AutismKB 2.0

Annotation Detail for PCCB


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Basic Information Top
Gene Symbol:PCCB ( DKFZp451E113 )
Gene Full Name: propionyl CoA carboxylase, beta polypeptide
Band: 3q22.3
Quick LinksEntrez ID:5096; OMIM: 232050; Uniprot ID:PCCB_HUMAN; ENSEMBL ID: ENSG00000114054; HGNC ID: 8654
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Pathway IDPathway Name
PROPIONMET-PWYmethylmalonyl pathway
PWY-5328superpathway of methionine degradation
PWY-51302-oxobutanoate degradation I
Pathway IDPathway Name
hsa00280Valine, leucine and isoleucine degradation
hsa00640Propanoate metabolism
hsa01100Metabolic pathways
Pathway IDPathway Name
Metabolism of lipids and lipoproteins
No data
Pathway IDPathway Name
P02777Succinate to proprionate conversion
P02755Methylmalonyl pathway
No data
Related Diseases/Disorders Top
Desease IDDesease Name
H00175Propionic acidemia
Inherited disorders of amino acid metabolism
Genetic disorders
No data
Desease Name
HEMATOLOGICAL
fibrinogen
Desease Name
Fibrinogen
Desease Name
Propionicacidemia
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C016403 2,4-dinitrotoluene 2,4-dinitrotoluene affects the expression of PCCB mRNAaffects expression 21346803
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene affects the expression of PCCB mRNAaffects expression 21346803
D016604 Aflatoxin B1 Aflatoxin B1 affects the expression of PCCB proteinaffects expression 20106945
D000638 Amiodarone Amiodarone affects the expression of PCCB mRNAaffects expression 19483382
D000643 Ammonium Chloride Ammonium Chloride affects the expression of PCCB mRNAaffects expression 16483693
D001553 Benzbromarone Benzbromarone affects the expression of PCCB mRNAaffects expression 19483382
D002994 Clofibrate Clofibrate affects the expression of PCCB mRNAaffects expression 19483382
D016572 Cyclosporine Cyclosporine results in decreased expression of PCCB mRNAdecreases expression 20106945
D004054 Diethylstilbestrol Diethylstilbestrol results in increased expression of PCCB mRNAincreases expression 14648872
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of PCCB mRNAincreases expression 17942748
D004997 Ethinyl Estradiol [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of PCCB mRNAaffects cotreatment|increases expression 17942748
D005001 Ethionine Ethionine affects the expression of PCCB mRNAaffects expression 19483382
D006830 Hydralazine [Hydralazine co-treated with Valproic Acid] results in increased expression of PCCB mRNAaffects cotreatment|increases expression 17183730
D009853 Omeprazole Omeprazole affects the expression of PCCB mRNAaffects expression 19483382
D017239 Paclitaxel Paclitaxel results in increased expression of PCCB mRNAincreases expression 15585946
C006253 pirinixic acid pirinixic acid affects the expression of PCCB mRNAaffects expression 19483382
C443641 poly(propyleneimine) poly(propyleneimine) analog results in decreased expression of PCCB mRNAdecreases expression 16308212
D011441 Propylthiouracil Propylthiouracil affects the expression of PCCB mRNAaffects expression 19483382
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of PCCB mRNAaffects cotreatment|increases expression 17942748
D013853 Thioacetamide Thioacetamide affects the expression of PCCB mRNAaffects expression 19483382
D014635 Valproic Acid [Hydralazine co-treated with Valproic Acid] results in increased expression of PCCB mRNAaffects cotreatment|increases expression 17183730
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 8.0315322242 14514962 11752688
MESH:D000014 Abnormalities, Drug-Induced Valproic Acid 8.038875741
