Annotation Detail for ASB4
Basic Information Top
| Gene Symbol: | ASB4 ( ASB-4,MGC142039,MGC142041 ) |
|---|---|
| Gene Full Name: | ankyrin repeat and SOCS box-containing 4 |
| Band: | 7q21.3 |
| Quick Links | Entrez ID:51666; OMIM: 605761; Uniprot ID:ASB4_HUMAN; ENSEMBL ID: ENSG00000005981; HGNC ID: 16009 |
| Relate to Another Database: | SFARIGene; denovo-db |
Related Pathway Information| Chemical ID | Chemical Name | Interaction | Interaction Action | Publication |
|---|---|---|---|---|
| D002251 | Carbon Tetrachloride | Carbon Tetrachloride results in decreased expression of ASB4 mRNA | decreases expression | 17484886 |
| D010656 | Phenylephrine | Phenylephrine results in increased expression of ASB4 mRNA | increases expression | 18158353 |
| Disease ID | Disease Name | Direct Evidence | Inference Chemical Name | Inference Score | Publication |
|---|---|---|---|---|---|
| MESH:D001145 | Arrhythmias, Cardiac | Phenylephrine | 4.62 | 17460149 | |
| MESH:D001919 | Bradycardia | Phenylephrine | 5.43 | 15306635 | |
| MESH:D002252 | Carbon Tetrachloride Poisoning | Carbon Tetrachloride | 4.54 | 18705752 16227642 16011737 15673190 16097048 15700767 16124888 15721981 10355542 16192424 3786805 16050911 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Carbon Tetrachloride | 1.86 | 18788625 | |
| MESH:D006332 | Cardiomegaly | Phenylephrine | 3.76 | 17124262 16170337 11179087 11754973 15728586 17287366 | |
| MESH:D056486 | Drug-Induced Liver Injury | Carbon Tetrachloride | 2.14 | 4309450 2869522 7440962 19336974 9327722 11566570 10915739 10092053 21278145 7179309 15968718 15027814 17522070 6884620 16177239 19085960 7120509 3732212 3786805 6623471 16227642 15998439 | |
| MESH:D005234 | Fatty Liver | Carbon Tetrachloride | 3.72 | 61145 17595544 16239168 12795759 19224547 15959796 16045604 12631006 | |
| MESH:D005355 | Fibrosis | Carbon Tetrachloride | 4.22 | 18705752 | |
| MESH:D006505 | Hepatitis | Carbon Tetrachloride | 4.27 | 19110552 19900420 | |
| MESH:D006932 | Hyperbilirubinemia | Carbon Tetrachloride | 5.42 | 16899240 | |
| MESH:D006973 | Hypertension | Phenylephrine | 3.21 | 12717712 8949925 | |
| MESH:D006975 | Hypertension, Portal | Carbon Tetrachloride | 4.85 | 15338365 | |
| MESH:D006984 | Hypertrophy | Phenylephrine | 5.11 | 18502941 12791704 | |
| MESH:D008103 | Liver Cirrhosis | Carbon Tetrachloride | 3.04 | 16943688 21278145 16221502 17174718 11408273 17334410 16239168 17157831 11903743 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | Carbon Tetrachloride | 1.76 | 12741479 15673190 18376398 20821823 17761835 17698563 12586293 15730626 15338365 16015684 15123356 17557913 17721639 15370692 18395914 17944888 15996030 15057751 15818738 14620537 17714472 15925388 18412020 14748882 18279442 17922224 18339082 15650968 17805973 15893842 18210741 16248980 18251166 18277467 10355542 11481614 18205269 18705752 17708605 18481824 15362042 16116963 12667390 12445418 16011737 14716496 18187930 12632514 17976157 16638106 17640975 14724832 12445421 12546737 15876570 12389079 12609069 17481882 18395095 17565644 18420326 17869086 16027843 18166357 15959796 18472332 18263696 18054572 14716833 17823541 18429990 18317297 18156304 16136751 12958196 18472094 13678700 15931870 12632512 14512876 16192424 12666154 17631135 12649538 15052691 12898905 17900296 18006644 18418968 16097048 17525996 17766677 16033810 | |
| MESH:D008107 | Liver Diseases | Carbon Tetrachloride | 2.17 | 16964402 16246199 17285989 15830285 15720792 | |
| MESH:D017093 | Liver Failure | Carbon Tetrachloride | 4.93 | 15123358 | |
| MESH:D017114 | Liver Failure, Acute | Carbon Tetrachloride | 4.20 | 16899240 14706259 | |
| MESH:D008113 | Liver Neoplasms | Carbon Tetrachloride | 2.36 | 19294768 | |
| MESH:D008114 | Liver Neoplasms, Experimental | Carbon Tetrachloride | 2.89 | 12014681 15583823 | |
| MESH:D012852 | Sinusitis | Phenylephrine | 5.59 | 7327846 |
| No data |