AutismKB 2.0

Annotation Detail for GALNT7


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Basic Information Top
Gene Symbol:GALNT7 ( GALNAC-T7,GalNAcT7 )
Gene Full Name: UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 7 (GalNAc-T7)
Band: 4q34.1
Quick LinksEntrez ID:51809; OMIM: 605005; Uniprot ID:GALT7_HUMAN; ENSEMBL ID: ENSG00000109586; HGNC ID: 4129
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa00512O-Glycan biosynthesis
hsa01100Metabolic pathways
No data
No data
No data
No data
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C009505 4,4'-diaminodiphenylmethane 4,4'-diaminodiphenylmethane affects the expression of GALNT7 mRNAaffects expression 18648102
D016604 Aflatoxin B1 Aflatoxin B1 affects the expression of GALNT7 proteinaffects expression 20106945
D000643 Ammonium Chloride Ammonium Chloride affects the expression of GALNT7 mRNAaffects expression 16483693
D001564 Benzo(a)pyrene Benzo(a)pyrene results in increased expression of GALNT7 mRNAincreases expression 20106945
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of GALNT7 mRNAdecreases expression 19150397
D016572 Cyclosporine Cyclosporine results in increased expression of GALNT7 mRNAincreases expression 20106945
D002945 Cisplatin GALNT7 protein affects the susceptibility to Cisplatinaffects response to substance 16217747
D006830 Hydralazine [Hydralazine co-treated with Valproic Acid] results in increased expression of GALNT7 mRNAaffects cotreatment|increases expression 17183730
D007529 Isoflavones Isoflavones results in decreased expression of GALNT7 mRNAdecreases expression 17374662
D008748 Methylcholanthrene Methylcholanthrene results in increased expression of GALNT7 mRNAincreases expression 20713471
D017239 Paclitaxel GALNT7 protein affects the susceptibility to Paclitaxelaffects response to substance 16217747
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with AHR gene mutant form] results in decreased expression of GALNT7 mRNAaffects cotreatment|decreases expression 19465110
D014635 Valproic Acid [Hydralazine co-treated with Valproic Acid] results in increased expression of GALNT7 mRNAaffects cotreatment|increases expression 17183730
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 8.7015322242 11752688 14514962
MESH:D000014 Abnormalities, Drug-Induced Valproic Acid 8.708875741
MESH:D000015 Abnormalities, Multiple Valproic Acid 4.0119490988
MESH:D000138 Acidosis Ammonium Chloride 3.6818287403
MESH:D058186 Acute Kidney Injury Cisplatin 4.0415814532 17670903 12690470
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 4.5920464547 20127859
MESH:D000230 Adenocarcinoma Cisplatin 4.5911798837 17638652
MESH:D000236 Adenoma 4,4'-diaminodiphenylmethane 11.483712494
MESH:D000236 Adenoma Benzo(a)pyrene 11.486695378
MESH:D000236 Adenoma Methylcholanthrene 11.486695378 10545420
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 3.4916835633
MESH:D000505 Alopecia Isoflavones 4.7817569567
MESH:D000550 Amblyopia Valproic Acid 5.3717688650
MESH:D000740 Anemia Tetrachlorodibenzodioxin 3.0211748828
MESH:D001008 Anxiety Disorders Valproic Acid 3.6417497229
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 4.1819183758
MESH:D050197 Atherosclerosis Methylcholanthrene 3.5011922910
MESH:D001321 Autistic Disorder Valproic Acid 2.0018985861 18177632 18558336 18396377 17688650 18940202 20603192 16609825 18316065 17157402 17507914 18775368 19460635 19232924 15238991
MESH:D001660 Biliary Tract Diseases 4,4'-diaminodiphenylmethane 5.1511289319 1440618
MESH:D001714 Bipolar Disorder Valproic Acid 3.1117594078 20046352
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 3.1212125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.9215340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 8.1915746008
MESH:D001848 Bone Diseases, Developmental Valproic Acid 8.198888407
MESH:D019046 Bone Marrow Neoplasms Cisplatin 5.0214601052
MESH:D001859 Bone Neoplasms Paclitaxel 4.6515867366
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 2.3817474063 20146248
MESH:D001943 Breast Neoplasms Cisplatin 2.3818382427 19526202
MESH:D001943 Breast Neoplasms Methylcholanthrene 2.3817474063
MESH:D001943 Breast Neoplasms Paclitaxel 2.3811325840 16273361 18234424 18323546 16115903 16244791 18223236 15136595
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 2.3820435547
MESH:D002277 Carcinoma Methylcholanthrene 8.5510545420
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 8.5516835633
MESH:D006528 Carcinoma, Hepatocellular 4,4'-diaminodiphenylmethane 6.743581430 7296757
MESH:D006528 Carcinoma, Hepatocellular Aflatoxin B1 6.7412619106 21507988 12907637
MESH:D006528 Carcinoma, Hepatocellular Cisplatin 6.7417982673
MESH:D006528 Carcinoma, Hepatocellular Paclitaxel 6.7416313753
MESH:D002289 Carcinoma, Non-Small-Cell Lung Cisplatin 3.0612023789 16685392
MESH:D002292 Carcinoma, Renal Cell 4,4'-diaminodiphenylmethane 2.717296757
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 4.8320419170
MESH:D002294 Carcinoma, Squamous Cell Cisplatin 4.8317066447 18337622 6189445
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.4118670907 18850075 16120746
MESH:D002318 Cardiovascular Diseases Isoflavones 4.2017689850
MESH:D002471 Cell Transformation, Neoplastic 4,4'-diaminodiphenylmethane 16.517505956
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 16.5120889678
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 16.5112371664
MESH:D002471 Cell Transformation, Neoplastic Methylcholanthrene 16.5116192471
MESH:D002659 Child Development Disorders, Pervasive Valproic Acid 2.7320734317
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 3.2316835633
MESH:D002779 Cholestasis 4,4'-diaminodiphenylmethane 8.0819486331 9022650
MESH:D002779 Cholestasis Cyclosporine 8.0819486331
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 2.138697196 16354765 15340226 12621046 15668235
MESH:D015179 Colorectal Neoplasms Cisplatin 3.7415273666
MESH:D015179 Colorectal Neoplasms Isoflavones 3.7417116718
MESH:D015179 Colorectal Neoplasms Paclitaxel 3.7418802399
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 3.1314669216 17141729
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 2.5010048152 20055451 15322242
MESH:D019465 Craniofacial Abnormalities Valproic Acid 2.5017688650 16575769 8888407
MESH:D017449 Dermatitis, Allergic Contact 4,4'-diaminodiphenylmethane 2.9018759878 12868966 11298694 11906362 8970840 8156756 14531868 2524372
MESH:D003877 Dermatitis, Contact 4,4'-diaminodiphenylmethane 3.582952479 3621924
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 1.6817107852
MESH:D056486 Drug-Induced Liver Injury 4,4'-diaminodiphenylmethane 6.3218648102 18692083 16192314 18289764 6482804 9022650 9653073 11289319 8291058 9328219 7440962 1440618 6679447
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 6.3220420201
MESH:D056486 Drug-Induced Liver Injury Valproic Acid 6.321733752 19641884
MESH:D004362 Drug Toxicity Cisplatin 8.3812649298 19839026 15033597 12231392
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 8.3811462148
MESH:D004421 Dystonia Valproic Acid 4.141851702
MESH:D004487 Edema Tetrachlorodibenzodioxin 2.4611000095 12711302
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 4.0416714409 15322242 18230668
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 3.109294722 10568697
MESH:D004831 Epilepsies, Myoclonic Valproic Acid 4.263659116 17275665
MESH:D004828 Epilepsies, Partial Valproic Acid 4.0516628512 3922381
MESH:D004827 Epilepsy Valproic Acid 2.9718234410 20417680
MESH:D004832 Epilepsy, Absence Valproic Acid 3.666254150 6426943 7562514
MESH:D017029 Epilepsy, Complex Partial Valproic Acid 4.407750514
MESH:D004830 Epilepsy, Tonic-Clonic Valproic Acid 4.183659116
MESH:D004938 Esophageal Neoplasms 4,4'-diaminodiphenylmethane 14.063581430
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 14.0620426865
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 14.0616530937
MESH:D004938 Esophageal Neoplasms Cisplatin 14.0616785472 15464296 17638652 15173087 16481741
MESH:D004938 Esophageal Neoplasms Paclitaxel 14.0616481741
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 3.0711564622
MESH:D005234 Fatty Liver Cyclosporine 8.0319224547
MESH:D005234 Fatty Liver Valproic Acid 8.0314986274 19224547
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.5611858732
MESH:D005315 Fetal Diseases Valproic Acid 5.0216575769
MESH:D005317 Fetal Growth Retardation Valproic Acid 4.2318558336 8888407
MESH:D005350 Fibroma 4,4'-diaminodiphenylmethane 5.156705139
MESH:D005354 Fibrosarcoma Methylcholanthrene 5.0614633661 10962813
MESH:D005355 Fibrosis Cyclosporine 8.8312168785 12639820
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 8.8320067830
MESH:D005885 Gingival Hyperplasia Cyclosporine 4.348708960
MESH:D006042 Goiter 4,4'-diaminodiphenylmethane 4.127505956
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.7310696789
MESH:D006258 Head and Neck Neoplasms Cisplatin 3.7715102660 15464296
MESH:D034381 Hearing Loss Cisplatin 4.3719898482
MESH:D006319 Hearing Loss, Sensorineural Cisplatin 4.4915464296
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 6.5820471113
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 6.5810048152 11294989
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.5415720958
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.4211000095
MESH:D006505 Hepatitis 4,4'-diaminodiphenylmethane 3.616705139
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 3.0012621046 15340226 16120746
MESH:D006689 Hodgkin Disease Cisplatin 3.6616170182 16200630
MESH:D019584 Hot Flashes Isoflavones 5.1114716179 17290160
MESH:D006849 Hydrocephalus Valproic Acid 4.9817688650
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 4.188697196 16959395 15340226 16354765 18606429
MESH:D006965 Hyperplasia 4,4'-diaminodiphenylmethane 4.0415034207
MESH:D006973 Hypertension Cyclosporine 5.0410903974
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 5.0418670907 18850075
MESH:D046110 Hypertension, Pregnancy-Induced Hydralazine 4.7316612254
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 1.8912200463 12878042
MESH:D007565 Jaundice 4,4'-diaminodiphenylmethane 5.158074119 9022650
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 3.4216580747
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.5815604871
MESH:D007673 Kidney Cortex Necrosis Cisplatin 5.2715464296
MESH:D007674 Kidney Diseases Cisplatin 6.3318289764 12649298 15190930 19839026 12231392
MESH:D007674 Kidney Diseases Cyclosporine 6.3318776723 10903974 8314463
MESH:D007680 Kidney Neoplasms 4,4'-diaminodiphenylmethane 7.506582329
MESH:D007680 Kidney Neoplasms Cyclosporine 7.5012371664
MESH:D007683 Kidney Tubular Necrosis, Acute Cisplatin 4.9311231351
MESH:D015470 Leukemia, Myeloid, Acute Valproic Acid 2.1616294345 17596541
MESH:D008080 Liposarcoma Paclitaxel 4.9117353645
MESH:D008105 Liver Cirrhosis, Biliary 4,4'-diaminodiphenylmethane 3.2415034207 9327722
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 1.2412878042
MESH:D008113 Liver Neoplasms Aflatoxin B1 7.559163691 15890375 2125692 18177683
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 7.5520195826 21137059
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 7.5516984957
MESH:D008114 Liver Neoplasms, Experimental 4,4'-diaminodiphenylmethane 14.56598648 3712494 6587162 1399818
MESH:D008114 Liver Neoplasms, Experimental Aflatoxin B1 14.568603461
MESH:D008114 Liver Neoplasms, Experimental Methylcholanthrene 14.56598648 1399818
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 14.5612151625
MESH:D017563 Lung Diseases, Interstitial Valproic Acid 4.4017228818
MESH:D008175 Lung Neoplasms Aflatoxin B1 6.7014755239
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 6.7018569708 17053015 20464547 20135361 18816296 6695378 20064080 18520028 20869020
MESH:D008175 Lung Neoplasms Cisplatin 6.706189445 11798837 17225452
MESH:D008175 Lung Neoplasms Methylcholanthrene 6.7010545420 7750092 11893704 16271038 6695378 15390079 21163286 9230183 20512841 20970405 17909032 16337739 1399818
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 6.7011884234 19555203
MESH:D008228 Lymphoma, Non-Hodgkin Paclitaxel 4.1614749477
MESH:D008545 Melanoma Cisplatin 3.7816432458 12374674 16809738 18176117 15577323 18332650 18505091 12393984 17023156 12883367 11135225 17761969 16248763
MESH:D008545 Melanoma Paclitaxel 3.7816342250 12025231 12040289
MESH:D018328 Melanoma, Amelanotic Cisplatin 4.8915990972
MESH:D008654 Mesothelioma Cisplatin 3.2717638057
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.9216801185
MESH:D008881 Migraine Disorders Valproic Acid 3.2518765137 18803445
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 3.2516381670
MESH:D009101 Multiple Myeloma Paclitaxel 3.7414749477
MESH:D009139 Musculoskeletal Abnormalities Valproic Acid 4.118888407
MESH:D009190 Myelodysplastic Syndromes Valproic Acid 3.2017596541
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 3.0812213967
MESH:D009362 Neoplasm Metastasis 4,4'-diaminodiphenylmethane 6.053581430
MESH:D009362 Neoplasm Metastasis Paclitaxel 6.0515867366
MESH:D009369 Neoplasms Benzo(a)pyrene 5.3111141357
MESH:D009369 Neoplasms Cisplatin 5.3116773208
MESH:D009395 Nephritis, Interstitial Cisplatin 4.6315464296
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.5817954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.3619348381 18481113
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 3.3114600291
MESH:D009436 Neural Tube Defects 4,4'-diaminodiphenylmethane 7.436679447
MESH:D009436 Neural Tube Defects Valproic Acid 7.4316359493 8888407
MESH:D009447 Neuroblastoma Cisplatin 3.498761367
MESH:D017599 Neuroectodermal Tumors Cisplatin 4.818761367
MESH:D009784 Occupational Diseases 4,4'-diaminodiphenylmethane 3.504026338 6482804
MESH:D009902 Optic Neuritis 4,4'-diaminodiphenylmethane 5.153988306
MESH:D010014 Osteolysis Paclitaxel 5.1015867366
MESH:D010024 Osteoporosis Isoflavones 4.1516562857
MESH:D010051 Ovarian Neoplasms Cisplatin 5.366897625 19769630 15464296 17225452
MESH:D010051 Ovarian Neoplasms Paclitaxel 5.3611161223
MESH:D010190 Pancreatic Neoplasms Cisplatin 3.0219003803
MESH:D010212 Papilloma 4,4'-diaminodiphenylmethane 3.597296757
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.3812520081
MESH:D010523 Peripheral Nervous System Diseases Cisplatin 4.4015464296
MESH:D010787 Photosensitivity Disorders 4,4'-diaminodiphenylmethane 4.606228378
MESH:D010997 Pleural Neoplasms Cisplatin 5.4817638057
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.6518163543
MESH:D011230 Precancerous Conditions Cyclosporine 3.2912371664
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 9.8611222880 11118676 11399792 11896295
MESH:D011297 Prenatal Exposure Delayed Effects Valproic Acid 9.8620603192
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 2.7517292933
MESH:D011471 Prostatic Neoplasms Isoflavones 2.7517571952 16365062 17219775 17374662
MESH:D011471 Prostatic Neoplasms Paclitaxel 2.7516729912 17172428 17136230 16356831
MESH:D019310 Pseudolymphoma Valproic Acid 4.6712752131 11422049
MESH:D011565 Psoriasis Cyclosporine 2.2516882103
MESH:D051437 Renal Insufficiency Cisplatin 4.5115464296
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.9318990726
MESH:D012162 Retinal Degeneration 4,4'-diaminodiphenylmethane 3.433692021
MESH:D012208 Rhabdomyosarcoma Valproic Acid 4.2619155313
MESH:D012512 Sarcoma, Ewing's Cisplatin 4.5214601052
MESH:D012559 Schizophrenia Valproic Acid 2.0819110320 15737665
MESH:D012640 Seizures Valproic Acid 2.7911044598 15475178 14763951 11738929 3137016 16876388 1511512 17978042
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 5.5919755658 10029692
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 5.5916192470
MESH:D055752 Small Cell Lung Carcinoma Cisplatin 5.4815464296
MESH:D016135 Spinal Dysraphism Valproic Acid 3.8419490988
MESH:D013226 Status Epilepticus Valproic Acid 4.6712833885
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 3.5320155912 2093021
MESH:D013274 Stomach Neoplasms Cisplatin 3.5318396642 15958060 17522103
MESH:D013274 Stomach Neoplasms Paclitaxel 3.5318396642 18506536
MESH:D024801 Tauopathies Paclitaxel 4.9316930453
MESH:D013736 Testicular Neoplasms Cisplatin 4.7217225452 15464296
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 4.0412697716
MESH:D013964 Thyroid Neoplasms 4,4'-diaminodiphenylmethane 2.951399818 6582329 3712494 7505956 6587162
MESH:D014178 Translocation, Genetic Valproic Acid 5.3717262798
MESH:D020194 Unverricht-Lundborg Syndrome Valproic Acid 4.643119515
MESH:D001749 Urinary Bladder Neoplasms 4,4'-diaminodiphenylmethane 8.538074119
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 8.5317053015
MESH:D001749 Urinary Bladder Neoplasms Cisplatin 8.5315464296 12973940 17225452
MESH:D014564 Urogenital Abnormalities Valproic Acid 4.758888407
MESH:D002583 Uterine Cervical Neoplasms Cisplatin 4.2816803524
MESH:D014605 Uveitis Cyclosporine 4.121336536
MESH:D014625 Vaginal Neoplasms Cisplatin 4.7115577323
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.7312125929
MESH:D014839 Vomiting Cisplatin 4.8511897121
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.3815886252
MESH:D014985 Xerophthalmia Cyclosporine 4.5817120751
Pathway ID Pathway Name
KEGG:01100 Metabolic pathways
KEGG:00512 Mucin type O-Glycan biosynthesis
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA28542
    • No data
    Releated disease ID Related disease Name
    PA446155Precursor Cell Lymphoblastic Leukemia-Lymphoma
    Releated drug ID Related drug Name
    PA450379mercaptopurine
    PA450428methotrexate
    Drug Bank Top

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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