Annotation Detail for KLHL5
Basic Information
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| Chemical ID |
Chemical Name |
Interaction |
Interaction Action |
Publication |
|---|
| D000082 |
Acetaminophen |
Acetaminophen affects the expression of KLHL5 mRNA | affects expression | 17562736
|
| D002117 |
Calcitriol |
Calcitriol results in increased expression of KLHL5 mRNA | increases expression | 16002434
|
| C029424 |
hydrazine |
hydrazine results in increased expression of KLHL5 mRNA | increases expression | 15282401
|
| D014635 |
Valproic Acid |
Valproic Acid results in increased expression of KLHL5 mRNA | increases expression | 19101580
|
| Disease ID |
Disease Name |
Direct Evidence |
Inference Chemical Name |
Inference Score |
Publication |
|---|
| MESH:D000014 |
Abnormalities, Drug-Induced |
|
Valproic Acid |
4.11 | 8875741 |
| MESH:D000015 |
Abnormalities, Multiple |
|
Valproic Acid |
4.35 | 19490988 |
| MESH:D000550 |
Amblyopia |
|
Valproic Acid |
5.96 | 17688650 |
| MESH:D000799 |
Angioedema |
|
Acetaminophen |
4.57 | 10982225 |
| MESH:D001008 |
Anxiety Disorders |
|
Valproic Acid |
3.90 | 17497229 |
| MESH:D001321 |
Autistic Disorder |
|
Acetaminophen |
1.86 | 18445737 |
| MESH:D001321 |
Autistic Disorder |
|
Valproic Acid |
1.86 | 15238991 17688650 18985861 18940202 20603192 18396377 17507914 18775368 18316065 17157402 18558336 18177632 19460635 19232924 16609825 |
| MESH:D001714 |
Bipolar Disorder |
|
Valproic Acid |
3.24 | 17594078 20046352 |
| MESH:D001848 |
Bone Diseases, Developmental |
|
Valproic Acid |
3.63 | 8888407 |
| MESH:D001943 |
Breast Neoplasms |
|
Calcitriol |
2.56 | 11237771 |
| MESH:D006528 |
Carcinoma, Hepatocellular |
|
Acetaminophen |
1.41 | 3084413 |
| MESH:D002294 |
Carcinoma, Squamous Cell |
|
Calcitriol |
2.71 | 11237771 |
| MESH:D002386 |
Cataract |
|
Acetaminophen |
2.79 | 10977129 |
| MESH:D002659 |
Child Development Disorders, Pervasive |
|
Valproic Acid |
2.82 | 20734317 |
| MESH:D019465 |
Craniofacial Abnormalities |
|
Valproic Acid |
1.91 | 16575769 17688650 8888407 |
| MESH:D056486 |
Drug-Induced Liver Injury |
|
Acetaminophen |
4.10 | 12153990 16177239 19923254 11461765 16485898 17522070 17562736 17906064 2444490 19416960 11743745 11421492 14550746 16781746 11739529 18071297 16393943 15968718 12958197 19085960 10774834 18713872 10663392 14725611 19164858 11287661 12540782 19739265 11529661 10915739 15619225 12705907 12392966 16081117 19420014 14986274 12594235 11834606 19370779 16227642 16109766 |
| MESH:D056486 |
Drug-Induced Liver Injury |
|
Valproic Acid |
4.10 | 19641884 1733752 |
| MESH:D056487 |
Drug-Induced Liver Injury, Chronic |
|
Acetaminophen |
4.82 | 19426721 |
| MESH:D004421 |
Dystonia |
|
Valproic Acid |
4.51 | 1851702 |
| MESH:D004681 |
Encephalomyelitis, Autoimmune, Experimental |
|
Calcitriol |
4.44 | 15138306 |
| MESH:D004831 |
Epilepsies, Myoclonic |
|
Valproic Acid |
4.71 | 17275665 3659116 |
| MESH:D004828 |
Epilepsies, Partial |
|
Valproic Acid |
4.64 | 3922381 16628512 |
| MESH:D004827 |
Epilepsy |
|
Valproic Acid |
3.11 | 20417680 18234410 |
| MESH:D004832 |
Epilepsy, Absence |
|
Valproic Acid |
3.96 | 6254150 7562514 6426943 |
| MESH:D017029 |
Epilepsy, Complex Partial |
|
Valproic Acid |
4.86 | 7750514 |
| MESH:D004830 |
Epilepsy, Tonic-Clonic |
|
Valproic Acid |
4.69 | 3659116 |
| MESH:D005234 |
Fatty Liver |
|
Valproic Acid |
3.72 | 19224547 14986274 |
| MESH:D005315 |
Fetal Diseases |
|
Valproic Acid |
5.61 | 16575769 |
| MESH:D005317 |
Fetal Growth Retardation |
|
Valproic Acid |
4.64 | 8888407 18558336 |
| MESH:D005756 |
Gastritis |
|
Acetaminophen |
4.40 | 16983495 |
| MESH:D006849 |
Hydrocephalus |
|
Valproic Acid |
5.50 | 17688650 |
| MESH:D006930 |
Hyperalgesia |
|
Acetaminophen |
3.02 | 16870215 |
| MESH:D007674 |
Kidney Diseases |
|
Acetaminophen |
2.40 | 12587719 15629191 |
| MESH:D015470 |
Leukemia, Myeloid, Acute |
|
Valproic Acid |
2.20 | 16294345 17596541 |
| MESH:D008107 |
Liver Diseases |
|
Acetaminophen |
1.70 | 19014921 16611625 19784758 12587719 19460945 11587558 16610002 12969438 |
| MESH:D017114 |
Liver Failure, Acute |
|
Acetaminophen |
3.63 | 16871587 17185352 |
| MESH:D017563 |
Lung Diseases, Interstitial |
|
Valproic Acid |
4.98 | 17228818 |
| MESH:D008546 |
Melanoma, Experimental |
|
Acetaminophen |
4.13 | 19513568 |
| MESH:D008881 |
Migraine Disorders |
|
Valproic Acid |
3.47 | 18765137 18803445 |
| MESH:D009139 |
Musculoskeletal Abnormalities |
|
Valproic Acid |
4.45 | 8888407 |
| MESH:D009190 |
Myelodysplastic Syndromes |
|
Valproic Acid |
3.35 | 17596541 |
| MESH:D009436 |
Neural Tube Defects |
|
Valproic Acid |
3.37 | 16359493 8888407 |
| MESH:D019636 |
Neurodegenerative Diseases |
|
Acetaminophen |
3.21 | 18514411 |
| MESH:D010146 |
Pain |
|
Acetaminophen |
2.73 | 16870215 |
| MESH:D011297 |
Prenatal Exposure Delayed Effects |
|
Valproic Acid |
4.46 | 20603192 |
| MESH:D011470 |
Prostatic Hyperplasia |
|
Calcitriol |
5.41 | 15572423 |
| MESH:D011471 |
Prostatic Neoplasms |
|
Calcitriol |
3.48 | 15754350 16289102 18247401 16644109 12479363 |
| MESH:D019310 |
Pseudolymphoma |
|
Valproic Acid |
5.26 | 11422049 12752131 |
| MESH:D012208 |
Rhabdomyosarcoma |
|
Valproic Acid |
4.64 | 19155313 |
| MESH:D012559 |
Schizophrenia |
|
Valproic Acid |
2.10 | 19110320 15737665 |
| MESH:D012640 |
Seizures |
|
Valproic Acid |
2.99 | 11044598 17978042 3137016 16876388 14763951 11738929 1511512 15475178 |
| MESH:D016135 |
Spinal Dysraphism |
|
Valproic Acid |
4.09 | 19490988 |
| MESH:D013226 |
Status Epilepticus |
|
Valproic Acid |
5.26 | 12833885 |
| MESH:D014178 |
Translocation, Genetic |
|
Valproic Acid |
5.96 | 17262798 |
| MESH:D020194 |
Unverricht-Lundborg Syndrome |
|
Valproic Acid |
5.15 | 3119515 |
| MESH:D014564 |
Urogenital Abnormalities |
|
Valproic Acid |
5.20 | 8888407 |
| MESH:D014581 |
Urticaria |
|
Acetaminophen |
3.44 | 10982225 |
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