AutismKB 2.0

Annotation Detail for PDE11A


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:PDE11A ( FLJ23693,MGC133355,MGC133356,PPNAD2 )
Gene Full Name: phosphodiesterase 11A
Band: 2q31.2
Quick LinksEntrez ID:50940; OMIM: 604961; Uniprot ID:PDE11_HUMAN; ENSEMBL ID: ENSG00000128655; HGNC ID: 8773
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa00230Purine metabolism
Pathway IDPathway Name
Signaling by GPCR
Hemostasis
No data
No data
No data
Related Diseases/Disorders Top
No data
No data
Desease Name
PHARMACOGENOMIC
depressive disorder, major
No data
Desease Name
Pigmented nodular adrenocortical disease, primary, 2
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000643 Ammonium Chloride Ammonium Chloride affects the expression of PDE11A mRNAaffects expression 16483693
D003976 Diazinon Diazinon results in increased expression of PDE11A mRNAincreases expression 17452286
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000138 Acidosis Ammonium Chloride 4.4418287403
MESH:D000382 Agricultural Workers' Diseases Diazinon 5.2216487989
MESH:D004417 Dyspnea Diazinon 5.8716487989
MESH:D006505 Hepatitis Diazinon 5.2516487989
MESH:D007248 Infertility, Male Diazinon 4.1316466525 12948887
OMIM:610475 PIGMENTED NODULAR ADRENOCORTICAL DISEASE, PRIMARY, 2 marker/mechanism
MESH:D011041 Poisoning Diazinon 4.9517603234
MESH:D014570 Urologic Diseases Diazinon 6.3516487989
Pathway ID Pathway Name
REACT:604 Hemostasis
KEGG:00230 Purine metabolism
REACT:14797 Signaling by GPCR
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA33121
    • No data
    Releated disease ID Related disease Name
    PA447278Depression
    PA447207Depressive Disorder
    PA447321Depressive Disorder, Major
    PA444544Hyperplasia
    Releated drug ID Related drug Name
    PA449673fluoxetine
    Drug Bank Top
    Drugbank ID Action Drug Name Description
    DB00820 inhibitor Tadalafil Vasodilator Agents;Phosphodiesterase Inhibitors
    No data
    No data
    No data

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


    Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved