AutismKB 2.0

Annotation Detail for CRIM1


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Basic Information Top
Gene Symbol:CRIM1 ( MGC138194,S52 )
Gene Full Name: cysteine rich transmembrane BMP regulator 1 (chordin-like)
Band: 2p22.2
Quick LinksEntrez ID:51232; OMIM: 606189; Uniprot ID:CRIM1_HUMAN; ENSEMBL ID: ENSG00000150938; HGNC ID: 2359
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
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Desease Name
Anthropometric traits
Desease Name
Anthropometric traits
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Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C016403 2,4-dinitrotoluene 2,4-dinitrotoluene affects the expression of CRIM1 mRNAaffects expression 21346803
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene affects the expression of CRIM1 mRNAaffects expression 21346803
D000082 Acetaminophen Acetaminophen affects the expression of CRIM1 mRNAaffects expression 17562736
C006632 arsenic trioxide arsenic trioxide results in increased expression of CRIM1 mRNAincreases expression 15761015
15725085
D001564 Benzo(a)pyrene Benzo(a)pyrene results in decreased expression of CRIM1 mRNAdecreases expression 20106945
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of CRIM1 mRNAdecreases expression 19150397
D002251 Carbon Tetrachloride Carbon Tetrachloride results in increased expression of CRIM1 mRNAincreases expression 17484886
D004958 Estradiol Estradiol results in decreased expression of CRIM1 mRNAdecreases expression 20068009
D004997 Ethinyl Estradiol [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of CRIM1 mRNAaffects cotreatment|increases expression 17942748
D005472 Fluorouracil CRIM1 protein affects the susceptibility to Fluorouracilaffects response to substance 15352031
D005472 Fluorouracil Fluorouracil results in decreased expression of CRIM1 mRNAdecreases expression 16510598
D005472 Fluorouracil Fluorouracil results in increased expression of CRIM1 proteinincreases expression 15352031
C051890 irinotecan irinotecan analog results in decreased expression of CRIM1 mRNAdecreases expression 18927307
C029938 nickel sulfate nickel sulfate results in increased expression of CRIM1 mRNAincreases expression 16780908
C006253 pirinixic acid pirinixic acid results in decreased expression of CRIM1 mRNAdecreases expression 17426115
C004648 testosterone enanthate testosterone enanthate affects the expression of CRIM1 mRNAaffects expression 17440010
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of CRIM1 mRNAaffects cotreatment|increases expression 17942748
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 2.9011752688 15322242 14514962
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 4.0017505938
MESH:D055371 Acute Lung Injury nickel sulfate 9.2511954676 16100012 19131640 12718980
MESH:D055371 Acute Lung Injury pirinixic acid 9.2518653653
MESH:D000230 Adenocarcinoma arsenic trioxide 13.6211798837 19825857
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 13.6220127859 20464547
MESH:D000230 Adenocarcinoma Estradiol 13.6211473722
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 13.6214692618
MESH:D000230 Adenocarcinoma Fluorouracil 13.6217638652
MESH:D000236 Adenoma Benzo(a)pyrene 2.676695378
MESH:D018248 Adenoma, Liver Cell pirinixic acid 10.0716434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 10.0716835633
MESH:D000740 Anemia Fluorouracil 8.7717963324 16511603 15504547
MESH:D000740 Anemia Tetrachlorodibenzodioxin 8.7711748828
MESH:D000799 Angioedema Acetaminophen 3.9110982225
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 4.1219183758
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 3.5111256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 2.6815885639
MESH:D001321 Autistic Disorder Acetaminophen 1.4218445737
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 15.4616206674
MESH:D001778 Blood Coagulation Disorders pirinixic acid 15.4619483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 15.4612125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.8515340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.7815746008
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 1.9317474063 20146248
MESH:D001943 Breast Neoplasms Estradiol 1.9318497071 12948864 19861407 17289903 17018787 16675129 14630087 17261762
MESH:D001943 Breast Neoplasms Fluorouracil 1.9315136595 18608205 19217205 16595493 16557594 16110121 18357371
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 1.9320435547
MESH:D002051 Burkitt Lymphoma arsenic trioxide 4.3611589617
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 4.5116111702
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 3.8216192424 15700767 16227642 15721981 15673190 16097048 18705752 10355542 16011737 16124888 16050911 3786805
MESH:D002276 Carcinoid Tumor Fluorouracil 4.7316051944
MESH:D002277 Carcinoma Fluorouracil 8.2617121937
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 8.2616835633
MESH:D006528 Carcinoma, Hepatocellular 2,4-dinitrotoluene 14.1816705839
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 14.1816705839
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 14.183084413
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 14.1815073043 16217749 11135700 14691202 15553829
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 14.1818788625
MESH:D006528 Carcinoma, Hepatocellular Estradiol 14.1816924424
MESH:D006528 Carcinoma, Hepatocellular Fluorouracil 14.1817971768 16332177 17088986 16799960 18930000 17045692
MESH:D002291 Carcinoma, Papillary arsenic trioxide 4.9419014326
MESH:D002292 Carcinoma, Renal Cell Fluorouracil 3.0318695887
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 4.1412490120
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 4.6720419170
MESH:D002294 Carcinoma, Squamous Cell Fluorouracil 4.6716757204 18986760 17066447 16280240
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.3816120746 18670907 18850075
MESH:D002386 Cataract Acetaminophen 2.6010977129
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 11.286135515
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 11.2820889678
MESH:D002471 Cell Transformation, Neoplastic Estradiol 11.2818566989
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 3.1916835633
MESH:D002779 Cholestasis Ethinyl Estradiol 7.8117110522 16919318 15861022 17681005 17333356 16105132 11677210
MESH:D002779 Cholestasis pirinixic acid 7.8119176532
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 2.1115668235 8697196 12621046 15340226 16354765
MESH:D003110 Colonic Neoplasms Fluorouracil 3.9816510598 16340194 17725105 17172411 15001691 17016597 17018589 17169374 17287894 18772588
MESH:D003110 Colonic Neoplasms irinotecan 3.9817725105 17287894
MESH:D015179 Colorectal Neoplasms arsenic trioxide 3.5220501625
MESH:D015179 Colorectal Neoplasms Fluorouracil 3.5217695437 17594712 16524972 18288408 17454858 18949393 20501625 14970324 17401013 16391804 18802399 18448328 18509181 15289873 17094418 17016601 15148649 17255274 18383874 16282729 16303861 16331619
MESH:D015179 Colorectal Neoplasms irinotecan 3.5216391804 18259882 15273666 18509181 16303861 17159606 17454858
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 3.0814669216 17141729
MESH:D023903 Coronary Restenosis arsenic trioxide 4.2212609071
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 2.4810525206
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 2.4810048152 20055451 15322242
MESH:D003490 Cyanosis 2,4-dinitrotoluene 11.0418551238
MESH:D003490 Cyanosis 2,6-dinitrotoluene 11.0418551238
MESH:D007644 Darier Disease Fluorouracil 4.8416733453
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 4.1315213294
MESH:D017449 Dermatitis, Allergic Contact nickel sulfate 3.7111298694 16780908 16823706
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.4418249437
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 1.6717107852
MESH:D003928 Diabetic Nephropathies Estradiol 3.4419279558
MESH:D056486 Drug-Induced Liver Injury 2,4-dinitrotoluene 12.0921346803 18551238
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 12.0918551238 21346803
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 12.0918713872 16109766 11743745 16227642 11739529 11834606 19416960 10915739 16781746 18071297 14725611 16081117 11461765 11287661 17522070 19739265 17562736 17906064 19923254 19085960 14550746 15968718 16393943 16177239 15619225 12705907 10774834 12594235 16485898 14986274 19370779 2444490 12153990 11529661 12958197 12392966 12540782 10663392 19420014 19164858 11421492
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 12.0919085960 7179309 10915739 10092053 2869522 3732212 16177239 15998439 16227642 3786805 7440962 6884620 9327722 21278145 17522070 7120509 15968718 6623471 19336974 15027814 4309450 11566570
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 12.0920420201
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.1619426721
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.7811462148
MESH:D004487 Edema pirinixic acid 6.6312083418
MESH:D004487 Edema Tetrachlorodibenzodioxin 6.6311000095 12711302
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 3.9618230668 15322242 16714409
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 3.2212538720
MESH:D016889 Endometrial Neoplasms Estradiol 3.0011473722 18566989 19148513
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 3.059294722 10568697
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 10.4620426865
MESH:D004938 Esophageal Neoplasms arsenic trioxide 10.4612903497
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 10.4616530937
MESH:D004938 Esophageal Neoplasms Fluorouracil 10.4615173087 16481741 16337965 17638652 16785472
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 3.0311564622
MESH:D005234 Fatty Liver arsenic trioxide 19.0115073043
MESH:D005234 Fatty Liver Carbon Tetrachloride 19.0112795759 19224547 12631006 61145 16239168 16045604 15959796 17595544
MESH:D005234 Fatty Liver Ethinyl Estradiol 19.0115345470
MESH:D005234 Fatty Liver pirinixic acid 19.0119236843 20131406
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.5011858732
MESH:D005355 Fibrosis Carbon Tetrachloride 8.7418705752
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 8.7420067830
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 4.3016904648
MESH:D005756 Gastritis Acetaminophen 3.7416983495
MESH:D005910 Glioma Fluorouracil 2.8816145905
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.6610696789
MESH:D006258 Head and Neck Neoplasms Fluorouracil 3.4018337622 15162350 15102660
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 6.4920471113
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 6.4911294989 10048152
MESH:D006333 Heart Failure pirinixic acid 2.5520558911
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.3611000095
MESH:D006505 Hepatitis Carbon Tetrachloride 3.6319110552 19900420
MESH:D006529 Hepatomegaly pirinixic acid 8.4019772884 16221962 19176532 18467677
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 8.4015340226 12621046 16120746
MESH:D006558 Herpes Genitalis Estradiol 5.0915709030
MESH:D019247 HIV Wasting Syndrome testosterone enanthate 5.8117440010
MESH:D019584 Hot Flashes Estradiol 3.8117088409
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 4.1115340226 16959395 8697196 18606429 16354765
MESH:D006930 Hyperalgesia Acetaminophen 2.7216870215
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 4.5816899240
MESH:D006943 Hyperglycemia pirinixic acid 3.2120558911
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 1.9118670907 18850075
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 4.1315338365
MESH:D007021 Hypospadias Ethinyl Estradiol 3.8516569931 16945680
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.4912013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 2.5017937319
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 1.8712878042 12200463
MESH:D007333 Insulin Resistance Estradiol 7.2616627594 16393666
MESH:D007333 Insulin Resistance pirinixic acid 7.2616306350
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 3.3616580747
MESH:D007674 Kidney Diseases Acetaminophen 5.9415629191 12587719
MESH:D007674 Kidney Diseases Estradiol 5.9415618244
MESH:D007680 Kidney Neoplasms 2,4-dinitrotoluene 17.9716705839
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 17.9716705839
MESH:D007680 Kidney Neoplasms Estradiol 17.9715610895
MESH:D007680 Kidney Neoplasms Fluorouracil 17.9716985049
MESH:D007938 Leukemia arsenic trioxide 2.8415070760
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 3.8212560223 17077332
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 4.3616972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 3.4514633726
MESH:D007951 Leukemia, Myeloid arsenic trioxide 3.7919077051
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 2.1417050201 16467208 16968895 19850784 20471514
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 3.2312679006 11468182 19075265 12018890 17649720 17217047 19642359 17869043 12712474 15622746 15213294 16331271 9834237 16330433 17712046 17107899 16891316 19225113 19035177 11161223 16823087 15336539 15748426 16966277 16112521
MESH:D015458 Leukemia, T-Cell arsenic trioxide 4.3916882451
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 2.8211408273 16943688 21278145 16239168 17174718 11903743 17334410 16221502 17157831
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 4.9413678700 15959796 17525996 18277467 12898905 16136751 17557913 18263696 18418968 17714472 12445421 17708605 18210741 18251166 17805973 16015684 12546737 15925388 15673190 12445418 12632514 17823541 18156304 17761835 17640975 18376398 15876570 18472094 18412020 17922224 12667390 14716496 16248980 15818738 15730626 16097048 12958196 16033810 15338365 14748882 15362042 18054572 18395095 17869086 15123356 12389079 17766677 15370692 18166357 17900296 18481824 14620537 12609069 18006644 18205269 15931870 14716833 18472332 16027843 17698563 17565644 14512876 18317297 16638106 17944888 15052691 15057751 17481882 18705752 12666154 16116963 18395914 18420326 12649538 18279442 15996030 16011737 17631135 16192424 12632512 17721639 17976157 10355542 14724832 12741479 12586293 15893842 15650968 11481614 18429990 20821823 18187930 18339082
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 4.9414716833 14659978
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 4.9415474484
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 4.9412878042
MESH:D008107 Liver Diseases Acetaminophen 3.9219784758 12587719 19460945 16611625 16610002 12969438 11587558 19014921
MESH:D008107 Liver Diseases Carbon Tetrachloride 3.9217285989 16964402 15830285 16246199 15720792
MESH:D017093 Liver Failure Carbon Tetrachloride 4.2115123358
MESH:D017114 Liver Failure, Acute Acetaminophen 9.5016871587 17185352
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 9.5014706259 16899240
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 22.097678174
MESH:D008113 Liver Neoplasms arsenic trioxide 22.0914682389
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 22.0921137059 20195826
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 22.0919294768
MESH:D008113 Liver Neoplasms Fluorouracil 22.0916603448 17045692 15113037 18383874
MESH:D008113 Liver Neoplasms pirinixic acid 22.0916377806 15890375 20007298
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 22.0916984957
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 14.256135515 2876786 2876784
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 14.2520377131
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 14.2512014681 15583823
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 14.2512151625
MESH:D008133 Long QT Syndrome arsenic trioxide 3.3715213294
MESH:D008175 Lung Neoplasms arsenic trioxide 4.8619825857 11798837
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 4.866695378 20464547 20135361 18569708 18816296 20064080 18520028 17053015 20869020
MESH:D008175 Lung Neoplasms Fluorouracil 4.8615246190
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 4.8611884234 19555203
MESH:D008178 Lupus Erythematosus, Cutaneous Fluorouracil 4.8415086387
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 2.5817203775 11807958 11408345 16891317
MESH:D020149 Manganese Poisoning Estradiol 4.5519453300
MESH:D008546 Melanoma, Experimental Acetaminophen 3.6119513568
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 8.6016381670
MESH:D009062 Mouth Neoplasms Fluorouracil 8.6016757204 18986760
MESH:D052016 Mucositis irinotecan 5.0617159606
MESH:D009101 Multiple Myeloma arsenic trioxide 3.1219417148 14977855 15949261 11468182 19549372
MESH:D009135 Muscular Diseases pirinixic acid 3.5516239165
MESH:D009182 Mycosis Fungoides arsenic trioxide 4.7318349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 3.1616882451 16105982
MESH:D009203 Myocardial Infarction pirinixic acid 2.1519151258
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 3.0412213967
MESH:D015428 Myocardial Reperfusion Injury Estradiol 8.3216810080
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 8.3216411023
MESH:D009336 Necrosis 2,4-dinitrotoluene 10.5218551238
MESH:D009336 Necrosis 2,6-dinitrotoluene 10.527678174 18551238
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 4.0016624393
MESH:D009362 Neoplasm Metastasis irinotecan 3.1818259882
MESH:D009369 Neoplasms Benzo(a)pyrene 8.3011141357
MESH:D009369 Neoplasms Fluorouracil 8.3018239605 18600527 16928823
MESH:D009369 Neoplasms pirinixic acid 8.3017405874
MESH:D009389 Neovascularization, Pathologic Estradiol 3.7817289903
MESH:D009421 Nervous System Malformations Estradiol 9.5911399458 16427766
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 9.5914600291
MESH:D009436 Neural Tube Defects arsenic trioxide 3.1310525206
MESH:D009447 Neuroblastoma irinotecan 3.498761367
MESH:D019636 Neurodegenerative Diseases Acetaminophen 2.8918514411
MESH:D017599 Neuroectodermal Tumors irinotecan 4.788761367
MESH:D020258 Neurotoxicity Syndromes Fluorouracil 3.4516436463
MESH:D009765 Obesity pirinixic acid 1.8220558911
MESH:D009784 Occupational Diseases 2,4-dinitrotoluene 8.9816049721 12819281
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 8.9816049721
MESH:D010051 Ovarian Neoplasms arsenic trioxide 4.8519769630 16624393 12452020
MESH:D010051 Ovarian Neoplasms Estradiol 4.8519401270
MESH:D010146 Pain Acetaminophen 2.4116870215
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 5.3915580305
MESH:D010190 Pancreatic Neoplasms Fluorouracil 5.3916500647 19003803 15113037 16929163
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.7211578682
MESH:D010235 Paraganglioma arsenic trioxide 4.1919927285
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.3112520081
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.5918163543
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 3.2411222880 11118676 11399792 11896295
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 3.9120887781
MESH:D011471 Prostatic Neoplasms arsenic trioxide 2.0619131511
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 2.0617292933
MESH:D011471 Prostatic Neoplasms Estradiol 2.0616740699
MESH:D011471 Prostatic Neoplasms Fluorouracil 2.0618626508 19082440
MESH:D011537 Pruritus Ethinyl Estradiol 3.3615861022 16919318
MESH:D012004 Rectal Neoplasms Fluorouracil 4.0418286688 15538739 16160472 18722050
MESH:D015427 Reperfusion Injury pirinixic acid 2.4019058328
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.8718990726
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 4.0016646077
MESH:D012640 Seizures 2,4-dinitrotoluene 5.9318551238
MESH:D012640 Seizures 2,6-dinitrotoluene 5.9318551238
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 5.5119755658 10029692
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 5.5116192470
MESH:D013088 Spermatocele Ethinyl Estradiol 4.0016709447
MESH:D013274 Stomach Neoplasms arsenic trioxide 4.7717007042
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 4.7720155912 2093021
MESH:D013274 Stomach Neoplasms Fluorouracil 4.7717172411 17522103 19015929 17498489 19084572 16424979 16951190 18567086 15786421 18396642
MESH:D013274 Stomach Neoplasms irinotecan 4.7715723263
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.6511994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.1815669648
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.9612697716
MESH:D013964 Thyroid Neoplasms arsenic trioxide 3.1119014326
MESH:D013978 Tibial Fractures Estradiol 4.7519048282
MESH:D014062 Tongue Neoplasms Fluorouracil 4.0216280240
MESH:D016171 Torsades de Pointes arsenic trioxide 4.0115213294
MESH:D001749 Urinary Bladder Neoplasms 2,4-dinitrotoluene 12.0016049721
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 12.0016049721
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 12.0011780464 20435036 12973940 12845720
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 12.0017053015
MESH:D014571 Urologic Neoplasms 2,4-dinitrotoluene 12.1610091137
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 12.1610091137
MESH:D014581 Urticaria Acetaminophen 3.0110982225
MESH:D002583 Uterine Cervical Neoplasms Fluorouracil 3.9016803524
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 3.3314692618
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.6612125929
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.5715869587 14671159
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.3115886252
No data
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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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