AutismKB 2.0

Annotation Detail for PDGFRB


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Basic Information Top
Gene Symbol:PDGFRB ( CD140B,JTK12,PDGFR,PDGFR1 )
Gene Full Name: platelet-derived growth factor receptor, beta polypeptide
Band: 5q32
Quick LinksEntrez ID:5159; OMIM: 173410; Uniprot ID:PGFRB_HUMAN; ENSEMBL ID: ENSG00000113721; HGNC ID: 8804
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa04010MAPK signaling pathway
hsa04020Calcium signaling pathway
hsa04540Gap junction
hsa04810Regulation of actin cytoskeleton
hsa05218Melanoma
hsa05214Glioma
hsa05215Prostate cancer
hsa04510Focal adhesion
hsa04060Cytokine-cytokine receptor interaction
hsa05200Pathways in cancer
Pathway IDPathway Name
Signaling by PDGF
Pathway IDPathway Name
200035S1P3 pathway
200033Signaling events mediated by PTP1B
200171Validated targets of C-MYC transcriptional repression
200127PDGFR-beta signaling pathway
200065Signaling events mediated by TCPTP
200071S1P1 pathway
200053Nectin adhesion pathway
Pathway IDPathway Name
P00005Angiogenesis
No data
Related Diseases/Disorders Top
Desease IDDesease Name
Cancers
H00042Glioma
Cancers of the nervous system
No data
No data
No data
Desease Name
Myelomonocytic leukemia, chronic
Myeloproliferative disorder with eosinophilia
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C054919 2,2-(2-chlorophenyl-4'-chlorophenyl)-1,1-dichloroethene [Dichlorodiphenyldichloroethane co-treated with Dichlorodiphenyl Dichloroethylene co-treated with 2,2-(2-chlorophenyl-4'-chlorophenyl)-1,1-dichloroethene co-treated with Aldrin co-treated with Dieldrin] results in increased expression of PDGFRB mRNAaffects cotreatment|increases expression 19422813
C117011 3-(4-dimethylamino-benzylidenyl)-2-indolinone 3-(4-dimethylamino-benzylidenyl)-2-indolinone results in decreased activity of PDGFRB proteindecreases activity 15728459
C027576 4-hydroxy-2-nonenal 4-hydroxy-2-nonenal binds to PDGFRB proteinaffects binding 16527993
C027576 4-hydroxy-2-nonenal 4-hydroxy-2-nonenal inhibits the reaction [PDGF protein results in increased phosphorylation of PDGFRB protein]decreases reaction|increases phosphorylation 16527993
C027576 4-hydroxy-2-nonenal dinitrophenylhydrazine inhibits the reaction [4-hydroxy-2-nonenal binds to PDGFRB protein]affects binding|decreases reaction 16527993
C027576 4-hydroxy-2-nonenal Hydralazine inhibits the reaction [4-hydroxy-2-nonenal binds to PDGFRB protein]affects binding|decreases reaction 16527993
C027576 4-hydroxy-2-nonenal 4-hydroxy-2-nonenal affects the activity of PDGFRB proteinaffects activity 17263919
C106250 6,7-dimethoxy-3-phenylquinoxaline 6,7-dimethoxy-3-phenylquinoxaline inhibits the reaction [Leukotriene D4 results in increased phosphorylation of and results in increased activity of PDGFRB protein]decreases reaction|increases activity|increases phosphorylation 12223454
D000082 Acetaminophen Acetaminophen affects the expression of PDGFRB mRNAaffects expression 17562736
D000171 Acrolein Acrolein binds to PDGFRB proteinaffects binding 16527993
D000452 Aldrin [Dichlorodiphenyldichloroethane co-treated with Dichlorodiphenyl Dichloroethylene co-treated with 2,2-(2-chlorophenyl-4'-chlorophenyl)-1,1-dichloroethene co-treated with Aldrin co-treated with Dieldrin] results in increased expression of PDGFRB mRNAaffects cotreatment|increases expression 19422813
D000643 Ammonium Chloride Ammonium Chloride affects the expression of PDGFRB mRNAaffects expression 16483693
C432165 anthra(1,9-cd)pyrazol-6(2H)-one anthra(1,9-cd)pyrazol-6(2H)-one results in decreased expression of PDGFRB mRNAdecreases expression 18332871
C432165 anthra(1,9-cd)pyrazol-6(2H)-one anthra(1,9-cd)pyrazol-6(2H)-one results in decreased expression of PDGFRB proteindecreases expression 18332871
C070515 bisindolylmaleimide I bisindolylmaleimide I inhibits the reaction [Leukotriene D4 results in increased phosphorylation of and results in increased activity of PDGFRB protein]decreases reaction|increases activity|increases phosphorylation 12223454
C006780 bisphenol A bisphenol A results in increased expression of PDGFRB mRNAincreases expression 12604637
C006780 bisphenol A bisphenol A results in increased expression of PDGFRB proteinincreases expression 12604637
C055494 caffeic acid phenethyl ester [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in increased expression of PDGFRB mRNAaffects cotreatment|increases expression 20360939
D002251 Carbon Tetrachloride Carbon Tetrachloride results in increased expression of PDGFRB mRNAincreases expression 17962354
D002251 Carbon Tetrachloride F2R protein affects the reaction [Carbon Tetrachloride results in increased expression of PDGFRB mRNA]affects reaction|increases expression 17962354
D002251 Carbon Tetrachloride PPARD protein affects the reaction [Carbon Tetrachloride results in increased expression of PDGFRB mRNA]affects reaction|increases expression 18038451
D002251 Carbon Tetrachloride Carbon Tetrachloride results in decreased expression of PDGFRB proteindecreases expression 17069927
D002251 Carbon Tetrachloride Carbon Tetrachloride results in increased expression of PDGFRB mRNAincreases expression 15623374
18006644
D002251 Carbon Tetrachloride Curcumin inhibits the reaction [Carbon Tetrachloride results in increased expression of PDGFRB mRNA]decreases reaction|increases expression 18006644
D002713 Chlorine [Ozone co-treated with Chlorine] affects the expression of PDGFRB mRNAaffects cotreatment|affects expression 18636392
D003375 Coumestrol Coumestrol results in increased expression of PDGFRB mRNAincreases expression 12604637
D003375 Coumestrol Coumestrol results in increased expression of PDGFRB proteinincreases expression 12604637
C497448 CP-673,451 CP-673,451 inhibits the reaction [PDGFB protein results in increased phosphorylation of PDGFRB protein]decreases reaction|increases phosphorylation 15705896
C497448 CP-673,451 CP-673,451 results in decreased activity of PDGFRB proteindecreases activity 15705896
C497448 CP-673,451 CP-673,451 results in decreased phosphorylation of PDGFRB proteindecreases phosphorylation 15705896
C461979 CT52923 CT52923 binds to and results in decreased activity of PDGFRB proteinaffects binding|decreases activity 15994924
C007164 cumene hydroperoxide cumene hydroperoxide inhibits the reaction [PDGF protein results in increased phosphorylation of PDGFRB protein]decreases reaction|increases phosphorylation 16527993
D003474 Curcumin Curcumin inhibits the reaction [Carbon Tetrachloride results in increased expression of PDGFRB mRNA]decreases reaction|increases expression 18006644
D003474 Curcumin Curcumin results in decreased expression of PDGFRB mRNAdecreases expression 18332871
D003474 Curcumin Curcumin results in decreased expression of PDGFRB proteindecreases expression 18332871
D003474 Curcumin Curcumin results in decreased phosphorylation of PDGFRB proteindecreases phosphorylation 18332871
17372590
D016572 Cyclosporine Cyclosporine results in increased expression of PDGFRB mRNAincreases expression 20106945
D003545 Cysteine Cysteine inhibits the reaction [PDGFB protein results in increased phosphorylation of PDGFRB protein]decreases reaction|increases phosphorylation 15158331
D003545 Cysteine Cysteine inhibits the reaction [Thioacetamide results in increased expression of PDGFRB protein]decreases reaction|increases expression 15158331
D003545 Cysteine Cysteine results in decreased expression of PDGFRB proteindecreases expression 15158331
D003676 Deferoxamine Deferoxamine results in decreased expression of PDGFRB proteindecreases expression 18032466
D003907 Dexamethasone [Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in decreased expression of PDGFRB mRNAaffects cotreatment|decreases expression 16054899
D003907 Dexamethasone EGF protein inhibits the reaction [[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in decreased expression of PDGFRB mRNA]affects cotreatment|decreases expression|decreases reaction 16054899
D003907 Dexamethasone Tetrachlorodibenzodioxin inhibits the reaction [[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in decreased expression of PDGFRB mRNA]affects cotreatment|decreases expression|decreases reaction 16054899
D003632 Dichlorodiphenyldichloroethane [Dichlorodiphenyldichloroethane co-treated with Dichlorodiphenyl Dichloroethylene co-treated with 2,2-(2-chlorophenyl-4'-chlorophenyl)-1,1-dichloroethene co-treated with Aldrin co-treated with Dieldrin] results in increased expression of PDGFRB mRNAaffects cotreatment|increases expression 19422813
D003633 Dichlorodiphenyl Dichloroethylene [Dichlorodiphenyldichloroethane co-treated with Dichlorodiphenyl Dichloroethylene co-treated with 2,2-(2-chlorophenyl-4'-chlorophenyl)-1,1-dichloroethene co-treated with Aldrin co-treated with Dieldrin] results in increased expression of PDGFRB mRNAaffects cotreatment|increases expression 19422813
D004026 Dieldrin [Dichlorodiphenyldichloroethane co-treated with Dichlorodiphenyl Dichloroethylene co-treated with 2,2-(2-chlorophenyl-4'-chlorophenyl)-1,1-dichloroethene co-treated with Aldrin co-treated with Dieldrin] results in increased expression of PDGFRB mRNAaffects cotreatment|increases expression 19422813
D004052 Diethylnitrosamine [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in increased expression of PDGFRB mRNAaffects cotreatment|increases expression 20360939
D004052 Diethylnitrosamine Diethylnitrosamine results in increased expression of PDGFRB mRNAincreases expression 19638242
D004054 Diethylstilbestrol Diethylstilbestrol results in increased expression of PDGFRB mRNAincreases expression 12604637
D004054 Diethylstilbestrol Diethylstilbestrol results in increased expression of PDGFRB proteinincreases expression 12604637
C446799 dinitrophenylhydrazine dinitrophenylhydrazine inhibits the reaction [4-hydroxy-2-nonenal binds to PDGFRB protein]affects binding|decreases reaction 16527993
D004642 Emodin Emodin inhibits the reaction [PDGFB protein results in increased phosphorylation of PDGFRB protein]decreases reaction|increases phosphorylation 15288473
D004642 Emodin Emodin results in decreased expression of PDGFRB proteindecreases expression 15288473
D004997 Ethinyl Estradiol [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of PDGFRB mRNAaffects cotreatment|increases expression 17942748
D004997 Ethinyl Estradiol Ethinyl Estradiol results in decreased expression of PDGFRB mRNAdecreases expression 17557909
D005665 Furosemide Furosemide results in increased expression of PDGFRB mRNAincreases expression 16526316
D019833 Genistein Genistein results in increased expression of PDGFRB mRNAincreases expression 12604637
D019833 Genistein Genistein results in increased expression of PDGFRB proteinincreases expression 12604637
D006830 Hydralazine Hydralazine inhibits the reaction [4-hydroxy-2-nonenal binds to PDGFRB protein]affects binding|decreases reaction 16527993
D016627 Oxidopamine Oxidopamine results in decreased expression of PDGFRB mRNAdecreases expression 15518916
C097613 imatinib imatinib results in decreased expression of PDGFRB proteindecreases expression 15786421
C097613 imatinib imatinib results in decreased phosphorylation of PDGFRB proteindecreases phosphorylation 15786421
C097613 imatinib imatinib results in decreased phosphorylation of PDGFRB proteindecreases phosphorylation 15867366
C097613 imatinib imatinib results in decreased activity of PDGFRB proteindecreases activity 17377918
C078038 inchinko-to inchinko-to inhibits the reaction [PDGFB protein results in increased phosphorylation of PDGFRB protein]decreases reaction|increases phosphorylation 15288473
C078038 inchinko-to inchinko-to inhibits the reaction [Thioacetamide results in increased expression of PDGFRB protein]decreases reaction|increases expression 15288473
D007213 Indomethacin Indomethacin results in increased expression of PDGFRB mRNAincreases expression 17440234
D019266 Iron, Dietary Iron, Dietary affects the reaction [Thioacetamide affects the expression of PDGFRB mRNA]affects expression|affects reaction 18032466
D015056 1-Methyl-3-isobutylxanthine [Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in decreased expression of PDGFRB mRNAaffects cotreatment|decreases expression 16054899
D015056 1-Methyl-3-isobutylxanthine EGF protein inhibits the reaction [[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in decreased expression of PDGFRB mRNA]affects cotreatment|decreases expression|decreases reaction 16054899
D015056 1-Methyl-3-isobutylxanthine Tetrachlorodibenzodioxin inhibits the reaction [[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in decreased expression of PDGFRB mRNA]affects cotreatment|decreases expression|decreases reaction 16054899
D008070 Lipopolysaccharides Lipopolysaccharides results in decreased expression of PDGFRB mRNAdecreases expression 12057914
C040527 lipoxin A4 lipoxin A4 affects the reaction [PDGFB protein results in increased phosphorylation of PDGFRB protein]affects reaction|increases phosphorylation 12223454
C040527 lipoxin A4 lipoxin A4 inhibits the reaction [Leukotriene D4 results in increased activity of PDGFRB protein]decreases reaction|increases activity 12223454
D019808 Losartan Losartan inhibits the reaction [AGT protein results in increased expression of PDGFRB mRNA]decreases reaction|increases expression 17043664
D017998 Leukotriene D4 6,7-dimethoxy-3-phenylquinoxaline inhibits the reaction [Leukotriene D4 results in increased phosphorylation of and results in increased activity of PDGFRB protein]decreases reaction|increases activity|increases phosphorylation 12223454
D017998 Leukotriene D4 bisindolylmaleimide I inhibits the reaction [Leukotriene D4 results in increased phosphorylation of and results in increased activity of PDGFRB protein]decreases reaction|increases activity|increases phosphorylation 12223454
D017998 Leukotriene D4 Leukotriene D4 promotes the reaction [SRC protein binds to PDGFRB protein]affects binding|increases reaction 12223454
D017998 Leukotriene D4 Leukotriene D4 results in increased phosphorylation of and results in increased activity of PDGFRB proteinincreases activity|increases phosphorylation 12223454
D017998 Leukotriene D4 lipoxin A4 inhibits the reaction [Leukotriene D4 results in increased activity of PDGFRB protein]decreases reaction|increases activity 12223454
D017998 Leukotriene D4 pobilukast inhibits the reaction [Leukotriene D4 results in increased phosphorylation of and results in increased activity of PDGFRB protein]decreases reaction|increases activity|increases phosphorylation 12223454
D008715 Methionine Methionine inhibits the reaction [PDGFB protein results in increased phosphorylation of PDGFRB protein]decreases reaction|increases phosphorylation 15158331
D008715 Methionine Methionine inhibits the reaction [Thioacetamide results in increased expression of PDGFRB protein]decreases reaction|increases expression 15158331
D008715 Methionine Methionine results in decreased expression of PDGFRB proteindecreases expression 15158331
D009151 Mustard Gas IL10 protein affects the reaction [Mustard Gas affects the expression of PDGFRB mRNA]affects expression|affects reaction 16173061
C025256 nonylphenol nonylphenol results in decreased expression of PDGFRB mRNAdecreases expression 15518916
D010126 Ozone [Ozone co-treated with Chlorine] affects the expression of PDGFRB mRNAaffects cotreatment|affects expression 18636392
C093973 PD 98059 PD 98059 results in decreased expression of PDGFRB mRNAdecreases expression 18332871
C093973 PD 98059 PD 98059 results in decreased expression of PDGFRB proteindecreases expression 18332871
D010795 Phthalic Acids Phthalic Acids results in decreased expression of PDGFRB mRNAdecreases expression 15518916
C006253 pirinixic acid pirinixic acid results in decreased expression of PDGFRB mRNAdecreases expression 18445702
C006253 pirinixic acid pirinixic acid results in increased expression of PDGFRB mRNAincreases expression 17426115
C052393 pobilukast pobilukast inhibits the reaction [Leukotriene D4 results in increased phosphorylation of and results in increased activity of PDGFRB protein]decreases reaction|increases activity|increases phosphorylation 12223454
C025299 polyphenols polyphenols results in decreased expression of PDGFRB mRNAdecreases expression 16293270
D020849 Raloxifene Raloxifene affects the expression of PDGFRB mRNAaffects expression 14699072
C059514 resveratrol resveratrol inhibits the reaction [PDGFB protein results in increased phosphorylation of PDGFRB protein]decreases reaction|increases phosphorylation 16343977
C089730 rosiglitazone [Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in decreased expression of PDGFRB mRNAaffects cotreatment|decreases expression 16054899
C089730 rosiglitazone EGF protein inhibits the reaction [[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in decreased expression of PDGFRB mRNA]affects cotreatment|decreases expression|decreases reaction 16054899
C089730 rosiglitazone Tetrachlorodibenzodioxin inhibits the reaction [[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in decreased expression of PDGFRB mRNA]affects cotreatment|decreases expression|decreases reaction 16054899
C010327 salinomycin salinomycin results in decreased expression of PDGFRB mRNAdecreases expression 19682730
C017947 sodium arsenite sodium arsenite results in decreased expression of PDGFRB mRNAdecreases expression 16014739
C412603 SU 6668 SU 6668 results in decreased phosphorylation of and results in decreased activity of PDGFRB proteindecreases activity|decreases phosphorylation 16144927
C412603 SU 6668 SU 6668 results in decreased activity of PDGFRB proteindecreases activity 15551349
15739567
14760097
16132614
15788688
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of PDGFRB mRNAdecreases expression 20106945
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of PDGFRB mRNAaffects cotreatment|increases expression 17942748
