AutismKB 2.0

Annotation Detail for ZNF771


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Basic Information Top
Gene Symbol:ZNF771 ( DSC43 )
Gene Full Name: zinc finger protein 771
Band: 16p11.2
Quick LinksEntrez ID:51333; OMIM: NA; Uniprot ID:ZN771_HUMAN; ENSEMBL ID: ENSG00000179965; HGNC ID: 29653
Relate to Another Database: SFARIGene; denovo-db
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Chemical ID Chemical Name Interaction Interaction Action Publication
D000638 Amiodarone Amiodarone results in increased expression of ZNF771 mRNAincreases expression 19774075
D001151 Arsenic Arsenic affects the expression of ZNF771 mRNAaffects expression 18414638
C006632 arsenic trioxide arsenic trioxide results in decreased expression of ZNF771 mRNAdecreases expression 20458559
15761015
C025643 vinclozolin vinclozolin affects the expression of ZNF771 mRNAaffects expression 19015723
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000230 Adenocarcinoma arsenic trioxide 2.3611798837 19825857
MESH:D018246 Adrenocortical Adenoma Arsenic 5.9417306315
MESH:D001008 Anxiety Disorders vinclozolin 3.9719015723
MESH:D001145 Arrhythmias, Cardiac Amiodarone 4.2020041841 18218290 18057881
MESH:D020261 Arsenic Poisoning Arsenic 2.9516835338 12569548 16251483 18414634
MESH:D050197 Atherosclerosis Arsenic 3.4612928151 19371607
MESH:D001281 Atrial Fibrillation Amiodarone 4.2019698954 18651412
MESH:D001778 Blood Coagulation Disorders Amiodarone 10.7319483382
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 10.7316206674
MESH:D002051 Burkitt Lymphoma arsenic trioxide 4.7911589617
MESH:D002280 Carcinoma, Basal Cell Arsenic 3.7817687452 15504454
MESH:D006528 Carcinoma, Hepatocellular Arsenic 3.3716507464 17306315
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 3.3716217749 11135700 15553829 15073043 14691202
MESH:D002291 Carcinoma, Papillary arsenic trioxide 5.6019014326
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 4.5112490120
MESH:D002294 Carcinoma, Squamous Cell Arsenic 2.7715504454 17687452 18922899
MESH:D002295 Carcinoma, Transitional Cell Arsenic 4.4718640142
MESH:D002311 Cardiomyopathy, Dilated Amiodarone 3.0019225199 15710769
MESH:D002318 Cardiovascular Diseases Arsenic 3.7115738583 19152805 17938729
MESH:D002340 Carotid Artery Diseases Arsenic 4.6816973168 18022660
MESH:D002341 Carotid Artery Thrombosis Amiodarone 5.7218974383
MESH:D015179 Colorectal Neoplasms arsenic trioxide 1.8620501625
MESH:D023903 Coronary Restenosis arsenic trioxide 4.6912609071
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 1.8910525206
MESH:D003456 Cryptorchidism vinclozolin 4.8514966744
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 4.5615213294
MESH:D056486 Drug-Induced Liver Injury Amiodarone 2.4718218290 15265979
MESH:D004938 Esophageal Neoplasms arsenic trioxide 2.3812903497
MESH:D005234 Fatty Liver Amiodarone 9.4414986274
MESH:D005234 Fatty Liver arsenic trioxide 9.4415073043
MESH:D005534 Foot Diseases Arsenic 6.286392382
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 4.7716904648
MESH:D030342 Genetic Diseases, Inborn vinclozolin 5.5716973722
MESH:D005832 Genital Diseases, Male vinclozolin 6.0216417039
MESH:D006529 Hepatomegaly Amiodarone 4.3115265979
MESH:D006937 Hypercholesterolemia Amiodarone 4.308137927 9751232
MESH:D017488 Hyperkeratosis, Epidermolytic Arsenic 4.8517050553
MESH:D006973 Hypertension Arsenic 2.999931084 11953799 16076760
MESH:D006987 Hypesthesia Arsenic 6.2816093927
MESH:D007037 Hypothyroidism Amiodarone 5.0818020914 17991464
MESH:D007248 Infertility, Male vinclozolin 3.2916467254
MESH:D007642 Keratosis Arsenic 5.6212749816 16930632
MESH:D007938 Leukemia arsenic trioxide 3.0015070760
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 4.2217077332 12560223
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 4.9416972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 3.7214633726
MESH:D007951 Leukemia, Myeloid arsenic trioxide 4.1919077051
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 2.1920471514 16968895 19850784 16467208 17050201
MESH:D015473 Leukemia, Promyelocytic, Acute Arsenic 8.6017339181
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 8.6015622746 11468182 11161223 15748426 17869043 17649720 16891316 16823087 16966277 19035177 19225113 19642359 15213294 12018890 19075265 17217047 16330433 16331271 15336539 12712474 17107899 16112521 12679006 17712046 9834237
MESH:D015458 Leukemia, T-Cell arsenic trioxide 4.8616882451
MESH:D007984 Leydig Cell Tumor vinclozolin 5.3616417039
MESH:D008064 Lipidoses Amiodarone 3.7915342952 17567588
MESH:D008107 Liver Diseases Arsenic 2.6111134558
MESH:D008113 Liver Neoplasms Arsenic 5.2016368122
MESH:D008113 Liver Neoplasms arsenic trioxide 5.2014682389
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 2.9620377131
MESH:D008133 Long QT Syndrome Amiodarone 9.2411989578 17391786 15350150
MESH:D008133 Long QT Syndrome arsenic trioxide 9.2415213294
MESH:D008171 Lung Diseases Amiodarone 3.6212587719
MESH:D017563 Lung Diseases, Interstitial Amiodarone 5.2018516814
MESH:D008175 Lung Neoplasms Arsenic 2.7419168569 17976673 17306315
MESH:D008175 Lung Neoplasms arsenic trioxide 2.7411798837 19825857
MESH:D009101 Multiple Myeloma arsenic trioxide 3.3815949261 19417148 14977855 11468182 19549372
MESH:D009181 Mycoses Amiodarone 5.6217974566 12754197
MESH:D009182 Mycosis Fungoides arsenic trioxide 5.4018349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 3.3416105982 16882451
MESH:D017202 Myocardial Ischemia Arsenic 4.3115371236
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 4.4716624393
MESH:D009436 Neural Tube Defects Arsenic 8.2616620997
MESH:D009436 Neural Tube Defects arsenic trioxide 8.2610525206
MESH:D020078 Neurogenic Inflammation Arsenic 4.8417056641
MESH:D010051 Ovarian Neoplasms Arsenic 5.3517306315
MESH:D010051 Ovarian Neoplasms arsenic trioxide 5.3516624393 12452020 19769630
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 2.6315580305
MESH:D010235 Paraganglioma arsenic trioxide 4.6319927285
MESH:D010523 Peripheral Nervous System Diseases Arsenic 4.6816093927
MESH:D016491 Peripheral Vascular Diseases Arsenic 5.6216905509 15371236 6392382
MESH:D011297 Prenatal Exposure Delayed Effects vinclozolin 4.5318220299 19015723 18042343
MESH:D011469 Prostatic Diseases vinclozolin 5.5718220299
MESH:D011471 Prostatic Neoplasms Arsenic 3.3316140617
MESH:D011471 Prostatic Neoplasms arsenic trioxide 3.3319131511
MESH:D011472 Prostatitis vinclozolin 5.5718629315
MESH:D011507 Proteinuria Arsenic 4.4721343184
MESH:D011658 Pulmonary Fibrosis Amiodarone 2.9712832656 11597910 12490602
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 4.4716646077
OMIM:609620 SHORT QT SYNDROME 1 Amiodarone 5.7218724381
MESH:D012871 Skin Diseases Arsenic 2.8216353154 16702368 18709164 6392382 15952646 19834688 17050553 16759981 17938729 17548696 17453740
MESH:D012878 Skin Neoplasms Arsenic 3.1617029826 19538983 16251483 15504454 17976673 17050553
MESH:D013274 Stomach Neoplasms arsenic trioxide 1.8617007042
MESH:D013276 Stomach Ulcer Amiodarone 3.7418087811
MESH:D013610 Tachycardia Amiodarone 4.8011238279
MESH:D017180 Tachycardia, Ventricular Amiodarone 4.7019225199
MESH:D013959 Thyroid Diseases Amiodarone 5.4819731979
MESH:D013964 Thyroid Neoplasms arsenic trioxide 3.3919014326
MESH:D013971 Thyrotoxicosis Amiodarone 5.4219584973 18020914
MESH:D016171 Torsades de Pointes Amiodarone 12.4617467628 11989578
MESH:D016171 Torsades de Pointes arsenic trioxide 12.4615213294
MESH:D001749 Urinary Bladder Neoplasms Arsenic 5.7019322015 19429237 11144890 17976673 17306315 15987713 18640142
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 5.7012845720 11780464 20435036 12973940
MESH:D014652 Vascular Diseases Arsenic 5.3717056641
No data
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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