AutismKB 2.0

Annotation Detail for TRIM17


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:TRIM17 ( RBCC,RNF16,terf )
Gene Full Name: tripartite motif-containing 17
Band: 1q42.13
Quick LinksEntrez ID:51127; OMIM: 606123; Uniprot ID:TRI17_HUMAN; ENSEMBL ID: ENSG00000162931; HGNC ID: 13430
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C009505 4,4'-diaminodiphenylmethane 4,4'-diaminodiphenylmethane results in increased expression of TRIM17 mRNAincreases expression 18648102
D000643 Ammonium Chloride Ammonium Chloride affects the expression of TRIM17 mRNAaffects expression 16483693
C055494 caffeic acid phenethyl ester [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in increased expression of TRIM17 mRNAaffects cotreatment|increases expression 20360939
D004052 Diethylnitrosamine [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in increased expression of TRIM17 mRNAaffects cotreatment|increases expression 20360939
C116926 rofecoxib rofecoxib affects the expression of TRIM17 mRNAaffects expression 17070997
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000138 Acidosis Ammonium Chloride 4.1018287403
MESH:D000236 Adenoma 4,4'-diaminodiphenylmethane 7.293712494
MESH:D000236 Adenoma Diethylnitrosamine 7.296695378 10737359
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 4.4417620307 16434500 19052882 18056438 17162532 19061943
MESH:D001169 Arthritis, Experimental rofecoxib 4.5416690336
MESH:D001660 Biliary Tract Diseases 4,4'-diaminodiphenylmethane 5.6311289319 1440618
MESH:D001943 Breast Neoplasms Diethylnitrosamine 2.1917474063
MESH:D006528 Carcinoma, Hepatocellular 4,4'-diaminodiphenylmethane 3.127296757 3581430
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 3.1219701751 10737359 17138121 19107877 3084413 10672840 16288022 19919837 19171122 19394651 21159647 19335982 17978847 3581430 17173139 18494052 18210153 18978308 18506893 20084675 19822196 18788625 20007298 20101231 18393292 16569478 19539802 11831363 16779866 19383236 17761372 16502159 19052882 20512989 18691550 20727157 18665156 16807293 16681979 17428255 20935162 16540662 17055752 20514400 20432363 16935385 18971187 20524982 19418558 19208518 20214788 16328049 16878318 16830150 17162532 18056438 18785209 19519916 16698587
MESH:D002292 Carcinoma, Renal Cell 4,4'-diaminodiphenylmethane 2.817296757
MESH:D002471 Cell Transformation, Neoplastic 4,4'-diaminodiphenylmethane 7.487505956
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 7.482727394 17174075 21159647 7505956
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 4.0119052882
MESH:D002779 Cholestasis 4,4'-diaminodiphenylmethane 3.4119486331 9022650
MESH:D003110 Colonic Neoplasms rofecoxib 3.3412902858
MESH:D017449 Dermatitis, Allergic Contact 4,4'-diaminodiphenylmethane 3.282524372 11298694 11906362 12868966 14531868 8970840 8156756 18759878
MESH:D003877 Dermatitis, Contact 4,4'-diaminodiphenylmethane 3.893621924 2952479
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 2.2520387270
MESH:D056486 Drug-Induced Liver Injury 4,4'-diaminodiphenylmethane 4.1618289764 16192314 9022650 8291058 18692083 9328219 6482804 7440962 11289319 18648102 1440618 9653073 6679447
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 4.1619107877
MESH:D004715 Endometriosis rofecoxib 5.2015652904
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 5.7316302075
MESH:D004938 Esophageal Neoplasms 4,4'-diaminodiphenylmethane 2.173581430
MESH:D005234 Fatty Liver Diethylnitrosamine 3.5620387270 21071580
MESH:D005350 Fibroma 4,4'-diaminodiphenylmethane 5.636705139
MESH:D006042 Goiter 4,4'-diaminodiphenylmethane 4.447505956
MESH:D006505 Hepatitis 4,4'-diaminodiphenylmethane 3.956705139
MESH:D006965 Hyperplasia 4,4'-diaminodiphenylmethane 4.4215034207
MESH:D007249 Inflammation Diethylnitrosamine 2.5318785209
MESH:D007410 Intestinal Diseases rofecoxib 5.5215831440
MESH:D007414 Intestinal Neoplasms caffeic acid phenethyl ester 4.9310783313
MESH:D007417 Intestinal Polyps rofecoxib 5.7711245490
MESH:D007565 Jaundice 4,4'-diaminodiphenylmethane 5.638074119 9022650
MESH:D007674 Kidney Diseases caffeic acid phenethyl ester 3.7315369732
MESH:D007680 Kidney Neoplasms 4,4'-diaminodiphenylmethane 3.276582329
MESH:D015473 Leukemia, Promyelocytic, Acute caffeic acid phenethyl ester 4.2116766008
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 2.9920032147 19638242 18665156 18522880 18407596
MESH:D008105 Liver Cirrhosis, Biliary 4,4'-diaminodiphenylmethane 3.4015034207 9327722
MESH:D008106 Liver Cirrhosis, Experimental rofecoxib 3.0817565644
MESH:D008107 Liver Diseases Diethylnitrosamine 2.1617034775
MESH:D008113 Liver Neoplasms Diethylnitrosamine 2.3419833225 19294768 19426721 18977376 19499222 20405173 19690152 20101389 19073162 18978307 19427195 15175105 12771043 18648771 16942905 2862719 19638242 19090486 12112319 19850985 19812893 21071580 20452335 21167192 18754104 20434301 21278145 21047994 20137499 19256749 18644402 19551842 19254457 20501860 19255062 15885732 19996281 19642983 9163691 10737359 20492335 20583210 2422723 20118626
MESH:D008114 Liver Neoplasms, Experimental 4,4'-diaminodiphenylmethane 6.616587162 1399818 3712494 598648
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 6.6118775883 17854601 18093689 18164116 18544905 3124819 18079962 18253720 19126423 17942915 9362446 16842330 19539802 19004024 2563599 16267830 19519916 17174075 19009564 18308698 18282651 21159647
MESH:D008175 Lung Neoplasms Diethylnitrosamine 1.7620512841 21163286 20970405 6695378
MESH:D009362 Neoplasm Metastasis 4,4'-diaminodiphenylmethane 6.093581430
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 6.099029167 3581430
MESH:D009436 Neural Tube Defects 4,4'-diaminodiphenylmethane 3.136679447
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 3.6520387270
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 5.7320387270
MESH:D009784 Occupational Diseases 4,4'-diaminodiphenylmethane 3.774026338 6482804
MESH:D009902 Optic Neuritis 4,4'-diaminodiphenylmethane 5.633988306
MESH:D010003 Osteoarthritis rofecoxib 4.5716690336
MESH:D010149 Pain, Postoperative rofecoxib 6.0016678543 18165598
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 2.5216540662
MESH:D010212 Papilloma 4,4'-diaminodiphenylmethane 3.977296757
MESH:D010787 Photosensitivity Disorders 4,4'-diaminodiphenylmethane 5.086228378
MESH:D011230 Precancerous Conditions Diethylnitrosamine 3.882563599
MESH:D012162 Retinal Degeneration 4,4'-diaminodiphenylmethane 3.643692021
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 1.7618456281
MESH:D013964 Thyroid Neoplasms 4,4'-diaminodiphenylmethane 8.043712494 6582329 6587162 7505956 1399818
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 8.047505956
MESH:D001749 Urinary Bladder Neoplasms 4,4'-diaminodiphenylmethane 2.398074119
No data
Pharmacogenomics Knowledge Base Top
Drug Bank Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved