AutismKB 2.0

Annotation Detail for TNFRSF12A


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Basic Information Top
Gene Symbol:TNFRSF12A ( CD266,FN14,TWEAKR )
Gene Full Name: tumor necrosis factor receptor superfamily, member 12A
Band: 16p13.3
Quick LinksEntrez ID:51330; OMIM: 605914; Uniprot ID:TNR12_HUMAN; ENSEMBL ID: ENSG00000006327; HGNC ID: 18152
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa04060Cytokine-cytokine receptor interaction
No data
No data
No data
No data
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C548651 2-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester 2-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester results in decreased expression of TNFRSF12A mRNAdecreases expression 19933214
C016403 2,4-dinitrotoluene 2,4-dinitrotoluene affects the expression of TNFRSF12A mRNAaffects expression 21346803
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene affects the expression of TNFRSF12A mRNAaffects expression 21346803
C026137 3-hydroxyacetanilide 3-hydroxyacetanilide results in increased expression of TNFRSF12A mRNAincreases expression 18544908
C009505 4,4'-diaminodiphenylmethane 4,4'-diaminodiphenylmethane results in decreased expression of TNFRSF12A mRNAdecreases expression 18648102
D000082 Acetaminophen Acetaminophen affects the expression of TNFRSF12A mRNAaffects expression 17562736
D000082 Acetaminophen Acetaminophen results in increased expression of TNFRSF12A mRNAincreases expression 18544908
D000082 Acetaminophen Acetaminophen results in increased expression of TNFRSF12A mRNAincreases expression 17202762
D000643 Ammonium Chloride Ammonium Chloride affects the expression of TNFRSF12A mRNAaffects expression 16483693
D016718 Arachidonic Acid Arachidonic Acid results in increased expression of TNFRSF12A mRNAincreases expression 16704987
C006632 arsenic trioxide arsenic trioxide results in decreased expression of TNFRSF12A mRNAdecreases expression 19128835
C015001 arsenite arsenite results in increased expression of TNFRSF12A mRNAincreases expression 18585952
C015001 arsenite XPA protein affects the reaction [arsenite results in increased expression of TNFRSF12A mRNA]affects reaction|increases expression 18585952
C015001 arsenite arsenite results in increased expression of TNFRSF12A mRNAincreases expression 18191166
D017638 Asbestos, Crocidolite Asbestos, Crocidolite results in increased expression of TNFRSF12A mRNAincreases expression 18687144
D019324 beta-Naphthoflavone beta-Naphthoflavone results in increased expression of TNFRSF12A mRNAincreases expression 19737606
D019324 beta-Naphthoflavone [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of TNFRSF12A mRNAaffects cotreatment|increases expression 18164116
C459604 candoxin candoxin results in increased expression of TNFRSF12A mRNAincreases expression 16309724
D002251 Carbon Tetrachloride Carbon Tetrachloride results in increased expression of TNFRSF12A mRNAincreases expression 18038451
D002251 Carbon Tetrachloride Carbon Tetrachloride results in increased expression of TNFRSF12A proteinincreases expression 18038451
D002251 Carbon Tetrachloride PPARD protein affects the reaction [Carbon Tetrachloride results in increased expression of TNFRSF12A mRNA]affects reaction|increases expression 18038451
D002251 Carbon Tetrachloride PPARD protein affects the reaction [Carbon Tetrachloride results in increased expression of TNFRSF12A protein]affects reaction|increases expression 18038451
D002995 Clofibric Acid Clofibric Acid affects the expression of TNFRSF12A mRNAaffects expression 17602206
C057862 cyanoginosin LR cyanoginosin LR results in increased expression of TNFRSF12A mRNAincreases expression 17654400
D016572 Cyclosporine Cyclosporine results in increased expression of TNFRSF12A mRNAincreases expression 20106945
D004052 Diethylnitrosamine [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of TNFRSF12A mRNAaffects cotreatment|increases expression 18164116
D004052 Diethylnitrosamine Diethylnitrosamine results in increased expression of TNFRSF12A mRNAincreases expression 19638242
D004958 Estradiol Estradiol inhibits the reaction [Etoposide results in increased expression of TNFRSF12A mRNA]decreases reaction|increases expression 19426747
D004958 Estradiol Estradiol results in decreased expression of TNFRSF12A mRNAdecreases expression 19426747
D004958 Estradiol Estradiol results in increased expression of TNFRSF12A mRNAincreases expression 20106945
D005047 Etoposide Estradiol inhibits the reaction [Etoposide results in increased expression of TNFRSF12A mRNA]decreases reaction|increases expression 19426747
D005047 Etoposide Etoposide results in increased expression of TNFRSF12A mRNAincreases expression 19426747
D005492 Folic Acid Folic Acid results in increased expression of TNFRSF12A mRNAincreases expression 17003819
D005492 Folic Acid Folic Acid results in increased expression of TNFRSF12A proteinincreases expression 17003819
D019833 Genistein Genistein results in decreased expression of TNFRSF12A mRNAdecreases expression 16705744
D008466 Mechlorethamine Mechlorethamine results in decreased expression of TNFRSF12A mRNAdecreases expression 17107856
C030957 methylmercury II methylmercury II results in increased expression of TNFRSF12A mRNAincreases expression 17905399
D008770 Methylnitrosourea Methylnitrosourea results in increased expression of TNFRSF12A mRNAincreases expression 17412507
C029938 nickel sulfate nickel sulfate results in increased expression of TNFRSF12A mRNAincreases expression 16100012
C014707 nitrosobenzylmethylamine nitrosobenzylmethylamine results in increased expression of TNFRSF12A mRNAincreases expression 17616710
D010126 Ozone Ozone results in increased expression of TNFRSF12A mRNAincreases expression 17095637
19555225
D010656 Phenylephrine Phenylephrine results in increased expression of TNFRSF12A mRNAincreases expression 18158353
D012643 Selenium Selenium results in increased expression of TNFRSF12A mRNAincreases expression 19244175
C017947 sodium arsenite sodium arsenite results in increased expression of TNFRSF12A mRNAincreases expression 16014739
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of TNFRSF12A mRNAincreases expression 20106945
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of TNFRSF12A mRNAdecreases expression 19465110
19933214
D014212 Tretinoin [Tretinoin co-treated with zoledronic acid] results in increased expression of TNFRSF12A mRNAaffects cotreatment|increases expression 20349282
C034613 triacsin C triacsin C results in increased expression of TNFRSF12A mRNAincreases expression 16704987
D014241 Trichloroethylene Trichloroethylene results in increased expression of TNFRSF12A mRNAincreases expression 17905399
D001335 Vehicle Emissions Vehicle Emissions results in increased expression of TNFRSF12A mRNAincreases expression 19465080
C088658 zoledronic acid [Tretinoin co-treated with zoledronic acid] results in increased expression of TNFRSF12A mRNAaffects cotreatment|increases expression 20349282
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 2.4714514962 11752688 15322242
MESH:D000138 Acidosis Ammonium Chloride 3.1818287403
MESH:D058186 Acute Kidney Injury Folic Acid 8.1216316344 17003819 16595132
MESH:D058186 Acute Kidney Injury zoledronic acid 8.1219715164
MESH:D055371 Acute Lung Injury nickel sulfate 3.9612718980 11954676 16100012 19131640
MESH:D000210 Acute-Phase Reaction zoledronic acid 5.1020200999
MESH:D000230 Adenocarcinoma arsenic trioxide 9.3319825857 11798837
MESH:D000230 Adenocarcinoma Estradiol 9.3311473722
MESH:D000230 Adenocarcinoma Genistein 9.3311473722
MESH:D000230 Adenocarcinoma Methylnitrosourea 9.3315688392 15113128
MESH:D000236 Adenoma 4,4'-diaminodiphenylmethane 14.183712494
MESH:D000236 Adenoma beta-Naphthoflavone 14.1819389873
MESH:D000236 Adenoma Diethylnitrosamine 14.1810737359 6695378
MESH:D000236 Adenoma Folic Acid 14.1816963246
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 8.7918056438 19061943 19052882 16434500 17162532 17620307
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 8.7916835633
MESH:D000310 Adrenal Gland Neoplasms sodium arsenite 4.3115276417
MESH:D018246 Adrenocortical Adenoma sodium arsenite 4.5117306315 16712894
MESH:D000505 Alopecia Tretinoin 3.3215955085
MESH:D000544 Alzheimer Disease Folic Acid 4.2317116317
MESH:D000544 Alzheimer Disease Ozone 4.2315513908
MESH:D000740 Anemia Tetrachlorodibenzodioxin 2.6211748828
MESH:D000799 Angioedema Acetaminophen 3.4610982225
MESH:D001145 Arrhythmias, Cardiac Phenylephrine 3.7817460149
MESH:D001169 Arthritis, Experimental Tretinoin 2.8416412693
MESH:D001172 Arthritis, Rheumatoid Ozone 4.3315570426
MESH:D001172 Arthritis, Rheumatoid Tretinoin 4.3316292516
MESH:D001249 Asthma Ozone 4.5317854713 16373670
MESH:D001249 Asthma Tretinoin 4.5316456186
MESH:D001321 Autistic Disorder Acetaminophen 2.2818445737
MESH:D001321 Autistic Disorder Arachidonic Acid 2.2818582451
MESH:D001321 Autistic Disorder Folic Acid 2.2821388746
MESH:D001471 Barrett Esophagus Tretinoin 4.0416935849
MESH:D001660 Biliary Tract Diseases 4,4'-diaminodiphenylmethane 4.631440618 11289319
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 13.3716206674
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 13.3712125929
MESH:D001778 Blood Coagulation Disorders Tretinoin 13.3716206674 16197459
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.4015340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.5215746008
MESH:D019046 Bone Marrow Neoplasms Etoposide 4.7714601052
MESH:D001859 Bone Neoplasms zoledronic acid 4.6116121404 16778634 19442620 17312309 11697798 15867366
MESH:D001862 Bone Resorption zoledronic acid 4.3611869084 8053405 16769263 18496637 15845617 18404659
MESH:D001919 Bradycardia Phenylephrine 4.1615306635
MESH:D001943 Breast Neoplasms Diethylnitrosamine 6.5317474063
MESH:D001943 Breast Neoplasms Estradiol 6.5318497071 12948864 19861407 17289903 17261762 16675129 17018787 14630087
MESH:D001943 Breast Neoplasms Etoposide 6.5316322251
MESH:D001943 Breast Neoplasms Folic Acid 6.5316777985
MESH:D001943 Breast Neoplasms Genistein 6.5316873071 16541309 17200150
MESH:D001943 Breast Neoplasms Methylnitrosourea 6.5311306469 14633655 16253758
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 6.5320435547
MESH:D001943 Breast Neoplasms Tretinoin 6.5316873071 16443354 16166294
MESH:D001943 Breast Neoplasms Trichloroethylene 6.5315986119
MESH:D001943 Breast Neoplasms zoledronic acid 6.5316096432 18695136
MESH:D016535 Bronchial Hyperreactivity Ozone 3.3816777450 18315731 19059883 15516495 14754758 17626835 18417511
MESH:D001997 Bronchopulmonary Dysplasia Tretinoin 4.2116813970
MESH:D002051 Burkitt Lymphoma arsenic trioxide 3.9811589617
MESH:D002057 Burns, Chemical Mechlorethamine 5.849625245
MESH:D002100 Cachexia Ozone 4.3616183385
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 4.0816111702
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 3.4116227642 10355542 16050911 16124888 15721981 16097048 16192424 3786805 15700767 18705752 15673190 16011737
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.5016835633
MESH:D018236 Carcinoma, Embryonal Tretinoin 4.7716168501
MESH:D006528 Carcinoma, Hepatocellular 2,4-dinitrotoluene 24.4516705839
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 24.4516705839
MESH:D006528 Carcinoma, Hepatocellular 4,4'-diaminodiphenylmethane 24.453581430 7296757
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 24.453084413
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 24.4514691202 15073043 16217749 11135700 15553829
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 24.4518788625
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 24.4520432363 3084413 10737359 19394651 20101231 18506893 19383236 19335982 18056438 16779866 19418558 17761372 16569478 11831363 16681979 18788625 16935385 19539802 18978308 17138121 17055752 20084675 19107877 19208518 16540662 19701751 18971187 20524982 19919837 17173139 18494052 19519916 16698587 20514400 17162532 17428255 16830150 20727157 10672840 3581430 18691550 20007298 18665156 18785209 20214788 19822196 20512989 17978847 19052882 18210153 18393292 20935162 16288022 21159647 16328049 16502159 16807293 16878318 19171122
MESH:D006528 Carcinoma, Hepatocellular Estradiol 24.4516924424
MESH:D006528 Carcinoma, Hepatocellular Genistein 24.4516924424
MESH:D006528 Carcinoma, Hepatocellular sodium arsenite 24.4515276417 16507464 17306315
MESH:D006528 Carcinoma, Hepatocellular Tretinoin 24.451917145
MESH:D002289 Carcinoma, Non-Small-Cell Lung zoledronic acid 3.4019233551
MESH:D002291 Carcinoma, Papillary arsenic trioxide 4.4919014326
MESH:D002292 Carcinoma, Renal Cell 4,4'-diaminodiphenylmethane 6.187296757
MESH:D002292 Carcinoma, Renal Cell zoledronic acid 6.1818507039
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 3.7912490120
MESH:D002294 Carcinoma, Squamous Cell sodium arsenite 4.2818572023
MESH:D002294 Carcinoma, Squamous Cell Tretinoin 4.2816051514 16096774
MESH:D006332 Cardiomegaly Phenylephrine 6.1611754973 17124262 11179087 16170337 17287366 15728586
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 6.1618850075 18670907 16120746
MESH:D002318 Cardiovascular Diseases Folic Acid 6.8116755160
MESH:D002318 Cardiovascular Diseases Genistein 6.8116332659
MESH:D002386 Cataract Acetaminophen 11.1010977129
MESH:D002386 Cataract Methylnitrosourea 11.1012484553
MESH:D002386 Cataract Tretinoin 11.1017460283
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 27.766135515
MESH:D002471 Cell Transformation, Neoplastic 4,4'-diaminodiphenylmethane 27.767505956
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 27.7612371664
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 27.7621159647 17174075 7505956 2727394
MESH:D002471 Cell Transformation, Neoplastic Estradiol 27.7618566989
MESH:D002471 Cell Transformation, Neoplastic Methylnitrosourea 27.767505956 2727394
MESH:D002471 Cell Transformation, Neoplastic sodium arsenite 27.7619524636 20056578
MESH:D018290 Cervical Intraepithelial Neoplasia Tretinoin 4.2116129372
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 8.2619052882
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 8.2616835633
MESH:D002779 Cholestasis 4,4'-diaminodiphenylmethane 6.949022650 19486331
MESH:D002779 Cholestasis Cyclosporine 6.9419486331
MESH:D002822 Choriocarcinoma Tretinoin 4.7716461808
MESH:D002971 Cleft Lip Folic Acid 3.7821254359
MESH:D002972 Cleft Palate Folic Acid 8.9221254359 8946559
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 8.9212621046 16354765 15668235 8697196 15340226
MESH:D002972 Cleft Palate Tretinoin 8.929407595
MESH:D003092 Colitis Selenium 8.2617936198
MESH:D003092 Colitis Tretinoin 8.2617035595
MESH:D003110 Colonic Neoplasms arsenite 3.7115037631
MESH:D003110 Colonic Neoplasms Genistein 3.7117182828
MESH:D015179 Colorectal Neoplasms arsenic trioxide 2.7020501625
MESH:D015179 Colorectal Neoplasms Folic Acid 2.7016963246 17116713 17087956 17245555 16985020
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 2.7414669216 17141729
MESH:D023903 Coronary Restenosis arsenic trioxide 3.8212609071
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 3.4910525206
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 3.4910048152 15322242 20055451
MESH:D019465 Craniofacial Abnormalities Tretinoin 3.4914991402 10589399 8800419 17551590 9224671 9211117 9664655 9142499 9125849 16925845
MESH:D003490 Cyanosis 2,4-dinitrotoluene 9.6518551238
MESH:D003490 Cyanosis 2,6-dinitrotoluene 9.6518551238
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 3.7415213294
MESH:D017449 Dermatitis, Allergic Contact 4,4'-diaminodiphenylmethane 5.9318759878 8156756 11906362 8970840 11298694 12868966 2524372 14531868
MESH:D017449 Dermatitis, Allergic Contact nickel sulfate 5.9316823706 16780908 11298694
MESH:D003877 Dermatitis, Contact 4,4'-diaminodiphenylmethane 3.142952479 3621924
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 9.3920387270
MESH:D003924 Diabetes Mellitus, Type 2 Folic Acid 9.3916886840
MESH:D003924 Diabetes Mellitus, Type 2 Genistein 9.3916647724
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 9.3917107852
MESH:D003928 Diabetic Nephropathies Estradiol 3.0919279558
MESH:D056486 Drug-Induced Liver Injury 2,4-dinitrotoluene 26.9818551238 21346803
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 26.9818551238 21346803
MESH:D056486 Drug-Induced Liver Injury 4,4'-diaminodiphenylmethane 26.9818692083 7440962 8291058 16192314 6482804 6679447 18648102 9328219 11289319 1440618 9653073 9022650 18289764
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 26.9816177239 11743745 12705907 12392966 17906064 19923254 18071297 10663392 10915739 16393943 18713872 16227642 11461765 17562736 16781746 15619225 12153990 14986274 11287661 19370779 19739265 19420014 19416960 16081117 14725611 11421492 14550746 11834606 19085960 11739529 16109766 2444490 10774834 17522070 19164858 12958197 12594235 16485898 12540782 11529661 15968718
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 26.987440962 21278145 19085960 7120509 6623471 2869522 16227642 10092053 16177239 6884620 15968718 10915739 15998439 3732212 11566570 3786805 17522070 15027814 4309450 19336974 9327722 7179309
MESH:D056486 Drug-Induced Liver Injury cyanoginosin LR 26.9817654400
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 26.9819107877
MESH:D056486 Drug-Induced Liver Injury Selenium 26.9815131321
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 26.9820420201
MESH:D056486 Drug-Induced Liver Injury Trichloroethylene 26.987120509
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 3.7119426721
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.4811462148
MESH:D004487 Edema Arachidonic Acid 6.0111698051 9599246 16716910 7990266 9831321 15177302
MESH:D004487 Edema Tetrachlorodibenzodioxin 6.0112711302 11000095
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 10.6516714409 18230668 15322242
MESH:D004489 Edema, Cardiac Tretinoin 10.6518230668
MESH:D004714 Endometrial Hyperplasia Genistein 4.2116402032
MESH:D016889 Endometrial Neoplasms Estradiol 15.7618566989 19148513 11473722
MESH:D016889 Endometrial Neoplasms Folic Acid 15.7617301261
MESH:D016889 Endometrial Neoplasms Genistein 15.7611473722
MESH:D016889 Endometrial Neoplasms Tretinoin 15.7616569247
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 2.6910568697 9294722
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 4.7316302075
MESH:D004938 Esophageal Neoplasms 4,4'-diaminodiphenylmethane 6.673581430
MESH:D004938 Esophageal Neoplasms arsenic trioxide 6.6712903497
MESH:D004938 Esophageal Neoplasms nitrosobenzylmethylamine 6.6716704527 15150132 15547721 15878914 15623463 15547733 16805852 16510608 15264214
MESH:D017889 Exfoliation Syndrome Folic Acid 5.1116504073
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 7.9011564622
MESH:D005124 Eye Abnormalities Tretinoin 7.9016938888 9664655
MESH:D005234 Fatty Liver arsenic trioxide 21.0615073043
MESH:D005234 Fatty Liver arsenite 21.0618296743
MESH:D005234 Fatty Liver Carbon Tetrachloride 21.0615959796 12795759 16045604 16239168 12631006 17595544 61145 19224547
MESH:D005234 Fatty Liver Cyclosporine 21.0619224547
MESH:D005234 Fatty Liver Diethylnitrosamine 21.0621071580 20387270
MESH:D005264 Femoral Fractures zoledronic acid 5.4516234978
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.0811858732
MESH:D005334 Fever Arachidonic Acid 4.3311852909
MESH:D005350 Fibroma 4,4'-diaminodiphenylmethane 4.636705139
MESH:D005354 Fibrosarcoma Methylnitrosourea 4.8511555667
MESH:D005355 Fibrosis arsenite 23.7818296743
MESH:D005355 Fibrosis Carbon Tetrachloride 23.7818705752
MESH:D005355 Fibrosis Cyclosporine 23.7812168785 12639820
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 23.7820067830
MESH:D005355 Fibrosis Tretinoin 23.7817994277
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 3.9016904648
MESH:D005756 Gastritis Acetaminophen 9.9816983495
MESH:D005756 Gastritis Folic Acid 9.9817171786
MESH:D005833 Genital Neoplasms, Female sodium arsenite 4.3016452187
MESH:D005885 Gingival Hyperplasia Cyclosporine 3.848708960
MESH:D005901 Glaucoma Folic Acid 4.7316504073
MESH:D005909 Glioblastoma Genistein 6.3816598420
MESH:D005909 Glioblastoma Tretinoin 6.3817312396
MESH:D005910 Glioma Methylnitrosourea 3.419825942
MESH:D006042 Goiter 4,4'-diaminodiphenylmethane 3.697505956
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.2110696789
MESH:D006258 Head and Neck Neoplasms Tretinoin 2.9316096774
MESH:D006317 Hearing Loss, Noise-Induced Tretinoin 4.7716084493
MESH:D006330 Heart Defects, Congenital Folic Acid 10.0416524890 17286298
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 10.0410048152 11294989
MESH:D006330 Heart Defects, Congenital Tretinoin 10.049664655 14991402
MESH:D006333 Heart Failure Selenium 2.8417162251
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.0415720958
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.0011000095
MESH:D006505 Hepatitis 4,4'-diaminodiphenylmethane 8.026705139
MESH:D006505 Hepatitis Carbon Tetrachloride 8.0219900420 19110552
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 2.5312621046 16120746 15340226
MESH:D006558 Herpes Genitalis Estradiol 4.6415709030
MESH:D006561 Herpes Simplex Etoposide 4.1810809021
MESH:D006679 HIV Seropositivity Folic Acid 5.1117209195
MESH:D006689 Hodgkin Disease Etoposide 6.6015147373 18180244 17606976 16200630 16135485
MESH:D006689 Hodgkin Disease sodium arsenite 6.6012676792
MESH:D019584 Hot Flashes Estradiol 3.3717088409
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.6615340226 18606429 16354765 16959395 8697196
MESH:D006930 Hyperalgesia Acetaminophen 11.4116870215
MESH:D006930 Hyperalgesia Tretinoin 11.4116870215
MESH:D006930 Hyperalgesia zoledronic acid 11.4116769263
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 4.1516899240
MESH:D006934 Hypercalcemia zoledronic acid 4.7118089816 19622757
MESH:D017681 Hypereosinophilic Syndrome Tretinoin 4.2016778211
MESH:D020138 Hyperhomocysteinemia Folic Acid 4.1816865747 16755160 16397167 16395265 16433478
MESH:D006965 Hyperplasia 4,4'-diaminodiphenylmethane 3.5715034207
MESH:D006973 Hypertension Cyclosporine 7.7010903974
MESH:D006973 Hypertension Phenylephrine 7.7012717712 8949925
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 7.7018670907 18850075
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 3.7215338365
MESH:D006984 Hypertrophy Phenylephrine 4.2118502941 12791704
MESH:D006996 Hypocalcemia zoledronic acid 5.8012669777
MESH:D007248 Infertility, Male Methylnitrosourea 6.277193160
MESH:D007248 Infertility, Male sodium arsenite 6.2712646999 15346721
MESH:D007249 Inflammation Arachidonic Acid 7.249831321 15177302 17371808
MESH:D007249 Inflammation Diethylnitrosamine 7.2418785209
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 7.2412878042 12200463
MESH:D007251 Influenza, Human Selenium 3.8116624496
MESH:D007333 Insulin Resistance Estradiol 2.7216393666 16627594
MESH:D007410 Intestinal Diseases Tretinoin 3.4017994277
MESH:D007565 Jaundice 4,4'-diaminodiphenylmethane 4.639022650 8074119
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 8.8016580747
MESH:D007569 Jaw Abnormalities Tretinoin 8.8017551590 15992940
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.0515604871
MESH:D007674 Kidney Diseases Acetaminophen 12.5612587719 15629191
MESH:D007674 Kidney Diseases Cyclosporine 12.5618776723 8314463 10903974
MESH:D007674 Kidney Diseases Estradiol 12.5615618244
MESH:D007674 Kidney Diseases sodium arsenite 12.5620008137
MESH:D007676 Kidney Failure, Chronic Selenium 3.5516518626
MESH:D007680 Kidney Neoplasms 2,4-dinitrotoluene 20.0616705839
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 20.0616705839
MESH:D007680 Kidney Neoplasms 4,4'-diaminodiphenylmethane 20.066582329
MESH:D007680 Kidney Neoplasms Cyclosporine 20.0612371664
MESH:D007680 Kidney Neoplasms Estradiol 20.0615610895
MESH:D007938 Leukemia arsenic trioxide 9.3515070760
MESH:D007938 Leukemia Genistein 9.3518980019 17468513
MESH:D007938 Leukemia Tretinoin 9.3517143497
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 8.8417077332 12560223
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell zoledronic acid 8.8418089816
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 3.9316972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 3.1514633726
MESH:D007951 Leukemia, Myeloid arsenic trioxide 8.3419077051
MESH:D007951 Leukemia, Myeloid Tretinoin 8.3416932348 19285840 16482212
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 3.6220471514 17050201 19850784 16467208 16968895
MESH:D015470 Leukemia, Myeloid, Acute Tretinoin 3.6217596541 19850784 16294345
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 6.8016823087 17869043 17649720 16330433 16891316 11468182 15622746 12018890 15213294 17217047 19075265 11161223 17107899 16331271 17712046 19225113 16112521 15748426 9834237 15336539 19642359 16966277 12712474 19035177 12679006
MESH:D015473 Leukemia, Promyelocytic, Acute Tretinoin 6.8016891316 19029980 17301526 17712046 17649720 16766008 16935935 17339181 16823087 17217047 17361223 19642359 19075265 17368321 17294898 12679006 16788101 17107899 19035177 17506722 9834237 15748426 16140955 16331271 19225113
MESH:D015458 Leukemia, T-Cell arsenic trioxide 3.9916882451
MESH:D017880 Limb Deformities, Congenital Methylnitrosourea 7.5515526292
MESH:D017880 Limb Deformities, Congenital Tretinoin 7.559224671
MESH:D008103 Liver Cirrhosis arsenite 9.8418296743
