AutismKB 2.0

Annotation Detail for ACP1


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Basic Information Top
Gene Symbol:ACP1 ( HAAP,MGC111030,MGC3499 )
Gene Full Name: acid phosphatase 1, soluble
Band: 2p25.3
Quick LinksEntrez ID:52; OMIM: 171500; Uniprot ID:PPAC_HUMAN; ENSEMBL ID: ENSG00000143727; HGNC ID: 122
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa00740Riboflavin metabolism
hsa04520Adherens junction
No data
Pathway IDPathway Name
200185EPHA2 forward signaling
200127PDGFR-beta signaling pathway
No data
No data
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1848Embryoma
1894Abortion
1904Diabetes mellitus
2029Tuberculosis
2053Colon cancer
2151Neuroblastoma
Desease Name
cholesterol
diabetes, type 1
PSYCH
Tourette syndrome
intrauterine growth
IMMUNE
haptoglobin development
METABOLIC
triglycerides
obesity
DEVELOPMENTAL
REPRODUCTION
diabetes, type 2
triglyceride levels
No data
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C016403 2,4-dinitrotoluene 2,4-dinitrotoluene affects the expression of ACP1 mRNAaffects expression 21346803
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene affects the expression of ACP1 mRNAaffects expression 21346803
C009505 4,4'-diaminodiphenylmethane 4,4'-diaminodiphenylmethane results in increased expression of ACP1 mRNAincreases expression 18648102
D000643 Ammonium Chloride Ammonium Chloride affects the expression of ACP1 mRNAaffects expression 16483693
D002104 Cadmium Cadmium results in increased expression of ACP1 mRNAincreases expression 17327700
D019256 Cadmium Chloride Cadmium Chloride results in increased expression of ACP1 mRNAincreases expression 17327700
D004317 Doxorubicin ACP1 protein affects the susceptibility to Doxorubicinaffects response to substance 16217747
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of ACP1 mRNAincreases expression 17555576
D004997 Ethinyl Estradiol [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of ACP1 mRNAaffects cotreatment|increases expression 17942748
D010269 Paraquat Paraquat results in decreased expression of ACP1 mRNAdecreases expression 15458575
D012643 Selenium Selenium results in decreased expression of ACP1 mRNAdecreases expression 19244175
C017947 sodium arsenite sodium arsenite results in increased expression of ACP1 mRNAincreases expression 20308225
D013629 Tamoxifen Tamoxifen affects the expression of ACP1 mRNAaffects expression 17555576
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of ACP1 mRNAaffects cotreatment|increases expression 17942748
D014415 Tunicamycin Tunicamycin results in increased expression of ACP1 mRNAincreases expression 15458575
D014747 Vinblastine ACP1 protein affects the susceptibility to Vinblastineaffects response to substance 16217747
D014810 Vitamin E Vitamin E results in decreased expression of ACP1 mRNAdecreases expression 19244175
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Tamoxifen 4.5814745880
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 2.8715322242 14514962 11752688
MESH:D000138 Acidosis Ammonium Chloride 3.5818287403
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.9717505938
MESH:D000230 Adenocarcinoma Doxorubicin 4.3917418594
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 4.3914692618
MESH:D000236 Adenoma 4,4'-diaminodiphenylmethane 2.753712494
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 3.4016835633
MESH:D000310 Adrenal Gland Neoplasms sodium arsenite 4.7315276417
MESH:D018246 Adrenocortical Adenoma sodium arsenite 4.9316712894 17306315
MESH:D000382 Agricultural Workers' Diseases Paraquat 3.7811874814
MESH:D000419 Albuminuria Doxorubicin 4.5521441931
