AutismKB 2.0

Annotation Detail for ISYNA1


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Basic Information Top
Gene Symbol:ISYNA1 ( INO1,INOS,IPS )
Gene Full Name: inositol-3-phosphate synthase 1
Band: 19p13.11
Quick LinksEntrez ID:51477; OMIM: 611670; Uniprot ID:INO1_HUMAN; ENSEMBL ID: ENSG00000105655; HGNC ID: 29821
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Pathway IDPathway Name
PWY-2301myo-inositol biosynthesis
Pathway IDPathway Name
hsa00562Inositol phosphate metabolism
hsa01100Metabolic pathways
No data
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No data
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000082 Acetaminophen Acetaminophen affects the expression of ISYNA1 mRNAaffects expression 17562736
D016604 Aflatoxin B1 Aflatoxin B1 affects the expression of ISYNA1 proteinaffects expression 20106945
D000638 Amiodarone Amiodarone affects the expression of ISYNA1 mRNAaffects expression 19483382
C015001 arsenite arsenite results in decreased expression of ISYNA1 mRNAdecreases expression 18929588
C015001 arsenite TRP53 protein affects the reaction [arsenite results in decreased expression of ISYNA1 mRNA]affects reaction|decreases expression 18929588
D001553 Benzbromarone Benzbromarone affects the expression of ISYNA1 mRNAaffects expression 19483382
D001564 Benzo(a)pyrene Benzo(a)pyrene results in increased expression of ISYNA1 mRNAincreases expression 20064835
20106945
D002994 Clofibrate Clofibrate affects the expression of ISYNA1 mRNAaffects expression 19483382
C030123 coumarin coumarin results in increased expression of ISYNA1 mRNAincreases expression 18480146
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of ISYNA1 mRNAincreases expression 12072388
D004997 Ethinyl Estradiol Ethinyl Estradiol affects the expression of ISYNA1 mRNAaffects expression 17351261
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of ISYNA1 mRNAincreases expression 17108234
D005001 Ethionine Ethionine affects the expression of ISYNA1 mRNAaffects expression 19483382
D009853 Omeprazole Omeprazole affects the expression of ISYNA1 mRNAaffects expression 19483382
D010634 Phenobarbital NR1I3 protein affects the reaction [Phenobarbital results in increased expression of ISYNA1 mRNA]affects reaction|increases expression 19482888
D010634 Phenobarbital Phenobarbital results in increased expression of ISYNA1 mRNAincreases expression 19482888
C006253 pirinixic acid pirinixic acid affects the expression of ISYNA1 mRNAaffects expression 19483382
D011441 Propylthiouracil Propylthiouracil affects the expression of ISYNA1 mRNAaffects expression 19483382
D012643 Selenium Selenium results in increased expression of ISYNA1 mRNAincreases expression 19244175
D013853 Thioacetamide Thioacetamide affects the expression of ISYNA1 mRNAaffects expression 19483382
D014212 Tretinoin Tretinoin results in increased expression of ISYNA1 mRNAincreases expression 16249480
D014212 Tretinoin Tretinoin results in decreased expression of ISYNA1 mRNAdecreases expression 16604517
D014635 Valproic Acid Valproic Acid results in increased expression of ISYNA1 mRNAincreases expression 19101580
D014810 Vitamin E Vitamin E results in increased expression of ISYNA1 mRNAincreases expression 19244175
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Phenobarbital 8.336195326
MESH:D000014 Abnormalities, Drug-Induced Valproic Acid 8.338875741
MESH:D000015 Abnormalities, Multiple Valproic Acid 3.8619490988
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.8917505938
MESH:D055371 Acute Lung Injury pirinixic acid 3.0518653653
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 4.1220127859 20464547
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 4.1214692618
MESH:D000236 Adenoma Benzo(a)pyrene 2.616695378
MESH:D018248 Adenoma, Liver Cell Phenobarbital 9.9217620307
MESH:D018248 Adenoma, Liver Cell pirinixic acid 9.9216434500
MESH:D000505 Alopecia Tretinoin 3.5615955085
MESH:D000550 Amblyopia Valproic Acid 5.1817688650
MESH:D000799 Angioedema Acetaminophen 3.7910982225
MESH:D001008 Anxiety Disorders Valproic Acid 3.5217497229
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 4.0119183758
MESH:D001145 Arrhythmias, Cardiac Amiodarone 3.7420041841 18218290 18057881
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 3.4011256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 7.0715885639
MESH:D001169 Arthritis, Experimental Tretinoin 7.0716412693
MESH:D001172 Arthritis, Rheumatoid Tretinoin 2.2516292516
MESH:D001249 Asthma Tretinoin 2.3216456186
MESH:D001281 Atrial Fibrillation Amiodarone 3.8519698954 18651412
MESH:D001321 Autistic Disorder Acetaminophen 1.8518445737
MESH:D001321 Autistic Disorder Valproic Acid 1.8520603192 18396377 17507914 19232924 18985861 18775368 18316065 19460635 15238991 18177632 18558336 16609825 17157402 18940202 17688650
MESH:D001471 Barrett Esophagus Tretinoin 4.3416935849
MESH:D001714 Bipolar Disorder Valproic Acid 3.0417594078 20046352
MESH:D001778 Blood Coagulation Disorders Amiodarone 57.3719483382
MESH:D001778 Blood Coagulation Disorders Benzbromarone 57.3719483382
MESH:D001778 Blood Coagulation Disorders Clofibrate 57.3719483382
MESH:D001778 Blood Coagulation Disorders Ethionine 57.3719483382
MESH:D001778 Blood Coagulation Disorders Omeprazole 57.3719483382
MESH:D001778 Blood Coagulation Disorders pirinixic acid 57.3719483382
MESH:D001778 Blood Coagulation Disorders Propylthiouracil 57.3719483382
MESH:D001778 Blood Coagulation Disorders Thioacetamide 57.3719483382
MESH:D001778 Blood Coagulation Disorders Tretinoin 57.3716206674 16197459
MESH:D001848 Bone Diseases, Developmental Valproic Acid 3.368888407
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 2.1220146248 17474063
MESH:D001943 Breast Neoplasms Tretinoin 2.1216166294 16443354 16873071
MESH:D001997 Bronchopulmonary Dysplasia Tretinoin 4.5316813970
MESH:D002252 Carbon Tetrachloride Poisoning Vitamin E 3.8716050911
MESH:D003528 Carcinoma, Adenoid Cystic marker/mechanism 16762588
MESH:D018236 Carcinoma, Embryonal Tretinoin 5.1016168501
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 11.273084413
MESH:D006528 Carcinoma, Hepatocellular Aflatoxin B1 11.2721507988 12907637 12619106
MESH:D006528 Carcinoma, Hepatocellular Benzbromarone 11.271701930
MESH:D006528 Carcinoma, Hepatocellular Phenobarbital 11.2717173139 1701930 6705139 20007298 20935162
MESH:D006528 Carcinoma, Hepatocellular Thioacetamide 11.2717997003
MESH:D006528 Carcinoma, Hepatocellular Tretinoin 11.271917145
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 4.5020419170
MESH:D002294 Carcinoma, Squamous Cell Tretinoin 4.5016051514 16096774
MESH:D002311 Cardiomyopathy, Dilated Amiodarone 2.8719225199 15710769
MESH:D002341 Carotid Artery Thrombosis Amiodarone 5.0218974383
MESH:D002386 Cataract Acetaminophen 7.1010977129
MESH:D002386 Cataract Tretinoin 7.1017460283
MESH:D002471 Cell Transformation, Neoplastic Clofibrate 3.481399818
MESH:D002493 Central Nervous System Diseases Phenobarbital 4.194080065
MESH:D018290 Cervical Intraepithelial Neoplasia Tretinoin 4.5316129372
MESH:D002637 Chest Pain Omeprazole 5.0515447763
MESH:D002659 Child Development Disorders, Pervasive Valproic Acid 2.6820734317
MESH:D018281 Cholangiocarcinoma Thioacetamide 4.2318291259
