AutismKB 2.0

Annotation Detail for PDE4B


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:PDE4B ( DKFZp686F2182,DPDE4,MGC126529,PDE4B5,PDEIVB )
Gene Full Name: phosphodiesterase 4B, cAMP-specific
Band: 1p31.3
Quick LinksEntrez ID:5142; OMIM: 600127; Uniprot ID:PDE4B_HUMAN; ENSEMBL ID: ENSG00000184588; HGNC ID: 8781
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa00230Purine metabolism
Pathway IDPathway Name
Signaling by GPCR
Opioid Signalling
No data
No data
Pathway IDPathway Name
500841DARPP-32 events
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1907Depression
2051Leukemia
2221Behavior disease
Desease Name
Echocardiographic traits
CARDIOVASCULAR
bipolar disorder schizophrenia
PSYCH
Desease Name
Echocardiographic traits
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C554440 1-((5-(1-aminoethyl)-2-(8-methoxy-2-(triflurormethyl)-5-quinolinyl)-4-oxazolyl) carbonyl)-4-((cyclopropylcarbonyl)amino)proline ethyl ester 1-((5-(1-aminoethyl)-2-(8-methoxy-2-(triflurormethyl)-5-quinolinyl)-4-oxazolyl) carbonyl)-4-((cyclopropylcarbonyl)amino)proline ethyl ester results in decreased activity of PDE4B proteindecreases activity 20621091
C009505 4,4'-diaminodiphenylmethane 4,4'-diaminodiphenylmethane results in decreased expression of PDE4B mRNAdecreases expression 18648102
D000082 Acetaminophen Acetaminophen affects the expression of PDE4B mRNAaffects expression 17562736
D000082 Acetaminophen MAP3K5 protein affects the reaction [Acetaminophen results in increased expression of PDE4B mRNA]affects reaction|increases expression 18700144
D000420 Albuterol [Albuterol co-treated with Rolipram] results in increased expression of PDE4B mRNAaffects cotreatment|increases expression 10763856
D001151 Arsenic Arsenic results in decreased expression of PDE4B mRNAdecreases expression 16835338
D001151 Arsenic Arsenic results in decreased expression of PDE4B mRNAdecreases expression 19654921
C006632 arsenic trioxide arsenic trioxide results in decreased expression of PDE4B mRNAdecreases expression 15761015
D002251 Carbon Tetrachloride Carbon Tetrachloride affects the expression of PDE4B mRNAaffects expression 17484886
D002927 Cimetidine Cimetidine inhibits the reaction [Histamine results in increased expression of PDE4B mRNA]decreases reaction|increases expression 11131300
D003024 Clozapine Clozapine results in decreased expression of PDE4B proteindecreases expression 20222156
D003024 Clozapine Clozapine results in increased expression of PDE4B mRNAincreases expression 18222493
D003024 Clozapine Clozapine results in increased expression of PDE4B proteinincreases expression 18222493
C423222 cotylenin A cotylenin A results in increased expression of PDE4B mRNAincreases expression 16129123
C030123 coumarin coumarin results in decreased expression of PDE4B mRNAdecreases expression 18480146
C014347 decitabine [decitabine co-treated with vorinostat] affects the expression of PDE4B mRNAaffects cotreatment|affects expression 17330099
D004041 Dietary Fats Dietary Fats results in increased expression of PDE4B mRNAincreases expression 18042831
D002117 Calcitriol Calcitriol results in increased expression of PDE4B mRNAincreases expression 16002434
D004958 Estradiol Estradiol affects the expression of PDE4B mRNAaffects expression 14699072
D005047 Etoposide PDE4B protein affects the susceptibility to Etoposideaffects response to substance 16217747
D005473 Fluoxetine Fluoxetine results in decreased expression of PDE4B proteindecreases expression 20222156
D005576 Forskolin Forskolin results in increased expression of PDE4B mRNAincreases expression 15967414
D006632 Histamine Cimetidine inhibits the reaction [Histamine results in increased expression of PDE4B mRNA]decreases reaction|increases expression 11131300
D006632 Histamine Histamine results in increased expression of PDE4B mRNAincreases expression 11131300
C051890 irinotecan irinotecan metabolite results in decreased expression of PDE4B mRNAdecreases expression 15956246
C051890 irinotecan irinotecan results in decreased expression of PDE4B mRNAdecreases expression 15956246
C459562 L-826,141 L-826,141 results in decreased activity of PDE4B proteindecreases activity 15901792
D008094 Lithium Lithium results in decreased expression of PDE4B proteindecreases expression 20222156
C001478 N(6)-(delta(2)-isopentenyl)adenine N(6)-(delta(2)-isopentenyl)adenine results in increased expression of PDE4B mRNAincreases expression 16129123
C029938 nickel sulfate nickel sulfate results in increased expression of PDE4B mRNAincreases expression 16780908
C041786 palm oil palm oil results in increased expression of PDE4B mRNAincreases expression 18042831
D010634 Phenobarbital Phenobarbital results in decreased expression of PDE4B mRNAdecreases expression 19270015
D010656 Phenylephrine Phenylephrine results in increased expression of PDE4B mRNAincreases expression 18158353