MESH:D000740 Anemia Tetrachlorodibenzodioxin 2.9511748828
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 3.4811256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 2.6615885639
MESH:D050197 Atherosclerosis Cadmium 3.6415687053
MESH:D001660 Biliary Tract Diseases 4,4'-diaminodiphenylmethane 5.051440618 11289319
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 3.0512125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.8215340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.7615746008
MESH:D019046 Bone Marrow Neoplasms Doxorubicin 4.7314601052
MESH:D001932 Brain Neoplasms Doxorubicin 3.8117150277
MESH:D001943 Breast Neoplasms Doxorubicin 1.8718695136 15692762 18382427 11325840 15939500 15668708 16935488 16115903 15136595 16322301 16264153 16595493 18628466 15993339 19526202 17426702 16096432 15634643 18234424 16826403 17369602 15994142 15567936 17983394
MESH:D001943 Breast Neoplasms Tamoxifen 1.8717261762 19189210 19288272 18815881 19200415 17893378 20859285 18855134 19289846 19221464 17440819 18629630 19410462 19011961 21152245 16202921 19487384 19142967 20544844 19084267 15668708 19189212 20390343 18351453 16873071 20005174 15565566 17242785 19115204 16273361 17049068 19244106 21138602 19066611 18425577 16818667 19155303 18984771 19103187 20135344 20065188 18997820 19059307 11161223 18821012
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 1.8720435547
MESH:D002252 Carbon Tetrachloride Poisoning Vitamin E 3.9416050911
MESH:D002276 Carcinoid Tumor Doxorubicin 4.8416051944
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.8016835633
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 4.5219066611
MESH:D006528 Carcinoma, Hepatocellular 2,4-dinitrotoluene 11.4116705839
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 11.4116705839
MESH:D006528 Carcinoma, Hepatocellular 4,4'-diaminodiphenylmethane 11.417296757 3581430
MESH:D006528 Carcinoma, Hepatocellular Doxorubicin 11.4116023760 16234567 17876044 18059187
MESH:D006528 Carcinoma, Hepatocellular sodium arsenite 11.4117306315 16507464 15276417
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 11.4116924424
MESH:D002292 Carcinoma, Renal Cell 4,4'-diaminodiphenylmethane 10.897296757
MESH:D002292 Carcinoma, Renal Cell Doxorubicin 10.891485588 16201981
MESH:D002292 Carcinoma, Renal Cell Vinblastine 10.891485588
MESH:D002294 Carcinoma, Squamous Cell Doxorubicin 4.826189445
MESH:D002294 Carcinoma, Squamous Cell sodium arsenite 4.8218572023
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 3.6217572228
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.3718850075 18670907 16120746
MESH:D009202 Cardiomyopathies Doxorubicin 3.5316731534 16242529 15476868 17519947 17329180 17131338 17308081 16455267 16651473 16612575 16278810 16364871 17007740 17924179 16952015 17928571 16269455 17974986 17351982 17382496 15792986 15505089 15811867 16109756 18627295
MESH:D002311 Cardiomyopathy, Dilated Doxorubicin 2.9416243910 17334414
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 16.096135515
MESH:D002471 Cell Transformation, Neoplastic 4,4'-diaminodiphenylmethane 16.097505956
MESH:D002471 Cell Transformation, Neoplastic Cadmium 16.0917332340
MESH:D002471 Cell Transformation, Neoplastic sodium arsenite 16.0919524636 20056578
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 3.1616835633
MESH:D002779 Cholestasis 4,4'-diaminodiphenylmethane 7.879022650 19486331
MESH:D002779 Cholestasis Ethinyl Estradiol 7.8717110522 16105132 17681005 16919318 11677210 15861022 17333356
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 2.1016354765 15668235 15340226 12621046 8697196
MESH:D003092 Colitis Selenium 3.7917936198
