Chemical ID |
Chemical Name |
Interaction |
Interaction Action |
Publication |
---|
C015001 |
arsenite |
arsenite results in increased expression of PCDH9 mRNA | increases expression | 18929588
|
C015001 |
arsenite |
TRP53 protein affects the reaction [arsenite results in increased expression of PCDH9 mRNA] | affects reaction|increases expression | 18929588
|
D017638 |
Asbestos, Crocidolite |
Asbestos, Crocidolite results in decreased expression of PCDH9 mRNA | decreases expression | 18687144
|
D015123 |
7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide |
7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased expression of PCDH9 mRNA | increases expression | 20382639
|
D020122 |
tert-Butylhydroperoxide |
tert-Butylhydroperoxide results in decreased expression of PCDH9 mRNA | decreases expression | 15336504
|
D016572 |
Cyclosporine |
Cyclosporine results in decreased expression of PCDH9 mRNA | decreases expression | 20106945
|
D004054 |
Diethylstilbestrol |
Diethylstilbestrol results in increased expression of PCDH9 mRNA | increases expression | 17005392
|
C006253 |
pirinixic acid |
[pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of PCDH9 mRNA | affects binding|decreases expression|increases activity | 19710929
|
D014415 |
Tunicamycin |
Tunicamycin results in increased expression of PCDH9 mRNA | increases expression | 17127020
|
Disease ID |
Disease Name |
Direct Evidence |
Inference Chemical Name |
Inference Score |
Publication |
---|
MESH:D055371 |
Acute Lung Injury |
|
pirinixic acid |
3.38 | 18653653 |
MESH:D018248 |
Adenoma, Liver Cell |
|
pirinixic acid |
3.82 | 16434500 |
MESH:D000686 |
Amyloidosis |
|
Diethylstilbestrol |
4.76 | 15469931 |
MESH:D001778 |
Blood Coagulation Disorders |
|
pirinixic acid |
3.39 | 19483382 |
MESH:D001943 |
Breast Neoplasms |
|
Diethylstilbestrol |
2.60 | 17129689 15324884 |
MESH:D006528 |
Carcinoma, Hepatocellular |
|
Diethylstilbestrol |
2.26 | 15948411 16924424 |
MESH:D002471 |
Cell Transformation, Neoplastic |
|
7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide |
7.09 | 20889678 |
MESH:D002471 |
Cell Transformation, Neoplastic |
|
Cyclosporine |
7.09 | 12371664 |
MESH:D002659 |
Child Development Disorders, Pervasive |
marker/mechanism |
|
| 18252227 |
MESH:D002779 |
Cholestasis |
|
Cyclosporine |
8.35 | 19486331 |
MESH:D002779 |
Cholestasis |
|
pirinixic acid |
8.35 | 19176532 |
MESH:D003110 |
Colonic Neoplasms |
|
arsenite |
2.62 | 15037631 |
MESH:D003456 |
Cryptorchidism |
|
Diethylstilbestrol |
4.84 | 16002989 12952375 |
MESH:D003876 |
Dermatitis, Atopic |
|
pirinixic acid |
2.52 | 18249437 |
MESH:D004487 |
Edema |
|
pirinixic acid |
2.72 | 12083418 |
MESH:D004714 |
Endometrial Hyperplasia |
|
Diethylstilbestrol |
5.03 | 16402032 |
MESH:D016889 |
Endometrial Neoplasms |
|
Diethylstilbestrol |
3.61 | 16804899 15700306 |
MESH:D004938 |
Esophageal Neoplasms |
|
7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide |
2.12 | 20426865 |
MESH:D005234 |
Fatty Liver |
|
arsenite |
14.59 | 18296743 |
MESH:D005234 |
Fatty Liver |
|
Cyclosporine |
14.59 | 19224547 |
MESH:D005234 |
Fatty Liver |
|
pirinixic acid |
14.59 | 19236843 20131406 |
MESH:D052776 |
Female Urogenital Diseases |
|
Diethylstilbestrol |
3.79 | 16534752 16513791 16611131 15751030 16002989 |
MESH:D005355 |
Fibrosis |
|
arsenite |
9.93 | 18296743 |
MESH:D005355 |
Fibrosis |
|
Cyclosporine |
9.93 | 12639820 12168785 |
MESH:D005833 |
Genital Neoplasms, Female |
|
Diethylstilbestrol |
5.28 | 16452187 |
MESH:D005885 |
Gingival Hyperplasia |
|
Cyclosporine |
4.56 | 8708960 |
MESH:D006333 |
Heart Failure |
|
pirinixic acid |
2.67 | 20558911 |
MESH:D006457 |
Hemoglobinuria, Paroxysmal |
|
Cyclosporine |
4.76 | 15720958 |
MESH:D006529 |
Hepatomegaly |
|
pirinixic acid |
3.30 | 16221962 19176532 18467677 19772884 |
MESH:D006943 |
Hyperglycemia |
|
