Annotation Detail for VPS54
Basic Information
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| Gene Symbol: | VPS54 ( HCC8,SLP-8p,VPS54L,hVps54L ) |
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| Gene Full Name: | vacuolar protein sorting 54 homolog (S. cerevisiae) |
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| Band: | 2p15-p14 |
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| Quick Links | Entrez ID:51542; OMIM: NA; Uniprot ID:VPS54_HUMAN; ENSEMBL ID: ENSG00000143952; HGNC ID: 18652 |
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| Relate to Another Database: |
SFARIGene;
denovo-db |
| Chemical ID |
Chemical Name |
Interaction |
Interaction Action |
Publication |
|---|
| D000082 |
Acetaminophen |
Acetaminophen affects the expression of VPS54 mRNA | affects expression | 17562736
|
| C014949 |
acetylhydrazine |
acetylhydrazine results in decreased expression of VPS54 mRNA | decreases expression | 15282401
|
| D000643 |
Ammonium Chloride |
Ammonium Chloride affects the expression of VPS54 mRNA | affects expression | 16483693
|
| D015123 |
7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide |
7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of VPS54 mRNA | decreases expression | 19150397
|
| D011374 |
Progesterone |
Progesterone inhibits the reaction [VPS54 gene mutant form results in decreased activity of CHAT protein] | decreases activity|decreases reaction | 17052708
|
| D011374 |
Progesterone |
Progesterone inhibits the reaction [VPS54 gene mutant form results in decreased expression of BDNF mRNA] | decreases expression|decreases reaction | 17052708
|
| D011374 |
Progesterone |
Progesterone inhibits the reaction [VPS54 gene mutant form results in decreased expression of CHAT protein] | decreases expression|decreases reaction | 17052708
|
| Disease ID |
Disease Name |
Direct Evidence |
Inference Chemical Name |
Inference Score |
Publication |
|---|
| MESH:D000138 |
Acidosis |
|
Ammonium Chloride |
4.10 | 18287403 |
| MESH:D000799 |
Angioedema |
|
Acetaminophen |
4.45 | 10982225 |
| MESH:D001321 |
Autistic Disorder |
|
Acetaminophen |
1.40 | 18445737 |
| MESH:D020201 |
Brain Hemorrhage, Traumatic |
|
Progesterone |
5.95 | 17868700 |
| MESH:D001930 |
Brain Injuries |
|
Progesterone |
4.74 | 15665606 15845082 15380490 |
| MESH:D001943 |
Breast Neoplasms |
|
Progesterone |
2.41 | 17614352 16175315 15562024 |
| MESH:D006528 |
Carcinoma, Hepatocellular |
|
Acetaminophen |
1.40 | 3084413 |
| MESH:D002386 |
Cataract |
|
Acetaminophen |
2.77 | 10977129 |
| MESH:D002471 |
Cell Transformation, Neoplastic |
|
7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide |
2.96 | 20889678 |
| MESH:D003929 |
Diabetic Neuropathies |
|
Progesterone |
4.98 | 17187935 |
| MESH:D056486 |
Drug-Induced Liver Injury |
|
Acetaminophen |
1.66 | 14550746 11421492 18713872 12705907 17906064 16485898 18071297 17562736 11743745 12958197 12153990 16109766 11287661 10774834 10663392 19164858 12540782 12392966 10915739 16177239 11739529 19420014 11529661 11461765 19085960 15968718 19370779 19416960 2444490 15619225 16227642 11834606 16781746 14725611 17522070 16393943 19923254 16081117 14986274 12594235 19739265 |
| MESH:D056487 |
Drug-Induced Liver Injury, Chronic |
|
Acetaminophen |
4.71 | 19426721 |
| MESH:D004681 |
Encephalomyelitis, Autoimmune, Experimental |
|
Progesterone |
4.22 | 17692515 |
| MESH:D004715 |
Endometriosis |
|
Progesterone |
4.11 | 16134523 |
| MESH:D004938 |
Esophageal Neoplasms |
|
7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide |
2.14 | 20426865 |
| MESH:D005756 |
Gastritis |
|
Acetaminophen |
4.29 | 16983495 |
| MESH:D006930 |
Hyperalgesia |
|
Acetaminophen |
2.99 | 16870215 |
| MESH:D020244 |
Infarction, Middle Cerebral Artery |
|
Progesterone |
4.89 | 15869954 |
| MESH:D007249 |
Inflammation |
|
Progesterone |
2.75 | 15869954 |
| MESH:D007674 |
Kidney Diseases |
|
Acetaminophen |
2.38 | 15629191 12587719 |
| MESH:D008107 |
Liver Diseases |
|
Acetaminophen |
1.69 | 19784758 16611625 12587719 19014921 16610002 12969438 11587558 19460945 |
| MESH:D017114 |
Liver Failure, Acute |
|
Acetaminophen |
3.58 | 16871587 17185352 |
| MESH:D008325 |
Mammary Neoplasms, Experimental |
|
Progesterone |
3.07 | 17203775 11408345 |
| MESH:D008546 |
Melanoma, Experimental |
|
Acetaminophen |
4.05 | 19513568 |
| MESH:D019636 |
Neurodegenerative Diseases |
|
Acetaminophen |
3.18 | 18514411 |
| MESH:D010051 |
Ovarian Neoplasms |
|
Progesterone |
2.61 | 17393432 16525653 |
| MESH:D010146 |
Pain |
|
Acetaminophen |
2.69 | 16870215 |
| MESH:D012468 |
Salivary Gland Neoplasms |
|
Progesterone |
2.95 | 18045962 |
| MESH:D013119 |
Spinal Cord Injuries |
|
Progesterone |
4.82 | 16503802 15862959 |
| MESH:D014581 |
Urticaria |
|
Acetaminophen |
3.38 | 10982225 |
Related Pathway Information