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin inhibits the reaction [[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in decreased expression of PDGFRB mRNA]affects cotreatment|decreases expression|decreases reaction 16054899
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of PDGFRB mRNAdecreases expression 18691609
D013853 Thioacetamide Cysteine inhibits the reaction [Thioacetamide results in increased expression of PDGFRB protein]decreases reaction|increases expression 15158331
D013853 Thioacetamide inchinko-to inhibits the reaction [Thioacetamide results in increased expression of PDGFRB protein]decreases reaction|increases expression 15288473
D013853 Thioacetamide Iron, Dietary affects the reaction [Thioacetamide affects the expression of PDGFRB mRNA]affects expression|affects reaction 18032466
D013853 Thioacetamide Methionine inhibits the reaction [Thioacetamide results in increased expression of PDGFRB protein]decreases reaction|increases expression 15158331
D013853 Thioacetamide Thioacetamide results in increased expression of PDGFRB proteinincreases expression 15288473
15158331
D014212 Tretinoin Tretinoin results in increased expression of PDGFRB mRNA alternative formincreases expression 17303670
D002762 Cholecalciferol Cholecalciferol results in increased expression of PDGFRB mRNAincreases expression 17170073
D014810 Vitamin E Vitamin E results in increased expression of PDGFRB mRNAincreases expression 19244175
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 2.2215322242 14514962 11752688
MESH:D000015 Abnormalities, Multiple imatinib 4.6718322153
MESH:D000022 Abortion, Spontaneous imatinib 5.5518322153
MESH:D000138 Acidosis Ammonium Chloride 2.9118287403
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.2817505938
MESH:D058186 Acute Kidney Injury resveratrol 3.2816538975
MESH:D055371 Acute Lung Injury Acrolein 16.9221297076 20525806
MESH:D055371 Acute Lung Injury Chlorine 16.9220601635
MESH:D055371 Acute Lung Injury Lipopolysaccharides 16.9211850527 18653653
MESH:D055371 Acute Lung Injury pirinixic acid 16.9218653653
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 5.8914692618
MESH:D000230 Adenocarcinoma Genistein 5.8911473722
MESH:D000230 Adenocarcinoma Indomethacin 5.8916537180
MESH:D000236 Adenoma Diethylnitrosamine 8.9110737359 6695378
MESH:D000236 Adenoma Indomethacin 8.9111497255
MESH:D000236 Adenoma resveratrol 8.9115688382
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 13.5419052882 17162532 17620307 18056438 19061943 16434500
MESH:D018248 Adenoma, Liver Cell pirinixic acid 13.5416434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 13.5416835633
MESH:D000310 Adrenal Gland Neoplasms sodium arsenite 4.0415276417
MESH:D018246 Adrenocortical Adenoma sodium arsenite 4.2416712894 17306315
MESH:D000382 Agricultural Workers' Diseases Dichlorodiphenyl Dichloroethylene 4.1716487989
MESH:D000419 Albuminuria Losartan 9.8812586211
MESH:D000419 Albuminuria Raloxifene 9.8817451421 17308373
MESH:D019973 Alcohol-Related Disorders Curcumin 4.4217887948
MESH:D000505 Alopecia Tretinoin 3.0915955085
MESH:D016301 Alveolar Bone Loss Indomethacin 4.7117225004
MESH:D000544 Alzheimer Disease Acrolein 16.2917570602 15207723 14715435
MESH:D000544 Alzheimer Disease Curcumin 16.2915590663
MESH:D000544 Alzheimer Disease Indomethacin 16.2915579461 17627676
MESH:D000544 Alzheimer Disease Ozone 16.2915513908
MESH:D000544 Alzheimer Disease Raloxifene 16.2915800139
MESH:D000544 Alzheimer Disease resveratrol 16.2916162502 16183991
MESH:D000544 Alzheimer Disease rosiglitazone 16.2919621015
MESH:D000686 Amyloidosis Diethylstilbestrol 3.8615469931
MESH:D000690 Amyotrophic Lateral Sclerosis 4-hydroxy-2-nonenal 3.6710965797
MESH:D000740 Anemia Tetrachlorodibenzodioxin 2.3811748828
MESH:D000799 Angioedema Acetaminophen 3.1810982225
MESH:D001014 Aortic Aneurysm Indomethacin 4.2310231640
MESH:D017544 Aortic Aneurysm, Abdominal Indomethacin 4.2410388637
MESH:D001161 Arteriosclerosis Acrolein 8.2215014928
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 8.2211256880
MESH:D018771 Arthralgia Indomethacin 4.512160914
MESH:D001169 Arthritis, Experimental Dexamethasone 13.9917659584
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 13.9915885639
MESH:D001169 Arthritis, Experimental resveratrol 13.9917115116
MESH:D001169 Arthritis, Experimental Tretinoin 13.9916412693
MESH:D001172 Arthritis, Rheumatoid Curcumin 8.8816807698
MESH:D001172 Arthritis, Rheumatoid Indomethacin 8.8811248219
MESH:D001172 Arthritis, Rheumatoid Ozone 8.8815570426
MESH:D001172 Arthritis, Rheumatoid Tretinoin 8.8816292516
MESH:D001249 Asthma Leukotriene D4 9.298222486 9690572
MESH:D001249 Asthma Mustard Gas 9.2910378619
MESH:D001249 Asthma Ozone 9.2917854713 16373670
MESH:D001249 Asthma Tretinoin 9.2916456186
MESH:D050197 Atherosclerosis Acrolein 12.3416037261 16126721 17363696
MESH:D050197 Atherosclerosis Curcumin 12.3418704882
MESH:D050197 Atherosclerosis Losartan 12.3410821809
MESH:D050197 Atherosclerosis resveratrol 12.3417967414 16873680
MESH:D001289 Attention Deficit Disorder with Hyperactivity Oxidopamine 7.3814699433
MESH:D001289 Attention Deficit Disorder with Hyperactivity Phthalic Acids 7.3820106747
MESH:D001321 Autistic Disorder Acetaminophen 2.4118445737
MESH:D001321 Autistic Disorder Cysteine 2.4116917939 19056591 19267885
MESH:D001321 Autistic Disorder Methionine 2.4119267885 16917939 19056591
MESH:D001327 Autoimmune Diseases Cholecalciferol 8.9916142846
MESH:D001327 Autoimmune Diseases Curcumin 8.9919761891
MESH:D001471 Barrett Esophagus Tretinoin 3.7816935849
MESH:D001477 Bartter Syndrome Indomethacin 4.3510684365
MESH:D001768 Blister Mustard Gas 4.5119167455
MESH:D001778 Blood Coagulation Disorders pirinixic acid 17.1919483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 17.1912125929
MESH:D001778 Blood Coagulation Disorders Thioacetamide 17.1919483382
MESH:D001778 Blood Coagulation Disorders Tretinoin 17.1916206674 16197459
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.1315340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.3215746008
MESH:D001859 Bone Neoplasms imatinib 4.7215867366
MESH:D001862 Bone Resorption bisphenol A 3.2811985600
MESH:D001929 Brain Edema Indomethacin 4.3611481608
MESH:D001930 Brain Injuries Raloxifene 3.8416580743
MESH:D002545 Brain Ischemia Curcumin 13.3716770732
MESH:D002545 Brain Ischemia Indomethacin 13.3712524144
MESH:D002545 Brain Ischemia resveratrol 13.3717600658
MESH:D001932 Brain Neoplasms Curcumin 7.8717596214
MESH:D001932 Brain Neoplasms SU 6668 7.8715739567
MESH:D001943 Breast Neoplasms bisphenol A 12.5217123778
MESH:D001943 Breast Neoplasms Curcumin 12.5219250217 18462866 18593918 16243823
MESH:D001943 Breast Neoplasms Deferoxamine 12.5215993339
MESH:D001943 Breast Neoplasms Dichlorodiphenyl Dichloroethylene 12.5215061365
MESH:D001943 Breast Neoplasms Dieldrin 12.5215770527 11859874
MESH:D001943 Breast Neoplasms Diethylnitrosamine 12.5217474063
MESH:D001943 Breast Neoplasms Diethylstilbestrol 12.5217129689 15324884
MESH:D001943 Breast Neoplasms Genistein 12.5216873071 16541309 17200150
MESH:D001943 Breast Neoplasms imatinib 12.5217614352
MESH:D001943 Breast Neoplasms Indomethacin 12.5217401462
MESH:D001943 Breast Neoplasms Raloxifene 12.5217261762 15758505 16837676 15572757 17595753 17049068 16912660 17893378 17242785 15775269 17952589 17440819
MESH:D001943 Breast Neoplasms resveratrol 12.5217651959 17534123 16393696
MESH:D001943 Breast Neoplasms salinomycin 12.5219682730
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 12.5220435547
MESH:D001943 Breast Neoplasms Tretinoin 12.5216873071 16166294 16443354
MESH:D016535 Bronchial Hyperreactivity Leukotriene D4 7.4712794006 12654629
MESH:D016535 Bronchial Hyperreactivity Ozone 7.4715516495 14754758 19059883 17626835 18315731 16777450 18417511
MESH:D001989 Bronchiolitis Obliterans Mustard Gas 4.5115286001
MESH:D029481 Bronchitis, Chronic Mustard Gas 4.3217687719 10378619
MESH:D001997 Bronchopulmonary Dysplasia Tretinoin 3.9416813970
MESH:D002056 Burns Indomethacin 4.0710459503
MESH:D002100 Cachexia Indomethacin 10.2415625704 11239499 16537180 15141370
MESH:D002100 Cachexia Ozone 10.2416183385
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 7.8415700767 3786805 18705752 16097048 15721981 16050911 15673190 16124888 16227642 10355542 16011737 16192424
MESH:D002252 Carbon Tetrachloride Poisoning Vitamin E 7.8416050911
MESH:D002277 Carcinoma Curcumin 6.5418593918
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 6.5416835633
MESH:D018236 Carcinoma, Embryonal Tretinoin 4.5016168501
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 22.463084413
MESH:D006528 Carcinoma, Hepatocellular anthra(1,9-cd)pyrazol-6(2H)-one 22.4619418558
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 22.4618788625
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 22.4617428255 18393292 19701751 16328049 18506893 18788625 16807293 19919837 17978847 18210153 18785209 19107877 10737359 17138121 3581430 20512989 11831363 16830150 19394651 19208518 19335982 16540662 21159647 16698587 18978308 20214788 18056438 10672840 19519916 17761372 16779866 3084413 19822196 17173139 20084675 17162532 20524982 16878318 18971187 17055752 16681979 16569478 18691550 16502159 19539802 16288022 19418558 18494052 18665156 20514400 19171122 20727157 20432363 16935385 20007298 20101231 20935162 19383236 19052882
MESH:D006528 Carcinoma, Hepatocellular Diethylstilbestrol 22.4615948411 16924424
MESH:D006528 Carcinoma, Hepatocellular Genistein 22.4616924424
MESH:D006528 Carcinoma, Hepatocellular Indomethacin 22.4616391822
MESH:D006528 Carcinoma, Hepatocellular resveratrol 22.4619321006 16227395
MESH:D006528 Carcinoma, Hepatocellular sodium arsenite 22.4615276417 17306315 16507464
MESH:D006528 Carcinoma, Hepatocellular Thioacetamide 22.4617997003
MESH:D006528 Carcinoma, Hepatocellular Tretinoin 22.461917145
MESH:D002278 Carcinoma in Situ bisphenol A 4.3417123778
MESH:D018827 Carcinoma, Lewis Lung Indomethacin 9.2711053908
MESH:D018827 Carcinoma, Lewis Lung resveratrol 9.2716675471
MESH:D018276 Carcinoma, Medullary Indomethacin 4.7014736730 18791128 11352223
MESH:D002289 Carcinoma, Non-Small-Cell Lung Curcumin 2.7218414057
MESH:D002292 Carcinoma, Renal Cell Indomethacin 3.0317341418
MESH:D002294 Carcinoma, Squamous Cell Curcumin 11.7418462866
MESH:D002294 Carcinoma, Squamous Cell Indomethacin 11.7412636206 15482327
MESH:D002294 Carcinoma, Squamous Cell resveratrol 11.7416227395
MESH:D002294 Carcinoma, Squamous Cell sodium arsenite 11.7418572023
MESH:D002294 Carcinoma, Squamous Cell Tretinoin 11.7416096774 16051514
MESH:D002295 Carcinoma, Transitional Cell Raloxifene 3.5117572228
MESH:D006332 Cardiomegaly Losartan 5.9412586211 15969258
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 5.9416120746 18670907 18850075
MESH:D002318 Cardiovascular Diseases Genistein 9.5216332659
MESH:D002318 Cardiovascular Diseases Raloxifene 9.5215775269
MESH:D002318 Cardiovascular Diseases resveratrol 9.5215458977
MESH:D002386 Cataract Acetaminophen 5.8410977129
MESH:D002386 Cataract Tretinoin 5.8417460283
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 8.4612371664
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 8.4617174075 2727394 21159647 7505956
MESH:D002471 Cell Transformation, Neoplastic sodium arsenite 8.4620056578 19524636
MESH:D018290 Cervical Intraepithelial Neoplasia Tretinoin 3.9416129372
MESH:D002659 Child Development Disorders, Pervasive Methionine 4.0419267885
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 12.9219052882
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 12.9216835633
MESH:D018281 Cholangiocarcinoma Thioacetamide 12.9218291259
MESH:D002764 Cholecystitis Indomethacin 4.5111181007
MESH:D002779 Cholestasis Cyclosporine 10.4619486331
MESH:D002779 Cholestasis Ethinyl Estradiol 10.4616919318 17333356 17681005 17110522 15861022 11677210 16105132
MESH:D002779 Cholestasis pirinixic acid 10.4619176532
MESH:D002822 Choriocarcinoma Tretinoin 4.5016461808
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 4.7016354765 8697196 12621046 15340226 15668235
MESH:D002972 Cleft Palate Tretinoin 4.709407595
MESH:D003072 Cognition Disorders Raloxifene 3.9815800139
MESH:D003092 Colitis Curcumin 12.4516782535 16804969 18200517
MESH:D003092 Colitis resveratrol 12.4516474422
MESH:D003092 Colitis Tretinoin 12.4517035595
MESH:D003103 Coloboma Curcumin 3.9618809619
MESH:D003110 Colonic Neoplasms Curcumin 11.8419359593 16340194
MESH:D003110 Colonic Neoplasms Dexamethasone 11.8415824018
MESH:D003110 Colonic Neoplasms Genistein 11.8417182828
MESH:D003110 Colonic Neoplasms Indomethacin 11.8415963497 15786552 11260862 15625704 15637740 15936596
MESH:D003110 Colonic Neoplasms polyphenols 11.8416293270
MESH:D003110 Colonic Neoplasms resveratrol 11.8416338953
MESH:D015179 Colorectal Neoplasms Acrolein 3.2117597105
MESH:D015179 Colorectal Neoplasms Indomethacin 3.2118059344 12606626 17054584 11197048
MESH:D015179 Colorectal Neoplasms resveratrol 3.2116550006
MESH:D000013 Congenital Abnormalities Dichlorodiphenyldichloroethane 7.9715095906
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 7.9717141729 14669216
MESH:D016510 Corneal Neovascularization Curcumin 4.2618497527
MESH:D003327 Coronary Disease resveratrol 3.3116507316
MESH:D018352 Coronavirus Infections Indomethacin 5.0517302372
MESH:D019465 Craniofacial Abnormalities Dexamethasone 6.2217728286
MESH:D019465 Craniofacial Abnormalities imatinib 6.2218322153
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 6.2220055451 10048152 15322242
MESH:D019465 Craniofacial Abnormalities Tretinoin 6.229142499 17551590 8800419 10589399 9125849 9664655 9224671 16925845 9211117 14991402
MESH:D019465 Craniofacial Abnormalities Vitamin E 6.2219769572
MESH:D003456 Cryptorchidism Diethylstilbestrol 3.9412952375 16002989
MESH:D003556 Cystitis Acrolein 4.7312161096
MESH:D003865 Depressive Disorder, Major Raloxifene 3.6117474826
MESH:D017449 Dermatitis, Allergic Contact Dexamethasone 2.8212438553
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.0818249437
MESH:D003920 Diabetes Mellitus rosiglitazone 3.7517446233
MESH:D003921 Diabetes Mellitus, Experimental resveratrol 3.2416873680
MESH:D003924 Diabetes Mellitus, Type 2 Curcumin 11.3518403477
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 11.3520387270
MESH:D003924 Diabetes Mellitus, Type 2 Genistein 11.3516647724
MESH:D003924 Diabetes Mellitus, Type 2 rosiglitazone 11.3512642470
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 11.3517107852
MESH:D003928 Diabetic Nephropathies Curcumin 11.9718204486
MESH:D003928 Diabetic Nephropathies Raloxifene 11.9715920148 17451421 17308373
MESH:D003928 Diabetic Nephropathies resveratrol 11.9716286809
MESH:D003967 Diarrhea Dexamethasone 6.257237001
MESH:D003967 Diarrhea Indomethacin 6.257907874 7237001
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 12.0319923254 12540782 19416960 17906064 17522070 11743745 14725611 12153990 16781746 11739529 16081117 12705907 11834606 14550746 16109766 10774834 12594235 16393943 16227642 11529661 10915739 18713872 15619225 17562736 11461765 19370779 19739265 12392966 11287661 10663392 19085960 19420014 15968718 18071297 12958197 16485898 19164858 2444490 14986274 16177239 11421492
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 12.037120509 15968718 15998439 21278145 16177239 2869522 19085960 16227642 3732212 6884620 7440962 10092053 15027814 17522070 11566570 10915739 7179309 4309450 6623471 9327722 3786805 19336974
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 12.0319107877
MESH:D056486 Drug-Induced Liver Injury polyphenols 12.0319370779
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 12.0320420201
MESH:D056486 Drug-Induced Liver Injury Thioacetamide 12.0312963478
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 3.4419426721
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.2711462148
MESH:D004374 Ductus Arteriosus, Patent Indomethacin 4.5018446180 17190690 16326151 12774134 16133044 18043480
MESH:D004381 Duodenal Ulcer Curcumin 7.3817351913
MESH:D004381 Duodenal Ulcer Indomethacin 7.3817202747 17351913 17045617 17329845 10671773 11595415 11991626 17151854 16699067 11535926 11595431
MESH:D004417 Dyspnea Chlorine 13.6520016425
MESH:D004417 Dyspnea Dichlorodiphenyl Dichloroethylene 13.6516487989
MESH:D004417 Dyspnea Furosemide 13.6516935035
MESH:C538011 Eales disease Vitamin E 4.049068938
MESH:D004485 Eczema Dexamethasone 3.8412438553
MESH:D004487 Edema bisindolylmaleimide I 42.128273558
MESH:D004487 Edema Dexamethasone 42.1219703484
MESH:D004487 Edema Furosemide 42.1211834646
MESH:D004487 Edema imatinib 42.1219703484
MESH:D004487 Edema Indomethacin 42.127907874 8985016 16100529 19703484 8273558 10653021 7990266
MESH:D004487 Edema Mustard Gas 42.1211428647 11428631 11402378 9260866
MESH:D004487 Edema pirinixic acid 42.1212083418
MESH:D004487 Edema Raloxifene 42.1215860553
MESH:D004487 Edema resveratrol 42.128985016
MESH:D004487 Edema rosiglitazone 42.1212083418
MESH:D004487 Edema Tetrachlorodibenzodioxin 42.1212711302 11000095
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 9.7516714409 15322242 18230668
MESH:D004489 Edema, Cardiac Tretinoin 9.7518230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 11.8612538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Raloxifene 11.8615845917
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental resveratrol 11.8617872969
MESH:D004714 Endometrial Hyperplasia Diethylstilbestrol 9.7416402032
MESH:D004714 Endometrial Hyperplasia Genistein 9.7416402032
MESH:D016889 Endometrial Neoplasms Diethylstilbestrol 9.9116804899 15700306
MESH:D016889 Endometrial Neoplasms Genistein 9.9111473722
MESH:D016889 Endometrial Neoplasms Tretinoin 9.9116569247
MESH:D004715 Endometriosis Indomethacin 7.1815652904
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 7.1810568697 9294722
MESH:D019446 Endotoxemia Indomethacin 8.5018509659
MESH:D019446 Endotoxemia Lipopolysaccharides 8.5015821434 15328337 17637181
MESH:D004751 Enteritis Indomethacin 4.0917763956 10567023 16328016