MESH:D000015 Abnormalities, Multiple Valproic Acid 3.8419490988
MESH:D000138 Acidosis Ammonium Chloride 3.4718287403
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.8617505938
MESH:D055371 Acute Lung Injury pirinixic acid 3.0318653653
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 1.7914692618
MESH:D018248 Adenoma, Liver Cell pirinixic acid 9.6216434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 9.6216835633
MESH:D000550 Amblyopia Valproic Acid 5.1517688650
MESH:D000686 Amyloidosis Diethylstilbestrol 4.3915469931
MESH:D000740 Anemia Tetrachlorodibenzodioxin 2.8711748828
MESH:D001008 Anxiety Disorders Valproic Acid 3.5017497229
MESH:D001145 Arrhythmias, Cardiac Amiodarone 3.7218057881 18218290 20041841
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 3.3811256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 2.6115885639
MESH:D001281 Atrial Fibrillation Amiodarone 3.8419698954 18651412
MESH:D001321 Autistic Disorder Valproic Acid 2.0118940202 18985861 19232924 18775368 17688650 17507914 17157402 18558336 18396377 20603192 19460635 18177632 16609825 18316065 15238991
MESH:D001714 Bipolar Disorder Valproic Acid 3.0320046352 17594078
MESH:D001778 Blood Coagulation Disorders Amiodarone 56.9219483382
MESH:D001778 Blood Coagulation Disorders Benzbromarone 56.9219483382
MESH:D001778 Blood Coagulation Disorders Clofibrate 56.9219483382
MESH:D001778 Blood Coagulation Disorders Ethionine 56.9219483382
MESH:D001778 Blood Coagulation Disorders Omeprazole 56.9219483382
MESH:D001778 Blood Coagulation Disorders pirinixic acid 56.9219483382
MESH:D001778 Blood Coagulation Disorders Propylthiouracil 56.9219483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 56.9212125929
MESH:D001778 Blood Coagulation Disorders Thioacetamide 56.9219483382
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.7115340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 7.8315746008
MESH:D001848 Bone Diseases, Developmental Valproic Acid 7.838888407
MESH:D001859 Bone Neoplasms Paclitaxel 4.4815867366
MESH:D001943 Breast Neoplasms Diethylstilbestrol 1.9717129689 15324884
MESH:D001943 Breast Neoplasms Paclitaxel 1.9718323546 11325840 18234424 15136595 18223236 16273361 16115903 16244791
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 1.9720435547
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.7316835633
MESH:D006528 Carcinoma, Hepatocellular 2,4-dinitrotoluene 13.8916705839
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 13.8916705839
MESH:D006528 Carcinoma, Hepatocellular Aflatoxin B1 13.8912619106 21507988 12907637
MESH:D006528 Carcinoma, Hepatocellular Benzbromarone 13.891701930
MESH:D006528 Carcinoma, Hepatocellular Diethylstilbestrol 13.8915948411 16924424
MESH:D006528 Carcinoma, Hepatocellular Paclitaxel 13.8916313753
MESH:D006528 Carcinoma, Hepatocellular Thioacetamide 13.8917997003
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.3216120746 18850075 18670907
MESH:D002311 Cardiomyopathy, Dilated Amiodarone 2.8619225199 15710769
MESH:D002341 Carotid Artery Thrombosis Amiodarone 5.0018974383
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 10.896135515
MESH:D002471 Cell Transformation, Neoplastic Clofibrate 10.891399818
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 10.8912371664
MESH:D002637 Chest Pain Omeprazole 5.0315447763
MESH:D002659 Child Development Disorders, Pervasive Valproic Acid 2.6820734317
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 9.2916835633
MESH:D018281 Cholangiocarcinoma Thioacetamide 9.2918291259
MESH:D002779 Cholestasis Cyclosporine 12.9619486331
MESH:D002779 Cholestasis Ethinyl Estradiol 12.9617333356 11677210 17110522 16105132 15861022 17681005 16919318
