AutismKB 2.0

Annotation Detail for ANGPTL4


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:ANGPTL4 ( ANGPTL2,ARP4,FIAF,HFARP,NL2,PGAR,pp1158 )
Gene Full Name: angiopoietin-like 4
Band: 19p13.2
Quick LinksEntrez ID:51129; OMIM: 605910; Uniprot ID:ANGL4_HUMAN; ENSEMBL ID: ENSG00000167772; HGNC ID: 16039
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa03320PPAR signaling pathway
Pathway IDPathway Name
Metabolism of lipids and lipoproteins
No data
No data
No data
Related Diseases/Disorders Top
No data
No data
Desease Name
HDL cholesterol
METABOLIC
Desease Name
HDL cholesterol
Desease Name
Reduced triglycerides, susceptibility to
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C404910 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the expression of ANGPTL4 mRNAaffects expression 19414516
C404910 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of ANGPTL4 mRNA]affects expression|affects reaction 19414516
C404910 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [FSHB protein affects the expression of ANGPTL4 mRNA]affects expression|affects reaction 19414516
C009505 4,4'-diaminodiphenylmethane 4,4'-diaminodiphenylmethane results in increased expression of ANGPTL4 mRNAincreases expression 18648102
C035207 4-amino-2,6-dinitrotoluene 4-amino-2,6-dinitrotoluene affects the expression of ANGPTL4 mRNAaffects expression 21346803
D000082 Acetaminophen Acetaminophen affects the expression of ANGPTL4 mRNAaffects expression 17562736
D000242 Cyclic AMP 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of ANGPTL4 mRNA]affects expression|affects reaction 19414516
D000643 Ammonium Chloride Ammonium Chloride affects the expression of ANGPTL4 mRNAaffects expression 16483693
D001564 Benzo(a)pyrene Benzo(a)pyrene results in increased expression of ANGPTL4 mRNAincreases expression 20064835
D001629 Bezafibrate Bezafibrate results in increased expression of ANGPTL4 mRNAincreases expression 17118139
D002251 Carbon Tetrachloride Carbon Tetrachloride results in increased expression of ANGPTL4 mRNAincreases expression 17484886
D002995 Clofibric Acid [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of ANGPTL4 mRNAaffects cotreatment|affects expression 17602206
D003035 Cobalt [tungsten carbide binds to Cobalt] which results in increased expression of ANGPTL4 mRNAaffects binding|increases expression 20105288
C018021 cobaltous chloride cobaltous chloride results in increased expression of ANGPTL4 mRNAincreases expression 20105288
D003314 Corn Oil Corn Oil affects the expression of ANGPTL4 mRNAaffects expression 16360708
C014347 decitabine decitabine results in increased expression of ANGPTL4 mRNAincreases expression 17908484
D003907 Dexamethasone [Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of ANGPTL4 mRNAaffects cotreatment|increases expression 16054899
D003907 Dexamethasone [Tetrachlorodibenzodioxin co-treated with EGF protein] inhibits the reaction [[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of ANGPTL4 mRNA]affects cotreatment|decreases reaction|increases expression 16054899
D003907 Dexamethasone Tetrachlorodibenzodioxin inhibits the reaction [[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of ANGPTL4 mRNA]affects cotreatment|decreases reaction|increases expression 16054899
D004041 Dietary Fats Dietary Fats results in decreased expression of ANGPTL4 mRNAdecreases expression 18042831
D004041 Dietary Fats Dietary Fats results in increased expression of ANGPTL4 mRNAincreases expression 18457598
16357043
D004052 Diethylnitrosamine [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of ANGPTL4 mRNAaffects cotreatment|affects expression 17602206
D005230 Fatty Acids, Nonesterified ANGPTL4 protein results in increased abundance of Fatty Acids, Nonesterifiedincreases abundance 19805517
D011345 Fenofibrate Fenofibrate results in increased expression of ANGPTL4 mRNAincreases expression 17118139
D005472 Fluorouracil ANGPTL4 protein affects the susceptibility to Fluorouracilaffects response to substance 16217747
D005947 Glucose Glucose results in increased expression of ANGPTL4 mRNAincreases expression 16805838
D005990 Glycerol ANGPTL4 protein affects the abundance of Glycerolaffects abundance 19805517
D007213 Indomethacin Indomethacin results in increased expression of ANGPTL4 mRNAincreases expression 16984733
D015056 1-Methyl-3-isobutylxanthine [Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of ANGPTL4 mRNAaffects cotreatment|increases expression 16054899
D015056 1-Methyl-3-isobutylxanthine [Tetrachlorodibenzodioxin co-treated with EGF protein] inhibits the reaction [[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of ANGPTL4 mRNA]affects cotreatment|decreases reaction|increases expression 16054899
D015056 1-Methyl-3-isobutylxanthine Tetrachlorodibenzodioxin inhibits the reaction [[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of ANGPTL4 mRNA]affects cotreatment|decreases reaction|increases expression 16054899
D008345 Manganese Manganese results in increased expression of ANGPTL4 mRNAincreases expression 17175027
C025340 manganese chloride manganese chloride results in increased expression of ANGPTL4 mRNAincreases expression 17175027
C002950 methylformamide methylformamide analog results in increased expression of ANGPTL4 mRNAincreases expression 17040096
C002950 methylformamide methylformamide results in increased expression of ANGPTL4 mRNAincreases expression 17040096
D008770 Methylnitrosourea Methylnitrosourea results in increased expression of ANGPTL4 mRNAincreases expression 17412507
C452423 N-(4-bromo-2-fluorophenyl)-6-methoxy-7-((1-methylpiperidin-4-yl)methoxy)quinazolin-4-amine N-(4-bromo-2-fluorophenyl)-6-methoxy-7-((1-methylpiperidin-4-yl)methoxy)quinazolin-4-amine results in increased expression of ANGPTL4 mRNAincreases expression 16052530
D010100 Oxygen Oxygen deficiency results in increased expression of ANGPTL4 mRNAincreases expression 17175027
D010126 Ozone Ozone results in increased expression of ANGPTL4 mRNAincreases expression 17095637
C041786 palm oil palm oil results in decreased expression of ANGPTL4 mRNAdecreases expression 18042831
C023036 perfluorooctanoic acid perfluorooctanoic acid results in increased expression of ANGPTL4 mRNAincreases expression 18467677
D010634 Phenobarbital Phenobarbital results in decreased expression of ANGPTL4 mRNAdecreases expression 19270015
D010634 Phenobarbital Phenobarbital results in increased expression of ANGPTL4 mRNAincreases expression 19270015
D010656 Phenylephrine Phenylephrine results in decreased expression of ANGPTL4 mRNAdecreases expression 18158353
C006253 pirinixic acid pirinixic acid results in decreased expression of ANGPTL4 mRNAdecreases expression 16985257
C006253 pirinixic acid pirinixic acid results in increased expression of ANGPTL4 mRNAincreases expression 18445702
16357043
17426115
18301758
17118139
C006253 pirinixic acid MDM2 protein promotes the reaction [[pirinixic acid results in increased activity of PPARA protein] which results in increased expression of ANGPTL4 mRNA]increases activity|increases expression|increases reaction 19103650
C006253 pirinixic acid [pirinixic acid results in increased activity of PPARA protein] which results in increased expression of ANGPTL4 mRNAincreases activity|increases expression 19103650
C006253 pirinixic acid pirinixic acid results in increased expression of ANGPTL4 mRNAincreases expression 16940010
C089730 rosiglitazone [Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of ANGPTL4 mRNAaffects cotreatment|increases expression 16054899
C089730 rosiglitazone [Tetrachlorodibenzodioxin co-treated with EGF protein] inhibits the reaction [[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of ANGPTL4 mRNA]affects cotreatment|decreases reaction|increases expression 16054899
C089730 rosiglitazone Tetrachlorodibenzodioxin inhibits the reaction [[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of ANGPTL4 mRNA]affects cotreatment|decreases reaction|increases expression 16054899
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with EGF protein] inhibits the reaction [[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of ANGPTL4 mRNA]affects cotreatment|decreases reaction|increases expression 16054899
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with EGF protein] results in decreased expression of ANGPTL4 mRNAaffects cotreatment|decreases expression 16054899
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin inhibits the reaction [[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of ANGPTL4 mRNA]affects cotreatment|decreases reaction|increases expression 16054899
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of ANGPTL4 mRNAdecreases expression 16054899
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of ANGPTL4 mRNAincreases expression 16960034
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of ANGPTL4 mRNAincreases expression 16960034
D014280 Triglycerides ANGPTL4 protein results in increased abundance of Triglyceridesincreases abundance 19805517
C002802 tungsten carbide [tungsten carbide binds to Cobalt] which results in increased expression of ANGPTL4 mRNAaffects binding|increases expression 20105288
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced 4-amino-2,6-dinitrotoluene 11.847525203
MESH:D000014 Abnormalities, Drug-Induced Phenobarbital 11.846195326
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 11.8411752688 14514962 15322242
MESH:D000138 Acidosis Ammonium Chloride 3.1418287403
MESH:D055371 Acute Lung Injury Oxygen 7.9516759491
MESH:D055371 Acute Lung Injury pirinixic acid 7.9518653653
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 9.2420127859 20464547
MESH:D000230 Adenocarcinoma Fluorouracil 9.2417638652
MESH:D000230 Adenocarcinoma Indomethacin 9.2416537180
MESH:D000230 Adenocarcinoma Methylnitrosourea 9.2415688392 15113128
MESH:D000236 Adenoma 4,4'-diaminodiphenylmethane 13.923712494
MESH:D000236 Adenoma Benzo(a)pyrene 13.926695378
MESH:D000236 Adenoma Diethylnitrosamine 13.9210737359 6695378
MESH:D000236 Adenoma Indomethacin 13.9211497255
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 21.4117620307 19052882 19061943 16434500 18056438 17162532
MESH:D018248 Adenoma, Liver Cell Phenobarbital 21.4117620307
MESH:D018248 Adenoma, Liver Cell pirinixic acid 21.4116434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 21.4116835633
MESH:D016301 Alveolar Bone Loss Indomethacin 4.9417225004
MESH:D000544 Alzheimer Disease Indomethacin 6.1217627676 15579461
MESH:D000544 Alzheimer Disease Ozone 6.1215513908
MESH:D000544 Alzheimer Disease rosiglitazone 6.1219621015
MESH:D000740 Anemia Fluorouracil 7.4816511603 15504547 17963324
MESH:D000740 Anemia Tetrachlorodibenzodioxin 7.4811748828
MESH:D000756 Anemia, Sideroblastic Manganese 9.7816910769
MESH:D000756 Anemia, Sideroblastic manganese chloride 9.7816910769
MESH:D000799 Angioedema Acetaminophen 3.4210982225
MESH:D000860 Anoxia Oxygen 4.6420872349
MESH:D001014 Aortic Aneurysm Indomethacin 4.4510231640
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 10.3519183758
MESH:D017544 Aortic Aneurysm, Abdominal Indomethacin 10.3510388637
MESH:D001145 Arrhythmias, Cardiac Phenylephrine 3.7517460149
MESH:D001161 Arteriosclerosis Dietary Fats 3.4815238619
MESH:D018771 Arthralgia Indomethacin 4.742160914
MESH:D001169 Arthritis, Experimental Dexamethasone 3.2817659584
MESH:D001172 Arthritis, Rheumatoid Indomethacin 4.4911248219
MESH:D001172 Arthritis, Rheumatoid Ozone 4.4915570426
MESH:D001249 Asthma Ozone 2.5017854713 16373670
MESH:D050197 Atherosclerosis Oxygen 3.5516391483
MESH:D001321 Autistic Disorder Acetaminophen 1.4718445737
MESH:D001477 Bartter Syndrome Indomethacin 4.5710684365
MESH:D001660 Biliary Tract Diseases 4,4'-diaminodiphenylmethane 4.591440618 11289319
MESH:D001778 Blood Coagulation Disorders pirinixic acid 7.5319483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 7.5312125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.3615340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.4915746008
MESH:D001919 Bradycardia Phenylephrine 4.1315306635
MESH:D001929 Brain Edema Indomethacin 4.6011481608
MESH:D002545 Brain Ischemia Indomethacin 4.0012524144
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 6.4617474063 20146248
MESH:D001943 Breast Neoplasms Cobalt 6.4615986119
MESH:D001943 Breast Neoplasms decitabine 6.4618320071 19208741
MESH:D001943 Breast Neoplasms Dietary Fats 6.4620435547
MESH:D001943 Breast Neoplasms Diethylnitrosamine 6.4617474063
MESH:D001943 Breast Neoplasms Fluorouracil 6.4619217205 18608205 16110121 16557594 18357371 15136595 16595493
MESH:D001943 Breast Neoplasms Indomethacin 6.4617401462
MESH:D001943 Breast Neoplasms Methylnitrosourea 6.4614633655 16253758 11306469
MESH:D001943 Breast Neoplasms Oxygen 6.4617263869
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 6.4620435547
MESH:D016535 Bronchial Hyperreactivity Ozone 3.3516777450 14754758 15516495 19059883 18417511 18315731 17626835
MESH:D002056 Burns Indomethacin 4.3010459503
MESH:D002100 Cachexia Indomethacin 11.0015625704 11239499 16537180 15141370
MESH:D002100 Cachexia Ozone 11.0016183385
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 3.3715673190 16011737 18705752 16192424 16227642 16124888 15721981 16097048 15700767 16050911 10355542 3786805
MESH:D002276 Carcinoid Tumor Fluorouracil 4.2416051944
MESH:D002277 Carcinoma Fluorouracil 7.0917121937
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 7.0916835633
MESH:D006528 Carcinoma, Hepatocellular 4,4'-diaminodiphenylmethane 12.837296757 3581430
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 12.833084413
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 12.8318788625
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 12.8317162532 16569478 16502159 19052882 18788625 19919837 18056438 18210153 18971187 17055752 16681979 3084413 20514400 20214788 18691550 16935385 20101231 19208518 19418558 17761372 10737359 10672840 19383236 20727157 18494052 18393292 19107877 20007298 16878318 16830150 18978308 17138121 20432363 11831363 16328049 18785209 18665156 19539802 20512989 19335982 21159647 19701751 17428255 19394651 20524982 18506893 19171122 3581430 16807293 17173139 19822196 16540662 17978847 16698587 16288022 20935162 16779866 20084675 19519916
MESH:D006528 Carcinoma, Hepatocellular Fluorouracil 12.8316332177 17971768 16799960 18930000 17045692 17088986
MESH:D006528 Carcinoma, Hepatocellular Indomethacin 12.8316391822
MESH:D006528 Carcinoma, Hepatocellular Phenobarbital 12.831701930 20935162 6705139 20007298 17173139
MESH:D018827 Carcinoma, Lewis Lung Indomethacin 4.3111053908
MESH:D018276 Carcinoma, Medullary Indomethacin 4.9318791128 14736730 11352223
MESH:D002292 Carcinoma, Renal Cell 4,4'-diaminodiphenylmethane 9.607296757
MESH:D002292 Carcinoma, Renal Cell Fluorouracil 9.6018695887
MESH:D002292 Carcinoma, Renal Cell Indomethacin 9.6017341418
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 9.6820419170
MESH:D002294 Carcinoma, Squamous Cell decitabine 9.6819215824
MESH:D002294 Carcinoma, Squamous Cell Fluorouracil 9.6818986760 17066447 16280240 16757204
MESH:D002294 Carcinoma, Squamous Cell Indomethacin 9.6815482327 12636206
MESH:D006332 Cardiomegaly Phenylephrine 6.0811754973 15728586 16170337 17287366 17124262 11179087
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 6.0816120746 18670907 18850075
MESH:D002386 Cataract 4-amino-2,6-dinitrotoluene 11.0314694615
MESH:D002386 Cataract Acetaminophen 11.0310977129
MESH:D002386 Cataract Methylnitrosourea 11.0312484553
MESH:D002471 Cell Transformation, Neoplastic 4,4'-diaminodiphenylmethane 9.647505956
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 9.6417174075 2727394 21159647 7505956
MESH:D002471 Cell Transformation, Neoplastic Methylnitrosourea 9.647505956 2727394
MESH:D002493 Central Nervous System Diseases Phenobarbital 3.844080065
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 8.1519052882
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 8.1516835633
MESH:D002764 Cholecystitis Indomethacin 4.7411181007
MESH:D002779 Cholestasis 4,4'-diaminodiphenylmethane 6.819022650 19486331
MESH:D002779 Cholestasis pirinixic acid 6.8119176532
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 1.928697196 15668235 12621046 15340226 16354765
MESH:D003110 Colonic Neoplasms decitabine 7.5717616700
MESH:D003110 Colonic Neoplasms Dexamethasone 7.5715824018
MESH:D003110 Colonic Neoplasms Fluorouracil 7.5718772588 16510598 17169374 15001691 17018589 17725105 17016597 17287894 17172411 16340194
MESH:D003110 Colonic Neoplasms Indomethacin 7.5715637740 15963497 11260862 15625704 15786552 15936596
MESH:D015179 Colorectal Neoplasms decitabine 3.2918981723
MESH:D015179 Colorectal Neoplasms Fluorouracil 3.2917094418 16391804 15148649 18448328 17401013 20501625 16331619 16303861 17594712 18802399 17016601 18383874 14970324 16282729 15289873 17695437 17255274 16524972 18949393 17454858 18288408 18509181
MESH:D015179 Colorectal Neoplasms Indomethacin 3.2918059344 17054584 11197048 12606626
MESH:D000013 Congenital Abnormalities 4-amino-2,6-dinitrotoluene 8.0215095906
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 8.0214669216 17141729
MESH:D018352 Coronavirus Infections Indomethacin 5.2917302372
MESH:D019465 Craniofacial Abnormalities Dexamethasone 2.4717728286
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 2.4710048152 20055451 15322242
MESH:D007644 Darier Disease Fluorouracil 4.3716733453
MESH:D017449 Dermatitis, Allergic Contact 4,4'-diaminodiphenylmethane 9.398156756 11906362 14531868 8970840 18759878 11298694 2524372 12868966
MESH:D017449 Dermatitis, Allergic Contact cobaltous chloride 9.3916823706 11298694 15059100
MESH:D017449 Dermatitis, Allergic Contact Dexamethasone 9.3912438553
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.2218249437
MESH:D003877 Dermatitis, Contact 4,4'-diaminodiphenylmethane 3.112952479 3621924
MESH:D003920 Diabetes Mellitus rosiglitazone 3.9517446233
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 6.4620387270
MESH:D003924 Diabetes Mellitus, Type 2 rosiglitazone 6.4612642470
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 6.4617107852
MESH:D003967 Diarrhea Dexamethasone 6.967237001
MESH:D003967 Diarrhea Indomethacin 6.967907874 7237001
MESH:D056486 Drug-Induced Liver Injury 4,4'-diaminodiphenylmethane 13.4111289319 18289764 9653073 1440618 6482804 9328219 9022650 7440962 8291058 16192314 18692083 18648102 6679447
MESH:D056486 Drug-Induced Liver Injury 4-amino-2,6-dinitrotoluene 13.4121346803
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 13.4118071297 19164858 14550746 16081117 19739265 2444490 16781746 16109766 14725611 11834606 11461765 11421492 11739529 16227642 19416960 17522070 11287661 19923254 11529661 12594235 12705907 17906064 10915739 12958197 11743745 16177239 16485898 15619225 10774834 15968718 12153990 19420014 12540782 19085960 12392966 14986274 10663392 16393943 18713872 19370779 17562736
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 13.417179309 6623471 10092053 3786805 6884620 11566570 15027814 15998439 21278145 7120509 4309450 19085960 10915739 16177239 2869522 16227642 17522070 3732212 19336974 9327722 7440962 15968718
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 13.4119107877
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 13.4120420201
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 3.6719426721
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.4511462148
MESH:D004374 Ductus Arteriosus, Patent Indomethacin 4.7318446180 16326151 12774134 16133044 17190690 18043480
MESH:D004381 Duodenal Ulcer Indomethacin 3.7417151854 11595431 16699067 11595415 17351913 17202747 11535926 17045617 17329845 10671773 11991626
MESH:D050171 Dyslipidemias marker/mechanism
MESH:D050171 Dyslipidemias Dietary Fats 7.9418367378
MESH:D050171 Dyslipidemias Fenofibrate 7.9416707586
MESH:D004417 Dyspnea Oxygen 4.4120016425
MESH:D004421 Dystonia Phenobarbital 3.621851702
MESH:D004485 Eczema Dexamethasone 4.0612438553
MESH:D004487 Edema Dexamethasone 22.2319703484
MESH:D004487 Edema Indomethacin 22.2319703484 16100529 7990266 7907874 10653021 8273558 8985016
MESH:D004487 Edema perfluorooctanoic acid 22.2317259670 12083418
MESH:D004487 Edema pirinixic acid 22.2312083418
MESH:D004487 Edema rosiglitazone 22.2312083418
MESH:D004487 Edema Tetrachlorodibenzodioxin 22.2312711302 11000095
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 3.4715322242 16714409 18230668
MESH:D004701 Endocrine Gland Neoplasms decitabine 4.6919294695
MESH:D016889 Endometrial Neoplasms Fenofibrate 3.8116569247
MESH:D004715 Endometriosis Indomethacin 7.8715652904
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 7.8710568697 9294722
MESH:D019446 Endotoxemia Indomethacin 4.0818509659
MESH:D004751 Enteritis Indomethacin 4.3217763956 10567023 16328016
MESH:D020345 Enterocolitis, Necrotizing Indomethacin 4.5717980183
MESH:D004802 Eosinophilia Indomethacin 3.6511298111
MESH:D004831 Epilepsies, Myoclonic Phenobarbital 3.703659116
MESH:D004828 Epilepsies, Partial Phenobarbital 3.4511558140 3922381
MESH:D004827 Epilepsy Phenobarbital 2.6720417680
MESH:D004832 Epilepsy, Absence Phenobarbital 3.196401628
MESH:D017029 Epilepsy, Complex Partial Phenobarbital 3.847750514
MESH:D004830 Epilepsy, Tonic-Clonic Phenobarbital 3.603659116
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 4.6916302075
MESH:D004938 Esophageal Neoplasms 4,4'-diaminodiphenylmethane 9.383581430
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 9.3816530937
MESH:D004938 Esophageal Neoplasms Fluorouracil 9.3815173087 16785472 16337965 16481741 17638652
MESH:D004938 Esophageal Neoplasms Indomethacin 9.3811005569
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 2.7011564622
MESH:D005234 Fatty Liver Carbon Tetrachloride 20.7017595544 19224547 16045604 61145 15959796 12631006 16239168 12795759
MESH:D005234 Fatty Liver Dietary Fats 20.7018296743 19004024 17967931 19551842
MESH:D005234 Fatty Liver Diethylnitrosamine 20.7020387270 21071580
MESH:D005234 Fatty Liver pirinixic acid 20.7020131406 19236843
MESH:D005234 Fatty Liver rosiglitazone 20.7019196556
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.0511858732
MESH:D005334 Fever Indomethacin 3.7611852909 10431976 17627676
MESH:D005350 Fibroma 4,4'-diaminodiphenylmethane 4.596705139
MESH:D005354 Fibrosarcoma Indomethacin 10.8110962813
MESH:D005354 Fibrosarcoma Methylnitrosourea 10.8111555667
MESH:D005355 Fibrosis Carbon Tetrachloride 17.8218705752
MESH:D005355 Fibrosis Dietary Fats 17.8218296743
MESH:D005355 Fibrosis Indomethacin 17.8217994277
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 17.8220067830
MESH:D005499 Folliculitis Indomethacin 4.7411298111
MESH:D005739 Gas Poisoning Oxygen 4.7920016425
MESH:D005756 Gastritis Acetaminophen 9.7316983495
MESH:D005756 Gastritis Indomethacin 9.7315046732
MESH:D005909 Glioblastoma Indomethacin 6.7312870263
MESH:D005909 Glioblastoma Manganese 6.7317043766
MESH:D005910 Glioma Fluorouracil 9.0316145905
MESH:D005910 Glioma Indomethacin 9.0316487511 18371953
MESH:D005910 Glioma Methylnitrosourea 9.039825942
MESH:D005923 Glomerulosclerosis, Focal Segmental Indomethacin 3.9511849393
MESH:D006042 Goiter 4,4'-diaminodiphenylmethane 3.657505956
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.1710696789
MESH:D006073 Gout Indomethacin 4.9311248219
MESH:D006258 Head and Neck Neoplasms decitabine 11.3919215824
MESH:D006258 Head and Neck Neoplasms Fluorouracil 11.3918337622 15162350 15102660
MESH:D006258 Head and Neck Neoplasms Indomethacin 11.3915482327
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 5.6820471113
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 5.6811294989 10048152
MESH:D006333 Heart Failure pirinixic acid 2.2820558911
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 2.9611000095
MESH:D006501 Hepatic Encephalopathy Indomethacin 4.1915633222
MESH:D006505 Hepatitis 4,4'-diaminodiphenylmethane 7.916705139
MESH:D006505 Hepatitis Carbon Tetrachloride 7.9119110552 19900420
MESH:D019698 Hepatitis C, Chronic Indomethacin 4.2815135802
MESH:D006529 Hepatomegaly perfluorooctanoic acid 17.343609246
MESH:D006529 Hepatomegaly Phenobarbital 17.3416109766
MESH:D006529 Hepatomegaly pirinixic acid 17.3418467677 19772884 16221962 19176532
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 17.3415340226 12621046 16120746
MESH:D006548 Hernia, Diaphragmatic Dexamethasone 2.917520565
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.6216959395 8697196 18606429 16354765 15340226
MESH:D006930 Hyperalgesia Acetaminophen 16.0216870215
MESH:D006930 Hyperalgesia Indomethacin 16.0212727271
MESH:D006930 Hyperalgesia perfluorooctanoic acid 16.0212083418
MESH:D006930 Hyperalgesia rosiglitazone 16.0212083418
MESH:D034321 Hyperamylasemia Indomethacin 5.2917883296
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 4.1116899240
MESH:D006937 Hypercholesterolemia Dietary Fats 3.2221332399
MESH:D006940 Hyperemia Indomethacin 4.5912524144
MESH:D006943 Hyperglycemia pirinixic acid 2.8220558911
MESH:D006949 Hyperlipidemias Dietary Fats 8.0621332399
MESH:D006949 Hyperlipidemias Indomethacin 8.0617546600
MESH:D006965 Hyperplasia 4,4'-diaminodiphenylmethane 3.5315034207
MESH:D006968 Hypersensitivity, Delayed Corn Oil 5.3811484837
MESH:D006973 Hypertension Cobalt 11.0517039479
MESH:D006973 Hypertension Dexamethasone 11.0517042910
MESH:D006973 Hypertension Phenylephrine 11.0512717712 8949925
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 11.0518670907 18850075
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 3.6815338365
MESH:D015228 Hypertriglyceridemia Triglycerides 5.4716238453 16979400
MESH:D006984 Hypertrophy Phenylephrine 4.1812791704 18502941
MESH:D007077 Ileal Diseases 1-Methyl-3-isobutylxanthine 11.2918306037
MESH:D007077 Ileal Diseases Indomethacin 11.2918306037 10574470
MESH:D007079 Ileitis Indomethacin 4.9310651667 10647630 16133968
MESH:D007235 Infant, Premature, Diseases Indomethacin 4.9416133044
MESH:D007248 Infertility, Male decitabine 6.2617581917
MESH:D007248 Infertility, Male Methylnitrosourea 6.267193160
MESH:D007249 Inflammation Dexamethasone 20.748960868 11099482
MESH:D007249 Inflammation Dietary Fats 20.7420412841
MESH:D007249 Inflammation Diethylnitrosamine 20.7418785209
MESH:D007249 Inflammation Indomethacin 20.7412568917 3291741 7812673
MESH:D007249 Inflammation perfluorooctanoic acid 20.7412083418
MESH:D007249 Inflammation rosiglitazone 20.7412083418
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 20.7412200463 12878042
MESH:D007333 Insulin Resistance Dietary Fats 10.7911836018 18457598
MESH:D007333 Insulin Resistance pirinixic acid 10.7916306350
MESH:D007333 Insulin Resistance rosiglitazone 10.7916306350
MESH:D007410 Intestinal Diseases Indomethacin 3.9215831440 11713966 11686837 17329856 18236018 17994277 11855677 10210152 15610444
MESH:D019586 Intracranial Hypertension Indomethacin 4.9415241188
MESH:D007565 Jaundice 4,4'-diaminodiphenylmethane 4.598074119 9022650
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 2.9616580747
MESH:D007579 Jejunal Diseases 1-Methyl-3-isobutylxanthine 11.2918306037
MESH:D007579 Jejunal Diseases Indomethacin 11.2910574470 18306037 16133968
MESH:D007674 Kidney Diseases Acetaminophen 5.3115629191 12587719
MESH:D007674 Kidney Diseases Indomethacin 5.3117190690
MESH:D007680 Kidney Neoplasms 4,4'-diaminodiphenylmethane 6.366582329
MESH:D007680 Kidney Neoplasms Fluorouracil 6.3616985049
MESH:D016773 Leishmaniasis, Cutaneous Indomethacin 3.5711703811 10320625 12228301
MESH:D007938 Leukemia decitabine 2.8618980019 19235587
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive Indomethacin 3.6116572323 15631656 10785260
MESH:D007951 Leukemia, Myeloid decitabine 3.6318454857 17236224 19117987
MESH:D015470 Leukemia, Myeloid, Acute decitabine 3.8817679729 19010910 18460780 19387464 18206229 18704418
MESH:D015470 Leukemia, Myeloid, Acute Indomethacin 3.8818360721
MESH:D015477 Leukemia, Myelomonocytic, Chronic decitabine 5.0318055864
MESH:D007964 Leukocytosis Indomethacin 4.9416537180
MESH:D007969 Leukomalacia, Periventricular Indomethacin 5.2917980183
MESH:D007984 Leydig Cell Tumor perfluorooctanoic acid 4.818812269
MESH:D017880 Limb Deformities, Congenital Methylnitrosourea 3.9015526292
MESH:D008101 Liver Abscess, Amebic Indomethacin 5.2911479899
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 13.7821278145 16943688 17157831 11903743 16239168 17174718 17334410 11408273 16221502
MESH:D008103 Liver Cirrhosis Dietary Fats 13.7818296743
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 13.7820032147 19638242 18665156 18407596 18522880
MESH:D008103 Liver Cirrhosis Phenobarbital 13.7821047994
MESH:D008105 Liver Cirrhosis, Biliary 4,4'-diaminodiphenylmethane 2.9315034207 9327722
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 9.9515876570 12586293 18429990 16011737 18205269 15931870 13678700 14724832 16192424 18420326 12445421 14748882 15818738 17944888 10355542 16033810 12667390 17869086 18339082 12741479 18187930 17565644 18418968 15057751 17766677 18395095 12898905 18317297 18412020 20821823 15362042 17481882 18156304 17922224 16027843 15996030 17631135 18481824 17525996 12609069 17640975 15650968 17721639 12649538 18279442 18472332 18395914 18166357 12632512 18705752 17557913 15959796 15123356 16097048 12546737 18277467 12632514 16116963 17698563 17900296 18210741 18263696 18054572 16136751 16248980 18472094 17714472 12958196 16015684 14716833 12445418 15052691 17805973 15893842 16638106 11481614 17708605 17976157 18376398 18251166 15673190 15370692 14512876 17823541 15338365 12666154 14716496 17761835 15925388 15730626 18006644 14620537 12389079
MESH:D008106 Liver Cirrhosis, Experimental Dexamethasone 9.9516718785
MESH:D008106 Liver Cirrhosis, Experimental Fenofibrate 9.9515474484
MESH:D008106 Liver Cirrhosis, Experimental Indomethacin 9.9518194892
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 9.9515474484
MESH:D008106 Liver Cirrhosis, Experimental rosiglitazone 9.9517347453 15980055
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 9.9512878042
MESH:D008107 Liver Diseases Acetaminophen 8.3311587558 19784758 12587719 12969438 16610002 16611625 19014921 19460945
MESH:D008107 Liver Diseases Carbon Tetrachloride 8.3316964402 16246199 17285989 15720792 15830285
MESH:D008107 Liver Diseases Diethylnitrosamine 8.3317034775
MESH:D008107 Liver Diseases Phenobarbital 8.3319363144
MESH:D017093 Liver Failure Carbon Tetrachloride 3.7515123358
MESH:D017114 Liver Failure, Acute Acetaminophen 8.2016871587 17185352
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 8.2016899240 14706259
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 30.6320195826 21137059
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 30.6319294768
MESH:D008113 Liver Neoplasms Clofibric Acid 30.6317602206
MESH:D008113 Liver Neoplasms Diethylnitrosamine 30.632422723 12771043 19090486 20583210 19850985 20492335 18978307 10737359 20501860 19427195 19642983 19499222 15885732 21047994 21167192 16942905 2862719 19073162 19551842 9163691 20434301 21278145 21071580 19255062 20118626 19833225 20452335 19690152 18754104 20405173 18977376 19638242 18644402 19996281 15175105 12112319 19294768 20137499 19426721 19256749 19254457 19812893 20101389 18648771
MESH:D008113 Liver Neoplasms Fenofibrate 30.6318978307
MESH:D008113 Liver Neoplasms Fluorouracil 30.6315113037 16603448 18383874 17045692
MESH:D008113 Liver Neoplasms perfluorooctanoic acid 30.6318709148 14757943
MESH:D008113 Liver Neoplasms Phenobarbital 30.6319482888 8742319 19812893 21047994 19073162 15975961
MESH:D008113 Liver Neoplasms pirinixic acid 30.6320007298 15890375 16377806
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 30.6316984957
MESH:D008114 Liver Neoplasms, Experimental 4,4'-diaminodiphenylmethane 19.903712494 1399818 598648 6587162
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 19.9012014681 15583823
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 19.9019519916 18775883 19126423 18544905 18282651 18079962 18253720 16267830 17942915 18308698 3124819 19009564 18164116 19539802 18093689 9362446 17174075 19004024 17854601 21159647 2563599 16842330
MESH:D008114 Liver Neoplasms, Experimental Fenofibrate 19.9018253720 18775883
MESH:D008114 Liver Neoplasms, Experimental Phenobarbital 19.9017172636 2563599 18308698 6150874 1399818
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 19.9012151625
MESH:D038061 Lower Extremity Deformities, Congenital Methylnitrosourea 5.0516080182
MESH:D008171 Lung Diseases Ozone 3.0919066396 8266340
MESH:D008173 Lung Diseases, Obstructive Cobalt 5.456434250
MESH:D055370 Lung Injury Oxygen 8.0718339021
MESH:D055370 Lung Injury Ozone 8.0720417186
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 11.8818520028 18569708 17053015 18816296 20464547 6695378 20869020 20135361 20064080
MESH:D008175 Lung Neoplasms Dexamethasone 11.8815824018 11195469
MESH:D008175 Lung Neoplasms Diethylnitrosamine 11.8820970405 20512841 21163286 6695378
MESH:D008175 Lung Neoplasms Fluorouracil 11.8815246190
MESH:D008175 Lung Neoplasms Indomethacin 11.8811497255 16537180 11053908
MESH:D008175 Lung Neoplasms Methylnitrosourea 11.8818062963
MESH:D008175 Lung Neoplasms Ozone 11.887614698 8597069
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 11.8819555203 11884234
MESH:D008178 Lupus Erythematosus, Cutaneous Fluorouracil 4.3715086387
MESH:D008207 Lymphatic Metastasis therapeutic 17130448
MESH:D008223 Lymphoma decitabine 6.9319470736
MESH:D008223 Lymphoma Methylnitrosourea 6.9311418001 16257854
MESH:D016393 Lymphoma, B-Cell Methylnitrosourea 4.3914633661
MESH:D008325 Mammary Neoplasms, Experimental Methylnitrosourea 5.7310838139 15113128 12931682 11807958 16619500 11751437 14633655 15313902 10767621 16944150 19196723 15688392 16051031 14999141 17020996 17131329 16827153
MESH:D008325 Mammary Neoplasms, Experimental rosiglitazone 5.7316827153
MESH:D020149 Manganese Poisoning Manganese 5.0916551646 16568477 19453300
MESH:D008545 Melanoma decitabine 3.5616505122 17785578
MESH:D008545 Melanoma Glucose 3.5614993021
MESH:D008546 Melanoma, Experimental Acetaminophen 3.1619513568
MESH:D024821 Metabolic Syndrome X rosiglitazone 4.0317261469
MESH:D008679 Metaplasia Ozone 4.6810496685
MESH:D008881 Migraine Disorders Indomethacin 3.3811903285
MESH:D020326 Migraine without Aura Cyclic AMP 4.7611304026
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 12.5616381670
MESH:D009062 Mouth Neoplasms Fluorouracil 12.5616757204 18986760
MESH:D009062 Mouth Neoplasms Indomethacin 12.5612636206
MESH:D009069 Movement Disorders Manganese 4.6216551646
MESH:D009101 Multiple Myeloma decitabine 6.5318172295
MESH:D009101 Multiple Myeloma Dexamethasone 6.5316118317 15744524 15867202
MESH:D009135 Muscular Diseases Bezafibrate 9.3716239165
MESH:D009135 Muscular Diseases pirinixic acid 9.3716239165
MESH:D009190 Myelodysplastic Syndromes decitabine 6.8219010910 19157545 18608210 16882708
MESH:D009190 Myelodysplastic Syndromes Dexamethasone 6.829809623
MESH:D009203 Myocardial Infarction pirinixic acid 1.9619151258
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 2.6912213967
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 2.6316411023
MESH:D020191 Myoclonic Epilepsies, Progressive Phenobarbital 4.0617484760
MESH:D009361 Neoplasm Invasiveness therapeutic 17130448
MESH:D009362 Neoplasm Metastasis therapeutic 17130448
MESH:D009362 Neoplasm Metastasis 4,4'-diaminodiphenylmethane 8.493581430
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 8.499029167 3581430
MESH:D009362 Neoplasm Metastasis Indomethacin 8.4911239499 11053908 16537180
MESH:D009369 Neoplasms Benzo(a)pyrene 13.4111141357
MESH:D009369 Neoplasms decitabine 13.4119470736 17925555 19116145
MESH:D009369 Neoplasms Fluorouracil 13.4118600527 16928823 18239605
MESH:D009369 Neoplasms Methylnitrosourea 13.4115533788
MESH:D009369 Neoplasms pirinixic acid 13.4117405874
MESH:D009374 Neoplasms, Experimental Indomethacin 8.2210663608 15625704
MESH:D009374 Neoplasms, Experimental Methylnitrosourea 8.2212696579
MESH:D009410 Nerve Degeneration Manganese 3.9616551646
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 2.8214600291
MESH:D009436 Neural Tube Defects 4,4'-diaminodiphenylmethane 2.646679447
MESH:D009442 Neurilemmoma Methylnitrosourea 5.0711555667
MESH:D019636 Neurodegenerative Diseases Acetaminophen 12.1018514411
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 12.1020387270
MESH:D019636 Neurodegenerative Diseases Indomethacin 12.1012349958
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 4.6920387270
MESH:D020258 Neurotoxicity Syndromes Fluorouracil 3.1516436463
MESH:D052556 Niemann-Pick Disease, Type C perfluorooctanoic acid 4.549802331
MESH:D009765 Obesity Dietary Fats 4.0419632207 20518802 18674790 18457598 17217161 20132043 21332399 16723640 11836018
MESH:D009765 Obesity pirinixic acid 4.0420558911
MESH:D007752 Obstetric Labor, Premature Indomethacin 4.746374098
MESH:D009784 Occupational Diseases 4,4'-diaminodiphenylmethane 7.926482804 4026338
MESH:D009784 Occupational Diseases 4-amino-2,6-dinitrotoluene 7.9214694615
MESH:D009902 Optic Neuritis 4,4'-diaminodiphenylmethane 4.593988306
MESH:D010003 Osteoarthritis Indomethacin 3.417009135
MESH:D010018 Osteomalacia Phenobarbital 3.9417016548
MESH:D010051 Ovarian Neoplasms decitabine 2.5119259094 19331143
MESH:D010146 Pain Acetaminophen 5.6816870215
MESH:D010146 Pain Indomethacin 5.6817627676 13679232 3291741 17440234
MESH:D010149 Pain, Postoperative Indomethacin 4.2512538197 18702446
MESH:D010190 Pancreatic Neoplasms decitabine 14.5719294695
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 14.5716540662
MESH:D010190 Pancreatic Neoplasms Fluorouracil 14.5719003803 16929163 15113037 16500647
MESH:D010190 Pancreatic Neoplasms Methylnitrosourea 14.5716965848
MESH:D010190 Pancreatic Neoplasms Phenobarbital 14.5716965848
MESH:D010195 Pancreatitis Fatty Acids, Nonesterified 8.0318983441
MESH:D010195 Pancreatitis Indomethacin 8.0315028970 17883296
MESH:D010212 Papilloma 4,4'-diaminodiphenylmethane 3.087296757
MESH:D010257 Paraneoplastic Syndromes Indomethacin 5.2916537180
MESH:D010300 Parkinson Disease Manganese 3.2111181820
MESH:D020734 Parkinsonian Disorders Indomethacin 8.3212349958
MESH:D020734 Parkinsonian Disorders Manganese 8.3216140633
MESH:D051302 Paroxysmal Hemicrania Indomethacin 5.2911903285
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 3.8212520081
MESH:D010437 Peptic Ulcer Indomethacin 4.7311148446
MESH:D010518 Periodontitis Indomethacin 4.4917225004
MESH:D010538 Peritonitis Ozone 3.7216369182
MESH:D010787 Photosensitivity Disorders 4,4'-diaminodiphenylmethane 4.046228378
MESH:D011014 Pneumonia Ozone 3.9818381685 18007984 18929643
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.1618163543
MESH:D011230 Precancerous Conditions Corn Oil 13.4814668109
MESH:D011230 Precancerous Conditions Diethylnitrosamine 13.482563599
MESH:D011230 Precancerous Conditions Phenobarbital 13.482563599
MESH:D054198 Precursor Cell Lymphoblastic Leukemia-Lymphoma Dexamethasone 3.3021297632
MESH:D047928 Premature Birth Indomethacin 4.7217000239
MESH:D011297 Prenatal Exposure Delayed Effects perfluorooctanoic acid 8.2817132714
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 8.2811118676 11399792 11896295 11222880
MESH:D055728 Primary Myelofibrosis decitabine 4.3217616702
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 2.8217292933
MESH:D011471 Prostatic Neoplasms Fluorouracil 2.8218626508 19082440
MESH:D011471 Prostatic Neoplasms Methylnitrosourea 2.8215682402 12376480
MESH:D011507 Proteinuria Indomethacin 3.7811849393
MESH:D019310 Pseudolymphoma Phenobarbital 4.0712752131
MESH:D011658 Pulmonary Fibrosis Cobalt 3.836434250
MESH:D012004 Rectal Neoplasms Fluorouracil 3.6618286688 15538739 16160472 18722050
MESH:D015427 Reperfusion Injury pirinixic acid 2.1719058328
MESH:D012128 Respiratory Distress Syndrome, Adult Dexamethasone 8.2111700416 18379247
MESH:D012128 Respiratory Distress Syndrome, Adult Oxygen 8.2118339021 17627322
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.4418990726
MESH:D012162 Retinal Degeneration 4,4'-diaminodiphenylmethane 8.073692021
MESH:D012162 Retinal Degeneration Methylnitrosourea 8.0718172121 18155124
MESH:D012175 Retinoblastoma Methylnitrosourea 5.0711555667
MESH:D012208 Rhabdomyosarcoma decitabine 4.0219155313
MESH:D012640 Seizures Phenobarbital 2.423137016 4039156 16876388 11442880
MESH:D003294 Seizures, Febrile Phenobarbital 4.406407741
MESH:D012852 Sinusitis Phenylephrine 4.287327846
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 8.3219755658 10029692
MESH:D012878 Skin Neoplasms Glucose 8.3214993021
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 8.3216192470
MESH:D013272 Stomach Diseases Dexamethasone 8.9815472012
MESH:D013272 Stomach Diseases Indomethacin 8.9816184426 16113693 18545984 15472012 10192188 15038085 16280098 17207306 17638125 10215738 18209964 17160473 10486359
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 7.632093021 20155912
MESH:D013274 Stomach Neoplasms decitabine 7.6319037991
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 7.6318456281
MESH:D013274 Stomach Neoplasms Fluorouracil 7.6317498489 18396642 19084572 17522103 15786421 18567086 16951190 19015929 17172411 16424979
MESH:D013274 Stomach Neoplasms Indomethacin 7.6315609394
MESH:D013274 Stomach Neoplasms Methylnitrosourea 7.6316257854 18593901 15930296
MESH:D013276 Stomach Ulcer Dexamethasone 6.3515138204
MESH:D013276 Stomach Ulcer Indomethacin 6.3518193104 18299717 18181030 11523592 10878458 16169175 17977527 10750652 17657623 11145282 18209962 12787963 16934674 16150113 11595431 17135157 16631530 12467913 10423059 12498302 17895592 18543354 16755016 12500499 16397915 17654042 15138204 18237397 12077510 14567935 17918041 15255614 11906479 16252198 1323529 18726076 15104355 18087811 17627676 11729361 18431645 11595415
MESH:D013398 Sudden Infant Death Oxygen 5.1212563064
MESH:D013953 Thymus Neoplasms Methylnitrosourea 4.8111418001
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.4712697716
MESH:D013964 Thyroid Neoplasms 4,4'-diaminodiphenylmethane 28.911399818 3712494 7505956 6582329 6587162
MESH:D013964 Thyroid Neoplasms decitabine 28.9117967635
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 28.917505956
MESH:D013964 Thyroid Neoplasms Indomethacin 28.9118791128 11352223 14736730
MESH:D013964 Thyroid Neoplasms Methylnitrosourea 28.913078959 7505956
MESH:D013964 Thyroid Neoplasms N-(4-bromo-2-fluorophenyl)-6-methoxy-7-((1-methylpiperidin-4-yl)methoxy)quinazolin-4-amine 28.9116940797
MESH:D013964 Thyroid Neoplasms Phenobarbital 28.911399818
MESH:D014062 Tongue Neoplasms Fluorouracil 3.6316280240
MESH:D014456 Ulcer Indomethacin 4.4717380554 10574470
MESH:D001749 Urinary Bladder Neoplasms 4,4'-diaminodiphenylmethane 7.288074119
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 7.2817053015
MESH:D001749 Urinary Bladder Neoplasms decitabine 7.2817616700 19087683
MESH:D014581 Urticaria Acetaminophen 2.6010982225
MESH:D002583 Uterine Cervical Neoplasms Fluorouracil 3.5216803524
MESH:D014604 Uveal Neoplasms decitabine 4.4917785578
MESH:D014605 Uveitis Dexamethasone 4.391336536
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.1712125929
MESH:D014839 Vomiting Indomethacin 4.3211897121
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 3.8215886252
MESH:D015430 Weight Gain Dietary Fats 3.3916723640
Pathway ID Pathway Name
REACT:15380 Diabetes pathways
REACT:22258 Metabolism of lipids and lipoproteins
KEGG:03320 PPAR signaling pathway
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA24797
    • No data
    Releated disease ID Related disease Name
    PA443796Coronary Artery Disease
    No data
    Drug Bank Top

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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