AutismKB 2.0

Annotation Detail for SLC25A39


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:SLC25A39 ( CGI69,FLJ22407 )
Gene Full Name: solute carrier family 25, member 39
Band: 17q21.31
Quick LinksEntrez ID:51629; OMIM: 610820; Uniprot ID:S2539_HUMAN; ENSEMBL ID: ENSG00000013306; HGNC ID: 24279
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D001564 Benzo(a)pyrene Benzo(a)pyrene results in decreased expression of SLC25A39 mRNAdecreases expression 20106945
C006253 pirinixic acid pirinixic acid results in increased expression of SLC25A39 mRNAincreases expression 17426115
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of SLC25A39 mRNAdecreases expression 19465110
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 3.5915322242 14514962 11752688
MESH:D055371 Acute Lung Injury pirinixic acid 3.6418653653
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 2.0620127859 20464547
MESH:D000236 Adenoma Benzo(a)pyrene 2.886695378
MESH:D018248 Adenoma, Liver Cell pirinixic acid 12.5116434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 12.5116835633
MESH:D000740 Anemia Tetrachlorodibenzodioxin 3.3911748828
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 4.7319183758
MESH:D001778 Blood Coagulation Disorders pirinixic acid 10.4219483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 10.4212125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 4.6615340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 3.0215746008
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 1.8620146248 17474063
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 1.8620435547
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 3.1616835633
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 2.1420419170
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.5818850075 18670907 16120746
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 3.5816835633
MESH:D002779 Cholestasis pirinixic acid 3.1519176532
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 2.2515668235 15340226 8697196 16354765 12621046
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 3.4817141729 14669216
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 1.2710048152 20055451 15322242
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.5918249437
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 1.7417107852
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 1.6220420201
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 3.0911462148
MESH:D004487 Edema pirinixic acid 8.1812083418
MESH:D004487 Edema Tetrachlorodibenzodioxin 8.1812711302 11000095
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 4.7715322242 18230668 16714409
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 3.479294722 10568697
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 2.0916530937
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 3.3411564622
MESH:D005234 Fatty Liver pirinixic acid 3.2519236843 20131406
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 4.1111858732
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 3.6020067830
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 5.4610696789
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 7.1120471113
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 7.1111294989 10048152
MESH:D006333 Heart Failure pirinixic acid 2.7820558911
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.8211000095
MESH:D006529 Hepatomegaly pirinixic acid 10.5319176532 19772884 16221962 18467677
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 10.5316120746 12621046 15340226
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 4.918697196 16354765 16959395 15340226 18606429
MESH:D006943 Hyperglycemia pirinixic acid 3.6320558911
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 2.0318670907 18850075
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 2.0412200463 12878042
MESH:D007333 Insulin Resistance pirinixic acid 2.9016306350
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 3.8216580747
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 2.2415474484
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 2.2412878042
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 8.1020195826 21137059
MESH:D008113 Liver Neoplasms pirinixic acid 8.1016377806 20007298 15890375
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 8.1016984957
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 2.3512151625
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 2.286695378 20464547 20869020 18816296 20135361 17053015 18569708 20064080 18520028
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 2.2811884234 19555203
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 3.5316381670
MESH:D009135 Muscular Diseases pirinixic acid 4.1616239165
MESH:D009203 Myocardial Infarction pirinixic acid 2.2919151258
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 3.3812213967
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 3.2916411023
MESH:D009369 Neoplasms Benzo(a)pyrene 5.4411141357
MESH:D009369 Neoplasms pirinixic acid 5.4417405874
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 3.8014600291
MESH:D009765 Obesity pirinixic acid 1.8920558911
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 5.1212520081
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 4.1418163543
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 3.9311118676 11399792 11896295 11222880
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 2.9017292933
MESH:D015427 Reperfusion Injury pirinixic acid 2.5619058328
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 4.4218990726
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 6.0510029692 19755658
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 6.0516192470
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 1.5620155912 2093021
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 4.7712697716
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 2.3117053015
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 5.4612125929
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 5.1215886252
No data
Pharmacogenomics Knowledge Base Top
Drug Bank Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved