Annotation Detail for RAPGEFL1
Basic Information Top
| Gene Symbol: | RAPGEFL1 ( Link-GEFII,MGC134798,MGC134799 ) |
|---|---|
| Gene Full Name: | Rap guanine nucleotide exchange factor (GEF)-like 1 |
| Band: | 17q21.1 |
| Quick Links | Entrez ID:51195; OMIM: NA; Uniprot ID:RPGFL_HUMAN; ENSEMBL ID: ENSG00000108352; HGNC ID: 17428 |
| Relate to Another Database: | SFARIGene; denovo-db |
Related Pathway Information| Chemical ID | Chemical Name | Interaction | Interaction Action | Publication |
|---|---|---|---|---|
| C014347 | decitabine | decitabine results in decreased expression of RAPGEFL1 mRNA | decreases expression | 19363521 |
| C014347 | decitabine | TP53 protein affects the reaction [decitabine results in decreased expression of RAPGEFL1 mRNA] | affects reaction|decreases expression | 19363521 |
| Disease ID | Disease Name | Direct Evidence | Inference Chemical Name | Inference Score | Publication |
|---|---|---|---|---|---|
| MESH:D001943 | Breast Neoplasms | decitabine | 2.52 | 19208741 18320071 | |
| MESH:D002294 | Carcinoma, Squamous Cell | decitabine | 2.70 | 19215824 | |
| MESH:D003110 | Colonic Neoplasms | decitabine | 2.40 | 17616700 | |
| MESH:D015179 | Colorectal Neoplasms | decitabine | 2.11 | 18981723 | |
| MESH:D004701 | Endocrine Gland Neoplasms | decitabine | 6.53 | 19294695 | |
| MESH:D006258 | Head and Neck Neoplasms | decitabine | 3.83 | 19215824 | |
| MESH:D007248 | Infertility, Male | decitabine | 3.54 | 17581917 | |
| MESH:D007938 | Leukemia | decitabine | 3.29 | 18980019 19235587 | |
| MESH:D007951 | Leukemia, Myeloid | decitabine | 4.63 | 17236224 19117987 18454857 | |
| MESH:D015470 | Leukemia, Myeloid, Acute | decitabine | 2.44 | 18460780 19387464 17679729 18704418 19010910 18206229 | |
| MESH:D015477 | Leukemia, Myelomonocytic, Chronic | decitabine | 6.88 | 18055864 | |
| MESH:D008223 | Lymphoma | decitabine | 3.80 | 19470736 | |
| MESH:D008545 | Melanoma | decitabine | 2.30 | 16505122 17785578 | |
| MESH:D009101 | Multiple Myeloma | decitabine | 3.72 | 18172295 | |
| MESH:D009190 | Myelodysplastic Syndromes | decitabine | 3.65 | 18608210 19010910 19157545 16882708 | |
| MESH:D009369 | Neoplasms | decitabine | 2.92 | 19470736 17925555 19116145 | |
| MESH:D010051 | Ovarian Neoplasms | decitabine | 2.77 | 19259094 19331143 | |
| MESH:D010190 | Pancreatic Neoplasms | decitabine | 2.91 | 19294695 | |
| MESH:D055728 | Primary Myelofibrosis | decitabine | 5.64 | 17616702 | |
| MESH:D012208 | Rhabdomyosarcoma | decitabine | 5.10 | 19155313 | |
| MESH:D013274 | Stomach Neoplasms | decitabine | 2.11 | 19037991 | |
| MESH:D013964 | Thyroid Neoplasms | decitabine | 3.75 | 17967635 | |
| MESH:D001749 | Urinary Bladder Neoplasms | decitabine | 2.88 | 19087683 17616700 | |
| MESH:D014604 | Uveal Neoplasms | decitabine | 6.33 | 17785578 |
| No data |