AutismKB 2.0

Annotation Detail for PCOLCE


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:PCOLCE ( PCPE,PCPE1 )
Gene Full Name: procollagen C-endopeptidase enhancer
Band: 7q22.1
Quick LinksEntrez ID:5118; OMIM: 600270; Uniprot ID:PCOC1_HUMAN; ENSEMBL ID: ENSG00000106333; HGNC ID: 8738
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C000188 alachlor alachlor results in increased expression of PCOLCE mRNAincreases expression 12419858
D019386 Alendronate Alendronate affects the expression of PCOLCE mRNAaffects expression 16079270
D000643 Ammonium Chloride Ammonium Chloride affects the expression of PCOLCE mRNAaffects expression 16483693
C006632 arsenic trioxide arsenic trioxide results in decreased expression of PCOLCE mRNAdecreases expression 20458559
D019324 beta-Naphthoflavone [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of PCOLCE mRNAaffects cotreatment|increases expression 18164116
D020122 tert-Butylhydroperoxide tert-Butylhydroperoxide results in decreased expression of PCOLCE mRNAdecreases expression 15336504
D002251 Carbon Tetrachloride Carbon Tetrachloride affects the expression of PCOLCE mRNAaffects expression 17484886
D002251 Carbon Tetrachloride Carbon Tetrachloride results in increased expression of PCOLCE mRNAincreases expression 16239168
D002330 Carmustine Carmustine results in decreased expression of PCOLCE mRNAdecreases expression 15980968
D002995 Clofibric Acid [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of PCOLCE mRNAaffects cotreatment|affects expression 17602206
D004041 Dietary Fats Dietary Fats results in increased expression of PCOLCE mRNAincreases expression 18042831
D004052 Diethylnitrosamine [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of PCOLCE mRNAaffects cotreatment|increases expression 18164116
D004052 Diethylnitrosamine [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of PCOLCE mRNAaffects cotreatment|affects expression 17602206
D004997 Ethinyl Estradiol [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in decreased expression of PCOLCE mRNAaffects cotreatment|decreases expression 17942748
D004997 Ethinyl Estradiol Ethinyl Estradiol affects the expression of PCOLCE mRNAaffects expression 16079270
C010176 halofuginone halofuginone results in increased expression of PCOLCE mRNAincreases expression 17180598
D017239 Paclitaxel Paclitaxel results in increased expression of PCOLCE mRNAincreases expression 19682730
C041786 palm oil palm oil results in increased expression of PCOLCE mRNAincreases expression 18042831
D020849 Raloxifene Raloxifene affects the expression of PCOLCE mRNAaffects expression 16079270
D020849 Raloxifene Raloxifene results in increased expression of PCOLCE mRNAincreases expression 15576828
D012643 Selenium Selenium results in increased expression of PCOLCE mRNAincreases expression 19244175
C017947 sodium arsenite sodium arsenite results in decreased expression of PCOLCE mRNAdecreases expression 18812580
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in decreased expression of PCOLCE mRNAaffects cotreatment|decreases expression 17942748
D013755 Tetradecanoylphorbol Acetate [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of PCOLCE mRNAaffects cotreatment|affects expression 16979875
D014212 Tretinoin Tretinoin results in decreased expression of PCOLCE mRNAdecreases expression 16604517
D014810 Vitamin E Vitamin E results in increased expression of PCOLCE mRNAincreases expression 19244175
D015032 Zinc [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of PCOLCE mRNAaffects cotreatment|affects expression 16979875