MESH:D002779 Cholestasis Ethinyl Estradiol 7.5816919318 17110522 16105132 11677210 17681005 15861022 17333356
MESH:D002779 Cholestasis pirinixic acid 7.5819176532
MESH:D002822 Choriocarcinoma Tretinoin 5.1016461808
MESH:D002972 Cleft Palate Tretinoin 2.649407595
MESH:D003092 Colitis Selenium 9.2817936198
MESH:D003092 Colitis Tretinoin 9.2817035595
MESH:D003110 Colonic Neoplasms arsenite 2.5815037631
MESH:D019465 Craniofacial Abnormalities Tretinoin 3.819224671 16925845 14991402 17551590 9125849 10589399 9211117 8800419 9142499 9664655
MESH:D019465 Craniofacial Abnormalities Valproic Acid 3.818888407 17688650 16575769
MESH:D019465 Craniofacial Abnormalities Vitamin E 3.8119769572
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.3918249437
MESH:D003924 Diabetes Mellitus, Type 2 coumarin 3.1819647726
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 11.8314986274 12594235 11421492 10774834 11461765 12392966 11834606 19164858 18071297 10663392 17906064 18713872 16227642 11739529 10915739 11743745 12705907 14550746 19739265 19420014 17522070 11529661 16081117 15619225 11287661 12540782 16781746 12153990 12958197 16393943 16485898 19923254 19370779 2444490 16177239 15968718 16109766 19416960 17562736 19085960 14725611
MESH:D056486 Drug-Induced Liver Injury Amiodarone 11.8315265979 18218290
MESH:D056486 Drug-Induced Liver Injury Selenium 11.8315131321
MESH:D056486 Drug-Induced Liver Injury Thioacetamide 11.8312963478
MESH:D056486 Drug-Induced Liver Injury Valproic Acid 11.8319641884 1733752
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.0419426721
MESH:D004381 Duodenal Ulcer Omeprazole 4.2617151854 21218061 15991576 16613094
MESH:D050171 Dyslipidemias Clofibrate 4.0216707586
MESH:D004421 Dystonia Phenobarbital 10.221851702
MESH:D004421 Dystonia Valproic Acid 10.221851702
MESH:C538011 Eales disease Vitamin E 4.659068938
MESH:D004487 Edema pirinixic acid 2.4212083418
MESH:D004489 Edema, Cardiac Tretinoin 4.4118230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 3.1212538720
MESH:D016889 Endometrial Neoplasms Tretinoin 3.0616569247
MESH:D004831 Epilepsies, Myoclonic Phenobarbital 10.583659116
MESH:D004831 Epilepsies, Myoclonic Valproic Acid 10.583659116 17275665
MESH:D004828 Epilepsies, Partial Phenobarbital 9.7911558140 3922381
MESH:D004828 Epilepsies, Partial Valproic Acid 9.7916628512 3922381
MESH:D004827 Epilepsy Phenobarbital 6.5520417680
MESH:D004827 Epilepsy Valproic Acid 6.5518234410 20417680
MESH:D004832 Epilepsy, Absence Phenobarbital 8.676401628
MESH:D004832 Epilepsy, Absence Valproic Acid 8.676254150 7562514 6426943
MESH:D017029 Epilepsy, Complex Partial Phenobarbital 11.097750514
MESH:D017029 Epilepsy, Complex Partial Valproic Acid 11.097750514
MESH:D004830 Epilepsy, Tonic-Clonic Phenobarbital 10.283659116
MESH:D004830 Epilepsy, Tonic-Clonic Valproic Acid 10.283659116
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 1.9916530937
MESH:D005124 Eye Abnormalities Tretinoin 3.539664655 16938888
MESH:D005218 Fat Necrosis Thioacetamide 5.6616456712
MESH:D005234 Fatty Liver Amiodarone 29.9514986274
MESH:D005234 Fatty Liver arsenite 29.9518296743
MESH:D005234 Fatty Liver Clofibrate 29.9519224547
MESH:D005234 Fatty Liver Ethinyl Estradiol 29.9515345470
MESH:D005234 Fatty Liver pirinixic acid 29.9519236843 20131406
MESH:D005234 Fatty Liver Valproic Acid 29.9514986274 19224547
MESH:D005315 Fetal Diseases Valproic Acid 4.8316575769
MESH:D005317 Fetal Growth Retardation Valproic Acid 4.0718558336 8888407
MESH:D005355 Fibrosis arsenite 8.8218296743
MESH:D005355 Fibrosis Tretinoin 8.8217994277
MESH:D005756 Gastritis Acetaminophen 3.6216983495
MESH:D005909 Glioblastoma Tretinoin 2.9617312396