MESH:D002779 Cholestasis pirinixic acid 12.9619176532
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 2.0712621046 15340226 15668235 8697196 16354765
MESH:D015179 Colorectal Neoplasms Paclitaxel 2.4418802399
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 2.9817141729 14669216
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 2.4520055451 10048152 15322242
MESH:D019465 Craniofacial Abnormalities Valproic Acid 2.4516575769 17688650 8888407
MESH:D003456 Cryptorchidism Diethylstilbestrol 4.4712952375 16002989
MESH:D003490 Cyanosis 2,4-dinitrotoluene 10.6018551238
MESH:D003490 Cyanosis 2,6-dinitrotoluene 10.6018551238
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.3818249437
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 1.6517107852
MESH:D056486 Drug-Induced Liver Injury 2,4-dinitrotoluene 14.9318551238 21346803
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 14.9318551238 21346803
MESH:D056486 Drug-Induced Liver Injury Amiodarone 14.9318218290 15265979
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 14.9320420201
MESH:D056486 Drug-Induced Liver Injury Thioacetamide 14.9312963478
MESH:D056486 Drug-Induced Liver Injury Valproic Acid 14.9319641884 1733752
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.6911462148
MESH:D004381 Duodenal Ulcer Omeprazole 4.2415991576 17151854 16613094 21218061
MESH:D050171 Dyslipidemias Clofibrate 4.0016707586
MESH:D004421 Dystonia Valproic Acid 3.961851702
MESH:D004487 Edema pirinixic acid 6.2712083418
MESH:D004487 Edema Tetrachlorodibenzodioxin 6.2712711302 11000095
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 3.8216714409 15322242 18230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 3.1012538720
MESH:D004714 Endometrial Hyperplasia Diethylstilbestrol 4.6116402032
MESH:D016889 Endometrial Neoplasms Diethylstilbestrol 3.4115700306 16804899
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 2.949294722 10568697
MESH:D004831 Epilepsies, Myoclonic Valproic Acid 4.073659116 17275665
MESH:D004828 Epilepsies, Partial Valproic Acid 3.8416628512 3922381
MESH:D004827 Epilepsy Valproic Acid 2.8918234410 20417680
MESH:D004832 Epilepsy, Absence Valproic Acid 3.516426943 6254150 7562514
MESH:D017029 Epilepsy, Complex Partial Valproic Acid 4.217750514
MESH:D004830 Epilepsy, Tonic-Clonic Valproic Acid 3.983659116
MESH:D004938 Esophageal Neoplasms Paclitaxel 2.8716481741
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 2.9511564622
MESH:D005218 Fat Necrosis Thioacetamide 5.6416456712
MESH:D005234 Fatty Liver Amiodarone 29.6714986274
MESH:D005234 Fatty Liver Clofibrate 29.6719224547
MESH:D005234 Fatty Liver Cyclosporine 29.6719224547
MESH:D005234 Fatty Liver Ethinyl Estradiol 29.6715345470
MESH:D005234 Fatty Liver pirinixic acid 29.6720131406 19236843
MESH:D005234 Fatty Liver Valproic Acid 29.6714986274 19224547
MESH:D052776 Female Urogenital Diseases Diethylstilbestrol 3.6016002989 16513791 15751030 16611131 16534752
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.3711858732
MESH:D005315 Fetal Diseases Valproic Acid 4.8116575769
MESH:D005317 Fetal Growth Retardation Valproic Acid 4.048888407 18558336
MESH:D005355 Fibrosis Cyclosporine 8.1912168785 12639820
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 8.1920067830
MESH:D005833 Genital Neoplasms, Female Diethylstilbestrol 4.8616452187
MESH:D005885 Gingival Hyperplasia Cyclosporine 4.138708960
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.5110696789
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 2.2811294989 10048152
MESH:D006333 Heart Failure pirinixic acid 2.4820558911