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 9.8417334410 17174718 21278145 11903743 11408273 16221502 17157831 16943688 16239168
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 9.8420032147 19638242 18522880 18665156 18407596
MESH:D008105 Liver Cirrhosis, Biliary 4,4'-diaminodiphenylmethane 2.9615034207 9327722
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 6.1412667390 18395095 15123356 18395914 15338365 17557913 15730626 16015684 17525996 14512876 18339082 15370692 12445421 12666154 12741479 17823541 18187930 14724832 18279442 15931870 13678700 15959796 15673190 14716833 12958196 12546737 17805973 18263696 16248980 17565644 17640975 15057751 12632514 17944888 18156304 18277467 15876570 15052691 17766677 12609069 18429990 14716496 18210741 16097048 12586293 18006644 12632512 15650968 16027843 15893842 18205269 17869086 15996030 17761835 17631135 18166357 18418968 14620537 17721639 15818738 15362042 16116963 16192424 18472094 10355542 17698563 17976157 20821823 18472332 17922224 18420326 12649538 18054572 15925388 17900296 16638106 18481824 17714472 11481614 18376398 18251166 18412020 18705752 16011737 16033810 16136751 12389079 12898905 17708605 17481882 12445418 14748882 18317297
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 6.1414716833 14659978
MESH:D008106 Liver Cirrhosis, Experimental Genistein 6.1417823541
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 6.1412878042
MESH:D008106 Liver Cirrhosis, Experimental Tretinoin 6.1416248980 18397230
MESH:D008107 Liver Diseases Acetaminophen 8.4819784758 12969438 11587558 16611625 16610002 19014921 12587719 19460945
MESH:D008107 Liver Diseases Carbon Tetrachloride 8.4817285989 16964402 15830285 16246199 15720792
MESH:D008107 Liver Diseases Diethylnitrosamine 8.4817034775
MESH:D008107 Liver Diseases Folic Acid 8.4816877991
MESH:D017093 Liver Failure Carbon Tetrachloride 3.7915123358
MESH:D017114 Liver Failure, Acute Acetaminophen 8.3116871587 17185352
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 8.3116899240 14706259
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 23.227678174
MESH:D008113 Liver Neoplasms arsenic trioxide 23.2214682389
MESH:D008113 Liver Neoplasms beta-Naphthoflavone 23.2219389873 21295105
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 23.2219294768
MESH:D008113 Liver Neoplasms Clofibric Acid 23.2217602206
MESH:D008113 Liver Neoplasms Diethylnitrosamine 23.2220118626 21047994 19090486 15175105 2422723 21278145 21167192 12771043 20583210 19254457 20501860 19812893 19996281 19638242 18978307 20137499 19255062 20101389 19642983 10737359 15885732 19426721 21071580 19690152 2862719 18648771 18977376 20492335 19850985 19833225 19551842 19294768 20434301 12112319 18754104 20405173 20452335 16942905 19499222 19073162 19256749 19427195 18644402 9163691
MESH:D008113 Liver Neoplasms sodium arsenite 23.2215276417 16712894
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 23.2216984957
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 29.062876784 2876786 6135515
MESH:D008114 Liver Neoplasms, Experimental 4,4'-diaminodiphenylmethane 29.06598648 6587162 1399818 3712494
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 29.0620377131
MESH:D008114 Liver Neoplasms, Experimental beta-Naphthoflavone 29.0618164116
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 29.0615583823 12014681
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 29.069362446 19539802 18308698 16267830 17174075 18544905 19004024 17942915 16842330 18164116 19519916 19126423 2563599 3124819 18282651 19009564 21159647 18079962 17854601 18253720 18775883 18093689
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 29.0612151625
MESH:D008114 Liver Neoplasms, Experimental Trichloroethylene 29.067955063
MESH:D008133 Long QT Syndrome arsenic trioxide 3.0615213294
MESH:D038061 Lower Extremity Deformities, Congenital Methylnitrosourea 5.0916080182
MESH:D008171 Lung Diseases Ozone 6.6619066396 8266340
MESH:D008171 Lung Diseases sodium arsenite 6.6619095001
MESH:D055370 Lung Injury Asbestos, Crocidolite 8.0117365036
MESH:D055370 Lung Injury Ozone 8.0120417186
MESH:D008175 Lung Neoplasms arsenic trioxide 12.0111798837 19825857
MESH:D008175 Lung Neoplasms arsenite 12.0116809336
MESH:D008175 Lung Neoplasms Diethylnitrosamine 12.0120512841 20970405 6695378 21163286
MESH:D008175 Lung Neoplasms Methylnitrosourea 12.0118062963
MESH:D008175 Lung Neoplasms Ozone 12.017614698 8597069
MESH:D008175 Lung Neoplasms sodium arsenite 12.0117306315 19931552 15276417 17077188 16712894
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 12.0111884234 19555203
MESH:D008175 Lung Neoplasms Vehicle Emissions 12.019255578
MESH:D008180 Lupus Erythematosus, Systemic Folic Acid 3.2217718048
MESH:D008223 Lymphoma Etoposide 7.2112854902 12556972
MESH:D008223 Lymphoma Methylnitrosourea 7.2116257854 11418001
MESH:D016393 Lymphoma, B-Cell Methylnitrosourea 4.4214633661
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 16.2316891317 17203775 11807958 11408345
MESH:D008325 Mammary Neoplasms, Experimental Genistein 16.2312929590 14578162
