930 Hyperalgesia Acetaminophen 2.5716870215
MESH:D006937 Hypercholesterolemia Dietary Fats 3.4421332399
MESH:D006943 Hyperglycemia pirinixic acid 3.0320558911
MESH:D006949 Hyperlipidemias Dietary Fats 3.4521332399
MESH:D006965 Hyperplasia 4,4'-diaminodiphenylmethane 3.7715034207
MESH:D006973 Hypertension Cyclosporine 2.0410903974
MESH:D046110 Hypertension, Pregnancy-Induced Hydralazine 4.4516612254
MESH:D007021 Hypospadias Ethinyl Estradiol 3.6416945680 16569931
MESH:D020244 Infarction, Middle Cerebral Artery Progesterone 4.2315869954
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.3012013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 2.3717937319
MESH:D007249 Inflammation Dietary Fats 4.9020412841
MESH:D007249 Inflammation Progesterone 4.9015869954
MESH:D007333 Insulin Resistance Dietary Fats 6.8818457598 11836018
MESH:D007333 Insulin Resistance pirinixic acid 6.8816306350
MESH:D007565 Jaundice 4,4'-diaminodiphenylmethane 4.858074119 9022650
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.2715604871
MESH:D007674 Kidney Diseases Acetaminophen 5.4712587719 15629191
MESH:D007674 Kidney Diseases Cyclosporine 5.478314463 10903974 18776723
MESH:D007680 Kidney Neoplasms 2,4-dinitrotoluene 16.5916705839
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 16.5916705839
MESH:D007680 Kidney Neoplasms 4,4'-diaminodiphenylmethane 16.596582329
MESH:D007680 Kidney Neoplasms Cyclosporine 16.5912371664
MESH:D015470 Leukemia, Myeloid, Acute Valproic Acid 2.1216294345 17596541
MESH:D008103 Liver Cirrhosis Dietary Fats 6.3518296743
MESH:D008103 Liver Cirrhosis Phenobarbital 6.3521047994
MESH:D008105 Liver Cirrhosis, Biliary 4,4'-diaminodiphenylmethane 3.0915034207 9327722
MESH:D008106 Liver Cirrhosis, Experimental Fenofibrate 2.6515474484
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 2.6515474484
MESH:D008107 Liver Diseases Acetaminophen 3.7812587719 12969438 19784758 19014921 11587558 16611625 16610002 19460945
MESH:D008107 Liver Diseases Phenobarbital 3.7819363144
MESH:D017114 Liver Failure, Acute Acetaminophen 3.0816871587 17185352
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 17.147678174
MESH:D008113 Liver Neoplasms Aflatoxin B1 17.142125692 18177683 9163691 15890375
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 17.1421137059 20195826
MESH:D008113 Liver Neoplasms Fenofibrate 17.1418978307
MESH:D008113 Liver Neoplasms Phenobarbital 17.148742319 19812893 19482888 21047994 15975961 19073162
MESH:D008113 Liver Neoplasms pirinixic acid 17.1420007298 16377806 15890375
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 22.002876786 2876784 6135515
MESH:D008114 Liver Neoplasms, Experimental 4,4'-diaminodiphenylmethane 22.003712494 1399818 598648 6587162
MESH:D008114 Liver Neoplasms, Experimental Aflatoxin B1 22.008603461
MESH:D008114 Liver Neoplasms, Experimental Fenofibrate 22.0018253720 18775883
MESH:D008114 Liver Neoplasms, Experimental Methylcholanthrene 22.00598648 1399818
MESH:D008114 Liver Neoplasms, Experimental Phenobarbital 22.0017172636 2563599 6150874 1399818 18308698
MESH:D017563 Lung Diseases, Interstitial Valproic Acid 4.0917228818
MESH:D008175 Lung Neoplasms Aflatoxin B1 3.4114755239
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 3.4120869020 20464547 20135361 17053015 20064080 18816296 18569708 18520028 6695378
MESH:D008175 Lung Neoplasms Methylcholanthrene 3.4116271038 16337739 15390079 11893704 20970405 20512841 1399818 21163286 6695378 7750092 17909032 10545420 9230183
MESH:D008325 Mammary Neoplasms, Experimental Progesterone 2.7611408345 17203775
MESH:D008546 Melanoma, Experimental Acetaminophen 3.4019513568
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.6216801185
MESH:D008881 Migraine Disorders Valproic Acid 3.0718765137 18803445
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 3.0616381670
MESH:D009135 Muscular Diseases pirinixic acid 3.3416239165
MESH:D009139 Musculoskeletal Abnormalities Valproic Acid 3.878888407
MESH:D009190 Myelodysplastic Syndromes Valproic Acid 3.0617596541
MESH:D009203 Myocardial Infarction pirinixic acid 2.0719151258
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 2.8116411023
MESH:D020191 Myoclonic Epilepsies, Progressive Phenobarbital 4.3017484760
MESH:D009336 Necrosis 2,4-dinitrotoluene 9.7718551238
MESH:D009336 Necrosis 2,6-dinitrotoluene 9.777678174 18551238
MESH:D009362 Neoplasm Metastasis 4,4'-diaminodiphenylmethane 2.403581430
MESH:D009369 Neoplasms Benzo(a)pyrene 4.5411141357
MESH:D009369 Neoplasms pirinixic acid 4.5417405874
MESH:D009395 Nephritis, Interstitial Tetracycline 4.619884423
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.2717954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.1419348381 18481113
MESH:D009436 Neural Tube Defects 4,4'-diaminodiphenylmethane 6.896679447
MESH:D009436 Neural Tube Defects Valproic Acid 6.8916359493 8888407
MESH:D019636 Neurodegenerative Diseases Acetaminophen 2.7318514411
MESH:D009765 Obesity Dietary Fats 4.2918674790 20132043 18457598 17217161 16723640 11836018 20518802 21332399 19632207
MESH:D009765 Obesity pirinixic acid 4.2920558911
MESH:D009784 Occupational Diseases 2,4-dinitrotoluene 14.1916049721 12819281
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 14.1916049721
MESH:D009784 Occupational Diseases 4,4'-diaminodiphenylmethane 14.194026338 6482804
MESH:D009902 Optic Neuritis 4,4'-diaminodiphenylmethane 4.853988306
MESH:D010018 Osteomalacia Phenobarbital 4.1917016548
MESH:D010051 Ovarian Neoplasms Progesterone 2.4717393432 16525653
MESH:D010146 Pain Acetaminophen 2.2516870215
MESH:D010190 Pancreatic Neoplasms Phenobarbital 2.4316965848
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.5311578682
MESH:D010212 Papilloma 4,4'-diaminodiphenylmethane 3.317296757
MESH:D010391 Pemphigoid, Bullous Tetracycline 5.2611026799
MESH:D010787 Photosensitivity Disorders 4,4'-diaminodiphenylmethane 4.306228378
MESH:D011230 Precancerous Conditions Cyclosporine 8.4912371664
MESH:D011230 Precancerous Conditions Phenobarbital 8.492563599
MESH:D011297 Prenatal Exposure Delayed Effects Valproic Acid 3.6620603192
MESH:D017096 Prion Diseases Tetracycline 5.2410903871
MESH:D011471 Prostatic Neoplasms AGN 194204 3.6116000583
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 3.6117292933
MESH:D011537 Pruritus Ethinyl Estradiol 3.1416919318 15861022
MESH:D019310 Pseudolymphoma Phenobarbital 11.6112752131
MESH:D019310 Pseudolymphoma Valproic Acid 11.6111422049 12752131
MESH:D011565 Psoriasis Cyclosporine 2.1716882103
MESH:D015427 Reperfusion Injury pirinixic acid 2.3019058328
MESH:D012162 Retinal Degeneration 4,4'-diaminodiphenylmethane 3.253692021
MESH:D012208 Rhabdomyosarcoma Valproic Acid 4.0119155313
MESH:D012468 Salivary Gland Neoplasms Progesterone 2.8018045962
MESH:D012559 Schizophrenia Valproic Acid 2.0515737665 19110320
MESH:D012640 Seizures 2,4-dinitrotoluene 13.1218551238
MESH:D012640 Seizures 2,6-dinitrotoluene 13.1218551238
MESH:D012640 Seizures Phenobarbital 13.123137016 4039156 11442880 16876388
MESH:D012640 Seizures Valproic Acid 13.121511512 17978042 14763951 11738929 11044598 16876388 3137016 15475178
MESH:D003294 Seizures, Febrile Phenobarbital 4.656407741
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 2.2910029692 19755658
MESH:D013088 Spermatocele Ethinyl Estradiol 3.7716709447
MESH:D013119 Spinal Cord Injuries Progesterone 4.1115862959 16503802
MESH:D016135 Spinal Dysraphism Valproic Acid 3.6519490988
MESH:D013226 Status Epilepticus Valproic Acid 4.3712833885
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 1.552093021 20155912
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.4611994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.0115669648
MESH:D013964 Thyroid Neoplasms 4,4'-diaminodiphenylmethane 6.716582329 7505956 3712494 1399818 6587162
MESH:D013964 Thyroid Neoplasms Phenobarbital 6.711399818
MESH:D014178 Translocation, Genetic Valproic Acid 5.0617262798
MESH:D020194 Unverricht-Lundborg Syndrome Valproic Acid 4.353119515
MESH:D001749 Urinary Bladder Neoplasms 2,4-dinitrotoluene 11.3516049721
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 11.3516049721
MESH:D001749 Urinary Bladder Neoplasms 4,4'-diaminodiphenylmethane 11.358074119
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 11.3517053015
MESH:D014564 Urogenital Abnormalities Valproic Acid 4.478888407
MESH:D014571 Urologic Neoplasms 2,4-dinitrotoluene 11.4110091137
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 11.4110091137
MESH:D014581 Urticaria Acetaminophen 2.8210982225
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 3.1314692618
MESH:D014605 Uveitis Cyclosporine 3.811336536
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.3815869587 14671159
MESH:D015430 Weight Gain Dietary Fats 3.5916723640
MESH:D014985 Xerophthalmia Cyclosporine 4.2717120751
Pathway ID Pathway Name
KEGG:01100 Metabolic pathways
REACT:22258 Metabolism of lipids and lipoproteins
KEGG:00100 Steroid biosynthesis
Pharmacogenomics Knowledge Base Top
Drug Bank Top
Drugbank ID Action Drug Name Description
DB00157 - NADH Dietary supplement;Micronutrient
No data
No data
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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