MESH:D020345 Enterocolitis, Necrotizing Indomethacin 10.2717980183
MESH:D020345 Enterocolitis, Necrotizing resveratrol 10.2717923197
MESH:D004802 Eosinophilia Indomethacin 3.4311298111
MESH:D004890 Erythema Mustard Gas 4.519357497
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 4.4516302075
MESH:D004938 Esophageal Neoplasms Indomethacin 2.6211005569
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 7.1711564622
MESH:D005124 Eye Abnormalities Tretinoin 7.1716938888 9664655
MESH:D005218 Fat Necrosis Thioacetamide 5.0616456712
MESH:D005234 Fatty Liver Carbon Tetrachloride 33.1461145 16239168 15959796 16045604 19224547 17595544 12795759 12631006
MESH:D005234 Fatty Liver Curcumin 33.1419297423
MESH:D005234 Fatty Liver Cyclosporine 33.1419224547
MESH:D005234 Fatty Liver Diethylnitrosamine 33.1421071580 20387270
MESH:D005234 Fatty Liver Ethinyl Estradiol 33.1415345470
MESH:D005234 Fatty Liver pirinixic acid 33.1420131406 19236843
MESH:D005234 Fatty Liver Raloxifene 33.1417473493
MESH:D005234 Fatty Liver rosiglitazone 33.1419196556
MESH:D052776 Female Urogenital Diseases Diethylstilbestrol 3.2316611131 16534752 16002989 16513791 15751030
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 2.8211858732
MESH:D005334 Fever Indomethacin 7.4717627676 11852909 10431976
MESH:D005334 Fever Lipopolysaccharides 7.479205823 11852909
MESH:D018222 Fibromatosis, Aggressive imatinib 5.0017453242
MESH:D005354 Fibrosarcoma Indomethacin 4.2510962813
MESH:D005355 Fibrosis Carbon Tetrachloride 31.8618705752
MESH:D005355 Fibrosis Curcumin 31.8618705752
MESH:D005355 Fibrosis Cyclosporine 31.8612639820 12168785
MESH:D005355 Fibrosis Emodin 31.8619474275
MESH:D005355 Fibrosis Indomethacin 31.8617994277
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 31.8620067830
MESH:D005355 Fibrosis Tretinoin 31.8617994277
MESH:D005499 Folliculitis Indomethacin 4.5111298111
MESH:D005739 Gas Poisoning Chlorine 4.3520016425
MESH:D005756 Gastritis Acetaminophen 8.9516983495
MESH:D005756 Gastritis Indomethacin 8.9515046732
MESH:D005770 Gastrointestinal Neoplasms Curcumin 4.0618462866
MESH:D005833 Genital Neoplasms, Female Diethylstilbestrol 10.6616452187
MESH:D005833 Genital Neoplasms, Female sodium arsenite 10.6616452187
MESH:D005885 Gingival Hyperplasia Cyclosporine 3.578708960
MESH:D005909 Glioblastoma Curcumin 13.2817596214
MESH:D005909 Glioblastoma Genistein 13.2816598420
MESH:D005909 Glioblastoma Indomethacin 13.2812870263
MESH:D005909 Glioblastoma Tretinoin 13.2817312396
MESH:D005910 Glioma Indomethacin 6.0716487511 18371953
MESH:D005910 Glioma SU 6668 6.0715739567
MESH:D005923 Glomerulosclerosis, Focal Segmental Indomethacin 3.7611849393
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 3.9310696789
MESH:D006073 Gout Indomethacin 4.7011248219
MESH:D006258 Head and Neck Neoplasms Curcumin 10.3618462866 18829502
MESH:D006258 Head and Neck Neoplasms Indomethacin 10.3615482327
MESH:D006258 Head and Neck Neoplasms Tretinoin 10.3616096774
MESH:D034381 Hearing Loss Furosemide 4.2717868369
MESH:D006317 Hearing Loss, Noise-Induced Tretinoin 4.5016084493
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 8.9011294989 10048152
MESH:D006330 Heart Defects, Congenital Tretinoin 8.9014991402 9664655
MESH:D006330 Heart Defects, Congenital Vitamin E 8.9016080930
MESH:D006331 Heart Diseases Raloxifene 3.0711110106
MESH:D006333 Heart Failure Furosemide 9.6016845234 16011733 12660669
MESH:D006333 Heart Failure Losartan 9.6010979640
MESH:D006333 Heart Failure pirinixic acid 9.6020558911
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 3.7715720958
MESH:D006463 Hemolytic-Uremic Syndrome Lipopolysaccharides 3.8116366002
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 2.7511000095
MESH:D006501 Hepatic Encephalopathy Indomethacin 8.9915633222
MESH:D006501 Hepatic Encephalopathy Thioacetamide 8.9918665440 17276928 15929193
MESH:D006505 Hepatitis Carbon Tetrachloride 12.3719110552 19900420
MESH:D006505 Hepatitis Dichlorodiphenyl Dichloroethylene 12.3716487989
MESH:D006505 Hepatitis Thioacetamide 12.3716456712
MESH:D019698 Hepatitis C, Chronic Indomethacin 4.0615135802
MESH:D006529 Hepatomegaly pirinixic acid 6.1818467677 16221962 19772884 19176532
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 6.1815340226 16120746 12621046
MESH:D015417 Hereditary Sensory and Motor Neuropathy Curcumin 4.4017701891
MESH:D006548 Hernia, Diaphragmatic Dexamethasone 5.057520565
MESH:D006548 Hernia, Diaphragmatic Vitamin E 5.0516490937 16863852
MESH:D006561 Herpes Simplex resveratrol 3.5416876885
MESH:D006689 Hodgkin Disease sodium arsenite 2.6212676792
MESH:D019584 Hot Flashes Vitamin E 3.3214716179
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.3816354765 8697196 16959395 18606429 15340226
MESH:D006930 Hyperalgesia Acetaminophen 14.4116870215
MESH:D006930 Hyperalgesia Indomethacin 14.4112727271
MESH:D006930 Hyperalgesia rosiglitazone 14.4112083418
MESH:D006930 Hyperalgesia Tretinoin 14.4116870215
MESH:D034321 Hyperamylasemia Indomethacin 5.0517883296
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 3.8816899240
MESH:D006934 Hypercalcemia Furosemide 4.4917652376
MESH:D053565 Hypercalciuria Furosemide 5.0017652376
MESH:D006937 Hypercholesterolemia Curcumin 7.4518704882
MESH:D006937 Hypercholesterolemia resveratrol 7.4517188708
MESH:D006940 Hyperemia Indomethacin 4.3612524144
MESH:D017681 Hypereosinophilic Syndrome Tretinoin 3.9316778211
MESH:D006943 Hyperglycemia pirinixic acid 2.6220558911
MESH:D006949 Hyperlipidemias Indomethacin 7.5017546600
MESH:D006949 Hyperlipidemias resveratrol 7.5016873680
MESH:D006962 Hyperparathyroidism, Secondary Furosemide 5.2115086907
MESH:D006965 Hyperplasia Diethylstilbestrol 3.8012960047 14722030
MESH:D006973 Hypertension Cyclosporine 13.2310903974
MESH:D006973 Hypertension Dexamethasone 13.2317042910
MESH:D006973 Hypertension Losartan 13.2312512695 14597852 12586211 10090350 15969258
MESH:D006973 Hypertension Raloxifene 13.2317577099 15787275
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 13.2318850075 18670907
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 3.4515338365
MESH:D046110 Hypertension, Pregnancy-Induced Furosemide 9.7016612254
MESH:D046110 Hypertension, Pregnancy-Induced Hydralazine 9.7016612254
MESH:D017379 Hypertrophy, Left Ventricular resveratrol 3.7317488730
MESH:C537153 Hypomagnesemia primary Furosemide 5.0011041285
MESH:D007019 Hypoproteinemia Furosemide 5.2116096441
MESH:D007021 Hypospadias Diethylstilbestrol 9.1416002989
MESH:D007021 Hypospadias Ethinyl Estradiol 9.1416945680 16569931
MESH:D007022 Hypotension Furosemide 4.0211041285
MESH:D007024 Hypotension, Orthostatic Furosemide 4.7615811171
MESH:D007077 Ileal Diseases 1-Methyl-3-isobutylxanthine 10.5218306037
MESH:D007077 Ileal Diseases Indomethacin 10.5210574470 18306037
MESH:D007079 Ileitis Indomethacin 4.7010647630 10651667 16133968
MESH:D007235 Infant, Premature, Diseases Indomethacin 4.7116133044
MESH:D020244 Infarction, Middle Cerebral Artery resveratrol 4.0117600658
MESH:D007246 Infertility Diethylstilbestrol 3.7415036965
MESH:D007247 Infertility, Female 2,2-(2-chlorophenyl-4'-chlorophenyl)-1,1-dichloroethene 13.9412515675
MESH:D007247 Infertility, Female Dieldrin 13.9410630421
MESH:D007247 Infertility, Female Ethinyl Estradiol 13.9412013081
MESH:D007248 Infertility, Male 2,2-(2-chlorophenyl-4'-chlorophenyl)-1,1-dichloroethene 16.3412515675
MESH:D007248 Infertility, Male Coumestrol 16.3416892005
MESH:D007248 Infertility, Male Dichlorodiphenyl Dichloroethylene 16.3417192596 12948891
MESH:D007248 Infertility, Male Ethinyl Estradiol 16.3417937319
MESH:D007248 Infertility, Male sodium arsenite 16.3412646999 15346721
MESH:D007249 Inflammation bisindolylmaleimide I 37.398273558
MESH:D007249 Inflammation Curcumin 37.3918403477 16956363 17151092
MESH:D007249 Inflammation Dexamethasone 37.3911099482 8960868
MESH:D007249 Inflammation Diethylnitrosamine 37.3918785209
MESH:D007249 Inflammation Indomethacin 37.393291741 7812673 12568917
MESH:D007249 Inflammation Lipopolysaccharides 37.3912878042 17255318 17237260 9205823 17963957
MESH:D007249 Inflammation Losartan 37.3912586211
MESH:D007249 Inflammation Mustard Gas 37.3916001271 8975870 11428647 17524151 9357497 11402378 11428631 9260866 11428620
MESH:D007249 Inflammation polyphenols 37.3916366677
MESH:D007249 Inflammation resveratrol 37.3916366677
MESH:D007249 Inflammation rosiglitazone 37.3912083418
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 37.3912200463 12878042
MESH:D015212 Inflammatory Bowel Diseases Curcumin 2.9118596194 18200517
MESH:D007251 Influenza, Human resveratrol 8.8916624496
MESH:D007251 Influenza, Human Vitamin E 8.8916624496
MESH:D007333 Insulin Resistance bisphenol A 9.8016393666
MESH:D007333 Insulin Resistance pirinixic acid 9.8016306350
MESH:D007333 Insulin Resistance rosiglitazone 9.8016306350
MESH:D007410 Intestinal Diseases Indomethacin 7.7910210152 15831440 15610444 11713966 17994277 11686837 18236018 17329856 11855677
MESH:D007410 Intestinal Diseases Tretinoin 7.7917994277
MESH:D007414 Intestinal Neoplasms caffeic acid phenethyl ester 8.2110783313
MESH:D007414 Intestinal Neoplasms Curcumin 8.2110783313
MESH:D019586 Intracranial Hypertension Indomethacin 4.7115241188
MESH:D019189 Iron Metabolism Disorders Lipopolysaccharides 4.0317255318
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 7.9916580747
MESH:D007569 Jaw Abnormalities Tretinoin 7.9915992940 17551590
MESH:D007579 Jejunal Diseases 1-Methyl-3-isobutylxanthine 10.5218306037
MESH:D007579 Jejunal Diseases Indomethacin 10.5210574470 18306037 16133968
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 3.7815604871
MESH:D007674 Kidney Diseases Acetaminophen 26.7512587719 15629191
MESH:D007674 Kidney Diseases Acrolein 26.7512488133
MESH:D007674 Kidney Diseases caffeic acid phenethyl ester 26.7515369732
MESH:D007674 Kidney Diseases Cyclosporine 26.7518776723 10903974 8314463
MESH:D007674 Kidney Diseases Furosemide 26.7511041285
MESH:D007674 Kidney Diseases Indomethacin 26.7517190690
MESH:D007674 Kidney Diseases sodium arsenite 26.7520008137
MESH:D007674 Kidney Diseases Vitamin E 26.7512488133
MESH:D007680 Kidney Neoplasms Cyclosporine 5.6912371664
MESH:D007680 Kidney Neoplasms Diethylstilbestrol 5.6916762066 15003126 14681315
MESH:D007859 Learning Disorders Diethylstilbestrol 3.4317184923
MESH:D007889 Leiomyoma Curcumin 9.1618555241
MESH:D007889 Leiomyoma Raloxifene 9.1616973256
MESH:D016773 Leishmaniasis, Cutaneous Indomethacin 3.3711703811 10320625 12228301
MESH:D007938 Leukemia Curcumin 8.4118462866
MESH:D007938 Leukemia Genistein 8.4118980019 17468513
MESH:D007938 Leukemia Tretinoin 8.4117143497
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell Curcumin 8.2716106398
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell Emodin 8.2717077332
MESH:D007948 Leukemia, Monocytic, Acute anthra(1,9-cd)pyrazol-6(2H)-one 9.9616972261
MESH:D007948 Leukemia, Monocytic, Acute PD 98059 9.9616972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive imatinib 7.3917301526 15748426 19208803 15107311
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive Indomethacin 7.3910785260 16572323 15631656
MESH:D007951 Leukemia, Myeloid imatinib 8.0317236224
MESH:D007951 Leukemia, Myeloid Tretinoin 8.0316482212 16932348 19285840
MESH:D015470 Leukemia, Myeloid, Acute 6,7-dimethoxy-3-phenylquinoxaline 7.5717050201
MESH:D015470 Leukemia, Myeloid, Acute Deferoxamine 7.5720368581
MESH:D015470 Leukemia, Myeloid, Acute Indomethacin 7.5718360721
MESH:D015470 Leukemia, Myeloid, Acute Tretinoin 7.5716294345 19850784 17596541
MESH:D015473 Leukemia, Promyelocytic, Acute caffeic acid phenethyl ester 10.2616766008
MESH:D015473 Leukemia, Promyelocytic, Acute resveratrol 10.2616087638
MESH:D015473 Leukemia, Promyelocytic, Acute Tretinoin 10.2619075265 16140955 17107899 15748426 16788101 17649720 17361223 16331271 16891316 17301526 17339181 12679006 17712046 19225113 19642359 17217047 9834237 16766008 19035177 16823087 17368321 16935935 17506722 19029980 17294898
MESH:D015458 Leukemia, T-Cell Curcumin 4.1416106398
MESH:D007964 Leukocytosis Indomethacin 4.7116537180
MESH:D007969 Leukomalacia, Periventricular Indomethacin 5.0517980183
MESH:D007970 Leukopenia Lipopolysaccharides 4.0515821434
MESH:D017880 Limb Deformities, Congenital Dichlorodiphenyl Dichloroethylene 7.0212745335
MESH:D017880 Limb Deformities, Congenital Tretinoin 7.029224671
MESH:D008101 Liver Abscess, Amebic Indomethacin 5.0511479899
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 5.2916239168 11408273 16221502 16943688 17334410 11903743 17174718 17157831 21278145
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 5.2918665156 19638242 20032147 18522880 18407596
MESH:D008106 Liver Cirrhosis, Experimental marker/mechanism 18466260 15623374
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 37.0912666154 18420326 18210741 17922224 18376398 12609069 12898905 17525996 17761835 13678700 18054572 15052691 10355542 17766677 16015684 15876570 18277467 18317297 17708605 18481824 15673190 17900296 14512876 18166357 14716496 15123356 15362042 17976157 17823541 16011737 15925388 17565644 17557913 16116963 12445418 18395095 15996030 12667390 16027843 16097048 12586293 16136751 15370692 15931870 12632514 16192424 12389079 12632512 18412020 17631135 18472094 12958196 18429990 15057751 12741479 17640975 12546737 14724832 18395914 12445421 17698563 15650968 18006644 18156304 18251166 15893842 12649538 15959796 15818738 17481882 15730626 16638106 18279442 16033810 17714472 18418968 17805973 20821823 17721639 17944888 16248980 18263696 18205269 14748882 15338365 14716833 14620537 11481614 18339082 18705752 18187930 17869086 18472332
MESH:D008106 Liver Cirrhosis, Experimental Curcumin 37.0917355460 18705752 18006644
MESH:D008106 Liver Cirrhosis, Experimental Cysteine 37.0915158331
MESH:D008106 Liver Cirrhosis, Experimental Dexamethasone 37.0916718785
MESH:D008106 Liver Cirrhosis, Experimental Emodin 37.0915288473
MESH:D008106 Liver Cirrhosis, Experimental Genistein 37.0917823541
MESH:D008106 Liver Cirrhosis, Experimental imatinib 37.0916596278
MESH:D008106 Liver Cirrhosis, Experimental inchinko-to 37.0915288473
MESH:D008106 Liver Cirrhosis, Experimental Indomethacin 37.0918194892
MESH:D008106 Liver Cirrhosis, Experimental Lipopolysaccharides 37.0912878042
MESH:D008106 Liver Cirrhosis, Experimental Losartan 37.0915573910 17900296 12445418
MESH:D008106 Liver Cirrhosis, Experimental Methionine 37.0915158331
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 37.0915474484
MESH:D008106 Liver Cirrhosis, Experimental rosiglitazone 37.0917347453 15980055
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 37.0912878042
MESH:D008106 Liver Cirrhosis, Experimental Thioacetamide 37.0916248980 16098781 18458672 18295389 16343077 11481614 15095483 15474484 11172339 15362042 18031379 12679928 16511523 11682029 17355460 14739098 15465738 17127702 15078482 12085344 18380797 18395095 17292413 12891558 16126171 17629604 15716488 12175628 15158331 15288473 15288472 15075984 18032466 10677585 16489207 12531686 15316131 18606216 18615449 17050028 12557150 15334695 18263696 18416461 16097051
MESH:D008106 Liver Cirrhosis, Experimental Tretinoin 37.0918397230 16248980
MESH:D008106 Liver Cirrhosis, Experimental Vitamin E 37.0916169303
MESH:D008107 Liver Diseases Acetaminophen 12.9616611625 11587558 19014921 12587719 19460945 16610002 12969438 19784758
MESH:D008107 Liver Diseases Carbon Tetrachloride 12.9616964402 16246199 17285989 15720792 15830285
MESH:D008107 Liver Diseases Curcumin 12.9616956363
MESH:D008107 Liver Diseases Diethylnitrosamine 12.9617034775
MESH:D008107 Liver Diseases polyphenols 12.9616698588
MESH:D008107 Liver Diseases Thioacetamide 12.9618374380 16337175 15158337
MESH:D017093 Liver Failure Carbon Tetrachloride 3.5315123358
MESH:D017114 Liver Failure, Acute Acetaminophen 12.9616871587 17185352
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 12.9616899240 14706259
MESH:D017114 Liver Failure, Acute Thioacetamide 12.9615633222 12479984 15313186 17276928
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 20.6819294768
MESH:D008113 Liver Neoplasms Dieldrin 20.688742319 9539021
MESH:D008113 Liver Neoplasms Diethylnitrosamine 20.6819427195 19254457 19833225 19850985 9163691 19996281 19690152 18648771 19073162 18644402 21071580 20137499 21167192 15885732 20501860 20434301 21047994 20101389 2422723 18977376 19642983 19812893 20405173 19294768 2862719 18754104 10737359 19255062 20492335 12771043 19499222 15175105 16942905 20452335 12112319 20583210 19551842 21278145 19426721 19090486 19638242 19256749 20118626 18978307
MESH:D008113 Liver Neoplasms Diethylstilbestrol 20.6815890375 16712894
MESH:D008113 Liver Neoplasms pirinixic acid 20.6820007298 16377806 15890375
MESH:D008113 Liver Neoplasms resveratrol 20.6819321006 19073162 19812893 20405173
MESH:D008113 Liver Neoplasms sodium arsenite 20.6815276417 16712894
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 20.6816984957
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 7.2812014681 15583823
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 7.2817174075 21159647 18308698 18079962 2563599 19539802 3124819 18282651 17942915 18775883 9362446 16267830 18253720 18544905 16842330 17854601 19126423 19009564 18164116 19004024 18093689 19519916
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 7.2812151625
MESH:D008171 Lung Diseases Acrolein 18.2111504702
MESH:D008171 Lung Diseases Mustard Gas 18.2118161513 18702808
MESH:D008171 Lung Diseases Ozone 18.218266340 19066396
MESH:D008171 Lung Diseases sodium arsenite 18.2119095001
MESH:D008171 Lung Diseases Vitamin E 18.2116863852
MESH:D055370 Lung Injury Lipopolysaccharides 7.1521114838
MESH:D055370 Lung Injury Ozone 7.1520417186
MESH:D008175 Lung Neoplasms Curcumin 13.0316243823 18462866 19359593
MESH:D008175 Lung Neoplasms Dexamethasone 13.0311195469 15824018
MESH:D008175 Lung Neoplasms Diethylnitrosamine 13.0321163286 20970405 20512841 6695378
MESH:D008175 Lung Neoplasms Indomethacin 13.0316537180 11497255 11053908
MESH:D008175 Lung Neoplasms Mustard Gas 13.033148597 8781369
MESH:D008175 Lung Neoplasms Ozone 13.037614698 8597069
MESH:D008175 Lung Neoplasms sodium arsenite 13.0319931552 16712894 17077188 17306315 15276417
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 13.0319555203 11884234
MESH:D008175 Lung Neoplasms Vitamin E 13.0311062179
MESH:D008181 Lupus Nephritis Diethylstilbestrol 4.5015166399
MESH:D008223 Lymphoma Curcumin 6.1918462866
MESH:D008223 Lymphoma Diethylstilbestrol 6.1915700306
MESH:D016393 Lymphoma, B-Cell resveratrol 3.7017088997
MESH:D008228 Lymphoma, Non-Hodgkin resveratrol 3.3414749477
MESH:D016399 Lymphoma, T-Cell Curcumin 4.0616173963
MESH:D052801 Male Urogenital Diseases Diethylstilbestrol 4.8516002989
MESH:D015674 Mammary Neoplasms, Animal resveratrol 3.6015688416
MESH:D008325 Mammary Neoplasms, Experimental Genistein 10.7414578162 12929590
MESH:D008325 Mammary Neoplasms, Experimental resveratrol 10.748985016 11606380
MESH:D008325 Mammary Neoplasms, Experimental rosiglitazone 10.7416827153
MESH:D008325 Mammary Neoplasms, Experimental salinomycin 10.7419682730
MESH:D008382 Marfan Syndrome Losartan 5.4319430350
MESH:D008527 Medulloblastoma Tretinoin 2.4917453147
MESH:D008545 Melanoma Curcumin 6.0017885582 18462866
MESH:D008545 Melanoma resveratrol 6.0017992120
MESH:D008545 Melanoma sodium arsenite 6.0019082730 16487513
MESH:D008545 Melanoma Tretinoin 6.0016752155
MESH:D008546 Melanoma, Experimental Acetaminophen 8.8819513568
MESH:D008546 Melanoma, Experimental Acrolein 8.8810803710
MESH:D008569 Memory Disorders Curcumin 3.5417263510
MESH:D008591 Meningomyelocele Tretinoin 3.7916940565
MESH:D008659 Metabolic Diseases resveratrol 3.7917112576
MESH:D024821 Metabolic Syndrome X rosiglitazone 3.8417261469
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.1216801185
MESH:D008679 Metaplasia Ozone 4.4410496685
MESH:D008881 Migraine Disorders Indomethacin 3.2011903285
MESH:D018200 Mixed Tumor, Mullerian Raloxifene 4.8915863610
MESH:D009062 Mouth Neoplasms Indomethacin 3.4812636206
MESH:D009101 Multiple Myeloma Curcumin 13.3619372569
MESH:D009101 Multiple Myeloma Dexamethasone 13.3615867202 15744524 16118317
MESH:D009101 Multiple Myeloma Raloxifene 13.3616497877
MESH:D009101 Multiple Myeloma resveratrol 13.3614749477 17164350 17935668 16490592 16267019 17049120
MESH:D009134 Muscular Atrophy, Spinal Curcumin 10.2617962980
MESH:D009134 Muscular Atrophy, Spinal resveratrol 10.2617962980
MESH:D009135 Muscular Diseases pirinixic acid 2.8816239165
MESH:D009190 Myelodysplastic Syndromes Dexamethasone 6.189809623
MESH:D009190 Myelodysplastic Syndromes Tretinoin 6.1817596541
OMIM:131440 MYELOPROLIFERATIVE DISORDER, CHRONIC, WITH EOSINOPHILIA marker/mechanism
MESH:D009203 Myocardial Infarction Genistein 10.9917141266
MESH:D009203 Myocardial Infarction Losartan 10.9912692751
MESH:D009203 Myocardial Infarction pirinixic acid 10.9919151258
MESH:D009203 Myocardial Infarction resveratrol 10.9916525036 17015251 17188708 17125593 16317513 16456233
MESH:D017202 Myocardial Ischemia resveratrol 7.2617125593 17015251
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 7.2612213967
MESH:D015428 Myocardial Reperfusion Injury Genistein 6.6917141266
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 6.6916411023
MESH:D009205 Myocarditis resveratrol 4.1117322642
MESH:D009232 Myxoma Raloxifene 4.8916343187
MESH:D009361 Neoplasm Invasiveness Curcumin 3.7518495463
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 7.943581430 9029167
MESH:D009362 Neoplasm Metastasis imatinib 7.9415867366
MESH:D009362 Neoplasm Metastasis Indomethacin 7.9411053908 11239499 16537180
MESH:D009369 Neoplasms Acrolein 15.0617329238
MESH:D009369 Neoplasms Dieldrin 15.068820588
MESH:D009369 Neoplasms Diethylstilbestrol 15.0615313581
MESH:D009369 Neoplasms pirinixic acid 15.0617405874
MESH:D009369 Neoplasms sodium arsenite 15.0611559025
MESH:D009369 Neoplasms Tretinoin 15.0616594593 16946489
MESH:D009374 Neoplasms, Experimental Indomethacin 11.7215625704 10663608
MESH:D009374 Neoplasms, Experimental resveratrol 11.728985016
MESH:D009374 Neoplasms, Experimental sodium arsenite 11.7220056578
MESH:D009376 Neoplasms, Hormone-Dependent Curcumin 9.1912497104
MESH:D009376 Neoplasms, Hormone-Dependent imatinib 9.1917614352
MESH:D009393 Nephritis Acrolein 5.6212653641
MESH:D009397 Nephrocalcinosis Furosemide 5.2115086907
MESH:D009402 Nephrosis, Lipoid Cyclosporine 3.7817954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 2.7319348381 18481113
MESH:D009421 Nervous System Malformations bisphenol A 24.2411399458 16427766
MESH:D009421 Nervous System Malformations Diethylstilbestrol 24.2411399458
MESH:D009421 Nervous System Malformations Genistein 24.2416427766
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 24.2414600291
MESH:D009421 Nervous System Malformations Tretinoin 24.249125849
MESH:D009423 Nervous System Neoplasms Curcumin 4.9718462866
MESH:D009436 Neural Tube Defects sodium arsenite 5.8112854658
MESH:D009436 Neural Tube Defects Tretinoin 5.819142499
MESH:D019636 Neurodegenerative Diseases Acetaminophen 25.8518514411
MESH:D019636 Neurodegenerative Diseases Acrolein 25.8511342003
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 25.8520387270
MESH:D019636 Neurodegenerative Diseases Indomethacin 25.8512349958
MESH:D019636 Neurodegenerative Diseases Oxidopamine 25.8518514411
MESH:D019636 Neurodegenerative Diseases resveratrol 25.8517652729
MESH:D020078 Neurogenic Inflammation resveratrol 3.8017929310
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 4.4520387270
MESH:D009503 Neutropenia Mustard Gas 3.387688884 16761898
MESH:D053206 Nocturnal Enuresis Furosemide 5.2117945291
MESH:D009765 Obesity Curcumin 3.9019297423
MESH:D009765 Obesity pirinixic acid 3.9020558911
MESH:D007752 Obstetric Labor, Premature Indomethacin 4.516374098
MESH:D010003 Osteoarthritis Indomethacin 3.257009135
MESH:D010014 Osteolysis imatinib 5.0915867366
MESH:D010024 Osteoporosis Curcumin 9.4518719352
MESH:D010024 Osteoporosis Genistein 9.4519401787
MESH:D010024 Osteoporosis Raloxifene 9.4517882678 15775268 19059307
MESH:D015663 Osteoporosis, Postmenopausal Genistein 13.4316169203
MESH:D015663 Osteoporosis, Postmenopausal Raloxifene 13.4315579764 17823083 17893378 15758505
MESH:D015663 Osteoporosis, Postmenopausal resveratrol 13.4317513867
MESH:D010049 Ovarian Diseases bisphenol A 4.3411985600
MESH:D010051 Ovarian Neoplasms Curcumin 9.1919020741 18462866
MESH:D010051 Ovarian Neoplasms Genistein 9.1919005980
MESH:D010051 Ovarian Neoplasms sodium arsenite 9.1917306315 15276417
MESH:D010051 Ovarian Neoplasms Tretinoin 9.1916936753
MESH:D010146 Pain Acetaminophen 8.2116870215
MESH:D010146 Pain Indomethacin 8.2117627676 17440234 13679232 3291741
MESH:D010146 Pain Tretinoin 8.2116870215
MESH:D010149 Pain, Postoperative Indomethacin 4.0212538197 18702446
MESH:D010190 Pancreatic Neoplasms Curcumin 7.0019401701 17440100 19196508
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 7.0016540662
MESH:D010190 Pancreatic Neoplasms Tretinoin 7.0015976015
MESH:D010195 Pancreatitis Indomethacin 3.3317883296 15028970
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.0811578682
MESH:D010212 Papilloma cumene hydroperoxide 4.7017234724 12065085
MESH:D010257 Paraneoplastic Syndromes Indomethacin 5.0516537180
MESH:D010300 Parkinson Disease Acrolein 5.1017690948
MESH:D010300 Parkinson Disease Dieldrin 5.1016809432 16112328 11181820 11445065 17291500
MESH:D010302 Parkinson Disease, Secondary Oxidopamine 4.8311771942 15893579
MESH:D020734 Parkinsonian Disorders Indomethacin 3.5512349958
MESH:D051302 Paroxysmal Hemicrania Indomethacin 5.0511903285
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 3.5912520081
MESH:D010437 Peptic Ulcer Indomethacin 4.5011148446
MESH:D010518 Periodontitis Indomethacin 4.2517225004
MESH:D010538 Peritonitis Ozone 3.5016369182
MESH:D010787 Photosensitivity Disorders 4-hydroxy-2-nonenal 11.2611550810
MESH:D010787 Photosensitivity Disorders Acrolein 11.2611550810
MESH:D010900 Pituitary Diseases Diethylstilbestrol 4.5114722030
MESH:D010911 Pituitary Neoplasms Diethylstilbestrol 4.0415687265 16977796
MESH:D011014 Pneumonia Lipopolysaccharides 8.9512224865 11605937
MESH:D011014 Pneumonia Ozone 8.9518381685 18929643 18007984
MESH:D011041 Poisoning Mustard Gas 3.2115727166
MESH:D011141 Polyuria Furosemide 5.0017945291
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 2.9418163543
MESH:D011230 Precancerous Conditions Cyclosporine 7.1012371664
MESH:D011230 Precancerous Conditions Diethylnitrosamine 7.102563599
MESH:D054198 Precursor Cell Lymphoblastic Leukemia-Lymphoma Dexamethasone 6.7221297632
MESH:D054198 Precursor Cell Lymphoblastic Leukemia-Lymphoma imatinib 6.7212476293
MESH:D047928 Premature Birth Indomethacin 4.4917000239
MESH:D011297 Prenatal Exposure Delayed Effects bisphenol A 17.9810548101
MESH:D011297 Prenatal Exposure Delayed Effects Diethylstilbestrol 17.9817184923
MESH:D011297 Prenatal Exposure Delayed Effects resveratrol 17.9816679765
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 17.9811399792 11896295 11222880 11118676
MESH:D019048 Prostatic Intraepithelial Neoplasia bisphenol A 3.6220887781
MESH:D011471 Prostatic Neoplasms bisphenol A 3.1116740699
MESH:D011471 Prostatic Neoplasms Cholecalciferol 3.1117024972
MESH:D011471 Prostatic Neoplasms Coumestrol 3.1116921512
MESH:D011471 Prostatic Neoplasms Curcumin 3.1118226269 12497104 15129424 18769126 18156803 11398177 10851300
MESH:D011471 Prostatic Neoplasms Diethylstilbestrol 3.1115846301 17136230 15046698
MESH:D011471 Prostatic Neoplasms Genistein 3.1115378649 16925846 15256057
MESH:D011471 Prostatic Neoplasms Raloxifene 3.1116220300 16536755 15731164
MESH:D011471 Prostatic Neoplasms resveratrol 3.1117636462 15767336 17718901 17804756 16731767 17675339
MESH:D011471 Prostatic Neoplasms sodium arsenite 3.1116039940
MESH:D011471 Prostatic Neoplasms Vitamin E 3.1115084515
MESH:D011507 Proteinuria Indomethacin 7.3511849393
MESH:D011507 Proteinuria Tretinoin 7.3516636307
MESH:D011537 Pruritus Ethinyl Estradiol 7.3815861022 16919318
MESH:D011537 Pruritus Mustard Gas 7.3818058305
MESH:D011565 Psoriasis Cyclosporine 1.9616882103
MESH:D011625 Pterygium Tretinoin 4.1416723453
MESH:D011629 Puberty, Precocious bisphenol A 4.1410548101
MESH:D011656 Pulmonary Emphysema Curcumin 3.9519168576
MESH:D011658 Pulmonary Fibrosis Mustard Gas 2.6417894541 17620002 17266442 17720292 10334151
MESH:D011693 Purpura Raloxifene 4.8915770314
MESH:D051437 Renal Insufficiency Acrolein 8.9812732208
MESH:D051437 Renal Insufficiency Losartan 8.9815728788
MESH:D051436 Renal Insufficiency, Chronic resveratrol 4.9216325855
MESH:D015427 Reperfusion Injury Furosemide 8.9516526316
MESH:D015427 Reperfusion Injury pirinixic acid 8.9519058328
MESH:D015427 Reperfusion Injury resveratrol 8.9517058453 16314181 17520802 16317513 15827377
MESH:D012120 Respiration Disorders Chlorine 4.5518579056
MESH:D012128 Respiratory Distress Syndrome, Adult Curcumin 11.9010666014 18379247
MESH:D012128 Respiratory Distress Syndrome, Adult Dexamethasone 11.9011700416 18379247
MESH:D012128 Respiratory Distress Syndrome, Adult Furosemide 11.9015912074 12394941 16096441
MESH:D012130 Respiratory Hypersensitivity Lipopolysaccharides 3.2810835634
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.2218990726
MESH:D012208 Rhabdomyosarcoma Tretinoin 3.5016283617 16116481
MESH:D012509 Sarcoma Curcumin 3.5518462866
MESH:D012559 Schizophrenia Methionine 3.5815737665
MESH:D018805 Sepsis Curcumin 3.5418389075
MESH:D012871 Skin Diseases Mustard Gas 4.3012880345 15451306 16961503
MESH:D012871 Skin Diseases Vitamin E 4.3018709164
MESH:D012878 Skin Neoplasms cumene hydroperoxide 14.2217234724 8532709 12065085
MESH:D012878 Skin Neoplasms resveratrol 14.2215837718 8985016
MESH:D012878 Skin Neoplasms sodium arsenite 14.2219524636 18572023
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 14.2216192470
MESH:D012878 Skin Neoplasms Tretinoin 14.2216467112
MESH:D013088 Spermatocele Diethylstilbestrol 9.5216709447 16002989
MESH:D013088 Spermatocele Ethinyl Estradiol 9.5216709447
MESH:D016135 Spinal Dysraphism sodium arsenite 3.2812854658
MESH:D013272 Stomach Diseases Dexamethasone 8.2215472012
MESH:D013272 Stomach Diseases Indomethacin 8.2218209964 15472012 16280098 17207306 10486359 16113693 18545984 15038085 16184426 17160473 10192188 17638125 10215738
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 5.4218456281
MESH:D013274 Stomach Neoplasms Furosemide 5.4217052386
MESH:D013274 Stomach Neoplasms imatinib 5.4215786421
MESH:D013274 Stomach Neoplasms Indomethacin 5.4215609394
MESH:D013274 Stomach Neoplasms Tretinoin 5.4217261132
MESH:D013276 Stomach Ulcer Curcumin 12.5816631530 19188055
MESH:D013276 Stomach Ulcer Dexamethasone 12.5815138204
MESH:D013276 Stomach Ulcer Indomethacin 12.5816755016 18087811 17627676 11729361 17977527 15255614 15104355 11595415 10423059 17657623 16169175 11523592 16631530 18209962 10878458 16150113 18431645 18181030 16934674 18237397 1323529 10750652 15138204 17135157 11906479 18193104 11595431 18543354 17895592 12787963 12077510 14567935 16397915 12500499 17918041 11145282 16252198 12467913 18726076 17654042 18299717 12498302
MESH:D013276 Stomach Ulcer Leukotriene D4 12.581323529
MESH:D020521 Stroke Acrolein 11.5116269634
MESH:D020521 Stroke Raloxifene 11.5116837676
MESH:D020521 Stroke Vitamin E 11.5116517955
OMIM:601367 STROKE, ISCHEMIC resveratrol 3.9116321402
MESH:D019966 Substance-Related Disorders bisphenol A 3.3416684133 16045194
MESH:D013705 Temporomandibular Joint Disorders polyphenols 4.5917997062
MESH:D013921 Thrombocytopenia Lipopolysaccharides 3.6015821434
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.0211994571
MESH:D013927 Thrombosis Ethinyl Estradiol 2.6015669648
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.2412697716
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 13.047505956
MESH:D013964 Thyroid Neoplasms imatinib 13.0416940797
MESH:D013964 Thyroid Neoplasms Indomethacin 13.0414736730 18791128 11352223
MESH:D013964 Thyroid Neoplasms Tretinoin 13.0416026305 17045167
MESH:D013978 Tibial Fractures Raloxifene 4.5519048282
MESH:D014062 Tongue Neoplasms resveratrol 8.0216227395
MESH:D014062 Tongue Neoplasms Tretinoin 8.0216051514
MESH:D014376 Tuberculosis Tretinoin 2.7916040207
MESH:D014456 Ulcer Indomethacin 4.2517380554 10574470
MESH:D001749 Urinary Bladder Neoplasms Curcumin 9.4718593936
MESH:D001749 Urinary Bladder Neoplasms Diethylstilbestrol 9.4716452187 17306315 16712894
MESH:D001749 Urinary Bladder Neoplasms Raloxifene 9.4717572228
MESH:D001749 Urinary Bladder Neoplasms sodium arsenite 9.4717306315 16712894 11723127 16452187
MESH:D014565 Urogenital Neoplasms Curcumin 4.6118462866
MESH:D014570 Urologic Diseases Dichlorodiphenyl Dichloroethylene 5.0816487989
MESH:D014581 Urticaria Acetaminophen 2.3810982225
MESH:D002583 Uterine Cervical Neoplasms Diethylstilbestrol 17.9916175088
MESH:D002583 Uterine Cervical Neoplasms resveratrol 17.9917473185
MESH:D002583 Uterine Cervical Neoplasms sodium arsenite 17.9911813266
MESH:D002583 Uterine Cervical Neoplasms Tretinoin 17.9916129372
MESH:D014591 Uterine Diseases bisphenol A 11.6214652134
MESH:D014591 Uterine Diseases Diethylstilbestrol 11.6214652134
MESH:D014594 Uterine Neoplasms Diethylstilbestrol 12.5215809267 16690809
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 12.5214692618
MESH:D014594 Uterine Neoplasms resveratrol 12.5217044934
MESH:D014604 Uveal Neoplasms Tretinoin 3.9516752155
MESH:D014605 Uveitis Cyclosporine 9.571336536
MESH:D014605 Uveitis Dexamethasone 9.571336536
MESH:D014625 Vaginal Neoplasms Diethylstilbestrol 3.8016002989 16513791
MESH:D014652 Vascular Diseases sodium arsenite 3.7817056641
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 3.9312125929
MESH:D054556 Venous Thromboembolism Raloxifene 4.5516837676
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 2.9514671159 15869587
MESH:D018487 Ventricular Dysfunction, Left resveratrol 3.6717488730
MESH:D014820 Vitiligo Tretinoin 3.4416761959
MESH:D014839 Vomiting Indomethacin 4.0911897121
MESH:D014846 Vulvar Neoplasms Raloxifene 4.8916343187
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 3.5915886252
MESH:D009396 Wilms Tumor Tretinoin 3.4116287080
MESH:D014985 Xerophthalmia Cyclosporine 3.7817120751
Pathway ID Pathway Name
KEGG:04020 Calcium signaling pathway
KEGG:04060 Cytokine-cytokine receptor interaction
KEGG:04510 Focal adhesion
KEGG:04540 Gap junction
KEGG:05214 Glioma
KEGG:04010 MAPK signaling pathway
KEGG:05218 Melanoma
KEGG:05200 Pathways in cancer
KEGG:05215 Prostate cancer
KEGG:04810 Regulation of actin cytoskeleton
REACT:16888 Signaling by PDGF
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA33148
    • Releated gene ID Related gene Name
    PA29519HSP90AA1
    Releated disease ID Related disease Name
    PA443622Carcinoma, Non-Small-Cell Lung
    PA446661Carcinoma, Small Cell
    PA444818Lung Neoplasms
    PA443448Asthenia
    PA443560Breast Neoplasms
    PA443624Carcinoma, Renal Cell
    PA443899Diarrhea
    PA443937Drug Toxicity
    PA444153Fatigue
    PA151958383Gastrointestinal Stromal Tumors
    PA444552Hypertension
    PA445062Neoplasms
    PA445113Neutropenia
    PA444284Glioma
    Releated drug ID Related drug Name
    PA449014cisplatin
    PA131301952gefitinib
    PA10804imatinib
    PA162372840sunitinib
    PA165291492pazopanib
    Drug Bank Top
    Drugbank ID Action Drug Name Description
    DB00102 - Becaplermin Anti-Ulcer Agents;Topical
    DB00398 antagonist Sorafenib Antineoplastic Agents;Protein Kinase Inhibitors;Anticancer Agents
    DB00619 inhibitor Imatinib Antineoplastic Agents;Protein Kinase Inhibitors
    DB01254 inhibitor Dasatinib Protein Kinase Inhibitors
    DB01268 antagonist Sunitinib Antineoplastic Agents;Angiogenesis Inhibitors
    No data
    No data
    No data

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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