AutismKB 2.0

Annotation Detail for DBR1


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Basic Information Top
Gene Symbol:DBR1 ( - )
Gene Full Name: debranching enzyme homolog 1 (S. cerevisiae)
Band: 3q22.3
Quick LinksEntrez ID:51163; OMIM: 607024; Uniprot ID:DBR1_HUMAN; ENSEMBL ID: ENSG00000138231; HGNC ID: 15594
Relate to Another Database: SFARIGene; denovo-db
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Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D006710 Homocysteine Homocysteine results in decreased expression of DBR1 mRNAdecreases expression 17326132
C010327 salinomycin salinomycin results in decreased expression of DBR1 mRNAdecreases expression 19682730
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D001321 Autistic Disorder Homocysteine 3.0116297937 20468076
MESH:D001943 Breast Neoplasms salinomycin 3.3019682730
MESH:D003324 Coronary Artery Disease Homocysteine 3.8816379339
MESH:D017889 Exfoliation Syndrome Homocysteine 6.5916504073
MESH:D005901 Glaucoma Homocysteine 5.8916504073
MESH:D006330 Heart Defects, Congenital Homocysteine 4.2219638421
MESH:D020138 Hyperhomocysteinemia Homocysteine 5.1717292331 18234410 17369066
MESH:D008325 Mammary Neoplasms, Experimental salinomycin 4.0519682730
MESH:D008591 Meningomyelocele Homocysteine 6.3016602021
MESH:D009203 Myocardial Infarction Homocysteine 3.8717412321
MESH:D010300 Parkinson Disease Homocysteine 3.7116275827
MESH:D012559 Schizophrenia Homocysteine 3.1516641680
No data
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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