pirinixic acid |
3.41 | 20558911 |
MESH:D006965 |
Hyperplasia |
|
Diethylstilbestrol |
4.74 | 14722030 12960047 |
MESH:D006973 |
Hypertension |
|
Cyclosporine |
2.17 | 10903974 |
MESH:D007021 |
Hypospadias |
|
Diethylstilbestrol |
4.89 | 16002989 |
MESH:D007246 |
Infertility |
|
Diethylstilbestrol |
4.64 | 15036965 |
MESH:D007333 |
Insulin Resistance |
|
pirinixic acid |
2.78 | 16306350 |
MESH:D007638 |
Keratoconjunctivitis Sicca |
|
Cyclosporine |
4.82 | 15604871 |
MESH:D007674 |
Kidney Diseases |
|
Cyclosporine |
2.46 | 8314463 18776723 10903974 |
MESH:D007680 |
Kidney Neoplasms |
|
Cyclosporine |
8.13 | 12371664 |
MESH:D007680 |
Kidney Neoplasms |
|
Diethylstilbestrol |
8.13 | 15003126 14681315 16762066 |
MESH:D007859 |
Learning Disorders |
|
Diethylstilbestrol |
4.37 | 17184923 |
MESH:D008103 |
Liver Cirrhosis |
|
arsenite |
3.54 | 18296743 |
MESH:D008106 |
Liver Cirrhosis, Experimental |
|
pirinixic acid |
1.35 | 15474484 |
MESH:D008113 |
Liver Neoplasms |
|
Diethylstilbestrol |
4.84 | 15890375 16712894 |
MESH:D008113 |
Liver Neoplasms |
|
pirinixic acid |
4.84 | 20007298 16377806 15890375 |
MESH:D055370 |
Lung Injury |
|
Asbestos, Crocidolite |
4.33 | 17365036 |
MESH:D008175 |
Lung Neoplasms |
|
arsenite |
2.36 | 16809336 |
MESH:D008181 |
Lupus Nephritis |
|
Diethylstilbestrol |
5.49 | 15166399 |
MESH:D008223 |
Lymphoma |
|
Diethylstilbestrol |
3.64 | 15700306 |
MESH:D052801 |
Male Urogenital Diseases |
|
Diethylstilbestrol |
5.89 | 16002989 |
MESH:D008654 |
Mesothelioma |
|
Asbestos, Crocidolite |
3.26 | 16166281 16966607 18303189 |
MESH:D008664 |
Metal Metabolism, Inborn Errors |
|
Cyclosporine |
5.16 | 16801185 |
MESH:D009135 |
Muscular Diseases |
|
pirinixic acid |
3.81 | 16239165 |
MESH:D009203 |
Myocardial Infarction |
|
pirinixic acid |
2.22 | 19151258 |
MESH:D015428 |
Myocardial Reperfusion Injury |
|
pirinixic acid |
3.13 | 16411023 |
MESH:D009369 |
Neoplasms |
|
Diethylstilbestrol |
5.39 | 15313581 |
MESH:D009369 |
Neoplasms |
|
pirinixic acid |
5.39 | 17405874 |
MESH:D009389 |
Neovascularization, Pathologic |
|
arsenite |
4.75 | 15738583 |
MESH:D009402 |
Nephrosis, Lipoid |
|
Cyclosporine |
4.82 | 17954296 |
MESH:D009404 |
Nephrotic Syndrome |
|
Cyclosporine |
3.50 | 19348381 18481113 |
MESH:D009421 |
Nervous System Malformations |
|
Diethylstilbestrol |
4.42 | 11399458 |
MESH:D009765 |
Obesity |
|
pirinixic acid |
1.86 | 20558911 |
MESH:D010900 |
Pituitary Diseases |
|
Diethylstilbestrol |
5.55 | 14722030 |
MESH:D010911 |
Pituitary Neoplasms |
|
Diethylstilbestrol |
4.98 | 15687265 16977796 |
MESH:D010995 |
Pleural Diseases |
|
Asbestos, Crocidolite |
5.20 | 10923243 |
MESH:D011230 |
Precancerous Conditions |
|
Cyclosporine |
3.44 | 12371664 |
MESH:D011297 |
Prenatal Exposure Delayed Effects |
|
Diethylstilbestrol |
4.45 | 17184923 |
MESH:D011471 |
Prostatic Neoplasms |
|
Diethylstilbestrol |
3.53 | 15046698 17136230 15846301 |
MESH:D011565 |
Psoriasis |
|
Cyclosporine |
2.30 | 16882103 |
MESH:D011658 |
Pulmonary Fibrosis |
|
Asbestos, Crocidolite |
3.10 | 15814490 17322281 17365031 17975199 |
MESH:D015427 |
Reperfusion Injury |
|
pirinixic acid |
2.49 | 19058328 |
MESH:D012878 |
Skin Neoplasms |
|
tert-Butylhydroperoxide |
2.79 | 8532709 |
MESH:D013088 |
Spermatocele |
|
Diethylstilbestrol |
5.09 | 16002989 16709447 |
MESH:D001749 |
Urinary Bladder Neoplasms |
|
Diethylstilbestrol |
2.85 | 17306315 16712894 16452187 |
MESH:D002583 |
Uterine Cervical Neoplasms |
|
Diethylstilbestrol |
4.26 | 16175088 |
MESH:D014591 |
Uterine Diseases |
|
Diethylstilbestrol |
5.55 | 14652134 |
MESH:D014594 |
Uterine Neoplasms |
|
Diethylstilbestrol |
4.35 | 15809267 16690809 |
MESH:D014605 |
Uveitis |
|
Cyclosporine |
4.36 | 1336536 |
MESH:D014625 |
Vaginal Neoplasms |
|
Diethylstilbestrol |
4.74 | 16513791 16002989 |
MESH:D014985 |
Xerophthalmia |
|
Cyclosporine |
4.82 | 17120751 |