Annotation Detail for DERA
Basic Information
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| Pathway ID | Pathway Name |
|---|
| hsa00030 | Pentose phosphate pathway |
| Chemical ID |
Chemical Name |
Interaction |
Interaction Action |
Publication |
|---|
| D000082 |
Acetaminophen |
Acetaminophen affects the expression of DERA mRNA | affects expression | 17562736
|
| C004541 |
biochanin A |
biochanin A results in decreased expression of DERA mRNA | decreases expression | 12111696
|
| D016572 |
Cyclosporine |
Cyclosporine results in decreased expression of DERA mRNA | decreases expression | 20106945
|
| D012643 |
Selenium |
Selenium results in decreased expression of DERA mRNA | decreases expression | 19244175
|
| D014747 |
Vinblastine |
DERA protein affects the susceptibility to Vinblastine | affects response to substance | 16217747
|
| Disease ID |
Disease Name |
Direct Evidence |
Inference Chemical Name |
Inference Score |
Publication |
|---|
| MESH:D000799 |
Angioedema |
|
Acetaminophen |
4.45 | 10982225 |
| MESH:D001321 |
Autistic Disorder |
|
Acetaminophen |
1.40 | 18445737 |
| MESH:D006528 |
Carcinoma, Hepatocellular |
|
Acetaminophen |
1.40 | 3084413 |
| MESH:D002292 |
Carcinoma, Renal Cell |
|
Vinblastine |
3.92 | 1485588 |
| MESH:D002386 |
Cataract |
|
Acetaminophen |
2.77 | 10977129 |
| MESH:D002471 |
Cell Transformation, Neoplastic |
|
Cyclosporine |
2.76 | 12371664 |
| MESH:D002779 |
Cholestasis |
|
Cyclosporine |
3.17 | 19486331 |
| MESH:D003092 |
Colitis |
|
Selenium |
4.26 | 17936198 |
| MESH:D015179 |
Colorectal Neoplasms |
|
Vinblastine |
2.77 | 18802399 |
| MESH:D056486 |
Drug-Induced Liver Injury |
|
Acetaminophen |
4.07 | 16081117 17562736 17522070 11529661 15968718 12594235 19085960 19420014 17906064 16485898 12958197 14986274 16781746 16227642 16177239 11743745 11421492 19370779 14725611 14550746 11461765 12392966 19416960 16393943 16109766 12153990 19739265 12540782 18071297 11834606 10915739 2444490 12705907 19923254 18713872 19164858 11287661 10663392 11739529 10774834 15619225 |
| MESH:D056486 |
Drug-Induced Liver Injury |
|
Selenium |
4.07 | 15131321 |
| MESH:D056487 |
Drug-Induced Liver Injury, Chronic |
|
Acetaminophen |
4.71 | 19426721 |
| MESH:D005234 |
Fatty Liver |
|
Cyclosporine |
3.23 | 19224547 |
| MESH:D005355 |
Fibrosis |
|
Cyclosporine |
3.62 | 12639820 12168785 |
| MESH:D005756 |
Gastritis |
|
Acetaminophen |
4.29 | 16983495 |
| MESH:D005885 |
Gingival Hyperplasia |
|
Cyclosporine |
4.76 | 8708960 |
| MESH:D005909 |
Glioblastoma |
|
biochanin A |
4.67 | 16598420 |
| MESH:D006333 |
Heart Failure |
|
Selenium |
3.27 | 17162251 |
| MESH:D006457 |
Hemoglobinuria, Paroxysmal |
|
Cyclosporine |
4.96 | 15720958 |
| MESH:D006689 |
Hodgkin Disease |
|
Vinblastine |
4.35 | 18180244 18501091 |
| MESH:D006930 |
Hyperalgesia |
|
Acetaminophen |
2.99 | 16870215 |
| MESH:D006973 |
Hypertension |
|
Cyclosporine |
2.20 | 10903974 |
| MESH:D007251 |
Influenza, Human |
|
Selenium |
4.81 | 16624496 |
| MESH:D007638 |
Keratoconjunctivitis Sicca |
|
Cyclosporine |
5.05 | 15604871 |
| MESH:D007674 |
Kidney Diseases |
|
Acetaminophen |
6.41 | 15629191 12587719 |
| MESH:D007674 |
Kidney Diseases |
|
Cyclosporine |
6.41 | 10903974 8314463 18776723 |
| MESH:D007676 |
Kidney Failure, Chronic |
|
Selenium |
4.26 | 16518626 |
| MESH:D007680 |
Kidney Neoplasms |
|
Cyclosporine |
3.04 | 12371664 |
| MESH:D008107 |
Liver Diseases |
|
Acetaminophen |
1.69 | 11587558 19014921 16610002 19784758 12587719 19460945 12969438 16611625 |
| MESH:D017114 |
Liver Failure, Acute |
|
Acetaminophen |
3.58 | 17185352 16871587 |
| MESH:D008325 |
Mammary Neoplasms, Experimental |
|
Selenium |
2.97 | 15318939 |
| MESH:D008545 |
Melanoma |
|
Vinblastine |
2.94 | 15577323 12374674 16248763 15577320 16432458 17761969 18505091 18332650 16809738 18176117 |
| MESH:D008546 |
Melanoma, Experimental |
|
Acetaminophen |
4.05 | 19513568 |
| MESH:D008654 |
Mesothelioma |
|
Selenium |
2.90 | 15107826 |
| MESH:D008664 |
Metal Metabolism, Inborn Errors |
|
Cyclosporine |
5.40 | 16801185 |
| MESH:D009402 |
Nephrosis, Lipoid |
|
Cyclosporine |
5.05 | 17954296 |
| MESH:D009404 |
Nephrotic Syndrome |
|
Cyclosporine |
3.61 | 19348381 18481113 |
| MESH:D019636 |
Neurodegenerative Diseases |
|
Acetaminophen |
3.18 | 18514411 |
| MESH:D009503 |
Neutropenia |
|
Vinblastine |
4.97 | 17378895 |
| MESH:D010146 |
Pain |
|
Acetaminophen |
2.69 | 16870215 |
| MESH:D010954 |
Plasmacytoma |
|
Selenium |
5.50 | 15087411 |
| MESH:D011230 |
Precancerous Conditions |
|
Cyclosporine |
3.55 | 12371664 |
| MESH:D011471 |
Prostatic Neoplasms |
|
biochanin A |
4.61 | 12111696 |
| MESH:D011565 |
Psoriasis |
|
Cyclosporine |
2.32 | 16882103 |
| MESH:D014581 |
Urticaria |
|
Acetaminophen |
3.38 | 10982225 |
| MESH:D014605 |
Uveitis |
|
Cyclosporine |
4.59 | 1336536 |
| MESH:D014625 |
Vaginal Neoplasms |
|
Vinblastine |
5.53 | 15577323 |
| MESH:D014985 |
Xerophthalmia |
|
Cyclosporine |
5.05 | 17120751 |
| Pathway ID |
Pathway Name |
|---|
| KEGG:00030 |
Pentose phosphate pathway |
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