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 2.7011752688 15322242 14514962
MESH:D000138 Acidosis Ammonium Chloride 3.4118287403
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.7917505938
MESH:D000169 Acrodermatitis Zinc 5.2516889938 17190629 17202136
MESH:D000230 Adenocarcinoma arsenic trioxide 4.1619825857 11798837
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 4.1614692618
MESH:D000236 Adenoma beta-Naphthoflavone 6.5919389873
MESH:D000236 Adenoma Diethylnitrosamine 6.596695378 10737359
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 9.5517620307 19052882 17162532 16434500 18056438 19061943
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 9.5516835633
MESH:D000310 Adrenal Gland Neoplasms sodium arsenite 4.5515276417
MESH:D018246 Adrenocortical Adenoma sodium arsenite 4.7516712894 17306315
MESH:D000382 Agricultural Workers' Diseases alachlor 4.5114769641 11874814
MESH:D000419 Albuminuria Raloxifene 4.4517451421 17308373
MESH:D000505 Alopecia Tretinoin 3.4915955085
MESH:D000544 Alzheimer Disease Raloxifene 4.3715800139
MESH:D000544 Alzheimer Disease Zinc 4.3716580781 16410023 17119284 16325427
MESH:D000740 Anemia Tetrachlorodibenzodioxin 2.8111748828
MESH:D000755 Anemia, Sickle Cell Zinc 4.7516916123
MESH:D001161 Arteriosclerosis Dietary Fats 9.4115238619
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 9.4111256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 6.9015885639
MESH:D001169 Arthritis, Experimental Tretinoin 6.9016412693
MESH:D001172 Arthritis, Rheumatoid Tretinoin 2.2316292516
MESH:D001249 Asthma Tretinoin 4.9116456186
MESH:D001249 Asthma Zinc 4.9117085522
MESH:D001471 Barrett Esophagus Tretinoin 4.2516935849
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 14.5416206674
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 14.5412125929
MESH:D001778 Blood Coagulation Disorders Tretinoin 14.5416206674 16197459
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.6415340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.6715746008
MESH:D001859 Bone Neoplasms Paclitaxel 4.4215867366
MESH:D001930 Brain Injuries Raloxifene 10.6216580743
MESH:D001930 Brain Injuries Zinc 10.6217109824
MESH:D001932 Brain Neoplasms Carmustine 4.2616187019
MESH:D001943 Breast Neoplasms Dietary Fats 2.8920435547
MESH:D001943 Breast Neoplasms Diethylnitrosamine 2.8917474063
MESH:D001943 Breast Neoplasms Paclitaxel 2.8918234424 15136595 18323546 16273361 11325840 16244791 16115903 18223236
MESH:D001943 Breast Neoplasms Raloxifene 2.8917595753 16912660 17242785 17893378 16837676 17049068 15775269 15572757 17440819 17261762 15758505 17952589
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 2.8920435547
MESH:D001943 Breast Neoplasms Tretinoin 2.8916443354 16873071 16166294
MESH:D001997 Bronchopulmonary Dysplasia Tretinoin 4.4416813970
MESH:D002051 Burkitt Lymphoma arsenic trioxide 4.1911589617
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 9.4316097048 3786805 15721981 16050911 15673190 10355542 15700767 16192424 16124888 18705752 16011737 16227642
MESH:D002252 Carbon Tetrachloride Poisoning Vitamin E 9.4316050911
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.6816835633
MESH:D018236 Carcinoma, Embryonal Tretinoin 5.0116168501
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 11.0714691202 16217749 15073043 11135700 15553829
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 11.0718788625