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.3415720958
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.2511000095
MESH:D006501 Hepatic Encephalopathy Thioacetamide 4.4918665440 17276928 15929193
MESH:D006505 Hepatitis Thioacetamide 4.1316456712
MESH:D006529 Hepatomegaly Amiodarone 13.9215265979
MESH:D006529 Hepatomegaly pirinixic acid 13.9219176532 19772884 18467677 16221962
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 13.9216120746 15340226 12621046
MESH:D006849 Hydrocephalus Valproic Acid 4.7817688650
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.9615340226 8697196 18606429 16354765 16959395
MESH:D006937 Hypercholesterolemia Amiodarone 3.798137927 9751232
MESH:D006943 Hyperglycemia pirinixic acid 3.1020558911
MESH:D006965 Hyperplasia Diethylstilbestrol 4.3514722030 12960047
MESH:D006973 Hypertension Cyclosporine 4.8310903974
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 4.8318670907 18850075
MESH:D046110 Hypertension, Pregnancy-Induced Hydralazine 4.5416612254
MESH:D007021 Hypospadias Diethylstilbestrol 10.9516002989
MESH:D007021 Hypospadias Ethinyl Estradiol 10.9516945680 16569931
MESH:D007037 Hypothyroidism Amiodarone 11.3217991464 18020914
MESH:D007037 Hypothyroidism Propylthiouracil 11.3218031379 8137927
MESH:D007246 Infertility Diethylstilbestrol 4.2715036965
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.3812013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 2.4317937319
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 1.8112878042 12200463
MESH:D007333 Insulin Resistance pirinixic acid 2.5716306350
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 3.2516580747
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.3615604871
MESH:D007674 Kidney Diseases Cyclosporine 2.2918776723 10903974 8314463
MESH:D007680 Kidney Neoplasms 2,4-dinitrotoluene 17.1616705839
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 17.1616705839
MESH:D007680 Kidney Neoplasms Cyclosporine 17.1612371664
MESH:D007680 Kidney Neoplasms Diethylstilbestrol 17.1615003126 14681315 16762066
MESH:D007859 Learning Disorders Diethylstilbestrol 3.9717184923
MESH:D016773 Leishmaniasis, Cutaneous Omeprazole 4.0219248655
MESH:D015470 Leukemia, Myeloid, Acute Valproic Acid 2.1416294345 17596541
MESH:D008064 Lipidoses Amiodarone 3.4517567588 15342952
MESH:D008080 Liposarcoma Paclitaxel 4.7417353645
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 3.4115474484
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 3.4112878042
MESH:D008106 Liver Cirrhosis, Experimental Thioacetamide 3.4112557150 18458672 15288472 18395095 10677585 17629604 15288473 17355460 12175628 11481614 15334695 16126171 16489207 15474484 17050028 15316131 16343077 11172339 16097051 16248980 15362042 15158331 14739098 12531686 18263696 18031379 12891558 15716488 17127702 18032466 12679928 11682029 16098781 15078482 18615449 18380797 12085344 18416461 15465738 15075984 17292413 18295389 16511523 15095483 18606216
MESH:D008107 Liver Diseases Thioacetamide 2.6816337175 18374380 15158337
MESH:D017114 Liver Failure, Acute Thioacetamide 4.2315633222 12479984 17276928 15313186
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 13.887678174
MESH:D008113 Liver Neoplasms Aflatoxin B1 13.882125692 18177683 9163691 15890375
MESH:D008113 Liver Neoplasms Diethylstilbestrol 13.8815890375 16712894
MESH:D008113 Liver Neoplasms pirinixic acid 13.8816377806 20007298 15890375
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 13.8816984957
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 9.482876784 6135515 2876786
MESH:D008114 Liver Neoplasms, Experimental Aflatoxin B1 9.488603461
