AutismKB 2.0

Annotation Detail for NOP58


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Basic Information Top
Gene Symbol:NOP58 ( NOP5,NOP5/NOP58 )
Gene Full Name: NOP58 ribonucleoprotein homolog (yeast)
Band: 2q33.1
Quick LinksEntrez ID:51602; OMIM: NA; Uniprot ID:NOP58_HUMAN; ENSEMBL ID: ENSG00000055044; HGNC ID: 29926
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000643 Ammonium Chloride Ammonium Chloride affects the expression of NOP58 mRNAaffects expression 16483693
D002251 Carbon Tetrachloride Carbon Tetrachloride affects the expression of NOP58 mRNAaffects expression 15963342
D002251 Carbon Tetrachloride Carbon Tetrachloride results in increased expression of NOP58 mRNAincreases expression 16239168
D016572 Cyclosporine Cyclosporine results in increased expression of NOP58 mRNAincreases expression 20106945
D018038 Sodium Selenite Sodium Selenite results in increased expression of NOP58 mRNAincreases expression 18175754
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000138 Acidosis Ammonium Chloride 4.1918287403
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 4.3416227642 18705752 15673190 16050911 15721981 16097048 10355542 16124888 3786805 16011737 15700767 16192424
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 1.8618788625
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 2.7912371664
MESH:D002779 Cholestasis Cyclosporine 3.2119486331
MESH:D019457 Chromosome Breakage Sodium Selenite 5.3115894690
MESH:D003920 Diabetes Mellitus Sodium Selenite 4.1516285004
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 4.303732212 7120509 15968718 6884620 19085960 10915739 16177239 11566570 4309450 15998439 2869522 6623471 9327722 19336974 21278145 15027814 17522070 7179309 7440962 3786805 16227642 10092053
MESH:D056486 Drug-Induced Liver Injury Sodium Selenite 4.3015131321
MESH:D005234 Fatty Liver Carbon Tetrachloride 9.1512631006 19224547 15959796 61145 12795759 16045604 16239168 17595544
MESH:D005234 Fatty Liver Cyclosporine 9.1519224547
MESH:D005355 Fibrosis Carbon Tetrachloride 10.6018705752
MESH:D005355 Fibrosis Cyclosporine 10.6012639820 12168785
MESH:D005885 Gingival Hyperplasia Cyclosporine 4.858708960
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 5.0515720958
MESH:D006505 Hepatitis Carbon Tetrachloride 4.1019110552 19900420
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 5.1616899240
MESH:D006973 Hypertension Cyclosporine 2.2110903974
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 4.6515338365
MESH:D007333 Insulin Resistance Sodium Selenite 3.5214714311
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 5.1615604871
MESH:D007674 Kidney Diseases Cyclosporine 2.5418776723 10903974 8314463
MESH:D007680 Kidney Neoplasms Cyclosporine 3.0812371664
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 3.0017334410 16943688 17174718 16239168 16221502 11408273 21278145 11903743 17157831
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 1.7517525996 14512876 12667390 12632514 17766677 17557913 15650968 18472094 18279442 16015684 12586293 16136751 17900296 18006644 15996030 14620537 13678700 15057751 15893842 14724832 18205269 14716833 17708605 15730626 16097048 18277467 10355542 18412020 15818738 18395095 15362042 18472332 15123356 15673190 17565644 18420326 12741479 17869086 18263696 15370692 17761835 18210741 15052691 15925388 17631135 12649538 15959796 18705752 18429990 12546737 18156304 18054572 12958196 18166357 16116963 16248980 17721639 15931870 16027843 18251166 16011737 17481882 18187930 12898905 18317297 16638106 18339082 12666154 17976157 18395914 16192424 14716496 17640975 12609069 12445421 18376398 15876570 12389079 16033810 17922224 12632512 14748882 18418968 17714472 17805973 17698563 17944888 11481614 12445418 15338365 20821823 17823541 18481824
MESH:D008107 Liver Diseases Carbon Tetrachloride 2.1516246199 16964402 15830285 17285989 15720792
MESH:D017093 Liver Failure Carbon Tetrachloride 4.7315123358
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 4.0816899240 14706259
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 2.3419294768
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 2.8415583823 12014681
MESH:D016393 Lymphoma, B-Cell Sodium Selenite 4.5214737004
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 5.5116801185
MESH:D009402 Nephrosis, Lipoid Cyclosporine 5.1617954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.6519348381 18481113
MESH:D011230 Precancerous Conditions Cyclosporine 3.5912371664
MESH:D011471 Prostatic Neoplasms Sodium Selenite 3.3318760546
MESH:D011565 Psoriasis Cyclosporine 2.3316882103
MESH:D014605 Uveitis Cyclosporine 4.711336536
MESH:D014985 Xerophthalmia Cyclosporine 5.1617120751
Pathway ID Pathway Name
KEGG:03008 Ribosome biogenesis in eukaryotes
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Syndromic Genes

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AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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