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 11.0711831363 18210153 18494052 16540662 16807293 19701751 16779866 16328049 20432363 10672840 18056438 16878318 17761372 17055752 20084675 19171122 20524982 20727157 17428255 17978847 3581430 16935385 19335982 16830150 18691550 19539802 16681979 16502159 19394651 19208518 17162532 17173139 20101231 18788625 10737359 20512989 19107877 20214788 19383236 20514400 19418558 16288022 20935162 16569478 3084413 17138121 19822196 18506893 18393292 19919837 20007298 19052882 18971187 18978308 18665156 16698587 21159647 19519916 18785209
MESH:D006528 Carcinoma, Hepatocellular Paclitaxel 11.0716313753
MESH:D006528 Carcinoma, Hepatocellular sodium arsenite 11.0715276417 17306315 16507464
MESH:D006528 Carcinoma, Hepatocellular Tretinoin 11.071917145
MESH:D002291 Carcinoma, Papillary arsenic trioxide 4.7219014326
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 3.9812490120
MESH:D002294 Carcinoma, Squamous Cell sodium arsenite 10.4918572023
MESH:D002294 Carcinoma, Squamous Cell Tetradecanoylphorbol Acetate 10.4918922899
MESH:D002294 Carcinoma, Squamous Cell Tretinoin 10.4916051514 16096774
MESH:D002294 Carcinoma, Squamous Cell Zinc 10.4916543248
MESH:D002295 Carcinoma, Transitional Cell Raloxifene 3.9417572228
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.2816120746 18850075 18670907
MESH:D002318 Cardiovascular Diseases Raloxifene 7.2915775269
MESH:D002318 Cardiovascular Diseases Zinc 7.2916936243
MESH:D002386 Cataract Tretinoin 3.0117460283
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 6.4317174075 21159647 7505956 2727394
MESH:D002471 Cell Transformation, Neoplastic sodium arsenite 6.4319524636 20056578
MESH:D018290 Cervical Intraepithelial Neoplasia Tretinoin 4.4416129372
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 8.8919052882
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 8.8916835633
MESH:D002779 Cholestasis Ethinyl Estradiol 2.7615861022 16105132 16919318 17681005 17110522 17333356 11677210
MESH:D002822 Choriocarcinoma Tretinoin 5.0116461808
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 5.5615340226 16354765 8697196 15668235 12621046
MESH:D002972 Cleft Palate Tretinoin 5.569407595
MESH:D003072 Cognition Disorders Raloxifene 4.4715800139
MESH:D003092 Colitis Selenium 9.0017936198
MESH:D003092 Colitis Tretinoin 9.0017035595
MESH:D015179 Colorectal Neoplasms arsenic trioxide 2.6720501625
MESH:D015179 Colorectal Neoplasms Paclitaxel 2.6718802399
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 2.9314669216 17141729
MESH:D023903 Coronary Restenosis arsenic trioxide 4.0412609071
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 7.1510525206
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 7.1515322242 20055451 10048152
MESH:D019465 Craniofacial Abnormalities Tretinoin 7.159224671 10589399 9211117 14991402 9125849 17551590 9142499 9664655 8800419 16925845
MESH:D019465 Craniofacial Abnormalities Vitamin E 7.1519769572
MESH:D019465 Craniofacial Abnormalities Zinc 7.1519302082
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 3.9515213294
MESH:D003865 Depressive Disorder, Major Raloxifene 4.0317474826
MESH:D017449 Dermatitis, Allergic Contact alachlor 4.048428444
MESH:D003920 Diabetes Mellitus Zinc 4.0716479319
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 4.0920387270
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 4.0917107852
MESH:D003928 Diabetic Nephropathies Raloxifene 3.8017308373 17451421 15920148
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 8.6016177239 15027814 15968718 7120509 19085960 6623471 2869522 6884620 17522070 19336974 10915739 10092053 9327722 7179309 21278145 3786805 4309450 16227642 15998439 3732212 11566570 7440962
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 8.6019107877
MESH:D056486 Drug-Induced Liver Injury Selenium 8.6015131321