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 9.4812151625
MESH:D008133 Long QT Syndrome Amiodarone 3.5117391786 15350150 11989578
MESH:D008171 Lung Diseases Amiodarone 3.3112587719
MESH:D017563 Lung Diseases, Interstitial Amiodarone 10.9918516814
MESH:D017563 Lung Diseases, Interstitial Valproic Acid 10.9917228818
MESH:D008175 Lung Neoplasms Aflatoxin B1 2.2714755239
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 2.2711884234 19555203
MESH:D008181 Lupus Nephritis Diethylstilbestrol 5.0615166399
MESH:D008223 Lymphoma Diethylstilbestrol 3.4115700306
MESH:D008228 Lymphoma, Non-Hodgkin Paclitaxel 4.0214749477
MESH:D052801 Male Urogenital Diseases Diethylstilbestrol 5.4316002989
MESH:D008545 Melanoma Paclitaxel 2.5816342250 12025231 12040289
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.7116801185
MESH:D008881 Migraine Disorders Valproic Acid 3.1318765137 18803445
MESH:D009101 Multiple Myeloma Paclitaxel 3.6214749477
MESH:D009135 Muscular Diseases pirinixic acid 3.4216239165
MESH:D009139 Musculoskeletal Abnormalities Valproic Acid 3.948888407
MESH:D009181 Mycoses Amiodarone 4.8212754197 17974566
MESH:D009190 Myelodysplastic Syndromes Valproic Acid 3.1017596541
MESH:D009203 Myocardial Infarction pirinixic acid 2.1119151258
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 2.9512213967
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 2.8816411023
MESH:D009336 Necrosis 2,4-dinitrotoluene 10.0618551238
MESH:D009336 Necrosis 2,6-dinitrotoluene 10.067678174 18551238
MESH:D009362 Neoplasm Metastasis Paclitaxel 3.2215867366
MESH:D009369 Neoplasms Diethylstilbestrol 4.9015313581
MESH:D009369 Neoplasms pirinixic acid 4.9017405874
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.3617954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.2119348381 18481113
MESH:D009421 Nervous System Malformations Diethylstilbestrol 9.3611399458
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 9.3614600291
MESH:D009436 Neural Tube Defects Valproic Acid 3.078888407 16359493
MESH:D052556 Niemann-Pick Disease, Type C Clofibrate 4.859802331
MESH:D009765 Obesity pirinixic acid 1.7920558911
MESH:D009784 Occupational Diseases 2,4-dinitrotoluene 8.6216049721 12819281
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 8.6216049721
MESH:D010014 Osteolysis Paclitaxel 4.8915867366
MESH:D010051 Ovarian Neoplasms Paclitaxel 2.9611161223
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.6011578682
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.1712520081
MESH:D010900 Pituitary Diseases Diethylstilbestrol 5.0914722030
MESH:D010911 Pituitary Neoplasms Diethylstilbestrol 4.5816977796 15687265
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.4718163543
MESH:D011230 Precancerous Conditions Cyclosporine 3.1412371664
MESH:D011297 Prenatal Exposure Delayed Effects Diethylstilbestrol 15.7717184923
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 15.7711399792 11222880 11118676 11896295
MESH:D011297 Prenatal Exposure Delayed Effects Valproic Acid 15.7720603192
MESH:D056693 Propionic Acidemia marker/mechanism
MESH:D011471 Prostatic Neoplasms Diethylstilbestrol 3.6417136230 15046698 15846301
MESH:D011471 Prostatic Neoplasms Paclitaxel 3.6416729912 17136230 17172428 16356831
MESH:D011537 Pruritus Ethinyl Estradiol 3.2315861022 16919318
MESH:D019310 Pseudolymphoma Valproic Acid 4.4612752131 11422049
MESH:D011565 Psoriasis Cyclosporine 2.2016882103
MESH:D011658 Pulmonary Fibrosis Amiodarone 2.8212832656 11597910 12490602
MESH:D015427 Reperfusion Injury pirinixic acid 2.3419058328
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.7518990726
