AutismKB 2.0

Annotation Detail for MRPS2


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:MRPS2 ( MRP-S2,S2mt )
Gene Full Name: mitochondrial ribosomal protein S2
Band: 9q34.3
Quick LinksEntrez ID:51116; OMIM: 611971; Uniprot ID:RT02_HUMAN; ENSEMBL ID: ENSG00000122140; HGNC ID: 14495
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C009505 4,4'-diaminodiphenylmethane 4,4'-diaminodiphenylmethane results in increased expression of MRPS2 mRNAincreases expression 18648102
D000082 Acetaminophen Acetaminophen affects the expression of MRPS2 mRNAaffects expression 17562736
D002995 Clofibric Acid [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of MRPS2 mRNAaffects cotreatment|affects expression 17602206
D004052 Diethylnitrosamine [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of MRPS2 mRNAaffects cotreatment|affects expression 17602206
D018038 Sodium Selenite Sodium Selenite results in increased expression of MRPS2 mRNAincreases expression 18175754
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000236 Adenoma 4,4'-diaminodiphenylmethane 7.293712494
MESH:D000236 Adenoma Diethylnitrosamine 7.2910737359 6695378
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 4.4416434500 17620307 18056438 19052882 19061943 17162532
MESH:D000799 Angioedema Acetaminophen 4.4510982225
MESH:D001321 Autistic Disorder Acetaminophen 1.4018445737
MESH:D001660 Biliary Tract Diseases 4,4'-diaminodiphenylmethane 5.631440618 11289319
MESH:D001943 Breast Neoplasms Diethylnitrosamine 2.1917474063
MESH:D006528 Carcinoma, Hepatocellular 4,4'-diaminodiphenylmethane 4.773581430 7296757
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 4.773084413
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 4.7719519916 16502159 10737359 18785209 19383236 19919837 18978308 19052882 19107877 18788625 16569478 19701751 16935385 19394651 16698587 16807293 20101231 18393292 20214788 18506893 19822196 19335982 18056438 20727157 19418558 16328049 18665156 19539802 20935162 17978847 18691550 20514400 16681979 17761372 17162532 18210153 20512989 3581430 20432363 19171122 16830150 17138121 16779866 3084413 20007298 20084675 17428255 17173139 19208518 16288022 11831363 16878318 16540662 10672840 18971187 17055752 21159647 18494052 20524982
MESH:D002292 Carcinoma, Renal Cell 4,4'-diaminodiphenylmethane 2.817296757
MESH:D002386 Cataract Acetaminophen 2.7710977129
MESH:D002471 Cell Transformation, Neoplastic 4,4'-diaminodiphenylmethane 7.487505956
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 7.482727394 17174075 21159647 7505956
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 4.0119052882
MESH:D002779 Cholestasis 4,4'-diaminodiphenylmethane 3.4119486331 9022650
MESH:D019457 Chromosome Breakage Sodium Selenite 5.2415894690
MESH:D017449 Dermatitis, Allergic Contact 4,4'-diaminodiphenylmethane 3.2818759878 2524372 8156756 8970840 11298694 14531868 12868966 11906362
MESH:D003877 Dermatitis, Contact 4,4'-diaminodiphenylmethane 3.893621924 2952479
MESH:D003920 Diabetes Mellitus Sodium Selenite 4.1016285004
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 2.2520387270
MESH:D056486 Drug-Induced Liver Injury 4,4'-diaminodiphenylmethane 9.708291058 18692083 9022650 18289764 9653073 18648102 1440618 11289319 9328219 6482804 16192314 7440962 6679447
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 9.7011529661 12153990 19923254 17906064 19370779 10915739 2444490 14986274 16485898 19739265 15619225 18071297 16109766 15968718 12392966 12958197 16393943 11461765 19164858 12705907 11743745 11287661 11739529 16177239 14550746 16081117 12594235 10663392 17562736 16781746 12540782 16227642 10774834 17522070 19420014 11834606 18713872 14725611 19416960 11421492 19085960
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 9.7019107877
MESH:D056486 Drug-Induced Liver Injury Sodium Selenite 9.7015131321
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.7119426721
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 5.7316302075
MESH:D004938 Esophageal Neoplasms 4,4'-diaminodiphenylmethane 2.173581430
MESH:D005234 Fatty Liver Diethylnitrosamine 3.5620387270 21071580
MESH:D005350 Fibroma 4,4'-diaminodiphenylmethane 5.636705139
MESH:D005756 Gastritis Acetaminophen 4.2916983495
MESH:D006042 Goiter 4,4'-diaminodiphenylmethane 4.447505956
MESH:D006505 Hepatitis 4,4'-diaminodiphenylmethane 3.956705139
MESH:D006930 Hyperalgesia Acetaminophen 2.9916870215
MESH:D006965 Hyperplasia 4,4'-diaminodiphenylmethane 4.4215034207
MESH:D007249 Inflammation Diethylnitrosamine 2.5318785209
MESH:D007333 Insulin Resistance Sodium Selenite 3.4914714311
MESH:D007565 Jaundice 4,4'-diaminodiphenylmethane 5.638074119 9022650
MESH:D007674 Kidney Diseases Acetaminophen 2.3812587719 15629191
MESH:D007680 Kidney Neoplasms 4,4'-diaminodiphenylmethane 3.276582329
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 2.9920032147 18407596 18665156 19638242 18522880
MESH:D008105 Liver Cirrhosis, Biliary 4,4'-diaminodiphenylmethane 3.409327722 15034207
MESH:D008107 Liver Diseases Acetaminophen 4.1512587719 19460945 16611625 19014921 11587558 12969438 16610002 19784758
MESH:D008107 Liver Diseases Diethylnitrosamine 4.1517034775
MESH:D017114 Liver Failure, Acute Acetaminophen 3.5817185352 16871587
MESH:D008113 Liver Neoplasms Clofibric Acid 5.1317602206
MESH:D008113 Liver Neoplasms Diethylnitrosamine 5.1318754104 18648771 20137499 20583210 12771043 19833225 19638242 10737359 19499222 19255062 21278145 19073162 19426721 19850985 20452335 21071580 19294768 19642983 12112319 20501860 19690152 18978307 18644402 20101389 19812893 15175105 21047994 19090486 19551842 20492335 16942905 20405173 19254457 21167192 19427195 19996281 19256749 18977376 15885732 20434301 20118626 2422723 9163691 2862719
MESH:D008114 Liver Neoplasms, Experimental 4,4'-diaminodiphenylmethane 6.613712494 1399818 6587162 598648
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 6.6118775883 18093689 16267830 9362446 19009564 18308698 18079962 16842330 18544905 17174075 19539802 19519916 3124819 21159647 17942915 18253720 19126423 18164116 19004024 2563599 17854601 18282651
MESH:D008175 Lung Neoplasms Diethylnitrosamine 1.7620512841 21163286 6695378 20970405
MESH:D016393 Lymphoma, B-Cell Sodium Selenite 4.4614737004
MESH:D008546 Melanoma, Experimental Acetaminophen 4.0519513568
MESH:D009362 Neoplasm Metastasis 4,4'-diaminodiphenylmethane 6.093581430
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 6.099029167 3581430
MESH:D009436 Neural Tube Defects 4,4'-diaminodiphenylmethane 3.136679447
MESH:D019636 Neurodegenerative Diseases Acetaminophen 9.2218514411
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 9.2220387270
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 5.7320387270
MESH:D009784 Occupational Diseases 4,4'-diaminodiphenylmethane 3.774026338 6482804
MESH:D009902 Optic Neuritis 4,4'-diaminodiphenylmethane 5.633988306
MESH:D010146 Pain Acetaminophen 2.6916870215
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 2.5216540662
MESH:D010212 Papilloma 4,4'-diaminodiphenylmethane 3.977296757
MESH:D010787 Photosensitivity Disorders 4,4'-diaminodiphenylmethane 5.086228378
MESH:D011230 Precancerous Conditions Diethylnitrosamine 3.882563599
MESH:D011471 Prostatic Neoplasms Sodium Selenite 3.3418760546
MESH:D012162 Retinal Degeneration 4,4'-diaminodiphenylmethane 3.643692021
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 1.7618456281
MESH:D013964 Thyroid Neoplasms 4,4'-diaminodiphenylmethane 8.041399818 3712494 6587162 6582329 7505956
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 8.047505956
MESH:D001749 Urinary Bladder Neoplasms 4,4'-diaminodiphenylmethane 2.398074119
MESH:D014581 Urticaria Acetaminophen 3.3810982225
No data
Pharmacogenomics Knowledge Base Top
Drug Bank Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved