Annotation Detail for TAS2R10
Basic Information Top
| Gene Symbol: | TAS2R10 ( MGC126811,MGC126813,T2R10,TRB2 ) |
|---|---|
| Gene Full Name: | taste receptor, type 2, member 10 |
| Band: | 12p13.2 |
| Quick Links | Entrez ID:50839; OMIM: 604791; Uniprot ID:T2R10_HUMAN; ENSEMBL ID: ENSG00000121318; HGNC ID: 14918 |
| Relate to Another Database: | SFARIGene; denovo-db |
Related Diseases/Disorders| Chemical ID | Chemical Name | Interaction | Interaction Action | Publication |
|---|---|---|---|---|
| D000638 | Amiodarone | Amiodarone results in increased expression of TAS2R10 mRNA | increases expression | 19774075 |
| C030691 | gluconic acid | gluconic acid results in decreased expression of TAS2R10 mRNA | decreases expression | 16556975 |
| Disease ID | Disease Name | Direct Evidence | Inference Chemical Name | Inference Score | Publication |
|---|---|---|---|---|---|
| MESH:D001145 | Arrhythmias, Cardiac | Amiodarone | 4.31 | 18218290 18057881 20041841 | |
| MESH:D001281 | Atrial Fibrillation | Amiodarone | 4.27 | 19698954 18651412 | |
| MESH:D001778 | Blood Coagulation Disorders | Amiodarone | 4.45 | 19483382 | |
| MESH:D002311 | Cardiomyopathy, Dilated | Amiodarone | 3.02 | 19225199 15710769 | |
| MESH:D002341 | Carotid Artery Thrombosis | Amiodarone | 5.97 | 18974383 | |
| MESH:D056486 | Drug-Induced Liver Injury | Amiodarone | 2.49 | 15265979 18218290 | |
| MESH:D005234 | Fatty Liver | Amiodarone | 4.07 | 14986274 | |
| MESH:D006529 | Hepatomegaly | Amiodarone | 4.51 | 15265979 | |
| MESH:D006937 | Hypercholesterolemia | Amiodarone | 4.42 | 8137927 9751232 | |
| MESH:D007037 | Hypothyroidism | Amiodarone | 5.28 | 18020914 17991464 | |
| MESH:D008064 | Lipidoses | Amiodarone | 3.85 | 17567588 15342952 | |
| MESH:D008133 | Long QT Syndrome | Amiodarone | 3.96 | 11989578 15350150 17391786 | |
| MESH:D008171 | Lung Diseases | Amiodarone | 3.68 | 12587719 | |
| MESH:D017563 | Lung Diseases, Interstitial | Amiodarone | 5.55 | 18516814 | |
| MESH:D009181 | Mycoses | Amiodarone | 5.97 | 12754197 17974566 | |
| MESH:D011658 | Pulmonary Fibrosis | Amiodarone | 2.99 | 11597910 12490602 12832656 | |
| OMIM:609620 | SHORT QT SYNDROME 1 | Amiodarone | 5.97 | 18724381 | |
| MESH:D013276 | Stomach Ulcer | Amiodarone | 3.86 | 18087811 | |
| MESH:D013610 | Tachycardia | Amiodarone | 4.96 | 11238279 | |
| MESH:D017180 | Tachycardia, Ventricular | Amiodarone | 4.86 | 19225199 | |
| MESH:D013959 | Thyroid Diseases | Amiodarone | 5.83 | 19731979 | |
| MESH:D013971 | Thyrotoxicosis | Amiodarone | 5.62 | 18020914 19584973 | |
| MESH:D016171 | Torsades de Pointes | Amiodarone | 5.08 | 11989578 17467628 |
| Pathway ID | Pathway Name |
|---|---|
| KEGG:04742 | Taste transduction |