Annotation Detail for ACCN5
Basic Information
Top
| Gene Symbol: | ACCN5 ( HINAC,INAC ) |
|---|
| Gene Full Name: | amiloride-sensitive cation channel 5, intestinal |
|---|
| Band: | 4q31.3-q32 |
|---|
| Quick Links | Entrez ID:51802; OMIM: NA; Uniprot ID:ACCN5_HUMAN; ENSEMBL ID: ENSG00000023843; HGNC ID: |
|---|
| Relate to Another Database: |
SFARIGene;
denovo-db |
| Chemical ID |
Chemical Name |
Interaction |
Interaction Action |
Publication |
|---|
| D000082 |
Acetaminophen |
Acetaminophen affects the expression of ACCN5 mRNA | affects expression | 17562736
|
| D000643 |
Ammonium Chloride |
Ammonium Chloride affects the expression of ACCN5 mRNA | affects expression | 16483693
|
| D010634 |
Phenobarbital |
NR1I3 protein affects the reaction [Phenobarbital results in decreased expression of ACCN5 mRNA] | affects reaction|decreases expression | 19482888
|
| D010634 |
Phenobarbital |
Phenobarbital results in decreased expression of ACCN5 mRNA | decreases expression | 19482888
|
| D010634 |
Phenobarbital |
Phenobarbital results in increased expression of ACCN5 mRNA | increases expression | 19270015
|
| C006253 |
pirinixic acid |
[pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of ACCN5 mRNA | affects binding|increases activity|increases expression | 19710929
|
| C006253 |
pirinixic acid |
pirinixic acid results in increased expression of ACCN5 mRNA | increases expression | 18301758
20059764
|
| C006253 |
pirinixic acid |
PPARA protein promotes the reaction [pirinixic acid results in increased expression of ACCN5 mRNA] | increases expression|increases reaction | 20059764
|
| Disease ID |
Disease Name |
Direct Evidence |
Inference Chemical Name |
Inference Score |
Publication |
|---|
| MESH:D000014 |
Abnormalities, Drug-Induced |
|
Phenobarbital |
4.07 | 6195326 |
| MESH:D000138 |
Acidosis |
|
Ammonium Chloride |
4.19 | 18287403 |
| MESH:D055371 |
Acute Lung Injury |
|
pirinixic acid |
3.58 | 18653653 |
| MESH:D018248 |
Adenoma, Liver Cell |
|
Phenobarbital |
12.32 | 17620307 |
| MESH:D018248 |
Adenoma, Liver Cell |
|
pirinixic acid |
12.32 | 16434500 |
| MESH:D000799 |
Angioedema |
|
Acetaminophen |
4.57 | 10982225 |
| MESH:D001321 |
Autistic Disorder |
|
Acetaminophen |
1.40 | 18445737 |
| MESH:D001778 |
Blood Coagulation Disorders |
|
pirinixic acid |
3.57 | 19483382 |
| MESH:D006528 |
Carcinoma, Hepatocellular |
|
Acetaminophen |
3.02 | 3084413 |
| MESH:D006528 |
Carcinoma, Hepatocellular |
|
Phenobarbital |
3.02 | 6705139 20007298 1701930 17173139 20935162 |
| MESH:D002386 |
Cataract |
|
Acetaminophen |
2.79 | 10977129 |
| MESH:D002493 |
Central Nervous System Diseases |
|
Phenobarbital |
4.81 | 4080065 |
| MESH:D002779 |
Cholestasis |
|
pirinixic acid |
3.12 | 19176532 |
| MESH:D003876 |
Dermatitis, Atopic |
|
pirinixic acid |
2.57 | 18249437 |
| MESH:D056486 |
Drug-Induced Liver Injury |
|
Acetaminophen |
1.67 | 18071297 12540782 11461765 15619225 16781746 12153990 14725611 14550746 15968718 18713872 11421492 2444490 17522070 19739265 12705907 19923254 12958197 11739529 19416960 11287661 11834606 10915739 19420014 17906064 16393943 11743745 12392966 10663392 19085960 11529661 17562736 16081117 16227642 10774834 19370779 16485898 16109766 19164858 12594235 14986274 16177239 |
| MESH:D056487 |
Drug-Induced Liver Injury, Chronic |
|
Acetaminophen |
4.82 | 19426721 |
| MESH:D004421 |
Dystonia |
|
Phenobarbital |
4.47 | 1851702 |
| MESH:D004487 |
Edema |
|
pirinixic acid |
2.90 | 12083418 |
| MESH:D004831 |
Epilepsies, Myoclonic |
|
Phenobarbital |
4.67 | 3659116 |
| MESH:D004828 |
Epilepsies, Partial |
|
Phenobarbital |
4.59 | 3922381 11558140 |
| MESH:D004827 |
Epilepsy |
|
Phenobarbital |
3.06 | 20417680 |
| MESH:D004832 |
Epilepsy, Absence |
|
Phenobarbital |
3.91 | 6401628 |
| MESH:D017029 |
Epilepsy, Complex Partial |
|
Phenobarbital |
4.81 | 7750514 |
| MESH:D004830 |
Epilepsy, Tonic-Clonic |
|
Phenobarbital |
4.65 | 3659116 |
| MESH:D005234 |
Fatty Liver |
|
pirinixic acid |
3.19 | 19236843 20131406 |
| MESH:D005756 |
Gastritis |
|
Acetaminophen |
4.40 | 16983495 |
| MESH:D006333 |
Heart Failure |
|
pirinixic acid |
2.76 | 20558911 |
| MESH:D006529 |
Hepatomegaly |
|
Phenobarbital |
10.41 | 16109766 |
| MESH:D006529 |
Hepatomegaly |
|
pirinixic acid |
10.41 | 18467677 16221962 19772884 19176532 |
| MESH:D006930 |
Hyperalgesia |
|
Acetaminophen |
3.02 | 16870215 |
| MESH:D006943 |
Hyperglycemia |
|
pirinixic acid |
3.58 | 20558911 |
| MESH:D007333 |
Insulin Resistance |
|
pirinixic acid |
2.87 | 16306350 |
| MESH:D007674 |
Kidney Diseases |
|
Acetaminophen |
2.40 | 15629191 12587719 |
| MESH:D008103 |
Liver Cirrhosis |
|
Phenobarbital |
3.08 | 21047994 |
| MESH:D008106 |
Liver Cirrhosis, Experimental |
|
pirinixic acid |
1.35 | 15474484 |
| MESH:D008107 |
Liver Diseases |
|
Acetaminophen |
4.20 | 16611625 19460945 12587719 19014921 19784758 12969438 11587558 16610002 |
| MESH:D008107 |
Liver Diseases |
|
Phenobarbital |
4.20 | 19363144 |
| MESH:D017114 |
Liver Failure, Acute |
|
Acetaminophen |
3.63 | 16871587 17185352 |
| MESH:D008113 |
Liver Neoplasms |
|
Phenobarbital |
4.87 | 19812893 19073162 8742319 21047994 19482888 15975961 |
| MESH:D008113 |
Liver Neoplasms |
|
pirinixic acid |
4.87 | 20007298 16377806 15890375 |
| MESH:D008114 |
Liver Neoplasms, Experimental |
|
Phenobarbital |
2.92 | 17172636 18308698 1399818 2563599 6150874 |
| MESH:D008546 |
Melanoma, Experimental |
|
Acetaminophen |
4.13 | 19513568 |
| MESH:D009135 |
Muscular Diseases |
|
pirinixic acid |
4.07 | 16239165 |
| MESH:D009203 |
Myocardial Infarction |
|
pirinixic acid |
2.27 | 19151258 |
| MESH:D015428 |
Myocardial Reperfusion Injury |
|
pirinixic acid |
3.25 | 16411023 |
| MESH:D020191 |
Myoclonic Epilepsies, Progressive |
|
Phenobarbital |
5.11 | 17484760 |
| MESH:D009369 |
Neoplasms |
|
pirinixic acid |
2.11 | 17405874 |
| MESH:D019636 |
Neurodegenerative Diseases |
|
Acetaminophen |
3.21 | 18514411 |
| MESH:D009765 |
Obesity |
|
pirinixic acid |
1.88 | 20558911 |
| MESH:D010018 |
Osteomalacia |
|
Phenobarbital |
5.00 | 17016548 |
| MESH:D010146 |
Pain |
|
Acetaminophen |
2.73 | 16870215 |
| MESH:D010190 |
Pancreatic Neoplasms |
|
Phenobarbital |
2.60 | 16965848 |
| MESH:D011230 |
Precancerous Conditions |
|
Phenobarbital |
3.99 | 2563599 |
| MESH:D019310 |
Pseudolymphoma |
|
Phenobarbital |
5.22 | 12752131 |
| MESH:D015427 |
Reperfusion Injury |
|
pirinixic acid |
2.55 | 19058328 |
| MESH:D012640 |
Seizures |
|
Phenobarbital |
2.95 | 16876388 3137016 4039156 11442880 |
| MESH:D003294 |
Seizures, Febrile |
|
Phenobarbital |
5.45 | 6407741 |
| MESH:D013964 |
Thyroid Neoplasms |
|
Phenobarbital |
3.36 | 1399818 |
| MESH:D014581 |
Urticaria |
|
Acetaminophen |
3.44 | 10982225 |
Related Pathway Information