AutismKB 2.0

Annotation Detail for DDX47


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Basic Information Top
Gene Symbol:DDX47 ( DKFZp564O176,E4-DBP,FLJ30012,HQ0256,MSTP162,RRP3 )
Gene Full Name: DEAD (Asp-Glu-Ala-Asp) box polypeptide 47
Band: 12p13.1
Quick LinksEntrez ID:51202; OMIM: NA; Uniprot ID:DDX47_HUMAN; ENSEMBL ID: ENSG00000213782; HGNC ID: 18682
Relate to Another Database: SFARIGene; denovo-db
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Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene results in increased expression of DDX47 mRNAincreases expression 20406850
D004997 Ethinyl Estradiol Ethinyl Estradiol affects the expression of DDX47 mRNAaffects expression 17555576
D018038 Sodium Selenite Sodium Selenite results in increased expression of DDX47 mRNAincreases expression 18175754
D013629 Tamoxifen Tamoxifen affects the expression of DDX47 mRNAaffects expression 17555576
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Tamoxifen 5.2714745880
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 4.6617505938
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 1.8814692618
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 4.0211256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 2.8915885639
MESH:D001943 Breast Neoplasms Tamoxifen 2.1719244106 18629630 20135344 19410462 16273361 18815881 19059307 17893378 19103187 19155303 11161223 17440819 16818667 18351453 18425577 19189212 20859285 19084267 19066611 16202921 19288272 19142967 20065188 19221464 17242785 19189210 19289846 15565566 16873071 19011961 21152245 18855134 17261762 19487384 18984771 17049068 19200415 19115204 20005174 15668708 18997820 20544844 18821012 21138602 20390343
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 5.0719066611
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 3.1316705839
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 3.1316924424
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 4.0117572228
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 3.036135515
MESH:D002779 Cholestasis Ethinyl Estradiol 3.1717110522 17333356 15861022 16919318 11677210 16105132 17681005
MESH:D019457 Chromosome Breakage Sodium Selenite 5.3115894690
MESH:D003490 Cyanosis 2,6-dinitrotoluene 4.5818551238
MESH:D003711 Demyelinating Diseases Tamoxifen 4.9219031437
MESH:D003920 Diabetes Mellitus Sodium Selenite 4.1516285004
MESH:D003928 Diabetic Nephropathies Tamoxifen 3.8419279558
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 4.2818551238 21346803
MESH:D056486 Drug-Induced Liver Injury Sodium Selenite 4.2815131321
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 10.6812538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 10.6819031437
MESH:D016889 Endometrial Neoplasms Tamoxifen 3.2919155303 20544844 16202921 17893378
MESH:D005234 Fatty Liver Ethinyl Estradiol 9.1415345470
MESH:D005234 Fatty Liver Tamoxifen 9.1419224547 14986274
MESH:D052776 Female Urogenital Diseases Tamoxifen 3.4516709447
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 5.1614745880
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 4.8119069698
MESH:D007021 Hypospadias Ethinyl Estradiol 4.3716569931 16945680
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.9212013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 2.7317937319
MESH:D007249 Inflammation Tamoxifen 2.5319457130
MESH:D007333 Insulin Resistance Sodium Selenite 3.5214714311
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 8.5516705839
MESH:D007680 Kidney Neoplasms Tamoxifen 8.5518625569
MESH:D008064 Lipidoses Tamoxifen 3.4315342952 17567588
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 1.7518564211
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 4.967678174
MESH:D008113 Liver Neoplasms Tamoxifen 4.9616684651
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 2.772876786 6135515 2876784
MESH:D008175 Lung Neoplasms Tamoxifen 1.7418625569
MESH:D016393 Lymphoma, B-Cell Sodium Selenite 4.5214737004
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 4.3919428831
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 2.8614580682 16827153 11731420 19196722 19196723
MESH:D020149 Manganese Poisoning Tamoxifen 5.2719453300
MESH:D008545 Melanoma Tamoxifen 1.9219393235 12393984
MESH:D018328 Melanoma, Amelanotic Tamoxifen 4.8115990972
MESH:D009336 Necrosis 2,6-dinitrotoluene 4.497678174 18551238
MESH:D009362 Neoplasm Metastasis Tamoxifen 2.6719393235
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.6119410462
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 4.7219189210 19196722 19200415
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 3.8316049721
MESH:D016584 Panic Disorder Ethinyl Estradiol 4.1511578682
MESH:D011471 Prostatic Neoplasms Sodium Selenite 3.2018760546
MESH:D011471 Prostatic Neoplasms Tamoxifen 3.2015067354
MESH:D011537 Pruritus Ethinyl Estradiol 3.9415861022 16919318
MESH:D012640 Seizures 2,6-dinitrotoluene 2.7918551238
MESH:D013088 Spermatocele Ethinyl Estradiol 14.1116709447
MESH:D013088 Spermatocele Tamoxifen 14.1116709447
MESH:D013119 Spinal Cord Injuries Tamoxifen 4.6719457130
MESH:D019851 Thrombophilia Ethinyl Estradiol 4.0811994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.5215669648
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 5.4616049721
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 5.4617572228 16712894 8653321
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 4.9510091137
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 3.8014692618
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.9714671159 15869587
No data
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AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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