C006253 pirinixic acid pirinixic acid results in decreased expression of PDE4B mRNAdecreases expression 18445702
C424423 Roflumilast Roflumilast results in decreased activity of PDE4B proteindecreases activity 15901792
D020889 Rolipram [Albuterol co-treated with Rolipram] results in increased expression of PDE4B mRNAaffects cotreatment|increases expression 10763856
C009250 sevoflurane sevoflurane affects the expression of PDE4B mRNAaffects expression 15967596
D013629 Tamoxifen Tamoxifen affects the expression of PDE4B mRNAaffects expression 14699072
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin binds to AHR protein] which results in decreased expression of PDE4B mRNAaffects binding|decreases expression 16214954
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of PDE4B mRNAdecreases expression 17337447
D013752 Tetracycline Tetracycline results in increased expression of PDE4B mRNAincreases expression 16917069
C052342 topiramate topiramate results in decreased expression of PDE4B mRNAdecreases expression 16979414
C035964 trequinsin trequinsin results in decreased activity of PDE4B proteindecreases activity 15901792
C025643 vinclozolin vinclozolin affects the expression of PDE4B mRNAaffects expression 19015723
C111237 vorinostat [decitabine co-treated with vorinostat] affects the expression of PDE4B mRNAaffects cotreatment|affects expression 17330099
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Tamoxifen 4.1514745880
MESH:D000014 Abnormalities, Drug-Induced Phenobarbital 6.996195326
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 6.9914514962 15322242 11752688
MESH:D055371 Acute Lung Injury nickel sulfate 7.9419131640 16100012 11954676 12718980
MESH:D055371 Acute Lung Injury pirinixic acid 7.9418653653
MESH:D000230 Adenocarcinoma arsenic trioxide 4.0211798837 19825857
MESH:D000230 Adenocarcinoma Estradiol 4.0211473722
MESH:D000236 Adenoma 4,4'-diaminodiphenylmethane 2.523712494
MESH:D018248 Adenoma, Liver Cell Phenobarbital 15.0017620307
MESH:D018248 Adenoma, Liver Cell pirinixic acid 15.0016434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 15.0016835633
MESH:D018246 Adrenocortical Adenoma Arsenic 4.8117306315
MESH:D000380 Agranulocytosis Clozapine 4.6714617031 12649775 16160616
MESH:D000437 Alcoholism topiramate 4.7219331489 17925516 18552399
MESH:D000544 Alzheimer Disease Lithium 3.3819621015
MESH:D000740 Anemia Tetrachlorodibenzodioxin 2.6111748828
MESH:D000799 Angioedema Acetaminophen 3.4410982225
MESH:D001008 Anxiety Disorders Fluoxetine 8.3218083778
MESH:D001008 Anxiety Disorders vinclozolin 8.3219015723
MESH:D001145 Arrhythmias, Cardiac Phenylephrine 3.7717460149
MESH:D020261 Arsenic Poisoning marker/mechanism 16835338
MESH:D020261 Arsenic Poisoning Arsenic 2.7516251483 12569548 16835338 18414634
MESH:D001161 Arteriosclerosis Dietary Fats 3.5115238619
MESH:D001249 Asthma Albuterol 5.6911991558 9949315
MESH:D001249 Asthma Histamine 5.6916387687
MESH:D050197 Atherosclerosis Arsenic 3.0112928151 19371607
MESH:D001321 Autistic Disorder marker/mechanism 18090323
MESH:D001321 Autistic Disorder Acetaminophen 2.3518445737
MESH:D001321 Autistic Disorder Fluoxetine 2.3519232924 18775368
MESH:D001660 Biliary Tract Diseases 4,4'-diaminodiphenylmethane 4.6211289319 1440618
MESH:D001714 Bipolar Disorder Lithium 4.1219153942 20338123 20046352 17594078
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 13.2416206674
MESH:D001778 Blood Coagulation Disorders pirinixic acid 13.2419483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 13.2412125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.3915340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.5115746008
MESH:D019046 Bone Marrow Neoplasms Etoposide 4.7614601052
MESH:D001919 Bradycardia Phenylephrine 4.1515306635
MESH:D001943 Breast Neoplasms Calcitriol 4.3611237771
MESH:D001943 Breast Neoplasms decitabine 4.3618320071 19208741
MESH:D001943 Breast Neoplasms Dietary Fats 4.3620435547
MESH:D001943 Breast Neoplasms Estradiol 4.3618497071 12948864 16675129 17289903 17261762 17018787 14630087 19861407
MESH:D001943 Breast Neoplasms Etoposide 4.3616322251
MESH:D001943 Breast Neoplasms Tamoxifen 4.3617261762 19142967 18984771 19221464 19103187 19189212 20390343 19189210 19288272 19410462 19066611 15668708 19289846 21138602 17440819 16202921 20135344 18629630 20065188 16873071 17049068 19084267 19244106 15565566 18821012 19011961 19487384 20544844 20005174 18855134 21152245 19115204 19155303 18815881 16273361 17893378 19200415 20859285 18997820 18351453 11161223 16818667 18425577 17242785 19059307
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 4.3620435547
MESH:D001943 Breast Neoplasms vorinostat 4.3616144943
MESH:D001986 Bronchial Spasm Histamine 5.4218298128
MESH:D002051 Burkitt Lymphoma arsenic trioxide 3.9711589617
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 4.0716111702
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 3.4016227642 18705752 16192424 3786805 15700767 16011737 15721981 16097048 16050911 10355542 15673190 16124888
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.4916835633
MESH:D002280 Carcinoma, Basal Cell Arsenic 3.3615504454 17687452
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 4.1219066611
MESH:D006528 Carcinoma, Hepatocellular 4,4'-diaminodiphenylmethane 15.607296757 3581430
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 15.603084413
MESH:D006528 Carcinoma, Hepatocellular Arsenic 15.6016507464 17306315
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 15.6014691202 15553829 16217749 11135700 15073043
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 15.6018788625
MESH:D006528 Carcinoma, Hepatocellular Estradiol 15.6016924424
MESH:D006528 Carcinoma, Hepatocellular Phenobarbital 15.6017173139 1701930 20007298 20935162 6705139
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 15.6016924424
MESH:D002291 Carcinoma, Papillary arsenic trioxide 4.4719014326
MESH:D002292 Carcinoma, Renal Cell 4,4'-diaminodiphenylmethane 2.487296757
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 3.7812490120
MESH:D002294 Carcinoma, Squamous Cell Arsenic 6.9218922899 17687452 15504454
MESH:D002294 Carcinoma, Squamous Cell Calcitriol 6.9211237771
MESH:D002294 Carcinoma, Squamous Cell decitabine 6.9219215824
MESH:D002295 Carcinoma, Transitional Cell Arsenic 8.3718640142
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 8.3717572228
MESH:D006332 Cardiomegaly Phenylephrine 6.1317287366 15728586 17124262 11754973 16170337 11179087
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 6.1316120746 18670907 18850075
MESH:D002318 Cardiovascular Diseases Arsenic 3.1815738583 19152805 17938729
MESH:D002340 Carotid Artery Diseases Arsenic 3.9818022660 16973168
MESH:D002386 Cataract Acetaminophen 2.3510977129
MESH:D002471 Cell Transformation, Neoplastic 4,4'-diaminodiphenylmethane 5.767505956
MESH:D002471 Cell Transformation, Neoplastic Estradiol 5.7618566989
MESH:D002493 Central Nervous System Diseases Phenobarbital 3.874080065
MESH:D002659 Child Development Disorders, Pervasive topiramate 3.9515650499
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 2.8316835633
MESH:D002779 Cholestasis 4,4'-diaminodiphenylmethane 6.8719486331 9022650
MESH:D002779 Cholestasis pirinixic acid 6.8719176532
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 1.9312621046 16354765 15668235 8697196 15340226
MESH:D003072 Cognition Disorders Clozapine 4.5817123785
MESH:D003110 Colonic Neoplasms decitabine 3.7217616700
MESH:D003110 Colonic Neoplasms irinotecan 3.7217725105 17287894
MESH:D015179 Colorectal Neoplasms arsenic trioxide 3.2920501625
MESH:D015179 Colorectal Neoplasms decitabine 3.2918981723
MESH:D015179 Colorectal Neoplasms irinotecan 3.2918259882 17454858 17159606 15273666 18509181 16303861 16391804
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 2.7317141729 14669216
MESH:D023903 Coronary Restenosis arsenic trioxide 3.8112609071
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 2.3310525206
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 2.3310048152 20055451 15322242
MESH:D003456 Cryptorchidism vinclozolin 3.9714966744
MESH:D003556 Cystitis Rolipram 5.8018710439
MESH:D007644 Darier Disease Lithium 5.5220338123
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 3.7315213294
MESH:D003711 Demyelinating Diseases Tamoxifen 3.9819031437
MESH:D003866 Depressive Disorder Fluoxetine 4.3215014590
MESH:D003872 Dermatitis Rolipram 5.7016442096
MESH:D017449 Dermatitis, Allergic Contact 4,4'-diaminodiphenylmethane 5.8911298694 2524372 8970840 14531868 8156756 11906362 18759878 12868966
MESH:D017449 Dermatitis, Allergic Contact nickel sulfate 5.8916823706 11298694 16780908
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.2418249437
MESH:D003877 Dermatitis, Contact 4,4'-diaminodiphenylmethane 3.133621924 2952479
MESH:D018500 Diabetes Insipidus, Nephrogenic Lithium 5.3619244398
MESH:D003924 Diabetes Mellitus, Type 2 Clozapine 9.4616402076
MESH:D003924 Diabetes Mellitus, Type 2 coumarin 9.4619647726
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 9.4617107852
MESH:D003924 Diabetes Mellitus, Type 2 topiramate 9.4616979414
MESH:D003928 Diabetic Nephropathies Estradiol 7.7419279558
MESH:D003928 Diabetic Nephropathies Tamoxifen 7.7419279558
MESH:D003967 Diarrhea vorinostat 4.1320479100
MESH:D006970 Disorders of Excessive Somnolence Clozapine 5.1515331141
MESH:D056486 Drug-Induced Liver Injury 4,4'-diaminodiphenylmethane 10.611440618 18289764 9653073 9022650 9328219 18692083 11289319 18648102 6482804 16192314 8291058 6679447 7440962
