AutismKB 2.0

Annotation Detail for ERGIC3


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Basic Information Top
Gene Symbol:ERGIC3 ( C20orf47,CGI-54,Erv46,NY-BR-84,PRO0989,SDBCAG84,dJ477O4.2 )
Gene Full Name: ERGIC and golgi 3
Band: 20q11.22
Quick LinksEntrez ID:51614; OMIM: NA; Uniprot ID:ERGI3_HUMAN; ENSEMBL ID: ENSG00000125991; HGNC ID: 15927
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C016403 2,4-dinitrotoluene 2,4-dinitrotoluene affects the expression of ERGIC3 mRNAaffects expression 21346803
D001564 Benzo(a)pyrene Benzo(a)pyrene results in decreased expression of ERGIC3 mRNAdecreases expression 20498004
D004997 Ethinyl Estradiol Ethinyl Estradiol affects the expression of ERGIC3 mRNAaffects expression 17555576
D015741 Metribolone Metribolone results in increased expression of ERGIC3 mRNAincreases expression 17010196
D012643 Selenium Selenium results in increased expression of ERGIC3 mRNAincreases expression 19244175
D013629 Tamoxifen Tamoxifen affects the expression of ERGIC3 mRNAaffects expression 17555576
D014212 Tretinoin Tretinoin results in increased expression of ERGIC3 mRNAincreases expression 16054129
D019287 Zinc Sulfate Zinc Sulfate results in decreased expression of ERGIC3 mRNAdecreases expression 16330358
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Tamoxifen 4.9214745880
MESH:D000138 Acidosis Zinc Sulfate 5.247265320
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 4.3217505938
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 4.3520127859 20464547
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 4.3514692618
MESH:D000236 Adenoma Benzo(a)pyrene 2.786695378
MESH:D000505 Alopecia Tretinoin 3.8115955085
MESH:D000860 Anoxia Zinc Sulfate 5.367265320
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 4.3819183758
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 3.7711256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 7.6715885639
MESH:D001169 Arthritis, Experimental Tretinoin 7.6716412693
MESH:D001172 Arthritis, Rheumatoid Tretinoin 2.3116292516
MESH:D001249 Asthma Tretinoin 2.4016456186
MESH:D001471 Barrett Esophagus Tretinoin 4.6816935849
MESH:D001778 Blood Coagulation Disorders Tretinoin 3.8516197459 16206674
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 1.8720146248 17474063
MESH:D001943 Breast Neoplasms Tamoxifen 1.8719288272 15668708 19200415 15565566 20390343 19011961 19410462 19142967 21138602 19115204 19059307 11161223 20859285 18815881 17049068 18629630 18984771 20544844 17242785 19221464 16818667 17893378 19066611 18855134 18821012 16202921 19244106 19289846 20005174 19155303 19189210 20135344 18997820 18425577 17261762 18351453 17440819 19487384 16873071 19103187 20065188 16273361 21152245 19084267 19189212
MESH:D001943 Breast Neoplasms Tretinoin 1.8716443354 16873071 16166294
MESH:D001997 Bronchopulmonary Dysplasia Tretinoin 4.9316813970
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 4.8119066611
MESH:D018236 Carcinoma, Embryonal Tretinoin 5.5416168501
MESH:D006528 Carcinoma, Hepatocellular 2,4-dinitrotoluene 4.7616705839
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 4.7616924424
MESH:D006528 Carcinoma, Hepatocellular Tretinoin 4.761917145
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 4.7620419170
MESH:D002294 Carcinoma, Squamous Cell Tretinoin 4.7616096774 16051514
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 3.8417572228
MESH:D002386 Cataract Tretinoin 3.2217460283
MESH:D018290 Cervical Intraepithelial Neoplasia Tretinoin 4.9316129372
MESH:D002779 Cholestasis Ethinyl Estradiol 3.0517333356 16105132 11677210 17681005 16919318 17110522 15861022
MESH:D002822 Choriocarcinoma Tretinoin 5.5416461808