MESH:D006258 Head and Neck Neoplasms Tretinoin 3.1416096774
MESH:D006317 Hearing Loss, Noise-Induced Tretinoin 5.1016084493
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 10.9820471113
MESH:D006330 Heart Defects, Congenital Tretinoin 10.9814991402 9664655
MESH:D006330 Heart Defects, Congenital Vitamin E 10.9816080930
MESH:D006333 Heart Failure pirinixic acid 6.8120558911
MESH:D006333 Heart Failure Selenium 6.8117162251
MESH:D006501 Hepatic Encephalopathy Thioacetamide 4.5118665440 17276928 15929193
MESH:D006505 Hepatitis Thioacetamide 4.1516456712
MESH:D006529 Hepatomegaly Amiodarone 14.1315265979
MESH:D006529 Hepatomegaly Phenobarbital 14.1316109766
MESH:D006529 Hepatomegaly pirinixic acid 14.1318467677 16221962 19176532 19772884
MESH:D006548 Hernia, Diaphragmatic Vitamin E 2.6816490937 16863852
MESH:D019584 Hot Flashes Vitamin E 3.9214716179
MESH:D006849 Hydrocephalus Valproic Acid 4.8117688650
MESH:D006930 Hyperalgesia Acetaminophen 7.4416870215
MESH:D006930 Hyperalgesia Tretinoin 7.4416870215
MESH:D006937 Hypercholesterolemia Amiodarone 3.818137927 9751232
MESH:D017681 Hypereosinophilic Syndrome Tretinoin 4.5016778211
MESH:D006943 Hyperglycemia pirinixic acid 3.1220558911
MESH:D007021 Hypospadias Ethinyl Estradiol 3.7516945680 16569931
MESH:D007037 Hypothyroidism Amiodarone 11.4017991464 18020914
MESH:D007037 Hypothyroidism Propylthiouracil 11.4018031379 8137927
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.4012013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 2.4417937319
MESH:D007251 Influenza, Human Selenium 10.7716624496
MESH:D007251 Influenza, Human Vitamin E 10.7716624496
MESH:D007333 Insulin Resistance pirinixic acid 2.5916306350
MESH:D007410 Intestinal Diseases Tretinoin 3.7017994277
MESH:D007569 Jaw Abnormalities Tretinoin 3.8417551590 15992940
MESH:D007674 Kidney Diseases Acetaminophen 5.8415629191 12587719
MESH:D007674 Kidney Diseases Vitamin E 5.8412488133
MESH:D007676 Kidney Failure, Chronic Selenium 3.8216518626
MESH:D016773 Leishmaniasis, Cutaneous Omeprazole 4.0419248655
MESH:D007938 Leukemia Tretinoin 2.7417143497
MESH:D007951 Leukemia, Myeloid Tretinoin 3.6416482212 19285840 16932348
MESH:D015470 Leukemia, Myeloid, Acute Tretinoin 3.8419850784 16294345 17596541
MESH:D015470 Leukemia, Myeloid, Acute Valproic Acid 3.8416294345 17596541
MESH:D015473 Leukemia, Promyelocytic, Acute Tretinoin 3.1117217047 16823087 17368321 19075265 19225113 17649720 15748426 16891316 16935935 17107899 12679006 9834237 17506722 16788101 16331271 17361223 19029980 17294898 17301526 19035177 16766008 19642359 16140955 17712046 17339181
MESH:D017880 Limb Deformities, Congenital Tretinoin 3.269224671
MESH:D008064 Lipidoses Amiodarone 3.4615342952 17567588
MESH:D008103 Liver Cirrhosis arsenite 6.7418296743
MESH:D008103 Liver Cirrhosis Phenobarbital 6.7421047994
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 4.9215474484
MESH:D008106 Liver Cirrhosis, Experimental Thioacetamide 4.9217355460 15288473 18031379 16097051 16126171 15465738 11682029 18606216 15474484 12557150 18380797 12085344 15158331 10677585 15716488 16098781 17292413 12679928 15095483 18263696 16343077 15075984 18458672 15362042 16248980 12175628 15288472 11481614 15078482 16511523 11172339 18615449 15316131 18416461 17629604 18395095 18032466 17127702 18295389 14739098 15334695 12531686 16489207 12891558 17050028
MESH:D008106 Liver Cirrhosis, Experimental Tretinoin 4.9216248980 18397230
MESH:D008106 Liver Cirrhosis, Experimental Vitamin E 4.9216169303
MESH:D008107 Liver Diseases Acetaminophen 6.4719014921 16610002 19784758 12587719 12969438 11587558 19460945 16611625
MESH:D008107 Liver Diseases Phenobarbital 6.4719363144
MESH:D008107 Liver Diseases Thioacetamide 6.4718374380 15158337 16337175
MESH:D017114 Liver Failure, Acute Acetaminophen 9.4417185352 16871587
MESH:D017114 Liver Failure, Acute Thioacetamide 9.4415633222 15313186 17276928 12479984
MESH:D008113 Liver Neoplasms Aflatoxin B1 10.499163691 15890375 2125692 18177683
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 10.4921137059 20195826
MESH:D008113 Liver Neoplasms Phenobarbital 10.4919812893 19482888 8742319 15975961 19073162 21047994
MESH:D008113 Liver Neoplasms pirinixic acid 10.4920007298 16377806 15890375
MESH:D008114 Liver Neoplasms, Experimental Aflatoxin B1 5.898603461
MESH:D008114 Liver Neoplasms, Experimental Phenobarbital 5.8918308698 1399818 2563599 17172636 6150874
MESH:D008133 Long QT Syndrome Amiodarone 3.5315350150 17391786 11989578
MESH:D008171 Lung Diseases Amiodarone 7.3712587719
MESH:D008171 Lung Diseases Vitamin E 7.3716863852
MESH:D017563 Lung Diseases, Interstitial Amiodarone 11.0818516814
MESH:D017563 Lung Diseases, Interstitial Valproic Acid 11.0817228818
MESH:D008175 Lung Neoplasms Aflatoxin B1 4.8214755239
MESH:D008175 Lung Neoplasms arsenite 4.8216809336
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 4.8217053015 18520028 20464547 6695378 18816296 20135361 18569708 20064080 20869020
MESH:D008175 Lung Neoplasms Vitamin E 4.8211062179
MESH:D008325 Mammary Neoplasms, Experimental Selenium 2.7215318939
MESH:D008527 Medulloblastoma Tretinoin 2.7617453147
MESH:D008545 Melanoma Tretinoin 1.9316752155
MESH:D008546 Melanoma, Experimental Acetaminophen 3.5019513568
MESH:D008591 Meningomyelocele Tretinoin 4.3616940565
MESH:D008654 Mesothelioma Selenium 2.7715107826
MESH:D008881 Migraine Disorders Valproic Acid 3.1418803445 18765137
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 3.1416381670
MESH:D009135 Muscular Diseases pirinixic acid 3.4416239165
MESH:D009139 Musculoskeletal Abnormalities Valproic Acid 3.968888407
MESH:D009181 Mycoses Amiodarone 4.8512754197 17974566
MESH:D009190 Myelodysplastic Syndromes Tretinoin 7.2717596541
MESH:D009190 Myelodysplastic Syndromes Valproic Acid 7.2717596541
MESH:D009203 Myocardial Infarction pirinixic acid 2.1119151258
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 2.8916411023
MESH:D020191 Myoclonic Epilepsies, Progressive Phenobarbital 4.4117484760
MESH:D009369 Neoplasms Benzo(a)pyrene 8.0011141357
MESH:D009369 Neoplasms pirinixic acid 8.0017405874
MESH:D009369 Neoplasms Tretinoin 8.0016946489 16594593
MESH:D009389 Neovascularization, Pathologic arsenite 4.3515738583
MESH:D009421 Nervous System Malformations Tretinoin 3.719125849
MESH:D009436 Neural Tube Defects Tretinoin 7.169142499
MESH:D009436 Neural Tube Defects Valproic Acid 7.1616359493 8888407
MESH:D019636 Neurodegenerative Diseases Acetaminophen 2.8118514411
MESH:D052556 Niemann-Pick Disease, Type C Clofibrate 4.879802331
MESH:D009765 Obesity pirinixic acid 1.8020558911
MESH:D010018 Osteomalacia Phenobarbital 4.3017016548
MESH:D010051 Ovarian Neoplasms Tretinoin 2.3316936753
MESH:D010146 Pain Acetaminophen 6.4016870215
MESH:D010146 Pain Tretinoin 6.4016870215
MESH:D010190 Pancreatic Neoplasms Phenobarbital 5.2016965848
MESH:D010190 Pancreatic Neoplasms Tretinoin 5.2015976015
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.6211578682
MESH:D010954 Plasmacytoma Selenium 4.8315087411
MESH:D011230 Precancerous Conditions Phenobarbital 3.562563599
MESH:D011297 Prenatal Exposure Delayed Effects Valproic Acid 3.7720603192
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 3.2117292933
MESH:D011471 Prostatic Neoplasms Vitamin E 3.2115084515
MESH:D011507 Proteinuria Tretinoin 3.5416636307
MESH:D011537 Pruritus Ethinyl Estradiol 3.2515861022 16919318
MESH:D019310 Pseudolymphoma Phenobarbital 12.0012752131
MESH:D019310 Pseudolymphoma Valproic Acid 12.0012752131 11422049
MESH:D011625 Pterygium Tretinoin 4.7316723453
MESH:D011658 Pulmonary Fibrosis Amiodarone 2.8312490602 12832656 11597910
MESH:D015427 Reperfusion Injury pirinixic acid 2.3519058328
MESH:D012208 Rhabdomyosarcoma Tretinoin 10.6516116481 16283617
MESH:D012208 Rhabdomyosarcoma Valproic Acid 10.6519155313
MESH:D012468 Salivary Gland Neoplasms marker/mechanism 16762588
MESH:D012559 Schizophrenia Valproic Acid 2.0615737665 19110320
MESH:D012640 Seizures Phenobarbital 5.853137016 4039156 16876388 11442880
MESH:D012640 Seizures Valproic Acid 5.851511512 16876388 11044598 17978042 3137016 14763951 11738929 15475178
MESH:D003294 Seizures, Febrile Phenobarbital 4.766407741
OMIM:609620 SHORT QT SYNDROME 1 Amiodarone 5.0218724381
MESH:D012871 Skin Diseases Vitamin E 2.4218709164
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 5.5819755658 10029692
MESH:D012878 Skin Neoplasms Tretinoin 5.5816467112
MESH:D013088 Spermatocele Ethinyl Estradiol 3.8916709447
MESH:D016135 Spinal Dysraphism Valproic Acid 3.7319490988
MESH:D013226 Status Epilepticus Valproic Acid 4.4912833885
MESH:D013272 Stomach Diseases Omeprazole 4.5518545984
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 2.332093021 20155912
MESH:D013274 Stomach Neoplasms Tretinoin 2.3317261132
MESH:D013276 Stomach Ulcer Amiodarone 7.3718087811
MESH:D013276 Stomach Ulcer Omeprazole 7.3715991576 18237397 17977527 16755016 11906479 10750652
MESH:D020521 Stroke Vitamin E 3.4716517955
MESH:D013610 Tachycardia Amiodarone 4.2211238279
MESH:D017180 Tachycardia, Ventricular Amiodarone 4.1319225199
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.5611994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.0915669648
MESH:D013959 Thyroid Diseases Amiodarone 4.7019731979
MESH:D013964 Thyroid Neoplasms Phenobarbital 11.771399818
MESH:D013964 Thyroid Neoplasms Propylthiouracil 11.7715710170
MESH:D013964 Thyroid Neoplasms Tretinoin 11.7716026305 17045167
MESH:D013971 Thyrotoxicosis Amiodarone 4.8018020914 19584973
MESH:D014062 Tongue Neoplasms Tretinoin 3.7316051514
MESH:D016171 Torsades de Pointes Amiodarone 4.1317467628 11989578
MESH:D014178 Translocation, Genetic Valproic Acid 5.1817262798
MESH:D014376 Tuberculosis Tretinoin 3.1916040207
MESH:D020194 Unverricht-Lundborg Syndrome Valproic Acid 4.463119515
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 2.1517053015
MESH:D014564 Urogenital Abnormalities Valproic Acid 4.588888407
MESH:D014581 Urticaria Acetaminophen 2.9110982225
MESH:D002583 Uterine Cervical Neoplasms Tretinoin 3.6216129372
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 3.2314692618
MESH:D014604 Uveal Neoplasms Tretinoin 4.5516752155
MESH:D014689 Venous Insufficiency coumarin 5.7212708602
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.4815869587 14671159
MESH:D014820 Vitiligo Tretinoin 3.9916761959
MESH:D009396 Wilms Tumor Tretinoin 3.9116287080
Pathway ID Pathway Name
KEGG:00562 Inositol phosphate metabolism
KEGG:01100 Metabolic pathways
Pharmacogenomics Knowledge Base Top
Drug Bank Top
Drugbank ID Action Drug Name Description
DB01840 - 2-Deoxy-D-Glucitol 6-(E)-Vinylhomophosphonate
DB01907 - Nicotinamide-Adenine-Dinucleotide
DB02212 - Pyrophosphate 2-
DB04077 - Glycerol Solvents;Cryoprotective Agents
DB04516 - 2-Deoxy-Glucitol-6-Phosphate
No data
No data
No data

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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