MESH:D015179 Colorectal Neoplasms Doxorubicin 2.9318259882 18802399
MESH:D015179 Colorectal Neoplasms Vinblastine 2.9318802399
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 3.0614669216 17141729
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 2.4820055451 10048152 15322242
MESH:D019465 Craniofacial Abnormalities Vitamin E 2.4819769572
MESH:D003490 Cyanosis 2,4-dinitrotoluene 10.9418551238
MESH:D003490 Cyanosis 2,6-dinitrotoluene 10.9418551238
MESH:D003711 Demyelinating Diseases Tamoxifen 4.3819031437
MESH:D017449 Dermatitis, Allergic Contact 4,4'-diaminodiphenylmethane 2.8218759878 11298694 8156756 8970840 11906362 14531868 2524372 12868966
MESH:D003877 Dermatitis, Contact 4,4'-diaminodiphenylmethane 3.502952479 3621924
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 1.6717107852
MESH:D003928 Diabetic Nephropathies Tamoxifen 3.4819279558
MESH:D056486 Drug-Induced Liver Injury 2,4-dinitrotoluene 15.2918551238 21346803
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 15.2918551238 21346803
MESH:D056486 Drug-Induced Liver Injury 4,4'-diaminodiphenylmethane 15.291440618 6679447 16192314 9653073 7440962 8291058 18692083 18648102 18289764 9328219 11289319 9022650 6482804
MESH:D056486 Drug-Induced Liver Injury Doxorubicin 15.2917416283
MESH:D056486 Drug-Induced Liver Injury Selenium 15.2915131321
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 15.2920420201
MESH:D004362 Drug Toxicity Doxorubicin 8.1218602426
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 8.1211462148
MESH:C538011 Eales disease Vitamin E 4.739068938
MESH:D004487 Edema Tetrachlorodibenzodioxin 2.3812711302 11000095
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 3.9315322242 16714409 18230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 8.9812538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 8.9819031437
MESH:D016889 Endometrial Neoplasms Doxorubicin 7.5717359293
MESH:D016889 Endometrial Neoplasms Tamoxifen 7.5720544844 16202921 17893378 19155303
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 3.029294722 10568697
MESH:D004719 Endomyocardial Fibrosis Doxorubicin 5.1918037988
MESH:D004938 Esophageal Neoplasms 4,4'-diaminodiphenylmethane 2.113581430
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 3.0111564622
MESH:D005234 Fatty Liver Ethinyl Estradiol 7.7115345470
MESH:D005234 Fatty Liver Tamoxifen 7.7119224547 14986274
MESH:D052776 Female Urogenital Diseases Tamoxifen 3.2416709447
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.4711858732
MESH:D005350 Fibroma 4,4'-diaminodiphenylmethane 5.056705139
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 4.5514745880
MESH:D018222 Fibromatosis, Aggressive Doxorubicin 11.5119069698
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 11.5119069698
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 2.9620067830
MESH:D005833 Genital Neoplasms, Female sodium arsenite 4.7016452187
MESH:D005909 Glioblastoma Doxorubicin 3.3517150277
MESH:D005911 Gliosis Paraquat 5.1911124998
MESH:D006042 Goiter 4,4'-diaminodiphenylmethane 4.047505956
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.6210696789
MESH:D006258 Head and Neck Neoplasms Doxorubicin 3.5315692506
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 6.5711294989 10048152
MESH:D006330 Heart Defects, Congenital Vitamin E 6.5716080930
MESH:D006331 Heart Diseases Doxorubicin 3.4818006777 16244371 16144979 14766674 16244372 18674790 16495754 16707910 16879835 17888722 17875725 12587719 16330681
MESH:D006333 Heart Failure Doxorubicin 7.2517481944
MESH:D006333 Heart Failure Selenium 7.2517162251
MESH:D006394 Hemangiosarcoma Doxorubicin 3.9015692506