MESH:D002972 Cleft Palate Tretinoin 2.759407595
MESH:D003092 Colitis Selenium 10.5417936198
MESH:D003092 Colitis Tretinoin 10.5417035595
MESH:D019465 Craniofacial Abnormalities Tretinoin 1.838800419 9125849 16925845 9224671 10589399 9211117 17551590 9664655 9142499 14991402
MESH:D003490 Cyanosis 2,4-dinitrotoluene 4.3218551238
MESH:D003711 Demyelinating Diseases Tamoxifen 4.6719031437
MESH:D003928 Diabetic Nephropathies Tamoxifen 3.6919279558
MESH:D056486 Drug-Induced Liver Injury 2,4-dinitrotoluene 4.1321346803 18551238
MESH:D056486 Drug-Induced Liver Injury Selenium 4.1315131321
MESH:D004489 Edema, Cardiac Tretinoin 4.8418230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 9.9012538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 9.9019031437
MESH:D016889 Endometrial Neoplasms Tamoxifen 7.9316202921 17893378 19155303 20544844
MESH:D016889 Endometrial Neoplasms Tretinoin 7.9316569247
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 2.0616530937
MESH:D005124 Eye Abnormalities Tretinoin 3.759664655 16938888
MESH:D005234 Fatty Liver Ethinyl Estradiol 8.5115345470
MESH:D005234 Fatty Liver Tamoxifen 8.5114986274 19224547
MESH:D052776 Female Urogenital Diseases Tamoxifen 3.3716709447
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 4.8714745880
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 4.5219069698
MESH:D005355 Fibrosis Tretinoin 3.8217994277
MESH:D005909 Glioblastoma Tretinoin 3.1517312396
MESH:D006258 Head and Neck Neoplasms Tretinoin 3.3416096774
MESH:D006317 Hearing Loss, Noise-Induced Tretinoin 5.5416084493
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 7.0320471113
MESH:D006330 Heart Defects, Congenital Tretinoin 7.039664655 14991402
MESH:D006333 Heart Failure Selenium 3.2117162251
MESH:D006527 Hepatolenticular Degeneration Zinc Sulfate 5.3017063115
MESH:D006930 Hyperalgesia Tretinoin 3.4016870215
MESH:D017681 Hypereosinophilic Syndrome Tretinoin 4.8816778211
MESH:D007021 Hypospadias Ethinyl Estradiol 4.1216569931 16945680
MESH:D007022 Hypotension Zinc Sulfate 4.737265320
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.7212013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 2.6417937319
MESH:D007249 Inflammation Tamoxifen 2.4619457130
MESH:D007251 Influenza, Human Selenium 4.5716624496
MESH:D007410 Intestinal Diseases Tretinoin 4.0717994277
MESH:D007569 Jaw Abnormalities Tretinoin 4.1417551590 15992940
MESH:D007676 Kidney Failure, Chronic Selenium 4.1316518626
MESH:D007680 Kidney Neoplasms 2,4-dinitrotoluene 8.0716705839
MESH:D007680 Kidney Neoplasms Tamoxifen 8.0718625569
MESH:D016773 Leishmaniasis, Cutaneous Zinc Sulfate 4.4615237267
MESH:D007938 Leukemia Tretinoin 2.8717143497
MESH:D007951 Leukemia, Myeloid Tretinoin 3.9416482212 19285840 16932348
MESH:D015470 Leukemia, Myeloid, Acute Tretinoin 2.1119850784 16294345 17596541
MESH:D015473 Leukemia, Promyelocytic, Acute Tretinoin 3.3017361223 16331271 16891316 16935935 17712046 12679006 17107899 16788101 17649720 17301526 17339181 17506722 16823087 17368321 17294898 16766008 19642359 19225113 9834237 15748426 16140955 19075265 17217047 19029980 19035177
MESH:D017880 Limb Deformities, Congenital Tretinoin 3.479224671
MESH:D008064 Lipidoses Tamoxifen 3.3217567588 15342952
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 2.5518564211
MESH:D008106 Liver Cirrhosis, Experimental Tretinoin 2.5516248980 18397230
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 4.7720195826 21137059
MESH:D008113 Liver Neoplasms Tamoxifen 4.7716684651
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 2.4218816296 20464547 18569708 17053015 6695378 20869020 20135361 20064080 18520028
MESH:D008175 Lung Neoplasms Tamoxifen 2.4218625569