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 8.6020420201
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.6511462148
MESH:D050171 Dyslipidemias Dietary Fats 3.3418367378
MESH:C538011 Eales disease Vitamin E 4.559068938
MESH:D004487 Edema Raloxifene 10.7815860553
MESH:D004487 Edema Tetrachlorodibenzodioxin 10.7812711302 11000095
MESH:D004487 Edema Tetradecanoylphorbol Acetate 10.7811698051 9599246 16716910 8113982 15177302 8273558 7812673
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 11.4418230668 15322242 16714409
MESH:D004489 Edema, Cardiac Tretinoin 11.4418230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 8.6212538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Raloxifene 8.6215845917
MESH:D016889 Endometrial Neoplasms Tretinoin 3.0116569247
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 2.899294722 10568697
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 4.9716302075
MESH:D004938 Esophageal Neoplasms arsenic trioxide 7.2012903497
MESH:D004938 Esophageal Neoplasms Paclitaxel 7.2016481741
MESH:D004938 Esophageal Neoplasms Zinc 7.2016543248
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 8.4611564622
MESH:D005124 Eye Abnormalities Tretinoin 8.469664655 16938888
MESH:D005234 Fatty Liver arsenic trioxide 28.9215073043
MESH:D005234 Fatty Liver Carbon Tetrachloride 28.9215959796 19224547 12631006 61145 16045604 16239168 12795759 17595544
MESH:D005234 Fatty Liver Dietary Fats 28.9218296743 19551842 19004024 17967931
MESH:D005234 Fatty Liver Diethylnitrosamine 28.9221071580 20387270
MESH:D005234 Fatty Liver Ethinyl Estradiol 28.9215345470
MESH:D005234 Fatty Liver Raloxifene 28.9217473493
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.3111858732
MESH:D005355 Fibrosis Carbon Tetrachloride 19.9118705752
MESH:D005355 Fibrosis Dietary Fats 19.9118296743
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 19.9120067830
MESH:D005355 Fibrosis Tretinoin 19.9117994277
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 4.1116904648
MESH:D005756 Gastritis Zinc 4.6517241300
MESH:D005833 Genital Neoplasms, Female sodium arsenite 4.5316452187
MESH:D005909 Glioblastoma Carmustine 7.1316187019
MESH:D005909 Glioblastoma Tretinoin 7.1317312396
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.4410696789
MESH:D006130 Growth Disorders Zinc 3.8717217573
MESH:D006258 Head and Neck Neoplasms Tretinoin 3.0816096774
MESH:D006317 Hearing Loss, Noise-Induced Tretinoin 5.0116084493
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 10.6810048152 11294989
MESH:D006330 Heart Defects, Congenital Tretinoin 10.689664655 14991402
MESH:D006330 Heart Defects, Congenital Vitamin E 10.6816080930
MESH:D006331 Heart Diseases Raloxifene 3.4311110106
MESH:D006333 Heart Failure Selenium 7.0417162251
MESH:D006333 Heart Failure Zinc 7.0417162251
MESH:D006335 Heart Injuries Zinc 5.6217074742
MESH:D016481 Helicobacter Infections Zinc 4.3917241300
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.2011000095
MESH:D006505 Hepatitis Carbon Tetrachloride 3.4519110552 19900420
MESH:D006527 Hepatolenticular Degeneration Zinc 4.5417276780
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 2.7412621046 15340226 16120746
MESH:D006548 Hernia, Diaphragmatic Vitamin E 2.6516490937 16863852
MESH:D006689 Hodgkin Disease sodium arsenite 3.0312676792
MESH:D019584 Hot Flashes Vitamin E 3.8214716179
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.8915340226 8697196 16354765 18606429 16959395
MESH:D006930 Hyperalgesia Alendronate 7.9716769263
MESH:D006930 Hyperalgesia Tretinoin 7.9716870215
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 4.3816899240