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.3411000095
MESH:D006505 Hepatitis 4,4'-diaminodiphenylmethane 3.526705139
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 2.9116120746 15340226 12621046
MESH:D006548 Hernia, Diaphragmatic Vitamin E 2.7016490937 16863852
MESH:D006689 Hodgkin Disease Doxorubicin 12.4215147373 17606976 18501091
MESH:D006689 Hodgkin Disease sodium arsenite 12.4212676792
MESH:D006689 Hodgkin Disease Vinblastine 12.4218501091 18180244
MESH:D019584 Hot Flashes Vitamin E 4.0014716179
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 4.0815340226 16959395 8697196 18606429 16354765
MESH:D006965 Hyperplasia 4,4'-diaminodiphenylmethane 3.9515034207
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 1.9118670907 18850075
MESH:D007021 Hypospadias Ethinyl Estradiol 3.8216945680 16569931
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.4712013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 11.2517937319
MESH:D007248 Infertility, Male Paraquat 11.254850670
MESH:D007248 Infertility, Male sodium arsenite 11.2512646999 15346721
MESH:D007249 Inflammation Tamoxifen 4.8919457130
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 4.8912200463 12878042
MESH:D007251 Influenza, Human Selenium 11.0616624496
MESH:D007251 Influenza, Human Vitamin E 11.0616624496
MESH:D007565 Jaundice 4,4'-diaminodiphenylmethane 5.058074119 9022650
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 3.3416580747
MESH:D007674 Kidney Diseases Cadmium 19.1216226777 16322080 16962696
MESH:D007674 Kidney Diseases Cadmium Chloride 19.1216962696
MESH:D007674 Kidney Diseases Doxorubicin 19.1215369732 16775033 15699352
MESH:D007674 Kidney Diseases sodium arsenite 19.1220008137
MESH:D007674 Kidney Diseases Vitamin E 19.1212488133
MESH:D007676 Kidney Failure, Chronic Doxorubicin 10.0016707910
MESH:D007676 Kidney Failure, Chronic Selenium 10.0016518626
MESH:D007680 Kidney Neoplasms 2,4-dinitrotoluene 17.7816705839
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 17.7816705839
MESH:D007680 Kidney Neoplasms 4,4'-diaminodiphenylmethane 17.786582329
MESH:D007680 Kidney Neoplasms Tamoxifen 17.7818625569
MESH:D004915 Leukemia, Erythroblastic, Acute Doxorubicin 5.1916085563
MESH:D008064 Lipidoses Tamoxifen 3.1615342952 17567588
MESH:D008105 Liver Cirrhosis, Biliary 4,4'-diaminodiphenylmethane 3.2015034207 9327722
MESH:D008106 Liver Cirrhosis, Experimental Doxorubicin 4.9716439617 16595196
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 4.9718564211
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 4.9712878042
MESH:D008106 Liver Cirrhosis, Experimental Vitamin E 4.9716169303
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 10.707678174
MESH:D008113 Liver Neoplasms sodium arsenite 10.7015276417 16712894
MESH:D008113 Liver Neoplasms Tamoxifen 10.7016684651
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 10.7016984957
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 14.136135515 2876786 2876784
MESH:D008114 Liver Neoplasms, Experimental 4,4'-diaminodiphenylmethane 14.131399818 6587162 598648 3712494
MESH:D008114 Liver Neoplasms, Experimental Doxorubicin 14.1316842330 17085340
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 14.1312151625
MESH:D008171 Lung Diseases sodium arsenite 7.4519095001
MESH:D008171 Lung Diseases Vitamin E 7.4516863852
MESH:D008175 Lung Neoplasms Doxorubicin 6.606189445 17418594
MESH:D008175 Lung Neoplasms sodium arsenite 6.6016712894 17077188 19931552 15276417 17306315
MESH:D008175 Lung Neoplasms Tamoxifen 6.6018625569
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 6.6011884234 19555203