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 4.1019428831
MESH:D008325 Mammary Neoplasms, Experimental Selenium 6.5315318939
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 6.5311731420 19196722 19196723 14580682 16827153
MESH:D020149 Manganese Poisoning Tamoxifen 4.9219453300
MESH:D008527 Medulloblastoma Tretinoin 2.8617453147
MESH:D008545 Melanoma Tamoxifen 3.3912393984 19393235
MESH:D008545 Melanoma Tretinoin 3.3916752155
MESH:D018328 Melanoma, Amelanotic Tamoxifen 4.5215990972
MESH:D008591 Meningomyelocele Tretinoin 4.7316940565
MESH:D008654 Mesothelioma Selenium 2.8715107826
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 3.3716381670
MESH:D009190 Myelodysplastic Syndromes Tretinoin 3.2017596541
MESH:D009336 Necrosis 2,4-dinitrotoluene 4.2018551238
MESH:D009362 Neoplasm Metastasis Tamoxifen 2.6319393235
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.5819410462
MESH:D009369 Neoplasms Benzo(a)pyrene 5.3411141357
MESH:D009369 Neoplasms Tretinoin 5.3416946489 16594593
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 4.3819200415 19189210 19196722
MESH:D009421 Nervous System Malformations Tretinoin 4.069125849
MESH:D009436 Neural Tube Defects Tretinoin 3.209142499
MESH:D009784 Occupational Diseases 2,4-dinitrotoluene 3.6612819281 16049721
MESH:D010051 Ovarian Neoplasms Tretinoin 2.4016936753
MESH:D010146 Pain Tretinoin 3.1016870215
MESH:D010190 Pancreatic Neoplasms Tretinoin 2.5315976015
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.9511578682
MESH:D010954 Plasmacytoma Selenium 5.2715087411
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 3.0817292933
MESH:D011471 Prostatic Neoplasms Tamoxifen 3.0815067354
MESH:D011507 Proteinuria Tretinoin 3.8616636307
MESH:D011537 Pruritus Ethinyl Estradiol 3.6515861022 16919318
MESH:D011625 Pterygium Tretinoin 5.1316723453
MESH:D012208 Rhabdomyosarcoma Tretinoin 4.3616283617 16116481
MESH:D012640 Seizures 2,4-dinitrotoluene 2.6818551238
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 6.0110029692 19755658
MESH:D012878 Skin Neoplasms Tretinoin 6.0116467112
MESH:D013088 Spermatocele Ethinyl Estradiol 12.8516709447
MESH:D013088 Spermatocele Tamoxifen 12.8516709447
MESH:D013119 Spinal Cord Injuries Tamoxifen 4.3819457130
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 2.3920155912 2093021
MESH:D013274 Stomach Neoplasms Tretinoin 2.3917261132
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.8811994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.3715669648
MESH:D013964 Thyroid Neoplasms Tretinoin 3.2117045167 16026305
MESH:D014062 Tongue Neoplasms Tretinoin 4.0216051514
MESH:D014376 Tuberculosis Tretinoin 3.3616040207
MESH:D001749 Urinary Bladder Neoplasms 2,4-dinitrotoluene 8.7516049721
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 8.7517053015
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 8.7517572228 8653321 16712894
MESH:D014571 Urologic Neoplasms 2,4-dinitrotoluene 4.6510091137
MESH:D002583 Uterine Cervical Neoplasms Tretinoin 3.9016129372
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 3.5814692618
MESH:D014604 Uveal Neoplasms Tretinoin 4.9916752155
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.7814671159 15869587
MESH:D014820 Vitiligo Tretinoin 4.3416761959
MESH:D009396 Wilms Tumor Tretinoin 4.1816287080
No data
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA38050
    • No data
    Releated disease ID Related disease Name
    PA446155Precursor Cell Lymphoblastic Leukemia-Lymphoma
    PA443756Colonic Neoplasms
    No data
    Drug Bank Top

    Simple Query:


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    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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