MESH:D006937 Hypercholesterolemia Dietary Fats 3.4521332399
MESH:D017681 Hypereosinophilic Syndrome Tretinoin 4.4216778211
MESH:D006949 Hyperlipidemias Dietary Fats 3.4721332399
MESH:D006965 Hyperplasia halofuginone 5.0911874485
MESH:D006973 Hypertension Raloxifene 5.0417577099 15787275
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 5.0418850075 18670907
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 3.9415338365
MESH:D007021 Hypospadias Ethinyl Estradiol 3.6616945680 16569931
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.3212013081
MESH:D007248 Infertility, Male alachlor 10.7712948887 17049205 16466525
MESH:D007248 Infertility, Male Ethinyl Estradiol 10.7717937319
MESH:D007248 Infertility, Male sodium arsenite 10.7712646999 15346721
MESH:D007249 Inflammation Dietary Fats 11.3320412841
MESH:D007249 Inflammation Diethylnitrosamine 11.3318785209
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 11.3312200463 12878042
MESH:D007249 Inflammation Tetradecanoylphorbol Acetate 11.3315177302 7812673 11698051 8273558 7562506
MESH:D007251 Influenza, Human Selenium 10.4516624496
MESH:D007251 Influenza, Human Vitamin E 10.4516624496
MESH:D007333 Insulin Resistance Dietary Fats 3.0118457598 11836018
MESH:D007410 Intestinal Diseases Tretinoin 3.6217994277
MESH:D007511 Ischemia Zinc 4.4816584753
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 9.4716580747
MESH:D007569 Jaw Abnormalities Tretinoin 9.4717551590 15992940
MESH:D007674 Kidney Diseases sodium arsenite 9.7220008137
MESH:D007674 Kidney Diseases Vitamin E 9.7212488133
MESH:D007674 Kidney Diseases Zinc 9.7216960431
MESH:D007676 Kidney Failure, Chronic Selenium 9.6216518626
MESH:D007676 Kidney Failure, Chronic Zinc 9.6216518626
MESH:D007889 Leiomyoma Raloxifene 4.3516973256
MESH:D007938 Leukemia alachlor 10.2014769641
MESH:D007938 Leukemia arsenic trioxide 10.2015070760
MESH:D007938 Leukemia Tretinoin 10.2017143497
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 3.6612560223 17077332
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 4.1516972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 3.3214633726
MESH:D007951 Leukemia, Myeloid arsenic trioxide 9.0119077051
MESH:D007951 Leukemia, Myeloid Tretinoin 9.0116932348 19285840 16482212
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 3.7917050201 16467208 19850784 16968895 20471514
MESH:D015470 Leukemia, Myeloid, Acute Tretinoin 3.7919850784 16294345 17596541
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 7.3115336539 16966277 9834237 17217047 16891316 19225113 17107899 16331271 15213294 15748426 16112521 17649720 12712474 11161223 19075265 17869043 16330433 15622746 17712046 12018890 19035177 12679006 19642359 16823087 11468182
MESH:D015473 Leukemia, Promyelocytic, Acute Tretinoin 7.3116823087 19075265 16766008 19642359 16140955 17339181 19029980 17107899 17506722 9834237 19225113 16891316 17294898 19035177 15748426 17712046 17217047 17361223 12679006 17649720 16935935 16788101 17301526 16331271 17368321
MESH:D015458 Leukemia, T-Cell arsenic trioxide 4.2016882451
MESH:D017880 Limb Deformities, Congenital Tretinoin 3.209224671
MESH:D008080 Liposarcoma Paclitaxel 4.6817353645
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 15.1316943688 16239168 11903743 17174718 17157831 11408273 17334410 16221502 21278145
MESH:D008103 Liver Cirrhosis Dietary Fats 15.1318296743
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 15.1318665156 18407596 19638242 20032147 18522880
MESH:D008103 Liver Cirrhosis halofuginone 15.1317180598
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 6.5512445418 18472094 12958196 18210741 18263696 12586293 14716833 12546737 15650968 17714472 10355542 15818738 18317297 15996030 17721639 12632514 17565644 18251166 15052691 12898905 18279442 17481882 18705752 17805973 12389079 18412020 14620537 12649538 17900296 17869086 18205269 18429990 15893842 15123356 16097048 12741479 16116963 15730626 12667390 17761835 20821823 16638106 14512876 18277467 17766677 15931870 12445421 18339082 17640975 17708605 15876570 18054572 14724832 16136751 17944888 17557913 16011737 17922224 16033810 15673190 17976157 18472332 15925388 18395914 15057751 16027843 11481614 18376398 15370692 16248980 18006644 15362042 17525996 15338365 18481824 14748882 18187930 18395095 12609069 14716496 18166357 18156304 18420326 18418968 16015684 17823541 13678700 15959796 12666154 17698563 17631135 12632512 16192424
MESH:D008106 Liver Cirrhosis, Experimental halofuginone 6.5518458672 14739098 11172339 12175628 16489207
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 6.5512878042
MESH:D008106 Liver Cirrhosis, Experimental Tretinoin 6.5516248980 18397230
MESH:D008106 Liver Cirrhosis, Experimental Vitamin E 6.5516169303
MESH:D008107 Liver Diseases Carbon Tetrachloride 3.9415830285 16246199 15720792 16964402 17285989
MESH:D008107 Liver Diseases Diethylnitrosamine 3.9417034775
MESH:D017093 Liver Failure Carbon Tetrachloride 4.0115123358
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 3.5616899240 14706259
MESH:D008113 Liver Neoplasms arsenic trioxide 21.0314682389
MESH:D008113 Liver Neoplasms beta-Naphthoflavone 21.0321295105 19389873
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 21.0319294768
MESH:D008113 Liver Neoplasms Clofibric Acid 21.0317602206
MESH:D008113 Liver Neoplasms Diethylnitrosamine 21.0319996281 19073162 19254457 19833225 20137499 15885732 15175105 19427195 18977376 2862719 18644402 21071580 19690152 19256749 19499222 20501860 21278145 9163691 21167192 10737359 18648771 20118626 12771043 18978307 18754104 20492335 19255062 19551842 20434301 19642983 20583210 2422723 19294768 20405173 19638242 19090486 19426721 19812893 20101389 20452335 19850985 21047994 12112319 16942905
MESH:D008113 Liver Neoplasms sodium arsenite 21.0316712894 15276417
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 21.0316984957
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 17.6520377131
MESH:D008114 Liver Neoplasms, Experimental beta-Naphthoflavone 17.6518164116
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 17.6515583823 12014681
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 17.6516842330 18164116 19009564 9362446 16267830 18775883 19539802 18253720 18308698 18079962 18282651 19004024 17854601 18544905 17942915 18093689 19126423 17174075 21159647 2563599 3124819 19519916
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 17.6512151625
MESH:D008133 Long QT Syndrome arsenic trioxide 3.2315213294
MESH:D008171 Lung Diseases sodium arsenite 7.1119095001
MESH:D008171 Lung Diseases Vitamin E 7.1116863852
MESH:D008175 Lung Neoplasms arsenic trioxide 8.3111798837 19825857
MESH:D008175 Lung Neoplasms Diethylnitrosamine 8.3120970405 21163286 6695378 20512841
MESH:D008175 Lung Neoplasms sodium arsenite 8.3117306315 15276417 19931552 17077188 16712894
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 8.3111884234 19555203
MESH:D008175 Lung Neoplasms Tetradecanoylphorbol Acetate 8.3111807781
MESH:D008175 Lung Neoplasms Vitamin E 8.3111062179
MESH:D008228 Lymphoma, Non-Hodgkin Paclitaxel 3.9714749477
MESH:D008325 Mammary Neoplasms, Experimental Selenium 9.5915318939
MESH:D008325 Mammary Neoplasms, Experimental Tetradecanoylphorbol Acetate 9.598985016
MESH:D008325 Mammary Neoplasms, Experimental Zinc 9.5912773700
MESH:D008527 Medulloblastoma Tretinoin 2.7317453147
MESH:D008545 Melanoma Carmustine 7.1412393984
MESH:D008545 Melanoma Paclitaxel 7.1412040289 16342250 12025231
MESH:D008545 Melanoma sodium arsenite 7.1419082730 16487513
MESH:D008545 Melanoma Tretinoin 7.1416752155
MESH:D008591 Meningomyelocele Tretinoin 4.2716940565
MESH:D008654 Mesothelioma Selenium 2.7315107826
MESH:D018200 Mixed Tumor, Mullerian Raloxifene 5.4015863610
MESH:D009101 Multiple Myeloma alachlor 16.4714769641
MESH:D009101 Multiple Myeloma arsenic trioxide 16.4715949261 19549372 19417148 11468182 14977855
MESH:D009101 Multiple Myeloma Paclitaxel 16.4714749477
MESH:D009101 Multiple Myeloma Raloxifene 16.4716497877
MESH:D009182 Mycosis Fungoides arsenic trioxide 4.5218349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 7.1116105982 16882451
MESH:D009190 Myelodysplastic Syndromes Tretinoin 7.1117596541
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 2.9012213967
MESH:D009232 Myxoma Raloxifene 5.4016343187
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 3.8116624393
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 5.799029167 3581430
MESH:D009362 Neoplasm Metastasis Paclitaxel 5.7915867366
MESH:D009369 Neoplasms sodium arsenite 4.8711559025
MESH:D009369 Neoplasms Tretinoin 4.8716946489 16594593
MESH:D009374 Neoplasms, Experimental sodium arsenite 3.5220056578
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 9.0214600291
MESH:D009421 Nervous System Malformations Tretinoin 9.029125849
MESH:D009436 Neural Tube Defects arsenic trioxide 11.5910525206
MESH:D009436 Neural Tube Defects sodium arsenite 11.5912854658
MESH:D009436 Neural Tube Defects Tretinoin 11.599142499
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 3.2220387270
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 4.9720387270
MESH:D009669 Nose Neoplasms alachlor 4.6711127290 14563481 15580706 16178123 16698726
MESH:D009765 Obesity Dietary Fats 2.2520132043 17217161 16723640 11836018 18457598 20518802 21332399 18674790 19632207
MESH:D010014 Osteolysis Paclitaxel 4.8315867366
MESH:D010024 Osteoporosis Alendronate 7.4817882678
MESH:D010024 Osteoporosis Raloxifene 7.4817882678 19059307 15775268
MESH:D015663 Osteoporosis, Postmenopausal Raloxifene 4.0815579764 17823083 17893378 15758505
MESH:D010051 Ovarian Neoplasms arsenic trioxide 10.9312452020 19769630 16624393
MESH:D010051 Ovarian Neoplasms Paclitaxel 10.9311161223
MESH:D010051 Ovarian Neoplasms sodium arsenite 10.9315276417 17306315
MESH:D010051 Ovarian Neoplasms Tretinoin 10.9316936753
MESH:D010146 Pain Tretinoin 2.7816870215
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 11.9115580305
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 11.9116540662
MESH:D010190 Pancreatic Neoplasms Tetradecanoylphorbol Acetate 11.9115976015
MESH:D010190 Pancreatic Neoplasms Tretinoin 11.9115976015
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.5411578682
MESH:D010212 Papilloma Tetradecanoylphorbol Acetate 4.1418404319 12065085 8330346 18922899
MESH:D010235 Paraganglioma arsenic trioxide 4.0219927285
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.1012520081
MESH:D010954 Plasmacytoma Selenium 4.7415087411
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.4118163543
MESH:D011230 Precancerous Conditions Diethylnitrosamine 3.422563599
MESH:D011225 Pre-Eclampsia Zinc 4.0617114810
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 3.0411222880 11118676 11399792 11896295
MESH:D011471 Prostatic Neoplasms arsenic trioxide 1.8919131511