MESH:D008175 Lung Neoplasms Vitamin E 6.6011062179
MESH:D008223 Lymphoma Doxorubicin 3.4616098063
MESH:D008228 Lymphoma, Non-Hodgkin Doxorubicin 3.7917654614
MESH:D016399 Lymphoma, T-Cell Doxorubicin 4.5815621674
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 3.7819428831
MESH:D008325 Mammary Neoplasms, Experimental Doxorubicin 10.0315458769
MESH:D008325 Mammary Neoplasms, Experimental Selenium 10.0315318939
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 10.0319196722 19196723 11731420 16827153 14580682
MESH:D020149 Manganese Poisoning Tamoxifen 4.5819453300
MESH:D008545 Melanoma Doxorubicin 7.3616827129
MESH:D008545 Melanoma sodium arsenite 7.3619082730 16487513
MESH:D008545 Melanoma Tamoxifen 7.3619393235 12393984
MESH:D008545 Melanoma Vinblastine 7.3618505091 15577320 16432458 17761969 18176117 18332650 16809738 12374674 16248763 15577323
MESH:D018328 Melanoma, Amelanotic Tamoxifen 4.2015990972
MESH:D008654 Mesothelioma Doxorubicin 6.2917638057
MESH:D008654 Mesothelioma Selenium 6.2915107826
MESH:D028361 Mitochondrial Diseases Doxorubicin 4.5015792986
MESH:D052016 Mucositis Doxorubicin 4.8117415656
MESH:D009203 Myocardial Infarction Doxorubicin 2.9519429709 15857846
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 3.0212213967
MESH:D009336 Necrosis 2,4-dinitrotoluene 10.4118551238
MESH:D009336 Necrosis 2,6-dinitrotoluene 10.4118551238 7678174
MESH:D009362 Neoplasm Metastasis 4,4'-diaminodiphenylmethane 9.523581430
MESH:D009362 Neoplasm Metastasis Doxorubicin 9.5218259882
MESH:D009362 Neoplasm Metastasis Tamoxifen 9.5219393235
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.5219410462
MESH:D009369 Neoplasms sodium arsenite 2.5011559025
MESH:D009374 Neoplasms, Experimental sodium arsenite 3.6820056578
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 4.0319189210 19196722 19200415
MESH:D009401 Nephrosis Doxorubicin 4.7816636307 16899518
MESH:D009404 Nephrotic Syndrome Doxorubicin 4.0015640375 16889571
MESH:D009410 Nerve Degeneration Paraquat 3.7216893418
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 3.2214600291
MESH:D009436 Neural Tube Defects 4,4'-diaminodiphenylmethane 7.276679447
MESH:D009436 Neural Tube Defects sodium arsenite 7.2712854658
MESH:D009447 Neuroblastoma Doxorubicin 3.2615555623
MESH:D009503 Neutropenia Vinblastine 4.5817378895
MESH:D009784 Occupational Diseases 2,4-dinitrotoluene 15.0916049721 12819281
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 15.0916049721
MESH:D009784 Occupational Diseases 4,4'-diaminodiphenylmethane 15.094026338 6482804
MESH:D009902 Optic Neuritis 4,4'-diaminodiphenylmethane 5.053988306
MESH:D012516 Osteosarcoma Doxorubicin 4.1115930896
MESH:D010051 Ovarian Neoplasms sodium arsenite 2.4317306315 15276417
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.6911578682
MESH:D010212 Papilloma 4,4'-diaminodiphenylmethane 3.507296757
MESH:D010300 Parkinson Disease Paraquat 2.8112911755 15824117 11124998 11181820 11445065 15451049 16510128 16140633
MESH:D010302 Parkinson Disease, Secondary Paraquat 4.4416190885
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.2812520081
MESH:D016491 Peripheral Vascular Diseases Cadmium 5.4015687053
MESH:D010787 Photosensitivity Disorders 4,4'-diaminodiphenylmethane 4.506228378
MESH:D003557 Phyllodes Tumor Doxorubicin 5.1917983394
MESH:D010954 Plasmacytoma Selenium 4.9215087411
MESH:D010997 Pleural Neoplasms Doxorubicin 5.1917638057
MESH:D011014 Pneumonia Paraquat 4.4712504350
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.5718163543
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 3.2111222880 11118676 11896295 11399792
MESH:D011471 Prostatic Neoplasms Cadmium 1.8817075824
MESH:D011471 Prostatic Neoplasms Doxorubicin 1.8815897917 16868541 16729912 18437689 15749863 16888761
MESH:D011471 Prostatic Neoplasms sodium arsenite 1.8816039940
MESH:D011471 Prostatic Neoplasms Tamoxifen 1.8815067354
MESH:D011471 Prostatic Neoplasms Vitamin E 1.8815084515
MESH:D011537 Pruritus Ethinyl Estradiol 3.3315861022 16919318
MESH:D011658 Pulmonary Fibrosis Paraquat 2.9116324872 17997886
MESH:D051437 Renal Insufficiency Doxorubicin 4.2317922066
MESH:D012128 Respiratory Distress Syndrome, Adult Paraquat 3.9111700416
MESH:D012135 Respiratory Sounds Paraquat 4.0711874814
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.8518990726
MESH:D012162 Retinal Degeneration 4,4'-diaminodiphenylmethane 8.923692021
MESH:D012162 Retinal Degeneration Paraquat 8.9216458197
MESH:D012509 Sarcoma Doxorubicin 3.9915625365 15675481 16767912 17203757 17710206 18313854
MESH:D012512 Sarcoma, Ewing's Doxorubicin 4.2514601052 16326096
MESH:D012514 Sarcoma, Kaposi Doxorubicin 4.8117846226
MESH:D012640 Seizures 2,4-dinitrotoluene 5.8718551238
MESH:D012640 Seizures 2,6-dinitrotoluene 5.8718551238
MESH:D012871 Skin Diseases Vitamin E 2.4418709164
MESH:D012878 Skin Neoplasms Doxorubicin 9.4915692506
MESH:D012878 Skin Neoplasms sodium arsenite 9.4919524636 18572023
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 9.4916192470
MESH:D012983 Soft Tissue Neoplasms Doxorubicin 4.5816767912 17203757 15625365
MESH:D013088 Spermatocele Ethinyl Estradiol 11.6616709447
MESH:D013088 Spermatocele Tamoxifen 11.6616709447
MESH:D013119 Spinal Cord Injuries Tamoxifen 4.0619457130
MESH:D016135 Spinal Dysraphism sodium arsenite 3.8012854658
MESH:D020521 Stroke Vitamin E 3.5216517955
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.6311994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.1515669648
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.9312697716
MESH:D013964 Thyroid Neoplasms 4,4'-diaminodiphenylmethane 7.276587162 1399818 7505956 6582329 3712494
MESH:D013964 Thyroid Neoplasms Doxorubicin 7.2716010429 17909728
MESH:D001749 Urinary Bladder Neoplasms 2,4-dinitrotoluene 19.9116049721
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 19.9116049721
MESH:D001749 Urinary Bladder Neoplasms 4,4'-diaminodiphenylmethane 19.918074119
MESH:D001749 Urinary Bladder Neoplasms Doxorubicin 19.9117653716
MESH:D001749 Urinary Bladder Neoplasms sodium arsenite 19.9117306315 11723127 16712894 16452187
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 19.9116712894 8653321 17572228
MESH:D014571 Urologic Neoplasms 2,4-dinitrotoluene 12.0610091137
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 12.0610091137
MESH:D002583 Uterine Cervical Neoplasms sodium arsenite 3.7711813266
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 3.3114692618
MESH:D014625 Vaginal Neoplasms Vinblastine 5.0615577323
MESH:D014652 Vascular Diseases sodium arsenite 4.4417056641
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.6212125929
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.5414671159 15869587
MESH:D018487 Ventricular Dysfunction, Left Doxorubicin 4.2317638931 17334414 17678736 16364871
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.2815886252
Pathway ID Pathway Name
KEGG:04520 Adherens junction
KEGG:00740 Riboflavin metabolism
Pharmacogenomics Knowledge Base Top
Drug Bank Top
Drugbank ID Action Drug Name Description
DB00173 - Adenine Dietary supplement;Micronutrient
DB04214 - 4-Nitrophenyl Phosphate Indicators and Reagents;Chromogenic Compounds
No data
No data
No data

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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