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 10.6111834606 12705907 16393943 11421492 12958197 19416960 17562736 17522070 19085960 16109766 12153990 14725611 11739529 18071297 19923254 11461765 16227642 15968718 16177239 16081117 19370779 11287661 18713872 10915739 11529661 16781746 12392966 19739265 12594235 17906064 19164858 11743745 19420014 14550746 14986274 10774834 2444490 16485898 15619225 12540782 10663392
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 10.6116227642 3732212 21278145 7179309 4309450 3786805 9327722 7120509 2869522 6884620 19336974 10092053 11566570 15998439 17522070 10915739 19085960 6623471 15968718 15027814 16177239 7440962
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 10.6120420201
MESH:D056486 Drug-Induced Liver Injury Tetracycline 10.6117522070
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 3.7019426721
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.4711462148
MESH:D050171 Dyslipidemias Clozapine 7.9216402076
MESH:D050171 Dyslipidemias Dietary Fats 7.9218367378
MESH:D004417 Dyspnea Albuterol 5.4220016425
MESH:D004421 Dystonia Phenobarbital 3.641851702
MESH:D004487 Edema Cimetidine 13.7119703484
MESH:D004487 Edema Fluoxetine 13.7112798668
MESH:D004487 Edema pirinixic acid 13.7112083418
MESH:D004487 Edema Tetrachlorodibenzodioxin 13.7111000095 12711302
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 3.5018230668 15322242 16714409
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Calcitriol 7.9815138306
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 7.9819031437
MESH:D004701 Endocrine Gland Neoplasms decitabine 4.7119294695
MESH:D016889 Endometrial Neoplasms Estradiol 6.5218566989 19148513 11473722
MESH:D016889 Endometrial Neoplasms Tamoxifen 6.5217893378 19155303 16202921 20544844
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 2.689294722 10568697
MESH:D004802 Eosinophilia Histamine 4.6712689652
MESH:D004831 Epilepsies, Myoclonic Phenobarbital 3.723659116
MESH:D004828 Epilepsies, Partial Phenobarbital 3.473922381 11558140
MESH:D004827 Epilepsy Phenobarbital 6.4820417680
MESH:D004827 Epilepsy topiramate 6.4819148780
MESH:D004832 Epilepsy, Absence Phenobarbital 3.216401628
MESH:D017029 Epilepsy, Complex Partial Phenobarbital 3.877750514
MESH:D004833 Epilepsy, Temporal Lobe topiramate 5.8716499746
MESH:D004830 Epilepsy, Tonic-Clonic Phenobarbital 3.633659116
MESH:D004938 Esophageal Neoplasms 4,4'-diaminodiphenylmethane 4.093581430
MESH:D004938 Esophageal Neoplasms arsenic trioxide 4.0912903497
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 2.7211564622
MESH:D005221 Fatigue vorinostat 5.2020479100
MESH:D005234 Fatty Liver arsenic trioxide 26.1615073043
MESH:D005234 Fatty Liver Carbon Tetrachloride 26.1617595544 12795759 61145 15959796 19224547 12631006 16045604 16239168
MESH:D005234 Fatty Liver Dietary Fats 26.1617967931 19551842 19004024 18296743
MESH:D005234 Fatty Liver pirinixic acid 26.1619236843 20131406
MESH:D005234 Fatty Liver Tamoxifen 26.1619224547 14986274
MESH:D005234 Fatty Liver Tetracycline 26.1616917069 19224547
MESH:D052776 Female Urogenital Diseases Tamoxifen 2.9916709447
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.0711858732
MESH:D005350 Fibroma 4,4'-diaminodiphenylmethane 4.626705139
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 4.1314745880
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 3.7919069698
MESH:D005355 Fibrosis Albuterol 18.0915467267
MESH:D005355 Fibrosis Carbon Tetrachloride 18.0918705752
MESH:D005355 Fibrosis Dietary Fats 18.0918296743
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 18.0920067830
MESH:D005534 Foot Diseases Arsenic 5.166392382
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 3.8916904648
MESH:D005739 Gas Poisoning Albuterol 5.8020016425
MESH:D005756 Gastritis Acetaminophen 3.2716983495
MESH:D030342 Genetic Diseases, Inborn vinclozolin 4.5416973722
MESH:D005832 Genital Diseases, Male vinclozolin 4.9016417039
MESH:D006042 Goiter 4,4'-diaminodiphenylmethane 3.677505956
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.1910696789
MESH:D006258 Head and Neck Neoplasms decitabine 3.2219215824
MESH:D006330 Heart Defects, Congenital Lithium 6.3119638421
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 6.3110048152 11294989
MESH:D006333 Heart Failure pirinixic acid 2.2920558911
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 2.9811000095
MESH:D006505 Hepatitis 4,4'-diaminodiphenylmethane 7.986705139
MESH:D006505 Hepatitis Carbon Tetrachloride 7.9819900420 19110552
MESH:D006529 Hepatomegaly Phenobarbital 12.1616109766
MESH:D006529 Hepatomegaly pirinixic acid 12.1618467677 16221962 19772884 19176532
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 12.1615340226 16120746 12621046
MESH:D006558 Herpes Genitalis Estradiol 4.6315709030
MESH:D006561 Herpes Simplex Etoposide 4.1710809021
MESH:D006689 Hodgkin Disease Etoposide 3.5516135485 16200630 15147373 18180244 17606976
MESH:D019584 Hot Flashes Estradiol 9.2117088409
MESH:D019584 Hot Flashes Fluoxetine 9.2114716179
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.6418606429 15340226 8697196 16959395 16354765
MESH:D006930 Hyperalgesia Acetaminophen 2.3916870215
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 4.1416899240
MESH:D006937 Hypercholesterolemia Dietary Fats 3.2421332399
MESH:D006943 Hyperglycemia pirinixic acid 2.8420558911
MESH:D017488 Hyperkeratosis, Epidermolytic Arsenic 4.1117050553
MESH:D006948 Hyperkinesis Clozapine 4.5216046005
MESH:D006949 Hyperlipidemias Dietary Fats 3.2621332399
MESH:D006965 Hyperplasia 4,4'-diaminodiphenylmethane 3.5515034207
MESH:D006973 Hypertension Arsenic 7.7716076760 9931084 11953799
MESH:D006973 Hypertension Phenylephrine 7.778949925 12717712
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 7.7718850075 18670907
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 3.7015338365
MESH:D006984 Hypertrophy Phenylephrine 4.2018502941 12791704
MESH:D006987 Hypesthesia Arsenic 5.1616093927
MESH:D007077 Ileal Diseases Rolipram 6.0018306037
MESH:D007248 Infertility, Male decitabine 6.0417581917
MESH:D007248 Infertility, Male vinclozolin 6.0416467254
MESH:D007249 Inflammation Dietary Fats 10.2620412841
MESH:D007249 Inflammation Fluoxetine 10.2612798668
MESH:D007249 Inflammation Tamoxifen 10.2619457130
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 10.2612200463 12878042
MESH:D007333 Insulin Resistance Dietary Fats 10.7818457598 11836018
MESH:D007333 Insulin Resistance Estradiol 10.7816393666 16627594
MESH:D007333 Insulin Resistance pirinixic acid 10.7816306350
MESH:D007565 Jaundice 4,4'-diaminodiphenylmethane 4.628074119 9022650
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 2.9816580747
MESH:D007579 Jejunal Diseases Rolipram 6.0018306037
MESH:D007642 Keratosis Arsenic 4.6012749816 16930632
MESH:D007674 Kidney Diseases Acetaminophen 5.1115629191 12587719
MESH:D007674 Kidney Diseases Estradiol 5.1115618244
MESH:D007680 Kidney Neoplasms 4,4'-diaminodiphenylmethane 10.576582329
MESH:D007680 Kidney Neoplasms Estradiol 10.5715610895
MESH:D007680 Kidney Neoplasms Tamoxifen 10.5718625569
MESH:D007859 Learning Disorders sevoflurane 4.3919212262
MESH:D007938 Leukemia arsenic trioxide 5.7715070760
MESH:D007938 Leukemia decitabine 5.7719235587 18980019
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 3.4412560223 17077332
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 3.9116972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 3.1414633726
MESH:D007951 Leukemia, Myeloid arsenic trioxide 8.4219077051
MESH:D007951 Leukemia, Myeloid decitabine 8.4218454857 17236224 19117987
MESH:D015470 Leukemia, Myeloid, Acute marker/mechanism 17330099
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 3.7216968895 17050201 20471514 16467208 19850784
MESH:D015470 Leukemia, Myeloid, Acute decitabine 3.7218460780 18704418 18206229 19387464 19010910 17679729
MESH:D015477 Leukemia, Myelomonocytic, Chronic decitabine 5.0618055864
MESH:D015473 Leukemia, Promyelocytic, Acute Arsenic 6.9117339181
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 6.9116823087 11468182 15622746 16966277 17649720 15336539 17869043 17217047 19075265 12018890 15213294 16331271 16891316 19225113 9834237 15748426 17712046 16112521 19642359 19035177 17107899 11161223 12679006 16330433 12712474
MESH:D015458 Leukemia, T-Cell arsenic trioxide 3.9816882451
MESH:D007984 Leydig Cell Tumor vinclozolin 4.3416417039
MESH:D008064 Lipidoses Clozapine 11.7517567588
MESH:D008064 Lipidoses Fluoxetine 11.7515342952 17567588
MESH:D008064 Lipidoses Tamoxifen 11.7517567588 15342952
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 9.7321278145 16943688 11408273 16221502 17334410 11903743 17174718 16239168 17157831
MESH:D008103 Liver Cirrhosis Dietary Fats 9.7318296743
MESH:D008103 Liver Cirrhosis Phenobarbital 9.7321047994
MESH:D008105 Liver Cirrhosis, Biliary 4,4'-diaminodiphenylmethane 2.959327722 15034207
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 6.1018395095 12586293 16015684 12445421 18277467 18187930 18420326 16011737 14716833 18339082 12389079 15362042 17900296 10355542 11481614 17766677 15931870 18166357 18472332 18412020 15673190 16192424 15730626 17557913 17922224 15123356 18006644 18481824 14716496 17805973 14748882 12898905 17869086 17565644 15370692 16027843 18472094 17631135 12546737 12632512 15818738 18418968 17714472 17721639 12649538 15338365 20821823 15057751 12445418 18705752 15925388 15893842 14724832 16116963 16638106 15650968 17823541 18395914 14512876 15876570 12666154 17944888 18251166 18317297 17761835 18279442 16097048 18210741 14620537 18205269 18376398 15959796 18054572 17976157 12609069 18429990 17698563 18263696 17708605 12958196 16136751 12632514 16033810 16248980 17481882 15996030 15052691 17525996 12741479 12667390 13678700 18156304 17640975
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 6.1014716833 14659978
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 6.1015474484
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 6.1018564211
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 6.1012878042
MESH:D008107 Liver Diseases Acetaminophen 8.4219014921 16611625 11587558 16610002 19460945 12969438 19784758 12587719
MESH:D008107 Liver Diseases Arsenic 8.4211134558
MESH:D008107 Liver Diseases Carbon Tetrachloride 8.4216964402 16246199 17285989 15720792 15830285
MESH:D008107 Liver Diseases Phenobarbital 8.4219363144
MESH:D017093 Liver Failure Carbon Tetrachloride 3.7815123358
MESH:D017114 Liver Failure, Acute Acetaminophen 8.2816871587 17185352
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 8.2814706259 16899240
MESH:D008113 Liver Neoplasms Arsenic 19.4116368122
MESH:D008113 Liver Neoplasms arsenic trioxide 19.4114682389
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 19.4119294768
MESH:D008113 Liver Neoplasms Phenobarbital 19.4119482888 19812893 8742319 21047994 15975961 19073162
MESH:D008113 Liver Neoplasms pirinixic acid 19.4116377806 15890375 20007298
MESH:D008113 Liver Neoplasms Tamoxifen 19.4116684651
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 19.4116984957
MESH:D008114 Liver Neoplasms, Experimental 4,4'-diaminodiphenylmethane 15.98598648 1399818 6587162 3712494
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 15.9820377131
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 15.9815583823 12014681
MESH:D008114 Liver Neoplasms, Experimental Phenobarbital 15.9817172636 18308698 1399818 6150874 2563599
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 15.9812151625
MESH:D008133 Long QT Syndrome arsenic trioxide 3.0515213294
MESH:D008175 Lung Neoplasms Arsenic 4.4117976673 17306315 19168569
MESH:D008175 Lung Neoplasms arsenic trioxide 4.4111798837 19825857
MESH:D008175 Lung Neoplasms Tamoxifen 4.4118625569
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 4.4111884234 19555203
MESH:D008223 Lymphoma decitabine 6.9619470736
MESH:D008223 Lymphoma Etoposide 6.9612854902 12556972
MESH:D016410 Lymphoma, T-Cell, Cutaneous vorinostat 5.3020479100
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 3.3719428831
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 5.1211408345 11807958 16891317 17203775
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 5.1219196723 14580682 16827153 11731420 19196722
MESH:D020149 Manganese Poisoning Estradiol 11.3119453300
MESH:D020149 Manganese Poisoning Tamoxifen 11.3119453300
MESH:D008545 Melanoma decitabine 4.8616505122 17785578
MESH:D008545 Melanoma Histamine 4.8617709802
MESH:D008545 Melanoma Tamoxifen 4.8619393235 12393984
MESH:D018328 Melanoma, Amelanotic Tamoxifen 3.7915990972
MESH:D008546 Melanoma, Experimental Acetaminophen 3.1819513568
MESH:D008569 Memory Disorders sevoflurane 4.3819212262
MESH:D001523 Mental Disorders Clozapine 7.3016856516
MESH:D001523 Mental Disorders Fluoxetine 7.3016856516
MESH:D024821 Metabolic Syndrome X Clozapine 4.0919142101
MESH:D008881 Migraine Disorders topiramate 4.3018759728 18765137 16942474 18803445
MESH:D052016 Mucositis irinotecan 4.6117159606
MESH:D009101 Multiple Myeloma arsenic trioxide 6.4419417148 15949261 19549372 11468182 14977855
MESH:D009101 Multiple Myeloma decitabine 6.4418172295
MESH:D009135 Muscular Diseases pirinixic acid 3.1216239165
MESH:D009182 Mycosis Fungoides arsenic trioxide 4.2718349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 6.7316882451 16105982
MESH:D009190 Myelodysplastic Syndromes decitabine 6.7319010910 16882708 19157545 18608210
MESH:D009203 Myocardial Infarction Lithium 5.4916288908
MESH:D009203 Myocardial Infarction pirinixic acid 5.4919151258
MESH:D017202 Myocardial Ischemia Arsenic 7.9715371236
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 7.9712213967
MESH:D015428 Myocardial Reperfusion Injury Estradiol 7.2516810080
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 7.2516411023
MESH:D020191 Myoclonic Epilepsies, Progressive Phenobarbital 4.0817484760
MESH:D009207 Myoclonus Fluoxetine 5.488041377
MESH:D009325 Nausea vorinostat 5.1220479100
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 3.5916624393
MESH:D009362 Neoplasm Metastasis 4,4'-diaminodiphenylmethane 8.563581430
MESH:D009362 Neoplasm Metastasis irinotecan 8.5618259882
MESH:D009362 Neoplasm Metastasis Tamoxifen 8.5619393235
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.3819410462
MESH:D009369 Neoplasms decitabine 4.3517925555 19116145 19470736
MESH:D009369 Neoplasms pirinixic acid 4.3517405874
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 3.6019189210 19196722 19200415
MESH:D009389 Neovascularization, Pathologic Estradiol 3.3417289903
MESH:D009395 Nephritis, Interstitial Tetracycline 4.389884423
MESH:D009421 Nervous System Malformations Estradiol 8.2211399458 16427766
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 8.2214600291
MESH:D009436 Neural Tube Defects 4,4'-diaminodiphenylmethane 10.676679447
MESH:D009436 Neural Tube Defects Arsenic 10.6716620997
MESH:D009436 Neural Tube Defects arsenic trioxide 10.6710525206
MESH:D009447 Neuroblastoma irinotecan 3.278761367
MESH:D019636 Neurodegenerative Diseases Acetaminophen 2.5518514411
MESH:D017599 Neuroectodermal Tumors irinotecan 4.348761367
MESH:D020078 Neurogenic Inflammation Arsenic 4.0117056641
MESH:D009765 Obesity Clozapine 6.8219142110 18515891
MESH:D009765 Obesity Dietary Fats 6.8221332399 17217161 18674790 16723640 18457598 11836018 20518802 19632207 20132043
MESH:D009765 Obesity pirinixic acid 6.8220558911
MESH:D009771 Obsessive-Compulsive Disorder Fluoxetine 5.0920418887
MESH:D009784 Occupational Diseases 4,4'-diaminodiphenylmethane 3.084026338 6482804
MESH:D009902 Optic Neuritis 4,4'-diaminodiphenylmethane 4.623988306
MESH:D010018 Osteomalacia Phenobarbital 3.9717016548
MESH:D010051 Ovarian Neoplasms Arsenic 10.1817306315
MESH:D010051 Ovarian Neoplasms arsenic trioxide 10.1812452020 19769630 16624393
MESH:D010051 Ovarian Neoplasms decitabine 10.1819331143 19259094
MESH:D010051 Ovarian Neoplasms Estradiol 10.1819401270
MESH:D010146 Pain Acetaminophen 6.0716870215
MESH:D010146 Pain Fluoxetine 6.0712798668
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 11.1115580305
MESH:D010190 Pancreatic Neoplasms decitabine 11.1119294695
MESH:D010190 Pancreatic Neoplasms Etoposide 11.1119003803
MESH:D010190 Pancreatic Neoplasms Phenobarbital 11.1116965848
MESH:D010195 Pancreatitis Cimetidine 4.9310484002
MESH:D010212 Papilloma 4,4'-diaminodiphenylmethane 3.107296757
MESH:D010235 Paraganglioma arsenic trioxide 3.8019927285
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 3.8512520081
MESH:D010391 Pemphigoid, Bullous Tetracycline 5.0311026799
MESH:D010523 Peripheral Nervous System Diseases Arsenic 3.8116093927
MESH:D016491 Peripheral Vascular Diseases Arsenic 4.6016905509 15371236 6392382
MESH:D010787 Photosensitivity Disorders 4,4'-diaminodiphenylmethane 4.076228378
MESH:D020774 Pick Disease of the Brain Fluoxetine 5.618041377
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.1818163543
MESH:D011230 Precancerous Conditions Phenobarbital 3.292563599
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 8.1811118676 11896295 11222880 11399792
MESH:D011297 Prenatal Exposure Delayed Effects vinclozolin 8.1818042343 19015723 18220299
MESH:D055728 Primary Myelofibrosis decitabine 4.3417616702
MESH:D017096 Prion Diseases Tetracycline 5.0210903871
MESH:D011469 Prostatic Diseases vinclozolin 4.5418220299
MESH:D011470 Prostatic Hyperplasia Calcitriol 4.3815572423
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 3.5320887781
MESH:D011471 Prostatic Neoplasms Arsenic 2.0416140617
MESH:D011471 Prostatic Neoplasms arsenic trioxide 2.0419131511
MESH:D011471 Prostatic Neoplasms Calcitriol 2.0412479363 18247401 16644109 16289102 15754350
MESH:D011471 Prostatic Neoplasms Estradiol 2.0416740699
MESH:D011471 Prostatic Neoplasms Etoposide 2.0417172428
MESH:D011471 Prostatic Neoplasms Tamoxifen 2.0415067354
MESH:D011471 Prostatic Neoplasms vorinostat 2.0417218635
MESH:D011472 Prostatitis vinclozolin 4.5418629315
MESH:D011507 Proteinuria Arsenic 3.6421343184
MESH:D019310 Pseudolymphoma Phenobarbital 4.0912752131
MESH:D011618 Psychotic Disorders Clozapine 3.9015331141
MESH:D015427 Reperfusion Injury pirinixic acid 2.1919058328
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.4618990726
MESH:D012162 Retinal Degeneration 4,4'-diaminodiphenylmethane 3.083692021
MESH:D012208 Rhabdomyosarcoma decitabine 4.0419155313
MESH:D012220 Rhinitis Histamine 4.6412689652
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 9.2016646077
MESH:D012512 Sarcoma, Ewing's Etoposide 9.2014601052
MESH:D012559 Schizophrenia Clozapine 2.6818806925 20168265 16141801 20521326 17123785 17726453 11151749 17667964 11763009 20107430 20521320 20452607 19369910 20580759 18855531
MESH:D012640 Seizures Lithium 8.6619660546
MESH:D012640 Seizures Phenobarbital 8.664039156 11442880 16876388 3137016
MESH:D012640 Seizures topiramate 8.6616499746
MESH:D003294 Seizures, Febrile Phenobarbital 4.436407741
MESH:D020230 Serotonin Syndrome Fluoxetine 5.508704074
MESH:D012852 Sinusitis Phenylephrine 4.317327846
MESH:D012871 Skin Diseases marker/mechanism 16835338
MESH:D012871 Skin Diseases Arsenic 2.6419834688 16759981 15952646 16353154 17938729 17548696 18709164 17453740 17050553 6392382 16702368
MESH:D012878 Skin Neoplasms Arsenic 5.0615504454 16251483 19538983 17050553 17976673 17029826
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 5.0616192470
MESH:D013088 Spermatocele Tamoxifen 3.8916709447
MESH:D013119 Spinal Cord Injuries Tamoxifen 3.6419457130
MESH:D013226 Status Epilepticus Lithium 5.3919430551 19570321 19951488
MESH:D013272 Stomach Diseases Rolipram 5.4115038085
MESH:D013274 Stomach Neoplasms arsenic trioxide 3.2517007042
MESH:D013274 Stomach Neoplasms decitabine 3.2519037991
MESH:D013274 Stomach Neoplasms irinotecan 3.2515723263
MESH:D013276 Stomach Ulcer Rolipram 4.6314567935
MESH:D013921 Thrombocytopenia vorinostat 4.6320479100
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.5012697716
MESH:D013964 Thyroid Neoplasms 4,4'-diaminodiphenylmethane 14.661399818 7505956 3712494 6582329 6587162
MESH:D013964 Thyroid Neoplasms arsenic trioxide 14.6619014326
MESH:D013964 Thyroid Neoplasms decitabine 14.6617967635
MESH:D013964 Thyroid Neoplasms Phenobarbital 14.661399818
MESH:D013978 Tibial Fractures Estradiol 4.2819048282
MESH:D016171 Torsades de Pointes arsenic trioxide 3.5715213294
MESH:D001749 Urinary Bladder Neoplasms 4,4'-diaminodiphenylmethane 14.048074119
MESH:D001749 Urinary Bladder Neoplasms Arsenic 14.0419322015 17306315 17976673 18640142 11144890 19429237 15987713
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 14.0411780464 20435036 12973940 12845720
MESH:D001749 Urinary Bladder Neoplasms decitabine 14.0417616700 19087683
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 14.048653321 16712894 17572228
MESH:D014581 Urticaria Acetaminophen 7.9210982225
MESH:D014581 Urticaria Histamine 7.9218298128
MESH:D014604 Uveal Neoplasms decitabine 4.5117785578
MESH:D014652 Vascular Diseases Arsenic 4.3417056641
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.1912125929
MESH:D014689 Venous Insufficiency coumarin 5.3712708602
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 3.8515886252
MESH:D015430 Weight Gain Clozapine 8.7320564506 16141801 20521320 17502770 16402076 20107430
MESH:D015430 Weight Gain Dietary Fats 8.7316723640
MESH:D015431 Weight Loss Clozapine 4.6817933447
Pathway ID Pathway Name
REACT:15295 Opioid Signalling
KEGG:00230 Purine metabolism
REACT:14797 Signaling by GPCR
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA33129
    • No data
    Releated disease ID Related disease Name
    PA444987Multiple Sclerosis
    PA447321Depressive Disorder, Major
    PA446155Precursor Cell Lymphoblastic Leukemia-Lymphoma
    PA447216Schizophrenia
    Releated drug ID Related drug Name
    PA449233desipramine
    PA449673fluoxetine
    Drug Bank Top
    Drugbank ID Action Drug Name Description
    DB00131 - Adenosine monophosphate Dietary supplement;Micronutrient
    DB00201 antagonist Wigraine Tab Central Nervous System Stimulants;Anorexigenic Agents;Phosphodiesterase Inhibitors
    DB00277 antagonist Theophylline rougier elixir Vasodilator Agents;Phosphodiesterase Inhibitors;Bronchodilator Agents;Respiratory Smooth Muscle Relaxants
    DB00651 antagonist Dyphylline Vasodilator Agents;Phosphodiesterase Inhibitors;Bronchodilator Agents;Respiratory Smooth Muscle Relaxants
    DB00806 antagonist Pentoxifylline Free Radical Scavengers;Vasodilator Agents;Platelet Aggregation Inhibitors;Phosphodiesterase Inhibitors;Radiation-Protective Agents;Hematologic Agents;Hemorrheologic Agents
    DB00824 antagonist Enprofylline Anti-Asthmatic Agents;Antiarrhythmic Agents;Bronchodilator Agents
    DB00920 antagonist Ketotifen Antipruritics;Anti-Allergic Agents;Histamine H1 Antagonists
    DB01088 agonist Iloprost Antihypertensive Agents
    DB01113 antagonist Papaverine Vasodilator Agents;Phosphodiesterase Inhibitors
    DB01412 antagonist Theobromine Vasodilator Agents;Bronchodilator Agents
    DB01427 antagonist Amrinone Vasodilator Agents;Phosphodiesterase Inhibitors;Cardiotonic Agents;Calcium Channel Blockers
    DB01647 - (R)-Mesopram
    DB01791 - Piclamilast Phosphodiesterase Inhibitors
    DB01954 - 4-[3-(Cyclopentyloxy)-4-Methoxyphenyl]-2-Pyrrolidinone Phosphodiesterase Inhibitors;Antidepressive Agents
    DB01959 - 3,5-Dimethyl-1-(3-Nitrophenyl)-1h-Pyrazole-4-Carboxylic Acid Ethyl Ester
    DB02660 - Filaminast
    DB03349 - 8-Bromo-Adenosine-5'-Monophosphate
    DB03606 inhibitor (S)-Rolipram Phosphodiesterase Inhibitors;Antidepressive Agents
    DB03807 - 1-(2-Chlorophenyl)-3,5-Dimethyl-1h-Pyrazole-4-Carboxylic Acid Ethyl Ester
    DB03849 - Cis-4-Cyano-4-[3-(Cyclopentyloxy)-4-Methoxyphenyl]Cyclohexanecarboxylic Acid
    DB04149 inhibitor (R)-Rolipram Phosphodiesterase Inhibitors;Antidepressive Agents
    DB04530 - S,S-(2-Hydroxyethyl)Thiocysteine
    DB05266 antagonist Ibudilast Vasodilator Agents;Platelet Aggregation Inhibitors;Phosphodiesterase Inhibitors;Bronchodilator Agents
    DB06909 - 1-ethyl-N-(phenylmethyl)-4-(tetrahydro-2H-pyran-4-ylamino)-1H-pyrazolo[3,4-b]pyridine-5-carboxamide
    DB08299 - 4-[8-(3-nitrophenyl)-1,7-naphthyridin-6-yl]benzoic acid
    No data
    No data
    No data

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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