MESH:D011471 Prostatic Neoplasms Paclitaxel 1.8917172428 17136230 16729912 16356831
MESH:D011471 Prostatic Neoplasms Raloxifene 1.8915731164 16220300 16536755
MESH:D011471 Prostatic Neoplasms sodium arsenite 1.8916039940
MESH:D011471 Prostatic Neoplasms Vitamin E 1.8915084515
MESH:D011471 Prostatic Neoplasms Zinc 1.8916700911 12429649 16517595 16606632
MESH:D011507 Proteinuria Tretinoin 3.4616636307
MESH:D011537 Pruritus Ethinyl Estradiol 3.1616919318 15861022
MESH:D011625 Pterygium Tretinoin 4.6416723453
MESH:D011693 Purpura Raloxifene 5.4015770314
MESH:D012135 Respiratory Sounds alachlor 4.8011874814
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.6918990726
MESH:D012162 Retinal Degeneration Zinc 4.0116584753
MESH:D012208 Rhabdomyosarcoma Tretinoin 3.9616116481 16283617
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 3.8116646077
MESH:D012871 Skin Diseases halofuginone 5.1911874485
MESH:D012871 Skin Diseases Vitamin E 5.1918709164
MESH:D012878 Skin Neoplasms sodium arsenite 17.1818572023 19524636
MESH:D012878 Skin Neoplasms tert-Butylhydroperoxide 17.188532709
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 17.1816192470
MESH:D012878 Skin Neoplasms Tetradecanoylphorbol Acetate 17.188330346 8985016 12065085 11807781 18404319
MESH:D012878 Skin Neoplasms Tretinoin 17.1816467112
MESH:D013088 Spermatocele Ethinyl Estradiol 3.7916709447
MESH:D016135 Spinal Dysraphism sodium arsenite 3.6812854658
MESH:D013274 Stomach Neoplasms arsenic trioxide 4.6217007042
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 4.6218456281
MESH:D013274 Stomach Neoplasms Paclitaxel 4.6218506536 18396642
MESH:D013274 Stomach Neoplasms Tretinoin 4.6217261132
MESH:D020521 Stroke Raloxifene 8.3116837676
MESH:D020521 Stroke Vitamin E 8.3116517955
MESH:D024801 Tauopathies Paclitaxel 4.6616930453
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.4811994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.0215669648
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.7512697716
MESH:D013964 Thyroid Neoplasms alachlor 16.218812207
MESH:D013964 Thyroid Neoplasms arsenic trioxide 16.2119014326
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 16.217505956
MESH:D013964 Thyroid Neoplasms Tretinoin 16.2116026305 17045167
MESH:D013978 Tibial Fractures Raloxifene 5.0619048282
MESH:D014062 Tongue Neoplasms Tretinoin 9.5316051514
MESH:D014062 Tongue Neoplasms Zinc 9.5316543248
MESH:D016171 Torsades de Pointes arsenic trioxide 3.8115213294
MESH:D014376 Tuberculosis Tretinoin 3.1316040207
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 8.0620435036 12845720 11780464 12973940
MESH:D001749 Urinary Bladder Neoplasms Raloxifene 8.0617572228
MESH:D001749 Urinary Bladder Neoplasms sodium arsenite 8.0611723127 16452187 16712894 17306315
MESH:D002583 Uterine Cervical Neoplasms sodium arsenite 8.9611813266
MESH:D002583 Uterine Cervical Neoplasms Tretinoin 8.9616129372
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 3.1514692618
MESH:D014604 Uveal Neoplasms Tretinoin 4.4616752155
MESH:D014652 Vascular Diseases sodium arsenite 4.2717056641
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.4412125929
MESH:D054556 Venous Thromboembolism Raloxifene 5.0616837676
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.4014671159 15869587
MESH:D014820 Vitiligo Tretinoin 3.9116761959
MESH:D014846 Vulvar Neoplasms Raloxifene 5.4016343187
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.1015886252
MESH:D015430 Weight Gain Dietary Fats 3.6116723640
MESH:D009396 Wilms Tumor Tretinoin 3.8416287080
No data
Pharmacogenomics Knowledge Base Top
Drug Bank Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved