Annotation Detail for SUV420H1
Basic Information
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| Gene Symbol: | SUV420H1 ( CGI85,KMT5B,MGC118906,MGC118909,MGC21161,MGC703 ) |
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| Gene Full Name: | suppressor of variegation 4-20 homolog 1 (Drosophila) |
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| Band: | 11q13.2 |
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| Quick Links | Entrez ID:51111; OMIM: 610881; Uniprot ID:SV421_HUMAN; ENSEMBL ID: ENSG00000110066; HGNC ID: |
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| Relate to Another Database: |
SFARIGene;
denovo-db |
| Pathway ID | Pathway Name |
|---|
| hsa00310 | Lysine degradation |
| Pathway ID | Pathway Name |
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| 200077 | Glucocorticoid receptor regulatory network |
| Chemical ID |
Chemical Name |
Interaction |
Interaction Action |
Publication |
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| C548651 |
2-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester |
2-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester results in decreased expression of SUV420H1 mRNA | decreases expression | 19933214
|
| C075773 |
4-phenylbutyric acid |
4-phenylbutyric acid results in decreased expression of SUV420H1 mRNA | decreases expression | 14583596
|
| D015123 |
7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide |
7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of SUV420H1 mRNA | decreases expression | 20018196
|
| D020122 |
tert-Butylhydroperoxide |
tert-Butylhydroperoxide results in decreased expression of SUV420H1 mRNA | decreases expression | 15336504
|
| D019772 |
Topotecan |
SUV420H1 protein affects the susceptibility to Topotecan | affects response to substance | 16217747
|
| Disease ID |
Disease Name |
Direct Evidence |
Inference Chemical Name |
Inference Score |
Publication |
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| MESH:D002471 |
Cell Transformation, Neoplastic |
|
7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide |
2.96 | 20889678 |
| MESH:D004938 |
Esophageal Neoplasms |
|
7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide |
2.14 | 20426865 |
| MESH:D009369 |
Neoplasms |
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4-phenylbutyric acid |
3.86 | 19116145 |
| MESH:D009447 |
Neuroblastoma |
|
Topotecan |
4.00 | 15176712 |
| MESH:D012878 |
Skin Neoplasms |
|
tert-Butylhydroperoxide |
2.83 | 8532709 |
| Pathway ID |
Pathway Name |
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| KEGG:00310 |
Lysine degradation |
Pharmacogenomics Knowledge Base