AutismKB 2.0

Annotation Detail for C20orf111


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Basic Information Top
Gene Symbol:C20orf111 ( HSPC207,Perit1,dJ1183I21.1 )
Gene Full Name: chromosome 20 open reading frame 111
Band: 20q13.11
Quick LinksEntrez ID:51526; OMIM: NA; Uniprot ID:CT111_HUMAN; ENSEMBL ID: ENSG00000132823; HGNC ID:
Relate to Another Database: SFARIGene; denovo-db
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Chemical ID Chemical Name Interaction Interaction Action Publication
D017638 Asbestos, Crocidolite Asbestos, Crocidolite results in increased expression of C20ORF111 mRNAincreases expression 18687144
D001564 Benzo(a)pyrene Benzo(a)pyrene results in increased expression of C20ORF111 mRNAincreases expression 20064835
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased expression of C20ORF111 mRNAincreases expression 19150397
D020122 tert-Butylhydroperoxide tert-Butylhydroperoxide results in decreased expression of C20ORF111 mRNAdecreases expression 15336504
D016572 Cyclosporine Cyclosporine results in increased expression of C20ORF111 mRNAincreases expression 20106945
C106014 gedunin gedunin results in increased expression of C20ORF111 mRNAincreases expression 17010675
C050414 tripterine tripterine results in increased expression of C20ORF111 mRNAincreases expression 17010675
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 2.0420464547 20127859
MESH:D000236 Adenoma Benzo(a)pyrene 2.806695378
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 4.4319183758
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 2.0020146248 17474063
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 2.1120419170
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7.1720889678
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 7.1712371664
MESH:D002779 Cholestasis Cyclosporine 3.1219486331
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 4.5420426865
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 4.5416530937
MESH:D005234 Fatty Liver Cyclosporine 3.1419224547
MESH:D005355 Fibrosis Cyclosporine 3.5012639820 12168785
MESH:D005885 Gingival Hyperplasia Cyclosporine 4.628708960
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 2.7820471113
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.8215720958
MESH:D006973 Hypertension Cyclosporine 2.1810903974
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.8815604871
MESH:D007674 Kidney Diseases Cyclosporine 2.4818776723 10903974 8314463
MESH:D007680 Kidney Neoplasms Cyclosporine 2.9712371664
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 2.1220195826 21137059
MESH:D055370 Lung Injury Asbestos, Crocidolite 4.3817365036
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 1.5720464547 18520028 18816296 20064080 18569708 20869020 6695378 17053015 20135361
MESH:D008654 Mesothelioma Asbestos, Crocidolite 3.2716166281 16966607 18303189
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 5.2316801185
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 3.4016381670
MESH:D009369 Neoplasms Benzo(a)pyrene 2.2811141357
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.8817954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.5319348381 18481113
MESH:D010995 Pleural Diseases Asbestos, Crocidolite 5.2510923243
MESH:D011230 Precancerous Conditions Cyclosporine 3.4712371664
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 2.9317292933
MESH:D011565 Psoriasis Cyclosporine 2.3016882103
MESH:D011658 Pulmonary Fibrosis Asbestos, Crocidolite 3.1117365031 17975199 17322281 15814490
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 6.0919755658 10029692
MESH:D012878 Skin Neoplasms tert-Butylhydroperoxide 6.098532709
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 1.562093021 20155912
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 2.2617053015
MESH:D014605 Uveitis Cyclosporine 4.431336536
MESH:D014985 Xerophthalmia Cyclosporine 4.8817120751
No data
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018