AutismKB 2.0

Annotation Detail for NUB1


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Basic Information Top
Gene Symbol:NUB1 ( BS4,NUB1L,NYREN18 )
Gene Full Name: negative regulator of ubiquitin-like proteins 1
Band: 7q36.1
Quick LinksEntrez ID:51667; OMIM: 607981; Uniprot ID:NUB1_HUMAN; ENSEMBL ID: ENSG00000013374; HGNC ID: 17623
Relate to Another Database: SFARIGene; denovo-db
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Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene results in decreased expression of NUB1 mRNAdecreases expression 20406850
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene affects the expression of NUB1 mRNAaffects expression 21346803
C029938 nickel sulfate nickel sulfate results in increased expression of NUB1 mRNAincreases expression 16780908
D015215 Zidovudine [Zidovudine co-treated with IFNA1 protein] results in increased expression of NUB1 mRNAaffects cotreatment|increases expression 20370541
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000163 Acquired Immunodeficiency Syndrome Zidovudine 5.489612607
MESH:D055371 Acute Lung Injury nickel sulfate 4.8411954676 16100012 19131640 12718980
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 1.7916705839
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 3.066135515
MESH:D003490 Cyanosis 2,6-dinitrotoluene 4.6718551238
MESH:D017449 Dermatitis, Allergic Contact nickel sulfate 4.3111298694 16823706 16780908
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 2.0618551238 21346803
MESH:D004362 Drug Toxicity Zidovudine 4.3315040536
MESH:D005234 Fatty Liver Zidovudine 4.3918299183
MESH:D006402 Hematologic Diseases Zidovudine 5.2412579204
MESH:D015658 HIV Infections Zidovudine 3.6911363243 11141242 11698656 17358032 20032539
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 8.9716705839
MESH:D007680 Kidney Neoplasms Zidovudine 8.9712579204
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell Zidovudine 4.9020370541
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 2.287678174
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 2.792876784 6135515 2876786
MESH:D008175 Lung Neoplasms Zidovudine 2.4918800350
MESH:D048629 Micronuclei, Chromosome-Defective Zidovudine 6.7117358032
MESH:D009336 Necrosis 2,6-dinitrotoluene 4.6018551238 7678174
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 3.8816049721
MESH:D012640 Seizures 2,6-dinitrotoluene 2.8218551238
MESH:D013274 Stomach Neoplasms Zidovudine 2.4817696246
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 2.4216049721
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 5.0610091137
MESH:D014625 Vaginal Neoplasms Zidovudine 5.4112579204
No data
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AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018