AutismKB 2.0

Annotation Detail for ZNF706


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Basic Information Top
Gene Symbol:ZNF706 ( PNAS-106,PNAS-113 )
Gene Full Name: zinc finger protein 706
Band: 8q22.3
Quick LinksEntrez ID:51123; OMIM: NA; Uniprot ID:ZN706_HUMAN; ENSEMBL ID: ENSG00000120963; HGNC ID: 24992
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D001564 Benzo(a)pyrene Benzo(a)pyrene results in decreased expression of ZNF706 mRNAdecreases expression 20064835
C110904 capecitabine ZNF706 protein results in increased susceptibility to capecitabineincreases response to substance 16734730
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 2.0720127859 20464547
MESH:D000236 Adenoma Benzo(a)pyrene 2.906695378
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 4.8419183758
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 2.6220146248 17474063
MESH:D001943 Breast Neoplasms capecitabine 2.6218473752 12972520
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 2.1520419170
MESH:D015179 Colorectal Neoplasms capecitabine 3.3218448328 18473752
MESH:D003329 Coronary Vasospasm capecitabine 6.4817465463
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 2.0916530937
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 2.8720471113
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 2.1820195826 21137059
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 1.5720135361 18520028 6695378 18816296 20064080 17053015 18569708 20869020 20464547
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 3.5716381670
MESH:D009362 Neoplasm Metastasis capecitabine 4.2812972520
MESH:D009369 Neoplasms Benzo(a)pyrene 6.2311141357
MESH:D009369 Neoplasms capecitabine 6.2316374040
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 2.9017292933
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 2.5519755658 10029692
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 1.562093021 20155912
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 2.3217053015
No data
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA142670505
    • No data
    Releated disease ID Related disease Name
    PA445062Neoplasms
    No data
    Drug Bank Top

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    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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