AutismKB 2.0

Annotation Detail for NAGPA


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Basic Information Top
Gene Symbol:NAGPA ( APAA,UCE )
Gene Full Name: N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
Band: 16p13.3
Quick LinksEntrez ID:51172; OMIM: 607985; Uniprot ID:NAGPA_HUMAN; ENSEMBL ID: ENSG00000103174; HGNC ID: 17378
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene affects the expression of NAGPA mRNAaffects expression 21346803
D000082 Acetaminophen Acetaminophen affects the expression of NAGPA mRNAaffects expression 17562736
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000799 Angioedema Acetaminophen 4.9110982225
MESH:D001321 Autistic Disorder Acetaminophen 1.3918445737
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 2.9916705839
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 2.993084413
MESH:D002386 Cataract Acetaminophen 2.8310977129
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 3.096135515
MESH:D003490 Cyanosis 2,6-dinitrotoluene 4.7818551238
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 4.0821346803 18551238
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 4.0819420014 11529661 19923254 11461765 19370779 15968718 2444490 12705907 16485898 16227642 15619225 17906064 10663392 10915739 17562736 11287661 10774834 14986274 12392966 11834606 19164858 16177239 12153990 14725611 16081117 12958197 12594235 17522070 18713872 14550746 16393943 19085960 16109766 18071297 11739529 12540782 11743745 19416960 11421492 16781746 19739265
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 5.1719426721
MESH:D005756 Gastritis Acetaminophen 4.7416983495
MESH:D006930 Hyperalgesia Acetaminophen 3.1116870215
MESH:D007674 Kidney Diseases Acetaminophen 2.4412587719 15629191
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 3.4116705839
MESH:D008107 Liver Diseases Acetaminophen 1.7119460945 11587558 19014921 16611625 12969438 16610002 19784758 12587719
MESH:D017114 Liver Failure, Acute Acetaminophen 3.7417185352 16871587
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 2.297678174
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 2.822876784 2876786 6135515
MESH:D008546 Melanoma, Experimental Acetaminophen 4.3319513568
MESH:D009336 Necrosis 2,6-dinitrotoluene 4.757678174 18551238
MESH:D019636 Neurodegenerative Diseases Acetaminophen 3.3118514411
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 3.9416049721
MESH:D010146 Pain Acetaminophen 2.8216870215
MESH:D012640 Seizures 2,6-dinitrotoluene 2.8518551238
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 2.4316049721
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 5.2010091137
MESH:D014581 Urticaria Acetaminophen 3.5810982225
Pathway ID Pathway Name
KEGG:04142 Lysosome
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA134940049
    • No data
    Releated disease ID Related disease Name
    PA445757Stuttering
    No data
    Drug Bank Top
    Drugbank ID Action Drug Name Description
    DB00141 - N-Acetyl-D-glucosamine Dietary supplement;Micronutrient
    No data
    No data
    No data

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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