MESH:D012208 Rhabdomyosarcoma Valproic Acid 4.0919155313
MESH:D012559 Schizophrenia Valproic Acid 2.0615737665 19110320
MESH:D012640 Seizures 2,4-dinitrotoluene 9.4618551238
MESH:D012640 Seizures 2,6-dinitrotoluene 9.4618551238
MESH:D012640 Seizures Valproic Acid 9.461511512 11738929 14763951 3137016 16876388 17978042 15475178 11044598
OMIM:609620 SHORT QT SYNDROME 1 Amiodarone 5.0018724381
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 2.0016192470
MESH:D013088 Spermatocele Diethylstilbestrol 11.4416002989 16709447
MESH:D013088 Spermatocele Ethinyl Estradiol 11.4416709447
MESH:D016135 Spinal Dysraphism Valproic Acid 3.7119490988
MESH:D013226 Status Epilepticus Valproic Acid 4.4612833885
MESH:D013272 Stomach Diseases Omeprazole 4.5318545984
MESH:D013274 Stomach Neoplasms Paclitaxel 2.4418506536 18396642
MESH:D013276 Stomach Ulcer Amiodarone 7.3018087811
MESH:D013276 Stomach Ulcer Omeprazole 7.3018237397 11906479 10750652 15991576 16755016 17977527
MESH:D013610 Tachycardia Amiodarone 4.2011238279
MESH:D017180 Tachycardia, Ventricular Amiodarone 4.1019225199
MESH:D024801 Tauopathies Paclitaxel 4.7316930453
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.5411994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.0715669648
MESH:D013959 Thyroid Diseases Amiodarone 11.7819731979
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 11.7812697716
MESH:D013964 Thyroid Neoplasms Propylthiouracil 3.6115710170
MESH:D013971 Thyrotoxicosis Amiodarone 4.7718020914 19584973
MESH:D016171 Torsades de Pointes Amiodarone 4.1111989578 17467628
MESH:D014178 Translocation, Genetic Valproic Acid 5.1517262798
MESH:D020194 Unverricht-Lundborg Syndrome Valproic Acid 4.443119515
MESH:D001749 Urinary Bladder Neoplasms 2,4-dinitrotoluene 8.1516049721
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 8.1516049721
MESH:D001749 Urinary Bladder Neoplasms Diethylstilbestrol 8.1516452187 16712894 17306315
MESH:D014564 Urogenital Abnormalities Valproic Acid 4.568888407
MESH:D014571 Urologic Neoplasms 2,4-dinitrotoluene 11.7010091137
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 11.7010091137
MESH:D002583 Uterine Cervical Neoplasms Diethylstilbestrol 3.9516175088
MESH:D014591 Uterine Diseases Diethylstilbestrol 5.0914652134
MESH:D014594 Uterine Neoplasms Diethylstilbestrol 9.1915809267 16690809
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 9.1914692618
MESH:D014605 Uveitis Cyclosporine 3.901336536
MESH:D014625 Vaginal Neoplasms Diethylstilbestrol 4.3516513791 16002989
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.5112125929
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.4614671159 15869587
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.1715886252
MESH:D014985 Xerophthalmia Cyclosporine 4.3617120751
Pathway ID Pathway Name
KEGG:00630 Glyoxylate and dicarboxylate metabolism
KEGG:01100 Metabolic pathways
REACT:22258 Metabolism of lipids and lipoproteins
KEGG:00640 Propanoate metabolism
KEGG:00280 Valine, leucine and isoleucine degradation
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA32993
    • No data
    Releated disease ID Related disease Name
    PA162370426Propionic acidemia
    Releated drug ID Related drug Name
    PA448625biotin
    Drug Bank Top
    Drugbank ID Action Drug Name Description
    DB00121 - Biotin Dietary supplement;Micronutrient;Vitamins (Vitamin B Complex);Vitamin B Complex
    DB00161 - L-Valine Dietary supplements;Essential Amino Acids;Micronutrients
    No data
    No data
    No data

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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