MESH:D008325 Mammary Neoplasms, Experimental Methylnitrosourea 16.2310838139 14999141 11807958 19196723 16827153 16944150 17131329 15688392 15313902 11751437 16619500 10767621 14633655 17020996 12931682 15113128 16051031
MESH:D008325 Mammary Neoplasms, Experimental Selenium 16.2315318939
MESH:D008325 Mammary Neoplasms, Experimental zoledronic acid 16.2317312309
MESH:D020149 Manganese Poisoning Estradiol 4.0919453300
MESH:D019767 Maxillofacial Abnormalities Folic Acid 5.3116832597
MESH:D008527 Medulloblastoma Tretinoin 2.6317453147
MESH:D008545 Melanoma sodium arsenite 3.1016487513 19082730
MESH:D008545 Melanoma Tretinoin 3.1016752155
MESH:D008546 Melanoma, Experimental Acetaminophen 3.2019513568
MESH:D008591 Meningomyelocele Tretinoin 4.0516940565
MESH:D008654 Mesothelioma Asbestos, Crocidolite 9.4116966607 16166281 18303189
MESH:D008654 Mesothelioma Selenium 9.4115107826
MESH:D008654 Mesothelioma zoledronic acid 9.4116675582
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.4016801185
MESH:D008679 Metaplasia Ozone 4.7210496685
MESH:D009101 Multiple Myeloma arsenic trioxide 6.7415949261 19549372 19417148 14977855 11468182
MESH:D009101 Multiple Myeloma zoledronic acid 6.7416996129 18089719 19621390
MESH:D009182 Mycosis Fungoides arsenic trioxide 4.2818349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 6.6516882451 16105982
MESH:D009190 Myelodysplastic Syndromes Tretinoin 6.6517596541
MESH:D009203 Myocardial Infarction Genistein 2.7017141266
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 2.7212213967
MESH:D015428 Myocardial Reperfusion Injury Estradiol 7.5516810080
MESH:D015428 Myocardial Reperfusion Injury Genistein 7.5517141266
MESH:D009336 Necrosis 2,4-dinitrotoluene 9.0818551238
MESH:D009336 Necrosis 2,6-dinitrotoluene 9.0818551238 7678174
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 3.6016624393
MESH:D009362 Neoplasm Metastasis 4,4'-diaminodiphenylmethane 8.663581430
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 8.669029167 3581430
MESH:D009362 Neoplasm Metastasis zoledronic acid 8.6615867366 19139120 17312309
MESH:D009369 Neoplasms Methylnitrosourea 10.3615533788
MESH:D009369 Neoplasms sodium arsenite 10.3611559025
MESH:D009369 Neoplasms Tretinoin 10.3616946489 16594593
MESH:D009369 Neoplasms Trichloroethylene 10.3611911487
MESH:D009374 Neoplasms, Experimental Methylnitrosourea 8.1712696579
MESH:D009374 Neoplasms, Experimental sodium arsenite 8.1720056578
MESH:D009389 Neovascularization, Pathologic arsenite 8.8815738583
MESH:D009389 Neovascularization, Pathologic Estradiol 8.8817289903
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.0517954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 2.9719348381 18481113
MESH:D009421 Nervous System Malformations Estradiol 20.4611399458 16427766
MESH:D009421 Nervous System Malformations Genistein 20.4616427766
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 20.4614600291
MESH:D009421 Nervous System Malformations Tretinoin 20.469125849
MESH:D009436 Neural Tube Defects 4,4'-diaminodiphenylmethane 20.116679447
MESH:D009436 Neural Tube Defects arsenic trioxide 20.1110525206
MESH:D009436 Neural Tube Defects Folic Acid 20.1117438019
MESH:D009436 Neural Tube Defects sodium arsenite 20.1112854658
MESH:D009436 Neural Tube Defects Tretinoin 20.119142499
MESH:D009442 Neurilemmoma Methylnitrosourea 5.1011555667
MESH:D019636 Neurodegenerative Diseases Acetaminophen 7.1618514411
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 7.1620387270
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 4.7320387270
MESH:D009503 Neutropenia Folic Acid 4.1616322990
MESH:D009784 Occupational Diseases 2,4-dinitrotoluene 13.1616049721 12819281
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 13.1616049721
MESH:D009784 Occupational Diseases 4,4'-diaminodiphenylmethane 13.164026338 6482804
MESH:D009902 Optic Neuritis 4,4'-diaminodiphenylmethane 4.633988306
MESH:D010014 Osteolysis zoledronic acid 4.9915867366
MESH:D010024 Osteoporosis Genistein 6.7819401787
MESH:D010024 Osteoporosis zoledronic acid 6.7817882678
MESH:D015663 Osteoporosis, Postmenopausal Genistein 3.7416169203
MESH:D010051 Ovarian Neoplasms arsenic trioxide 13.5719769630 12452020 16624393
MESH:D010051 Ovarian Neoplasms Estradiol 13.5719401270
MESH:D010051 Ovarian Neoplasms Genistein 13.5719005980
MESH:D010051 Ovarian Neoplasms sodium arsenite 13.5715276417 17306315
MESH:D010051 Ovarian Neoplasms Tretinoin 13.5716936753
MESH:D010146 Pain Acetaminophen 9.5716870215
MESH:D010146 Pain Tretinoin 9.5716870215
MESH:D010146 Pain zoledronic acid 9.5716475674
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 14.7715580305
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 14.7716540662
MESH:D010190 Pancreatic Neoplasms Etoposide 14.7719003803
MESH:D010190 Pancreatic Neoplasms Methylnitrosourea 14.7716965848
MESH:D010190 Pancreatic Neoplasms Tretinoin 14.7715976015
MESH:D010212 Papilloma 4,4'-diaminodiphenylmethane 3.117296757
MESH:D010235 Paraganglioma arsenic trioxide 3.8119927285
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 3.8612520081
MESH:D010538 Peritonitis Ozone 3.7616369182
MESH:D010787 Photosensitivity Disorders 4,4'-diaminodiphenylmethane 4.086228378
MESH:D010954 Plasmacytoma Selenium 4.5015087411
MESH:D010995 Pleural Diseases Asbestos, Crocidolite 4.5210923243
MESH:D011014 Pneumonia Ozone 4.0118381685 18007984 18929643
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.2018163543
MESH:D011230 Precancerous Conditions Cyclosporine 7.8812371664
MESH:D011230 Precancerous Conditions Diethylnitrosamine 7.882563599
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 2.8111222880 11896295 11399792 11118676
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 3.5420887781
MESH:D011471 Prostatic Neoplasms arsenic trioxide 2.0419131511
MESH:D011471 Prostatic Neoplasms Estradiol 2.0416740699
MESH:D011471 Prostatic Neoplasms Etoposide 2.0417172428
MESH:D011471 Prostatic Neoplasms Genistein 2.0415378649 16925846 15256057
MESH:D011471 Prostatic Neoplasms Methylnitrosourea 2.0415682402 12376480
MESH:D011471 Prostatic Neoplasms sodium arsenite 2.0416039940
MESH:D011471 Prostatic Neoplasms zoledronic acid 2.0419103299 12438248
MESH:D011507 Proteinuria Tretinoin 3.2616636307
MESH:D011565 Psoriasis Cyclosporine 2.0916882103
MESH:D011625 Pterygium Tretinoin 4.4116723453
MESH:D011658 Pulmonary Fibrosis Asbestos, Crocidolite 2.8817322281 17975199 15814490 17365031
MESH:D051437 Renal Insufficiency Folic Acid 4.4115728788
MESH:D012135 Respiratory Sounds Vehicle Emissions 4.8418950799
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.4718990726
MESH:D012162 Retinal Degeneration 4,4'-diaminodiphenylmethane 8.173692021
MESH:D012162 Retinal Degeneration Methylnitrosourea 8.1718172121 18155124
MESH:D012175 Retinoblastoma Methylnitrosourea 5.1011555667
MESH:D012208 Rhabdomyosarcoma Tretinoin 3.7516116481 16283617
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 15.3216646077
MESH:D012512 Sarcoma, Ewing's Etoposide 15.3214601052
MESH:D012512 Sarcoma, Ewing's zoledronic acid 15.3216121404
MESH:D012559 Schizophrenia Folic Acid 2.8416641680
MESH:D012640 Seizures 2,4-dinitrotoluene 5.0118551238
MESH:D012640 Seizures 2,6-dinitrotoluene 5.0118551238
MESH:D012852 Sinusitis Phenylephrine 4.327327846
MESH:D012871 Skin Diseases Folic Acid 3.1518709164
MESH:D012878 Skin Neoplasms sodium arsenite 8.3419524636 18572023
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 8.3416192470
MESH:D012878 Skin Neoplasms Tretinoin 8.3416467112
MESH:D013118 Spinal Cord Diseases Folic Acid 5.1116361298
MESH:D016135 Spinal Dysraphism sodium arsenite 3.5012854658
MESH:D013274 Stomach Neoplasms arsenic trioxide 7.7117007042
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 7.7118456281
MESH:D013274 Stomach Neoplasms Folic Acid 7.7117171786
MESH:D013274 Stomach Neoplasms Methylnitrosourea 7.7116257854 18593901 15930296
MESH:D013274 Stomach Neoplasms nitrosobenzylmethylamine 7.7117575124 12958204
MESH:D013274 Stomach Neoplasms Tretinoin 7.7117261132
MESH:D020521 Stroke Folic Acid 4.0316517955
MESH:D013953 Thymus Neoplasms Methylnitrosourea 4.8511418001
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.5112697716
MESH:D013964 Thyroid Neoplasms 4,4'-diaminodiphenylmethane 19.421399818 3712494 6587162 7505956 6582329
MESH:D013964 Thyroid Neoplasms arsenic trioxide 19.4219014326
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 19.427505956
MESH:D013964 Thyroid Neoplasms Methylnitrosourea 19.423078959 7505956
MESH:D013964 Thyroid Neoplasms Tretinoin 19.4217045167 16026305
MESH:D013978 Tibial Fractures Estradiol 4.3019048282
MESH:D014062 Tongue Neoplasms Tretinoin 3.4616051514
MESH:D016171 Torsades de Pointes arsenic trioxide 3.5815213294
MESH:D014376 Tuberculosis Tretinoin 2.9916040207
MESH:D001749 Urinary Bladder Neoplasms 2,4-dinitrotoluene 17.8116049721
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 17.8116049721
MESH:D001749 Urinary Bladder Neoplasms 4,4'-diaminodiphenylmethane 17.818074119
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 17.8111780464 12845720 12973940 20435036
MESH:D001749 Urinary Bladder Neoplasms sodium arsenite 17.8116452187 16712894 11723127 17306315
MESH:D001749 Urinary Bladder Neoplasms Vehicle Emissions 17.8111144890
MESH:D014571 Urologic Neoplasms 2,4-dinitrotoluene 10.7210091137
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 10.7210091137
MESH:D014581 Urticaria Acetaminophen 2.6310982225
MESH:D002583 Uterine Cervical Neoplasms sodium arsenite 8.3211813266
MESH:D002583 Uterine Cervical Neoplasms Tretinoin 8.3216129372
MESH:D014604 Uveal Neoplasms Tretinoin 4.2216752155
MESH:D014605 Uveitis Cyclosporine 3.601336536
MESH:D014652 Vascular Diseases sodium arsenite 4.0417056641
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.2112125929
MESH:D014820 Vitiligo Tretinoin 3.6916761959
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 3.8615886252
MESH:D009396 Wilms Tumor Tretinoin 3.6516287080
MESH:D014985 Xerophthalmia Cyclosporine 4.0517120751
Pathway ID Pathway Name
KEGG:04060 Cytokine-cytokine receptor interaction
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Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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