AutismKB 2.0

Annotation Detail for GLOD4


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Basic Information Top
Gene Symbol:GLOD4 ( C17orf25,HC71 )
Gene Full Name: glyoxalase domain containing 4
Band: 17p13.3
Quick LinksEntrez ID:51031; OMIM: NA; Uniprot ID:GLOD4_HUMAN; ENSEMBL ID: ENSG00000167699; HGNC ID: 14111
Relate to Another Database: SFARIGene; denovo-db
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Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000082 Acetaminophen Acetaminophen affects the expression of GLOD4 mRNAaffects expression 17562736
D020122 tert-Butylhydroperoxide tert-Butylhydroperoxide results in increased expression of GLOD4 mRNAincreases expression 15003993
D015741 Metribolone Metribolone results in decreased expression of GLOD4 proteindecreases expression 17152098
D018038 Sodium Selenite Sodium Selenite results in increased expression of GLOD4 mRNAincreases expression 18175754
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000799 Angioedema Acetaminophen 4.5710982225
MESH:D001321 Autistic Disorder Acetaminophen 1.4018445737
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 1.413084413
MESH:D002386 Cataract Acetaminophen 2.7910977129
MESH:D019457 Chromosome Breakage Sodium Selenite 5.3115894690
MESH:D003920 Diabetes Mellitus Sodium Selenite 4.1516285004
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 4.1412958197 16393943 16081117 14550746 14986274 19420014 16109766 17562736 11834606 12392966 2444490 19370779 19923254 12153990 16227642 12594235 12705907 18713872 17906064 18071297 14725611 10774834 16781746 11461765 19085960 11739529 15968718 10663392 11287661 19416960 19739265 19164858 10915739 12540782 11421492 16485898 16177239 15619225 17522070 11529661 11743745
MESH:D056486 Drug-Induced Liver Injury Sodium Selenite 4.1415131321
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.8219426721
MESH:D005756 Gastritis Acetaminophen 4.4016983495
MESH:D006930 Hyperalgesia Acetaminophen 3.0216870215
MESH:D007333 Insulin Resistance Sodium Selenite 3.5214714311
MESH:D007674 Kidney Diseases Acetaminophen 2.4015629191 12587719
MESH:D008107 Liver Diseases Acetaminophen 1.7019460945 16611625 19784758 16610002 19014921 11587558 12969438 12587719
MESH:D017114 Liver Failure, Acute Acetaminophen 3.6317185352 16871587
MESH:D016393 Lymphoma, B-Cell Sodium Selenite 4.5214737004
MESH:D008546 Melanoma, Experimental Acetaminophen 4.1319513568
MESH:D019636 Neurodegenerative Diseases Acetaminophen 3.2118514411
MESH:D010146 Pain Acetaminophen 2.7316870215
MESH:D011471 Prostatic Neoplasms Sodium Selenite 3.3318760546
MESH:D012878 Skin Neoplasms tert-Butylhydroperoxide 2.848532709
MESH:D014581 Urticaria Acetaminophen 3.4410982225
No data
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Syndromic Genes

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AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018